Follow-up in the micronucleus frequencies and its subsets in human population with chronic low-dose γ-irradiation exposure

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 428, Issue 1-2, 1999, Pages 99-105

  Chang, Wushou P ^a,b   Tsai, Mon Shiung ^a   Hwang, Jing Shiang ^c   Lin, Yi Ping ^a   Hsieh, Wan Hwa A ^a   Shao Yi, Huang ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b JEN AI HOSPITAL   (Taiwan)

^c INSTITUTE OF STATISTICAL SCIENCE   (Taiwan)

Author keywords

Irradiation; Human lymphocyte; Micronucleus frequency; Multi; Single

Indexed keywords

CYTOCHALASIN B;

ADOLESCENT; ADULT; CHILD; CLINICAL ARTICLE; CONFERENCE PAPER; CYTOGENETICS; DNA DAMAGE; FEMALE; FOLLOW UP; GAMMA IRRADIATION; HUMAN; HUMAN CELL; LYMPHOCYTE; MALE; MICRONUCLEUS; MICRONUCLEUS TEST; PRIORITY JOURNAL;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; COBALT RADIOISOTOPES; CONSTRUCTION MATERIALS; CYTOCHALASIN B; ENVIRONMENTAL EXPOSURE; FEMALE; FOLLOW-UP STUDIES; GAMMA RAYS; HUMANS; LYMPHOCYTES; MALE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MICRONUCLEUS TESTS; MIDDLE AGED; TAIWAN; TIME FACTORS;

EID: 0032785388     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5742(99)00036-8     Document Type: Conference Paper

References (27)

1. Chang W.P., Chan C.C., Wang J.D. Cobalt-60 contamination in the recycled steel rods resulting in massive civilian overexposure: causes and challenges. Health Phys. 73:1997;465-472.
2. Chang W.P., Kau J. Taiwan: exposure to high doses of radiation. Lancet. 341:1993;750.
3. Chang W.P. Spread of Taiwan's radiation panic. Lancet. 342:1993;1544.
4. W.P. Chang, Health effects of chronic low-dose exposure in human population, International Conference, Diagnosis and Treatment of Radiation Injury, DOE/EU/ISPN/ERU Series, World Scientific Publication, 1999, in press.
5. Cardarelli J. II, Elliott L., Hornung R., Chang W.P. Proposed model for estimating dose to inhabitants of Co-60 contaminated buildings. Health Phys. 72:1997;351-360.
6. Hwang J.S., Chan C.C., Wang J.D., Chang W.P. Modeling for radiation exposure in living spaces of apartments with multiple radioactive sources. Health Phys. 74:1998;379-386.
7. Chang W.P., Lee S.R., Tu J.R., Hseu S.S. Increased micronucleus formation in nurses with occupational nitrous oxide exposure in operating theaters. Environ. Mol. Mutagen. 27:1996;93-97.
8. Chang W.P., Hwang B.F., Wang D., Wang J.D. Chronic low-dose, low-dose rate radiation exposure induced an increased frequency of micronuclei in lymphocytes from residents of radioactive buildings in Taiwan. Lancet. 350:1997;330-333.
9. Duffaud F., Orsie T., Villani P., Pelissier A.L., Volot F., Favre R., Botta A. Comparison between micronucleated lymphocyte rates observed in healthy subjects and cancer patients. Mutagenes. 12:1997;227-231.
10. Chang W.P., Little L.B. Persistently elevated frequency of spontaneous mutations in progeny of CHO clones surviving X-irradiation: association with delayed reproductive death phenotype. Mutat. Res. 270:1992;191-199.
11. Niwa O., Kamiya K., Furihata C., Nitta Y., Wang Z., Fan Y.J., Ninomiya Y., Kotomura N., Numoto M., Kominami R. Association of minisatellite instability with c-myc amplification and K-ras mutation in methylcholanthrene-induced mouse sarcomas. Cancer Res. 55:1995;5670-5676.
12. Fenech M., Morley A.A. Cytokinesis-block micronucleus method in human lymphocytes: effect of in vivo aging and low dose X-irradiation. Mutat. Res. 161:1986;193-198.
13. Fenech M., Neville S. Conversion of excision-repairable DNA lesions to micronuclei within one cell cycle in human lymphocytes. Environ. Mol. Mutagen. 19:1992;27-36.
14. da Cruz A.D., McArthur A.G., Silva C.C., Curado M.P., Glickman B.W. Human micronucleus counts are correlated with age, smoking, and cesium-137 dose in the Goiania (Brazil) radiological accident. Mutat. Res. 313:1994;57-68.
15. 131I therapy for thyroid cancer Int. J. Radiat. Biol. 69:1996;259-268.
16. Fenech M., Denham J., Francis W., Morley A. Micronuclei in cytokinesis-blocked lymphocytes of cancer patients following fractionated partial-body radiotherapy. Int. J. Radiat. Biol. 57:1990;373-383.
17. W.P. Chang, M.H. Tsai, Y.P. Lin, J.S. Hwang, B.F. Hwang, W.A. Hsieh, Modeling changes in lymphocyte micronucleus frequencies in people after cessation of chronic low-dose radiation exposure (1999) submitted.
18. Chen J.J., Hwang J.S., Tsong Y. Estimation of the shelf-life of drugs with mixed effects models. J. Biopharm. Stat. 5:1995;131-140.
19. R.C. Little, G.A. Milliken, W.W. Stroup, R.D. Wolfinger, SAS System for Mixed Models, 1st edn., SAS Institute, Cary, NC, USA, 1996.
20. Fenech M., Morley A.A. Kinetochore detection in micronuclei: an alternative method for measuring chromosome loss. Mutagenes. 4:1989;98-104.
21. Abend M., Rhein A., Gilbertz K.P., Blakely W.F., Beuningen D.V. Correlation of micronucleus and apoptosis assays with reproductive cell death. Int. J. Radiat. Biol. 67:1995;315-326.
22. M. Fenech, N. Holland, W.P. Chang, E. Zeiger, S. Bonassi, The HUMN Project - an international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans, Mutat. Res., submitted and presented in the 3rd International Conference of Environmental Mutagen on Human Population, Thailand, Bangkok, December, 1999.
23. K.E. Buckton, Chromosome Aberrations in Patients Treated with X-irradiation for Ankylosing Spondylitis. Radiation-induced Chromosome Damage in Man, Alan R. Liss, New York, 1983, pp. 491-511.
24. 131I Cancer Lett. 91:1995;199-204.
25. Little J.B., Nagasawa H., Pfenning T., Vetros H. Radiation-induced genomic instability: delayed mutagenesis and cytogenetic effects of X-ray and alpha particles. Radiat. Res. 148:1997;299-307.
26. Sawyer J.R., Swanson C.M., Wheeler G., Cunniff C. Chromosome instability in ICF syndrome: formation of micronuclei from multibranched chromosomes 1 demonstrated by fluorescence in situ hybridization. Am. J. Med. Genet. 56:1995;203-209.
27. Weissenborn U., Streffer C. Micronuclei with kinetochores in human melanoma cells and rectal carcinomas. Int. J. Radiat. Biol. 59:1991;373-383.