Total synthesis of (+)-peloruside A

Organic Letters

Volumn 7, Issue 7, 2005, Pages 1303-1305

  Jin, Meizhong ^a   Taylor, Richard E ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC AGENT; EPOXIDE; PELORUSIDE A; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; COMPLEX FORMATION; CYCLIZATION; DRUG SYNTHESIS; FRAGMENTATION REACTION; METHYLATION; MOLECULAR INTERACTION; REACTION ANALYSIS;

ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; CYCLIZATION; LACTONES; MOLECULAR STRUCTURE; PORIFERA; STEREOISOMERISM;

EID: 17444403596     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol050070g     Document Type: Article

References (28)

1. West, L. M.; Northcote, P. T. J. Org. Chem. 2000, 65, 445.
2. Hood, K. A.; West, L. M.; Rouwe, B.; Northcote, P. T.; Berridge, M. V.; Wakefield, S. J.; Miller, J. H. Cancer Res. 2002, 62, 3356.
3. (a) Gaitanos, T. N.; Buey, R. M.; Diaz, J. F.; Northcote, P. T.; Teesdale-Spittle, P.; Andreu, J. M.; Miller, J. H. Cancer Res. 2004, 64, 5063.
4. (b) Miller, J. H.; Rouwe, B.; Gaitanos, T. N.; Hood, K. A.; Crume, K. P.; Backstrom, B. T.; La Flamme, A. C.; Berridge, M. V.; Northcote, P. T. Apoptosis 2004, 9, 785.
5. Liao, X.; Wu, Y.; De Brabander, J. K. Angew. Chem., Int. Ed. 2003, 42, 1648.
6. For additional synthetic efforts towards peloruside A see ref 6 and (a) Cox, J. M.; Furichi, N.; Kenesky, C. S.; Zheng, J. Y.; Smith A. B. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-378. (b) Jin, M. Z.; Nicholson, C.; Taylor, R. E. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-382. (c) Owen, R. M.; Roush, W. R. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-707. (d) Vergin, A. J. B.; Ryba, T. D. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; CHED-494. (e) Engers, D. W.; Bassindale, M. J.; Pagenkopf, B. L. Org. Lett. 2004, 6, 663-666. (f) Stocker, B. L.; Teesdale-Spittle, P.; Hoberg, J. O. Eur. J. Org. Chem. 2004, 330-336. (g) Gurjar, M. K.; Pedduri, Y.; Ramana, C. V.; Puranik, V. G.; Gonnade, R. G. Tetrahedron Lett. 2004, 45, 387-390. (h) Liu, B.; Zhou, W. S. Org. Lett. 2004, 6, 71-74. (i) Ghosh, A. K.; Kim, J. H. Tetrahedron Lett. 2003, 44, 7659-7661. (j) Heady, T. N.; Crimmins, M. T. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; ORGN-408. (k) Paterson, I.; Di Francesco, M. E. and Kuhn, T. Org. Lett. 2003, 5, 599. (l) Ghosh, A. K.; Kim, J.-H. Tetrahedron Lett. 2003, 44, 3967. (m) Hoye, T. R.; Hu, M. 38th National Organic Chemistry Symposium, Bloomington, IN, June 8-12, 2003, Abstract A22.
7. For additional synthetic efforts towards peloruside A see ref 6 and (a) Cox, J. M.; Furichi, N.; Kenesky, C. S.; Zheng, J. Y.; Smith A. B. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-378. (b) Jin, M. Z.; Nicholson, C.; Taylor, R. E. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-382. (c) Owen, R. M.; Roush, W. R. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-707. (d) Vergin, A. J. B.; Ryba, T. D. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; CHED-494. (e) Engers, D. W.; Bassindale, M. J.; Pagenkopf, B. L. Org. Lett. 2004, 6, 663-666. (f) Stocker, B. L.; Teesdale-Spittle, P.; Hoberg, J. O. Eur. J. Org. Chem. 2004, 330-336. (g) Gurjar, M. K.; Pedduri, Y.; Ramana, C. V.; Puranik, V. G.; Gonnade, R. G. Tetrahedron Lett. 2004, 45, 387-390. (h) Liu, B.; Zhou, W. S. Org. Lett. 2004, 6, 71-74. (i) Ghosh, A. K.; Kim, J. H. Tetrahedron Lett. 2003, 44, 7659-7661. (j) Heady, T. N.; Crimmins, M. T. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; ORGN-408. (k) Paterson, I.; Di Francesco, M. E. and Kuhn, T. Org. Lett. 2003, 5, 599. (l) Ghosh, A. K.; Kim, J.-H. Tetrahedron Lett. 2003, 44, 3967. (m) Hoye, T. R.; Hu, M. 38th National Organic Chemistry Symposium, Bloomington, IN, June 8-12, 2003, Abstract A22.
8. For additional synthetic efforts towards peloruside A see ref 6 and (a) Cox, J. M.; Furichi, N.; Kenesky, C. S.; Zheng, J. Y.; Smith A. B. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-378. (b) Jin, M. Z.; Nicholson, C.; Taylor, R. E. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-382. (c) Owen, R. M.; Roush, W. R. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-707. (d) Vergin, A. J. B.; Ryba, T. D. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; CHED-494. (e) Engers, D. W.; Bassindale, M. J.; Pagenkopf, B. L. Org. Lett. 2004, 6, 663-666. (f) Stocker, B. L.; Teesdale-Spittle, P.; Hoberg, J. O. Eur. J. Org. Chem. 2004, 330-336. (g) Gurjar, M. K.; Pedduri, Y.; Ramana, C. V.; Puranik, V. G.; Gonnade, R. G. Tetrahedron Lett. 2004, 45, 387-390. (h) Liu, B.; Zhou, W. S. Org. Lett. 2004, 6, 71-74. (i) Ghosh, A. K.; Kim, J. H. Tetrahedron Lett. 2003, 44, 7659-7661. (j) Heady, T. N.; Crimmins, M. T. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; ORGN-408. (k) Paterson, I.; Di Francesco, M. E. and Kuhn, T. Org. Lett. 2003, 5, 599. (l) Ghosh, A. K.; Kim, J.-H. Tetrahedron Lett. 2003, 44, 3967. (m) Hoye, T. R.; Hu, M. 38th National Organic Chemistry Symposium, Bloomington, IN, June 8-12, 2003, Abstract A22.
9. For additional synthetic efforts towards peloruside A see ref 6 and (a) Cox, J. M.; Furichi, N.; Kenesky, C. S.; Zheng, J. Y.; Smith A. B. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-378. (b) Jin, M. Z.; Nicholson, C.; Taylor, R. E. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-382. (c) Owen, R. M.; Roush, W. R. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-707. (d) Vergin, A. J. B.; Ryba, T. D. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; CHED-494. (e) Engers, D. W.; Bassindale, M. J.; Pagenkopf, B. L. Org. Lett. 2004, 6, 663-666. (f) Stocker, B. L.; Teesdale-Spittle, P.; Hoberg, J. O. Eur. J. Org. Chem. 2004, 330-336. (g) Gurjar, M. K.; Pedduri, Y.; Ramana, C. V.; Puranik, V. G.; Gonnade, R. G. Tetrahedron Lett. 2004, 45, 387-390. (h) Liu, B.; Zhou, W. S. Org. Lett. 2004, 6, 71-74. (i) Ghosh, A. K.; Kim, J. H. Tetrahedron Lett. 2003, 44, 7659-7661. (j) Heady, T. N.; Crimmins, M. T. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; ORGN-408. (k) Paterson, I.; Di Francesco, M. E. and Kuhn, T. Org. Lett. 2003, 5, 599. (l) Ghosh, A. K.; Kim, J.-H. Tetrahedron Lett. 2003, 44, 3967. (m) Hoye, T. R.; Hu, M. 38th National Organic Chemistry Symposium, Bloomington, IN, June 8-12, 2003, Abstract A22.
10. For additional synthetic efforts towards peloruside A see ref 6 and (a) Cox, J. M.; Furichi, N.; Kenesky, C. S.; Zheng, J. Y.; Smith A. B. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-378. (b) Jin, M. Z.; Nicholson, C.; Taylor, R. E. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-382. (c) Owen, R. M.; Roush, W. R. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-707. (d) Vergin, A. J. B.; Ryba, T. D. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; CHED-494. (e) Engers, D. W.; Bassindale, M. J.; Pagenkopf, B. L. Org. Lett. 2004, 6, 663-666. (f) Stocker, B. L.; Teesdale-Spittle, P.; Hoberg, J. O. Eur. J. Org. Chem. 2004, 330-336. (g) Gurjar, M. K.; Pedduri, Y.; Ramana, C. V.; Puranik, V. G.; Gonnade, R. G. Tetrahedron Lett. 2004, 45, 387-390. (h) Liu, B.; Zhou, W. S. Org. Lett. 2004, 6, 71-74. (i) Ghosh, A. K.; Kim, J. H. Tetrahedron Lett. 2003, 44, 7659-7661. (j) Heady, T. N.; Crimmins, M. T. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; ORGN-408. (k) Paterson, I.; Di Francesco, M. E. and Kuhn, T. Org. Lett. 2003, 5, 599. (l) Ghosh, A. K.; Kim, J.-H. Tetrahedron Lett. 2003, 44, 3967. (m) Hoye, T. R.; Hu, M. 38th National Organic Chemistry Symposium, Bloomington, IN, June 8-12, 2003, Abstract A22.
11. For additional synthetic efforts towards peloruside A see ref 6 and (a) Cox, J. M.; Furichi, N.; Kenesky, C. S.; Zheng, J. Y.; Smith A. B. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-378. (b) Jin, M. Z.; Nicholson, C.; Taylor, R. E. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-382. (c) Owen, R. M.; Roush, W. R. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-707. (d) Vergin, A. J. B.; Ryba, T. D. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; CHED-494. (e) Engers, D. W.; Bassindale, M. J.; Pagenkopf, B. L. Org. Lett. 2004, 6, 663-666. (f) Stocker, B. L.; Teesdale-Spittle, P.; Hoberg, J. O. Eur. J. Org. Chem. 2004, 330-336. (g) Gurjar, M. K.; Pedduri, Y.; Ramana, C. V.; Puranik, V. G.; Gonnade, R. G. Tetrahedron Lett. 2004, 45, 387-390. (h) Liu, B.; Zhou, W. S. Org. Lett. 2004, 6, 71-74. (i) Ghosh, A. K.; Kim, J. H. Tetrahedron Lett. 2003, 44, 7659-7661. (j) Heady, T. N.; Crimmins, M. T. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; ORGN-408. (k) Paterson, I.; Di Francesco, M. E. and Kuhn, T. Org. Lett. 2003, 5, 599. (l) Ghosh, A. K.; Kim, J.-H. Tetrahedron Lett. 2003, 44, 3967. (m) Hoye, T. R.; Hu, M. 38th National Organic Chemistry Symposium, Bloomington, IN, June 8-12, 2003, Abstract A22.
12. For additional synthetic efforts towards peloruside A see ref 6 and (a) Cox, J. M.; Furichi, N.; Kenesky, C. S.; Zheng, J. Y.; Smith A. B. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-378. (b) Jin, M. Z.; Nicholson, C.; Taylor, R. E. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-382. (c) Owen, R. M.; Roush, W. R. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-707. (d) Vergin, A. J. B.; Ryba, T. D. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; CHED-494. (e) Engers, D. W.; Bassindale, M. J.; Pagenkopf, B. L. Org. Lett. 2004, 6, 663-666. (f) Stocker, B. L.; Teesdale-Spittle, P.; Hoberg, J. O. Eur. J. Org. Chem. 2004, 330-336. (g) Gurjar, M. K.; Pedduri, Y.; Ramana, C. V.; Puranik, V. G.; Gonnade, R. G. Tetrahedron Lett. 2004, 45, 387-390. (h) Liu, B.; Zhou, W. S. Org. Lett. 2004, 6, 71-74. (i) Ghosh, A. K.; Kim, J. H. Tetrahedron Lett. 2003, 44, 7659-7661. (j) Heady, T. N.; Crimmins, M. T. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; ORGN-408. (k) Paterson, I.; Di Francesco, M. E. and Kuhn, T. Org. Lett. 2003, 5, 599. (l) Ghosh, A. K.; Kim, J.-H. Tetrahedron Lett. 2003, 44, 3967. (m) Hoye, T. R.; Hu, M. 38th National Organic Chemistry Symposium, Bloomington, IN, June 8-12, 2003, Abstract A22.
13. For additional synthetic efforts towards peloruside A see ref 6 and (a) Cox, J. M.; Furichi, N.; Kenesky, C. S.; Zheng, J. Y.; Smith A. B. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-378. (b) Jin, M. Z.; Nicholson, C.; Taylor, R. E. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-382. (c) Owen, R. M.; Roush, W. R. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-707. (d) Vergin, A. J. B.; Ryba, T. D. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; CHED-494. (e) Engers, D. W.; Bassindale, M. J.; Pagenkopf, B. L. Org. Lett. 2004, 6, 663-666. (f) Stocker, B. L.; Teesdale-Spittle, P.; Hoberg, J. O. Eur. J. Org. Chem. 2004, 330-336. (g) Gurjar, M. K.; Pedduri, Y.; Ramana, C. V.; Puranik, V. G.; Gonnade, R. G. Tetrahedron Lett. 2004, 45, 387-390. (h) Liu, B.; Zhou, W. S. Org. Lett. 2004, 6, 71-74. (i) Ghosh, A. K.; Kim, J. H. Tetrahedron Lett. 2003, 44, 7659-7661. (j) Heady, T. N.; Crimmins, M. T. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; ORGN-408. (k) Paterson, I.; Di Francesco, M. E. and Kuhn, T. Org. Lett. 2003, 5, 599. (l) Ghosh, A. K.; Kim, J.-H. Tetrahedron Lett. 2003, 44, 3967. (m) Hoye, T. R.; Hu, M. 38th National Organic Chemistry Symposium, Bloomington, IN, June 8-12, 2003, Abstract A22.
14. For additional synthetic efforts towards peloruside A see ref 6 and (a) Cox, J. M.; Furichi, N.; Kenesky, C. S.; Zheng, J. Y.; Smith A. B. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-378. (b) Jin, M. Z.; Nicholson, C.; Taylor, R. E. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-382. (c) Owen, R. M.; Roush, W. R. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-707. (d) Vergin, A. J. B.; Ryba, T. D. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; CHED-494. (e) Engers, D. W.; Bassindale, M. J.; Pagenkopf, B. L. Org. Lett. 2004, 6, 663-666. (f) Stocker, B. L.; Teesdale-Spittle, P.; Hoberg, J. O. Eur. J. Org. Chem. 2004, 330-336. (g) Gurjar, M. K.; Pedduri, Y.; Ramana, C. V.; Puranik, V. G.; Gonnade, R. G. Tetrahedron Lett. 2004, 45, 387-390. (h) Liu, B.; Zhou, W. S. Org. Lett. 2004, 6, 71-74. (i) Ghosh, A. K.; Kim, J. H. Tetrahedron Lett. 2003, 44, 7659-7661. (j) Heady, T. N.; Crimmins, M. T. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; ORGN-408. (k) Paterson, I.; Di Francesco, M. E. and Kuhn, T. Org. Lett. 2003, 5, 599. (l) Ghosh, A. K.; Kim, J.-H. Tetrahedron Lett. 2003, 44, 3967. (m) Hoye, T. R.; Hu, M. 38th National Organic Chemistry Symposium, Bloomington, IN, June 8-12, 2003, Abstract A22.
15. For additional synthetic efforts towards peloruside A see ref 6 and (a) Cox, J. M.; Furichi, N.; Kenesky, C. S.; Zheng, J. Y.; Smith A. B. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-378. (b) Jin, M. Z.; Nicholson, C.; Taylor, R. E. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-382. (c) Owen, R. M.; Roush, W. R. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-707. (d) Vergin, A. J. B.; Ryba, T. D. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; CHED-494. (e) Engers, D. W.; Bassindale, M. J.; Pagenkopf, B. L. Org. Lett. 2004, 6, 663-666. (f) Stocker, B. L.; Teesdale-Spittle, P.; Hoberg, J. O. Eur. J. Org. Chem. 2004, 330-336. (g) Gurjar, M. K.; Pedduri, Y.; Ramana, C. V.; Puranik, V. G.; Gonnade, R. G. Tetrahedron Lett. 2004, 45, 387-390. (h) Liu, B.; Zhou, W. S. Org. Lett. 2004, 6, 71-74. (i) Ghosh, A. K.; Kim, J. H. Tetrahedron Lett. 2003, 44, 7659-7661. (j) Heady, T. N.; Crimmins, M. T. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; ORGN-408. (k) Paterson, I.; Di Francesco, M. E. and Kuhn, T. Org. Lett. 2003, 5, 599. (l) Ghosh, A. K.; Kim, J.-H. Tetrahedron Lett. 2003, 44, 3967. (m) Hoye, T. R.; Hu, M. 38th National Organic Chemistry Symposium, Bloomington, IN, June 8-12, 2003, Abstract A22.
16. For additional synthetic efforts towards peloruside A see ref 6 and (a) Cox, J. M.; Furichi, N.; Kenesky, C. S.; Zheng, J. Y.; Smith A. B. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-378. (b) Jin, M. Z.; Nicholson, C.; Taylor, R. E. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-382. (c) Owen, R. M.; Roush, W. R. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-707. (d) Vergin, A. J. B.; Ryba, T. D. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; CHED-494. (e) Engers, D. W.; Bassindale, M. J.; Pagenkopf, B. L. Org. Lett. 2004, 6, 663-666. (f) Stocker, B. L.; Teesdale-Spittle, P.; Hoberg, J. O. Eur. J. Org. Chem. 2004, 330-336. (g) Gurjar, M. K.; Pedduri, Y.; Ramana, C. V.; Puranik, V. G.; Gonnade, R. G. Tetrahedron Lett. 2004, 45, 387-390. (h) Liu, B.; Zhou, W. S. Org. Lett. 2004, 6, 71-74. (i) Ghosh, A. K.; Kim, J. H. Tetrahedron Lett. 2003, 44, 7659-7661. (j) Heady, T. N.; Crimmins, M. T. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; ORGN-408. (k) Paterson, I.; Di Francesco, M. E. and Kuhn, T. Org. Lett. 2003, 5, 599. (l) Ghosh, A. K.; Kim, J.-H. Tetrahedron Lett. 2003, 44, 3967. (m) Hoye, T. R.; Hu, M. 38th National Organic Chemistry Symposium, Bloomington, IN, June 8-12, 2003, Abstract A22.
17. For additional synthetic efforts towards peloruside A see ref 6 and (a) Cox, J. M.; Furichi, N.; Kenesky, C. S.; Zheng, J. Y.; Smith A. B. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-378. (b) Jin, M. Z.; Nicholson, C.; Taylor, R. E. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-382. (c) Owen, R. M.; Roush, W. R. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-707. (d) Vergin, A. J. B.; Ryba, T. D. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; CHED-494. (e) Engers, D. W.; Bassindale, M. J.; Pagenkopf, B. L. Org. Lett. 2004, 6, 663-666. (f) Stocker, B. L.; Teesdale-Spittle, P.; Hoberg, J. O. Eur. J. Org. Chem. 2004, 330-336. (g) Gurjar, M. K.; Pedduri, Y.; Ramana, C. V.; Puranik, V. G.; Gonnade, R. G. Tetrahedron Lett. 2004, 45, 387-390. (h) Liu, B.; Zhou, W. S. Org. Lett. 2004, 6, 71-74. (i) Ghosh, A. K.; Kim, J. H. Tetrahedron Lett. 2003, 44, 7659-7661. (j) Heady, T. N.; Crimmins, M. T. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; ORGN-408. (k) Paterson, I.; Di Francesco, M. E. and Kuhn, T. Org. Lett. 2003, 5, 599. (l) Ghosh, A. K.; Kim, J.-H. Tetrahedron Lett. 2003, 44, 3967. (m) Hoye, T. R.; Hu, M. 38th National Organic Chemistry Symposium, Bloomington, IN, June 8-12, 2003, Abstract A22.
18. For additional synthetic efforts towards peloruside A see ref 6 and (a) Cox, J. M.; Furichi, N.; Kenesky, C. S.; Zheng, J. Y.; Smith A. B. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-378. (b) Jin, M. Z.; Nicholson, C.; Taylor, R. E. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-382. (c) Owen, R. M.; Roush, W. R. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, August 22-26, 2004; American Chemical Society: Washington, DC, 2004; ORGN-707. (d) Vergin, A. J. B.; Ryba, T. D. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; CHED-494. (e) Engers, D. W.; Bassindale, M. J.; Pagenkopf, B. L. Org. Lett. 2004, 6, 663-666. (f) Stocker, B. L.; Teesdale-Spittle, P.; Hoberg, J. O. Eur. J. Org. Chem. 2004, 330-336. (g) Gurjar, M. K.; Pedduri, Y.; Ramana, C. V.; Puranik, V. G.; Gonnade, R. G. Tetrahedron Lett. 2004, 45, 387-390. (h) Liu, B.; Zhou, W. S. Org. Lett. 2004, 6, 71-74. (i) Ghosh, A. K.; Kim, J. H. Tetrahedron Lett. 2003, 44, 7659-7661. (j) Heady, T. N.; Crimmins, M. T. Abstracts of Papers, 225th ACS National Meeting, New Orleans, March 23-27, 2003; American Chemical Society: Washington, DC, 2003; ORGN-408. (k) Paterson, I.; Di Francesco, M. E. and Kuhn, T. Org. Lett. 2003, 5, 599. (l) Ghosh, A. K.; Kim, J.-H. Tetrahedron Lett. 2003, 44, 3967. (m) Hoye, T. R.; Hu, M. 38th National Organic Chemistry Symposium, Bloomington, IN, June 8-12, 2003, Abstract A22.
19. Taylor, R. E.; Jin, M. Z. Org. Lett. 2003, 5, 4959.
20. Yokokawa, F.; Asano, T.; Shioiri, T. Tetrahedron 2001, 57, 6311.
21. (a) Jones, T. K.; Reamer, R. A.; Desmond, R.; Mills, S. G. J. Am. Chem. Soc. 1990, 112, 2998.
22. (b) Crimmins, M. T.; Emmitte, K. A.; Katz, J. D. Org. Lett. 2000, 2, 2165.
23. (a) Rychnovsky, S. D.; Skalitzky, D. J. Tetrahedron Lett. 1990, 31, 945.
24. (b) Evans, D. A.; Rieger, D. L.; Gage, J. R. Tetrahedron Lett. 1990, 31, 7099.
25. De Brabander, J. K. (UTSW) Personal communication; also see ref 4.
26. Dess, D. B., Martin, J. C. J. Org. Chem. 1983, 48, 4155.
27. Inanaga, J.; Hirata, K.; Saeki, H.; Kastuki, T.; Yamaguchi, M. Bull. Chem. Soc. Jpn. 1979, 52, 1989.
28. Luche, J. L.; Rodriguez-Hahn, L.; Crabbe, P. J. Chem. Soc., Chem. Commun. 1978, 601.