1,5-Asymmetric induction in boron-mediated β-alkoxy methyl ketone aldol addition reactions

Journal of the American Chemical Society

Volumn 125, Issue 36, 2003, Pages 10893-10898

  Evans, David A ^a   Côté, Bernard ^a   Coleman, Paul J ^a   Connell, Brian T ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

STEREOCHEMICAL CONTROL;

ADDITION REACTIONS; CATALYSIS; STEREOCHEMISTRY;

ORGANOMETALLICS;

ACETONE; BORON; ENOLSILANE; KETONE DERIVATIVE; LEWIS ACID; SILANE DERIVATIVE; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; CHEMICAL STRUCTURE; CHIRALITY; DIASTEREOISOMER; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

ALCOHOLS; BORON; ETHERS; KETONES; KINETICS; STEREOISOMERISM; TEMPERATURE;

EID: 0041733422     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja027640h     Document Type: Article

References (36)

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36. In the aldol reaction reported by Panek (eq 23), the indicated configurations of the acetal centers in both reactant and product are currently in question. This reaction has been reinvestigated by Professor L. C. Dias (Universidade Estadual de Campinas, Instituto De Quimica-UNICAMP, Caixa Postal 6154 Campinas SPBRAZIL) who has kindly informed me of his results and of the indicated configuration reassignment.