An aldol-based synthesis of(+)-peloruside a, a potent microtubule Stabilizing Agent

Journal of the American Chemical Society

Volumn 131, Issue 11, 2009, Pages 3840-3841

  Evans, David A ^a   Welch, Dennie S ^a   Speed, Alexander W H ^a   Moniz, George A ^a   Reichelt, Andreas ^a   Ho, Stephen ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOL REACTIONS; CONVERGENT SYNTHESIS; DIASTEREOSELECTION; MARINE NATURAL PRODUCTS; METHYL KETONES; MICROTUBULE; NATURAL PRODUCTS; STABILIZING AGENTS; STEREOCENTERS; SYNTHON;

ACETONE; ADDITION REACTIONS; ALDEHYDES; BORON; BORON COMPOUNDS;

SYNTHESIS (CHEMICAL);

NATURAL PRODUCT; PACLITAXEL; PELORUSIDE A; UNCLASSIFIED DRUG; ALCOHOL DERIVATIVE; ALDEHYDE; BIOLOGICAL PRODUCT; FUSED HETEROCYCLIC RINGS; LACTONE; TUBULIN MODULATOR;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; CYCLIZATION; DRUG CYTOTOXICITY; MARINE ENVIRONMENT; METABOLITE; MICROTUBULE; NEW ZEALAND; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; SPONGE (PORIFERA); STEREOCHEMISTRY; SYNTHESIS; ANIMAL; CHEMISTRY; STEREOISOMERISM;

ALCOHOLS; ALDEHYDES; ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; BIOLOGICAL PRODUCTS; LACTONES; PORIFERA; STEREOISOMERISM; TUBULIN MODULATORS;

EID: 67849095752     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja900020a     Document Type: Article

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