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24944578566
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note
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1H NMR spectra of the bis-Mosher esters.
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24944544824
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See Supporting Information for details
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See Supporting Information for details.
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43
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0033538123
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See Supporting Information for details
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Acyloxazolidinone 20 is avalible in two steps from known α-benzyloxy-protected glycolate oxazolidinone: Haigh, D.; Birrell, H. C.; Cantello, B. C. C.; Eggleston, D. S.; Haltiwanger, R. C.; Hindley, R. M.; Ramaswamy, A.; Stevens, N. C. Tetrahedron: Asymmetry 1999, 10, 1353. See Supporting Information for details.
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Stevens, N.C.8
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44
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24944475658
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note
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We presume that the minor aldol product derives from the minor enantiomer of 18 since the % ee of the major diastereomer (determined for compound 21) was >95% by Mosher ester analysis. See Supporting Information for details.
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45
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24944465697
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note
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The relative C(3)-C(5) stereochemistry of 19 was confirmed via the Rychnovsky method. See Supporting Information for details.
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