Dynamics of micronuclei in rat skin fibroblasts after X irradiation

Radiation Research

Volumn 172, Issue 1, 2009, Pages 106-113

  Kaspler, P ^a   Pintilie, M ^a   Hill, R P ^a,b  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; FEMALE; LEWIS RAT; MICRONUCLEUS; MICRONUCLEUS TEST; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; RAT; SKIN DEFECT; SKIN FIBROBLAST; X IRRADIATION; AGING; ANALYSIS OF VARIANCE; ANIMAL; CYTOLOGY; FIBROBLAST; HUMAN; RADIATION EXPOSURE; RADIATION RESPONSE; SKIN; TIME;

RATTUS;

AGING; ANALYSIS OF VARIANCE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; FIBROBLASTS; HUMANS; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MICRONUCLEUS TESTS; RATS; RATS, INBRED LEW; SKIN; TIME FACTORS;

EID: 67949091171     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR1649.1     Document Type: Article

References (23)

1. R. P. Hill, P. Kaspler, A. M. Griffin, B. O'Sullivan, C. Catton, H. Alasti, A. Abbas, M. Heydarian, P. Ferguson and R. S. Bell, Studies of the in vivo radiosensitivity of human skin fibroblasts. Radiother. Oncol. 84, 75-83 (2007).
2. D. Dantzer, P. Ferguson, R. P. Hill, A. Keating, R. A. Kandel, J. S. Wunder, B. O'Sullivan, J. Sandhu, J. Waddell and R. S. Bell, Effect of radiation and cell implantation on wound healing in a rat model. J. Surg. Oncol. 83, 185-190 (2003).
3. P. C. Ferguson, E. L. Boynton, J. S. Wunder, R. P. Hill, B. O'Sullivan, J. S. Sandhu and R. S. Bell, Intradermal injection of autologous dermal fibroblasts improves wound healing in irradiated skin. J. Surg. Res. 85, 331-338 (1999).
4. R. Gorodetsky, W. H. McBride and H. R. Withers, Assay of radiation effects in mouse skin as expressed in wound healing. Radiat. Res. 116, 135-144 (1988).
5. T. Kunisada, S. Y. Ngan, G. Powell and P. F. Choong, Wound complications following pre-operative radiotherapy for soft tissue sarcoma. Eur. J. Surg. Oncol. 28, 75-79 (2002).
6. B. O'Sullivan, A. M. Davis, R. Turcotte, R. Bell, C. Catton, P. Chabot, J. Wunder, R. Kandel, K. Goddard and B. Zee, Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomised trial. Lancet 359, 2235-2241 (2002).
7. C. Nieder, L. Milas and K. K. Ang, Tissue tolerance to reirradiation. Semin. Radiat. Oncol. 10, 200-209 (2000).
8. F. A. Stewart, Re-treatment after full-course radiotherapy: is it a viable option? Acta Oncol. 38, 855-862 (1999).
9. J. Brush, S. L. Lipnick, T. Phillips, J. Sitko, J. T. McDonald and W. H. McBride, Molecular mechanisms of late normal tissue injury. Semin. Radiat. Oncol. 17, 121-130 (2007).
10. R. G. Bristow and R. P. Hill, Comparison between in vitro radiosensitivity and in vivo radioresponse in murine tumor cell lines. II: In vivo radioresponse following fractionated treatment and in vitro/in vivo correlations. Int. J. Radiat. Oncol. Biol. Phys. 18, 331-345 (1990).
11. M. A. Khan, R. P. Hill and J. Van Dyk, Partial volume rat lung irradiation: an evaluation of early DNA damage. Int. J. Radiat. Oncol. Biol. Phys. 40, 467-476 (1998).
12. M. A. Khan, J. Van Dyk, I. W. Yeung and R. P. Hill, Partial volume rat lung irradiation; assessment of early DNA damage in different lung regions and effect of radical scavengers. Radiother. Oncol. 66, 95-102 (2003).
13. M. Fenech, The in vitro micronucleus technique. Mutat. Res. 455, 81-95 (2000).
14. R. P. Hill, Radiation effects on the respiratory system. Br. J. Radiol. Suppl. 27, 75-81 (2005).
15. A. R. Langan, M. A. Khan, I. W. Yeung, J. Van Dyk and R. P. Hill, Partial volume rat lung irradiation: the protective/mitigating effects of Eukarion-189, a superoxide dismutase-catalase mimetic. Radiother. Oncol. 79, 231-238 (2006).
16. V. L. Calveley, M. A. Khan, I. W. Yeung, J. Vandyk and R. P. Hill, Partial volume rat lung irradiation: temporal fluctuations of in-field and out-of-field DNA damage and inflammatory cytokines following irradiation. Int. J. Radiat. Biol. 81, 887-899 (2005).
17. G. Joksic, S. Petrovic and Z. Ilic, Age-related changes in radiation-induced micronuclei among healthy adults. Braz. J. Med. Biol. Res. 37, 1111-1117 (2004).
18. C. Herskind, J. Johansen, S. M. Bentzen, M. Overgaard, J. Overgaard, M. Bamberg and H. P. Rodemann, Fibroblast differentiation in subcutaneous fibrosis after postmastectomy radiotherapy. Acta Oncol. 39, 383-388 (2000).
19. K. Bayreuther, H. P. Rodemann, R. Hommel, K. Dittmann, M. Albiez and P. I. Francz, Human skin fibroblasts in vitro differentiate along a terminal cell lineage. Proc. Natl. Acad. Sci. USA 85, 5112-5116 (1988).
20. C. Laurent, J. P. Pouget and P. Voisin, Modulation of DNA damage by pentoxifylline and alpha-tocopherol in skin fibroblasts exposed to gamma rays. Radiat. Res. 164, 63-72 (2005).
21. G. C. Jagetia and M. Shrinath Baliga, Vincristine increases the genomic instability in irradiated cultured human peripheral blood lymphocytes. Toxicol. Lett. 126, 179-186 (2002).
22. W. P. Chang, M. S. Tsai, J. S. Hwang, Y. P. Lin, W. A. Hsieh and S. Y. Huang, Follow-up in the micronucleus frequencies and its subsets in human population with chronic low-dose gamma-irradiation exposure. Mutat. Res. 428, 99-105 (1999).
23. N. H. Terry, S. L. Tucker and E. L. Travis, Time course of loss of residual radiation damage in murine skin assessed by retreatment. Int. J. Radiat. Biol. 55, 271-283 (1989).