Gestational treatment with methylazoxymethanol (MAM) that disrupts hippocampal-dependent memory does not alter behavioural response to cocaine

Pharmacology Biochemistry and Behavior

Volumn 93, Issue 4, 2009, Pages 382-390

  Featherstone, Robert E ^a   Burton, Christie L ^a,b   Coppa Hopman, Romina ^a   Rizos, Zoë ^a   Sinyard, Judy ^a   Kapur, Shitij ^a,b   Fletcher, Paul J ^a,b  

^a CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Animal model; Dopamine; Drug induced reinstatement; Hippocampus; Memory; Progressive ratio schedule of reinforcement; Schizophrenia; Self administration

Indexed keywords

COCAINE; METHYLAZOXYMETHANOL; SODIUM CHLORIDE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC ACTIVITY; DRUG SELF ADMINISTRATION; FEMALE; GESTATION PERIOD; HIPPOCAMPUS; LEARNING; LOCOMOTION; MEMORY DISORDER; MESOLIMBIC DOPAMINERGIC SYSTEM; NONHUMAN; PRIORITY JOURNAL; RAT; SCHIZOPHRENIA; TASK PERFORMANCE;

ALKYLATING AGENTS; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; COCAINE; COCAINE-RELATED DISORDERS; CONDITIONING, OPERANT; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTINCTION, PSYCHOLOGICAL; FEMALE; HIPPOCAMPUS; LEARNING; MAZE LEARNING; MEMORY; METHYLAZOXYMETHANOL ACETATE; MOTOR ACTIVITY; ORGAN SIZE; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; REINFORCEMENT SCHEDULE;

ANIMALIA; RATTUS;

EID: 67849119418     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2009.05.010     Document Type: Article

References (54)

1. Arnold J.M., and Roberts D.C.S. Critique of fixed and progressive ratio schedules used to examine the neural substrates of drug reinforcement. Pharmacol Biochem Behav (1997) 441-447
2. Birrell J.M., and Brown V.J. Medial frontal cortex mediates perceptual attentional set shifting in the rat. J Neurosci 20 (2000) 4320-4324
3. Caine S.B., and Koob G.F. Effects of dopamine D-1 and D-2 antagonists on cocaine self-administration under different schedules of reinforcement in the rat. J Pharmacol Exp Ther 270 (1994) 209-218
4. Carr G.D., and White N.M. Anatomical disassociation of amphetamine's rewarding and aversive effects: an intracranial microinjection study. Psychopharmacology (Berl) 89 (1986) 340-346
5. Chambers R.A., and Self D.W. Motivational responses to natural and drug rewards in rats with neonatal ventral hippocampal lesions: an animal model of dual diagnosis schizophrenia. Neuropsychopharmacology 27 (2002) 889-905
6. Chambers R.A., Krystal J.H., and Self D.W. A neurobiological basis for substance abuse comorbidity in schizophrenia. Biol Psychiatry 50 (2001) 71-83
7. Corrigall W.A., and Coen K.M. Cocaine self-administration is increased by both D1 and D2 dopamine antagonists. Pharmacol Biochem Behav 39 (1991) 799-802
8. Curran C., Byrappa N., and McBride A. Stimulant psychosis: systematic review. Br J Psychiatry 185 (2004) 196-204
9. Dalley J.W., Cardinal R.N., and Robbins T.W. Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates. Neurosci Biobehav Rev 28 (2004) 771-784
10. Davis K.L., Kahn R.S., Ko G., and Davidson M. Dopamine in schizophrenia: a review and reconceptualization. Am J Psychiatry 148 (1991) 1474-1486
11. Di Ciano P., and Everitt B.J. Contribution of the ventral tegmental area to cocaine-seeking maintained by a drug-paired conditioned stimulus in rats. Eur J Neurosci 19 (2004) 1661-1667
12. Di Ciano P., Coury A., Depoortere R.Y., Egilmez Y., Lane J.D., Emmett-Oglesby M.W., et al. Comparison of changes in extracellular dopamine concentrations in the nucleus accumbens during intravenous self-administration of cocaine or d-amphetamine. Behav Pharmacol 6 (1995) 311-322
13. Featherstone R.E., Rizos Z., Nobrega J.N., Kapur S., and Fletcher P.J. Gestational methylazoxymethanol acetate treatment impairs select cognitive functions: parallels to schizophrenia. Neuropsychopharmacology 32 (2007) 483-492
14. Flagstad P., Glenthoj B.Y., and Didriksen M. Cognitive deficits caused by late gestational disruption of neurogenesis in rats: a preclinical model of schizophrenia. Neuropsychopharmacology 30 (2005) 250-260
15. Flagstad P., Mork A., Glenthoj B.Y., van Beek J., Michael-Titus A.T., and Didriksen M. Disruption of neurogenesis on gestational day 17 in the rat causes behavioral changes relevant to positive and negative schizophrenia symptoms and alters amphetamine-induced dopamine release in nucleus accumbens. Neuropsychopharmacology 29 (2004) 2052-2064
16. Fletcher P.J., Grottick A.J., and Higgins G.A. Differential effects of the 5-HT(2A) receptor antagonist M100907 and the 5-HT(2C) receptor antagonist SB242084 on cocaine-induced locomotor activity, cocaine self-administration and cocaine-induced reinstatement of responding. Neuropsychopharmacology 27 (2002) 576-586
17. Fox M.T., Barense M.D., and Baxter M.G. Perceptual attentional set-shifting is impaired in rats with neurotoxic lesions of posterior parietal cortex. J Neurosci 23 (2003) 676-681
18. Goeders N.E., and Smith J.E. Cortical dopaminergic involvement in cocaine reinforcement. Science 221 (1983) 773-775
19. Goeders N.E., Dworkin S.I., and Smith J.E. Neuropharmacological assessment of cocaine self-administration into the medial prefrontal cortex. Pharmacol Biochem Behav 24 (1986) 1429-1440
20. Gourevitch R., Rocher C., Le Pen G., Krebs M.O., and Jay T.M. Working memory deficits in adult rats after prenatal disruption of neurogenesis. Behav Pharmacol 15 (2004) 287-292
21. Hambrecht M., and Hafner H. Substance abuse and the onset of schizophrenia. Biol Psychiatry 40 (1996) 1155-1163
22. Hemby S.E., Jones G.H., Justice Jr. J.B., and Neill D.B. Conditioned locomotor activity but not conditioned place preference following intra-accumbens infusions of cocaine. Psychopharmacology (Berl) 106 (1992) 330-336
23. Hemby S.E., Jones G.H., Neill D.B., and Justice Jr. J.B. 6-Hydroxydopamine lesions of the medial prefrontal cortex fail to influence cocaine-induced place conditioning. Behav Brain Res 49 (1992) 225-230
24. Hoebel B.G., Monaco A.P., Hernandez L., Aulisi E.F., Stanley B.G., and Lenard L. Self-injection of amphetamine directly into the brain. Psychopharmacology (Berl) 81 (1983) 158-163
25. Horger B.A., Shelton K., and Schenk S. Preexposure sensitizes rats to the rewarding effects of cocaine. Pharmacol Biochem Behav 37 (1990) 707-711
26. Kapur S., and Remington G. Dopamine D(2) receptors and their role in atypical antipsychotic action: still necessary and may even be sufficient. Biol Psychiatry 50 (2001) 873-883
27. Kuczenski R., and Segal D. Concomitant characterization of behavioral and striatal neurotransmitter response to amphetamine using in vivo microdialysis. J Neurosci 9 (1989) 2051-2065
28. Laruelle M., Abi-Dargham A., Gil R., Kegeles L., and Innis R. Increased dopamine transmission in schizophrenia: relationship to illness phases. Biol Psychiatry 46 (1999) 56-72
29. Laruelle M., Abi-Dargham A., van Dyck C.H., Gil R., D'Souza C.D., Erdos J., et al. Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects. Proc Natl Acad Sci U S A 93 (1996) 9235-9240
30. Le Pen G., Gourevitch R., Hazane F., Hoareau C., Jay T.M., and Krebs M.O. Peri-pubertal maturation after developmental disturbance: a model for psychosis onset in the rat. Neuroscience 143 (2006) 395-405
31. Lillrank S.M., Lipska B.K., and Weinberger D.R. Neurodevelopmental animal models of schizophrenia. Clin Neurosci 3 (1995) 98-104
32. Lipska B.K., Lerman D.N., Khaing Z.Z., and Weinberger D.R. The neonatal ventral hippocampal lesion model of schizophrenia: effects on dopamine and GABA mRNA markers in the rat midbrain. Eur J Neurosci 18 (2003) 3097-3104
33. Lyness W.H., Friedle N.M., and Moore K.E. Destruction of dopaminergic nerve terminals in nucleus accumbens: effect on d-amphetamine self-administration. Pharmacol Biochem Behav 11 (1979) 553-556
34. McFarland K., and Kalivas P.W. The circuitry mediating cocaine-induced reinstatement of drug-seeking behavior. J Neurosci 21 (2001) 8655-8663
35. Moore H., Jentsch J.D., Ghajarnia M., Geyer M.A., and Grace A.A. A neurobehavioral systems analysis of adult rats exposed to methylazoxymethanol acetate on E17: implications for the neuropathology of schizophrenia. Biol Psychiatry 60 (2006) 253-264
36. Morgan M.A., Romanski L.M., and LeDoux J.E. Extinction of emotional learning: contribution of medial prefrontal cortex. Neurosci Lett 163 (1993) 109-113
37. Müller C.P., Carey R.J., and Huston J.P. Serotonin as an important mediator of cocaine's behavioral effects. Drugs Today 39 (2003) 497-511
38. Pettit H.O., Ettenberg A., Bloom F.E., and Koob G.F. Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats. Psychopharmacology (Berl) 84 (1984) 167-173
39. Piazza P.V., Deminiere J.M., Le Moal M., and Simon H. Factors that predict individual vulnerability to amphetamine self-administration. Science 245 (1989) 1511-1513
40. Pierre P.J., and Vezina P. Predisposition to self-administer amphetamine: the contribution of response to novelty and prior exposure to the drug. Psychopharmacology (Berl) 129 (1997) 277-284
41. Placenza F.M., Vaccarino F.J., Fletcher P.J., and Erb S. Activation of central neurokinin-1 receptors induces reinstatement of cocaine-seeking behavior. Neurosci Lett 390 (2005) 42-47
42. Regier D.A., Farmer M.E., Rae D.S., Locke B.Z., Keith S.J., Judd L.L., et al. Comorbidity of mental disorders with alcohol and other drug abuse. Results from the Epidemiologic Catchment Area (ECA) Study. Jama 264 (1990) 2511-2518
43. Richardson N.R., and Roberts D.C. Progressive ratio schedules in drug self-administration studies in rats: a method to evaluate reinforcing efficacy. J Neurosci Methods 66 (1996) 1-11
44. Roberts D.C., and Koob G.F. Disruption of cocaine self-administration following 6-hydroxydopamine lesions of the ventral tegmental area in rats. Pharmacol Biochem Behav 17 (1982) 901-904
45. Roberts D.C., Koob G.F., Klonoff P., and Fibiger H.C. Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens. Pharmacol Biochem Behav 12 (1980) 781-787
46. Schenk S., and Partridge B. Sensitization and tolerance in psychostimulant self-administration. Pharmacol Biochem Behav 57 (1997) 543-550
47. Seeman P., Lee T., Chau-Wong M., and Wong K. Antipsychotic drug doses and neuroleptic/dopamine receptors. Nature 261 (1976) 717-719
48. Smelson D.A., Losonczy M.F., Kilker C., Starosta A., Kind J., Williams J., et al. An analysis of cue reactivity among persons with and without schizophrenia who are addicted to cocaine. Psychiatr Serv 53 (2002) 1612-1616
49. Stewart J. Stress and relapse to drug seeking: studies in laboratory animals shed light on mechanisms and sources of long-term vulnerability. Am J Addict 12 (2003) 1-17
50. Suto N., Austin J.D., Tanabe L.M., Kramer M.K., Wright D.A., and Vezina P. Previous exposure to VTA amphetamine enhances cocaine self-administration under a progressive ratio schedule in a D1 dopamine receptor dependent manner. Neuropsychopharmacology 27 (2002) 970-979
51. Tzschentke T.M., and Schmidt W.J. Differential effects of discrete subarea-specific lesions of the rat medial prefrontal cortex on amphetamine- and cocaine-induced behavioural sensitization. Cereb Cortex 10 (2000) 488-498
52. van Rossum J.M. The significance of dopamine-receptor blockade for the mechanism of action of neuroleptic drugs. Arch Int Pharmacodyn Ther 160 (1966) 492-494
53. Vezina P. Sensitization of midbrain dopamine neuron reactivity and the self-administration of psychomotor stimulant drugs. Neurosci Biobehav Rev 27 (2004) 827-839
54. Zito K.A., Vickers G., and Roberts D.C. Disruption of cocaine and heroin self-administration following kainic acid lesions of the nucleus accumbens. Pharmacol Biochem Behav 23 (1985) 1029-1036