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Volumn 37, Issue 13, 2009, Pages

Efficient silencing of gene expression with modular trimeric Pol II expression cassettes comprising microRNA shuttles

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; RNA POLYMERASE II; TRIMERIC ANTI HEPATITIS B VIRUS RNA POLYMERASE II; UNCLASSIFIED DRUG;

EID: 67949104971     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkp446     Document Type: Article
Times cited : (65)

References (29)
  • 1
    • 33645148088 scopus 로고    scopus 로고
    • The silent treatment: SiRNAs as small molecule drugs
    • Dykxhoorn,D.M., Palliser,D. and Lieberman,J. (2006) The silent treatment: SiRNAs as small molecule drugs. Gene Ther., 13, 541-552.
    • (2006) Gene Ther , vol.13 , pp. 541-552
    • Dykxhoorn, D.M.1    Palliser, D.2    Lieberman, J.3
  • 2
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros,V. (2004) The functions of animal microRNAs. Nature, 431 350-355.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 3
    • 44349178186 scopus 로고    scopus 로고
    • Expressed anti-HBV primary microRNA shuttles inhibit viral replication efficiently in vitro and in vivo
    • Ely,A., Naidoo,T., Mufamadi,S., Crowther,C. and Arbuthnot,P. (2008) Expressed anti-HBV primary microRNA shuttles inhibit viral replication efficiently in vitro and in vivo. Mol. Ther., 16, 1105-1112.
    • (2008) Mol. Ther , vol.16 , pp. 1105-1112
    • Ely, A.1    Naidoo, T.2    Mufamadi, S.3    Crowther, C.4    Arbuthnot, P.5
  • 4
    • 44349164025 scopus 로고    scopus 로고
    • Inhibition of HIV-1 by multiple siRNAs expressed from a single microRNA polycistron
    • Liu,Y.P., Haasnoot,J., ter Brake,O., Berkhout,B. and Konstantinova,P. (2008) Inhibition of HIV-1 by multiple siRNAs expressed from a single microRNA polycistron. Nucleic Acids Res., 36, 2811-2824.
    • (2008) Nucleic Acids Res , vol.36 , pp. 2811-2824
    • Liu, Y.P.1    Haasnoot, J.2    ter Brake, O.3    Berkhout, B.4    Konstantinova, P.5
  • 5
    • 58149232358 scopus 로고    scopus 로고
    • Artificial microRNAs as siRNA shuttles: Improved safety as compared to shRNAs in vitro and in vivo
    • Boudreau,R.L., Martins,I. and Davidson,B.L. (2009) Artificial microRNAs as siRNA shuttles: Improved safety as compared to shRNAs in vitro and in vivo. Mol. Ther., 17, 169-175.
    • (2009) Mol. Ther , vol.17 , pp. 169-175
    • Boudreau, R.L.1    Martins, I.2    Davidson, B.L.3
  • 7
    • 56349155978 scopus 로고    scopus 로고
    • Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs
    • Aagaard,L.A., Zhang,J., von Eije,K.J., Li,H., Saetrom,P., Amarzguioui,M. and Rossi,J.J. (2008) Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs. Gene Ther., 15, 1536-1549.
    • (2008) Gene Ther , vol.15 , pp. 1536-1549
    • Aagaard, L.A.1    Zhang, J.2    von Eije, K.J.3    Li, H.4    Saetrom, P.5    Amarzguioui, M.6    Rossi, J.J.7
  • 9
    • 11844297347 scopus 로고    scopus 로고
    • Use of RNA polymerase II to transcribe artificial microRNAs
    • Zeng,Y., Cai,X. and Cullen,B.R. (2005) Use of RNA polymerase II to transcribe artificial microRNAs. Methods Enzymol., 392, 371-380.
    • (2005) Methods Enzymol , vol.392 , pp. 371-380
    • Zeng, Y.1    Cai, X.2    Cullen, B.R.3
  • 10
    • 4444230672 scopus 로고    scopus 로고
    • Structural requirements for pre-microRNA binding and nuclear export by Exportin 5
    • Zeng,Y. and Cullen,B.R. (2004) Structural requirements for pre-microRNA binding and nuclear export by Exportin 5. Nucleic Acids Res., 32, 4776-4785.
    • (2004) Nucleic Acids Res , vol.32 , pp. 4776-4785
    • Zeng, Y.1    Cullen, B.R.2
  • 11
    • 0036294527 scopus 로고    scopus 로고
    • Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
    • Zeng,Y., Wagner,E.J. and Cullen,B.R. (2002) Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol. Cell, 9, 1327-1333.
    • (2002) Mol. Cell , vol.9 , pp. 1327-1333
    • Zeng, Y.1    Wagner, E.J.2    Cullen, B.R.3
  • 12
    • 57049105313 scopus 로고    scopus 로고
    • Efficient inhibition of hepatitis B virus replication in vivo using peg-modified adenovirus vectors
    • Crowther,C., Ely,A., Hornby,J., Mufamadi,M.S., Salazar,F., Marion,P. and Arbuthnot,P. (2008) Efficient inhibition of hepatitis B virus replication in vivo using peg-modified adenovirus vectors. Hum. Gene Ther, 19, 1325-1331.
    • (2008) Hum. Gene Ther , vol.19 , pp. 1325-1331
    • Crowther, C.1    Ely, A.2    Hornby, J.3    Mufamadi, M.S.4    Salazar, F.5    Marion, P.6    Arbuthnot, P.7
  • 14
    • 0026695732 scopus 로고
    • The arginine-rich domain of the hepatitis B virus core protein is required for pregenome encapsidation and productive viral positive-strand DNA synthesis but not for virus assembly
    • Nassal,M. (1992) The arginine-rich domain of the hepatitis B virus core protein is required for pregenome encapsidation and productive viral positive-strand DNA synthesis but not for virus assembly. J. Virol. 66, 4107-4116.
    • (1992) J. Virol , vol.66 , pp. 4107-4116
    • Nassal, M.1
  • 15
    • 34548316982 scopus 로고    scopus 로고
    • MicroRNA sponges: Competitive inhibitors of small RNAs in mammalian cells
    • Ebert,M.S., Neilson,J.R. and Sharp,P.A. (2007) MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat. Methods 4, 721-726.
    • (2007) Nat. Methods , vol.4 , pp. 721-726
    • Ebert, M.S.1    Neilson, J.R.2    Sharp, P.A.3
  • 17
    • 0036251639 scopus 로고    scopus 로고
    • Effective expression of small interfering RNA in human cells
    • Paul,C.P., Good,P.D., Winer,I. and Engelke,D.R. (2002) Effective expression of small interfering RNA in human cells. Nat. Biotechnol. 20, 505-508.
    • (2002) Nat. Biotechnol , vol.20 , pp. 505-508
    • Paul, C.P.1    Good, P.D.2    Winer, I.3    Engelke, D.R.4
  • 20
    • 0042121256 scopus 로고    scopus 로고
    • Mfold web server for nucleic acid folding and hybridization prediction
    • Zuker,M. (2003) Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res., 31, 3406-3415.
    • (2003) Nucleic Acids Res , vol.31 , pp. 3406-3415
    • Zuker, M.1
  • 21
    • 34247505008 scopus 로고    scopus 로고
    • Effective anti-hepatitis B virus hammerhead ribozymes derived from multimeric precursors
    • Weinberg,M.S., Ely,A., Passman,M., Mufamadi,S.M. and Arbuthnot,P. (2007) Effective anti-hepatitis B virus hammerhead ribozymes derived from multimeric precursors. Oligonucleotides, 17, 104-112.
    • (2007) Oligonucleotides , vol.17 , pp. 104-112
    • Weinberg, M.S.1    Ely, A.2    Passman, M.3    Mufamadi, S.M.4    Arbuthnot, P.5
  • 22
    • 0037108818 scopus 로고    scopus 로고
    • Hydrodynamic injection of viral DNA: A mouse model of acute hepatitis B virus infection
    • Yang,P.L., Althage,A., Chung,J. and Chisari,F.V. (2002) Hydrodynamic injection of viral DNA: A mouse model of acute hepatitis B virus infection. Proc. Natl Acad. Sci. USA, 99, 13825-13830.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 13825-13830
    • Yang, P.L.1    Althage, A.2    Chung, J.3    Chisari, F.V.4
  • 23
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • Lagos-Quintana,M., Rauhut,R., Lendeckel,W. and Tuschl,T. (2001) Identification of novel genes coding for small expressed RNAs. Science, 294, 853-858.
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 26
    • 13744250051 scopus 로고    scopus 로고
    • Computational design of antiviral RNA interference strategies that resist human immunodeficiency virus escape
    • Leonard,J.N. and Schaffer,D.V. (2005) Computational design of antiviral RNA interference strategies that resist human immunodeficiency virus escape. J. Virol., 79, 1645-1654.
    • (2005) J. Virol , vol.79 , pp. 1645-1654
    • Leonard, J.N.1    Schaffer, D.V.2
  • 28
    • 0034099208 scopus 로고    scopus 로고
    • Putative role of hepatitis B virus X protein in hepatocarcinogenesis: Effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways
    • Arbuthnot,P., Capovilla,A. and Kew,M. (2000) Putative role of hepatitis B virus X protein in hepatocarcinogenesis: Effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways. J. Gastroenterol. Hepatol., 15, 357-368.
    • (2000) J. Gastroenterol. Hepatol , vol.15 , pp. 357-368
    • Arbuthnot, P.1    Capovilla, A.2    Kew, M.3
  • 29
    • 0030133133 scopus 로고    scopus 로고
    • Hepatitis B virus transcriptional activators: Mechanisms and possible role in oncogenesis
    • Henkler,F.F. and Koshy,R. (1996) Hepatitis B virus transcriptional activators: Mechanisms and possible role in oncogenesis. J. Viral. Hepat., 3, 109-121.
    • (1996) J. Viral. Hepat , vol.3 , pp. 109-121
    • Henkler, F.F.1    Koshy, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.