Regulation and role of suppressor of cytokine signaling-3 in hypothalamic 4B cells

Journal of Endocrinology

Volumn 201, Issue 3, 2009, Pages 369-376

  Kageyama, Kazunori ^a   Hanada, Komaki ^a   Iwasaki, Yasumasa ^b   Suda, Toshihiro ^a  

^a HIROSAKI UNIVERSITY   (Japan)

^b KOCHI MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FORSKOLIN; INTERLEUKIN 6; JANUS KINASE INHIBITOR; MESSENGER RNA; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; JANUS KINASE; PROTEIN KINASE INHIBITOR; SOCS3 PROTEIN, RAT; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE INTERACTION; GENE REPRESSION; HYPOTHALAMUS PERIVENTRICULAR NUCLEUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; ANIMAL; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HYPOTHALAMUS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROMOTER REGION;

ANIMALS; CELL LINE; CORTICOTROPIN-RELEASING HORMONE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FORSKOLIN; GENE EXPRESSION REGULATION; HYPOTHALAMUS; INTERLEUKIN-6; JANUS KINASES; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN KINASE INHIBITORS; RATS; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 67849124336     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1677/JOE-08-0506     Document Type: Article

References (28)

1. Agarwal A, Halvorson LM & Legradi G 2005 Pituitary adenylate cyclaseactivating polypeptide (PACAP) mimics neuroendocrine and behavioral manifestations of stress: evidence for PKA-mediated expression of the corticotropin-releasing hormone (CRH) gene. Brain Research. Molecular Brain Research 138 45-57.
2. Auernhammer CJ, Bousquet C & Melmed S 1999 Autoregulation of pituitary corticotroph SOCS-3 expression: characterization of the murine SOCS-3 promoter. PNAS 96 6964-6969.
3. Bousquet C, Chesnokova V, Kariagina A, Ferrand A & Melmed S 2001 cAMP neuropeptide agonists induce pituitary suppressor of cytokine signaling-3: novel negative feedback mechanism for corticotroph cytokine action. Molecular Endocrinology 15 1880-1890.
4. Cheng YH, Nicholson RC, King B, Chan EC, Fitter JT & Smith R 2000 Glucocorticoid stimulation of corticotropin-releasing hormone gene expression requires a cyclic adenosine 3′,5′-monophosphate regulatory element in human primary placental cytotrophoblast cells. Journal of Clinical Endocrinology and Metabolism 85 1937-1945.
5. Chesnokova V & Melmed S 2002 Neuro-immuno-endocrine modulation of the hypothalamic-pituitary-adrenal (HPA) axis by gp130 signaling molecules. Endocrinology 143 1571-1574.
6. Ehlting C, Häussinger D & Bode JG 2005 Sp3 is involved in the regulation of SOCS3 gene expression. Biochemical Journal 387 737-745.
7. Itoi K, Horiba N, Tozawa F, Sakai Y, Sakai K, Abe K, Demura H & Suda T 1996 Major role of 3′,5′-cyclic adenosine monophosphate-dependent protein kinase A pathway in corticotropin-releasing factor gene expression in the rat hypothalamus in vivo. Endocrinology 137 2389-2396.
8. Kageyama K, Hanada K, Iwasaki Y, Sakihara S, Nigawara T, Kasckow J & Suda T 2007 Pituitary adenylate cyclase-activating polypeptide stimulates corticotropin-releasing factor, vasopressin and interleukin-6 gene transcription in hypothalamic 4B cells. Journal of Endocrinology 195 199-211.
9. Karalis K, Muglia LJ, Bae D & Hilderbrand JA 1997 CRH and the immune system. Journal of Neuroimmunology 72 131-136.
10. Kasckow J, Mulchahey JJ, Aguilera G, Pisarska M, Nikodemova M, Chen HC, Herman JP, Murphy EK, Liu Y, Rizvi TA et al. 2003 Corticotropinreleasing hormone (CRH) expression and protein kinase A mediated CRH receptor signalling in an immortalized hypothalamic cell line. Journal of Neuroendocrinology 15 521-529.
11. King BR, Smith R & Nicholson RC 2002 Novel glucocorticoid and cAMP interactions on the CRH gene promoter. Molecular and Cellular Endocrinology 194 19-28.
12. Krebs DL & Hilton DJ 2000 SOCS: physiological suppressors of cytokine signaling. Journal of Cell Science 113 2813-2819.
13. Liu Y, Kalintchenko N, Sassone-Corsi P & Aguilera G 2006 Inhibition of corticotrophin-releasing hormone transcription by inducible cAMP-early repressor in the hypothalamic cell line, 4B. Journal of Neuroendocrinology 18 42-49.
14. Livak KJ & Schmittgen TD 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2(KDelta Delta C(t)) method. Methods 25 402-408.
15. Moriyama T, Kageyama K, Kasagi Y, Iwasaki Y, Nigawara T, Sakihara S & Suda T 2005 Differential regulation of corticotropin-releasing factor receptor type 1 (CRF1 receptor) mRNA via protein kinase A and mitogen-activated protein kinase pathways in rat anterior pituitary cells. Molecular and Cellular Endocrinology 243 74-79.
16. Navarra P, Tsagarakis S, Faria MS, Rees LH, Besser GM & Grossman AB 1991 Interleukins-1 and -6 stimulate the release of corticotropin-releasing hormone-41 from rat hypothalamus in vitro via the eicosanoid cyclooxygenase pathway. Endocrinology 128 37-44.
17. Nikodemova M, Kasckow J, Liu H,Manganiello V & Aguilera G 2003 Cyclic adenosine 3′,5′-monophosphate regulation of corticotropin-releasing hormone promoter activity in AtT-20 cells and in a transformed hypothalamic cell line. Endocrinology 144 1292-1300.
18. Ram PA & Waxman DJ 1999 SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms. Journal of Biological Chemistry 274 35553-35561.
19. Schmitz J, Weissenbach M, Haan S, Heinrich PC & Schaper F 2000 SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130. Journal of Biological Chemistry 275 12848-12856.
20. Seasholtz AF, Thompson RC & Douglass JO 1988 Identification of a cyclic adenosine monophosphate-responsive element in the rat corticotropinreleasing hormone gene. Molecular Endocrinology 2 1311-1319.
21. Spengler D, Rupprecht R, Van LP & Holsboer F 1992 Identification and characterization of a 3′,5′-cyclic adenosine monophosphate-responsive element in the human corticotropin-releasing hormone gene promoter. Molecular Endocrinology 6 1931-1941.
22. Suda T, Yajima F, Tomori N, Demura H & Shizume K 1985 In vitro study of immunoreactive corticotropin-releasing factor release from the rat hypothalamus. Life Sciences 37 1499-1505.
23. Suda T, Kageyama K, Sakihara S & Nigawara T 2004 Physiological roles of urocortins, human homologues of fish urotensin 1, and their receptors. Peptides 25 1689-1701.
24. Turnbull AV & Rivier CL 1999 Regulation of the hypothalamic-pituitaryadrenal axis by cytokines: actions and mechanisms of action. Physiological Reviews 79 1-71.
25. Vale W, Spiess J, Rivier C & Rivier J 1981 Characterization of a 41 residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin. Science 213 1394-1397.
26. Vallieres L & Rivest S 1999 Interleukin-6 is a needed proinflammatory cytokine in the prolonged neural activity and transcriptional activation of corticotropin-releasing factor during endotoxemia. Endocrinology 140 3890-3903.
27. Venihaki M, Dikkes P, Carrigan A & Karalis KP 2001 Corticotropin-releasing hormone regulates IL-6 expression during inflammation. Journal of Clinical Investigation 108 1159-1166.
28. Whitnall MH 1993 Regulation of the hypothalamic corticotropin-releasing hormone neurosecretory system. Progress in Neurobiology 40 573-629.