Simultaneous measurement of ionic current and fluorescence from single protein pores

Journal of the American Chemical Society

Volumn 131, Issue 5, 2009, Pages 1652-1653

  Heron, Andrew J ^a   Thompson, James R ^a   Cronin, Bríd ^a   Bayley, Hagan ^a   Wallace, Mark I ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

IONIZATION OF LIQUIDS; PROTEINS;

BI-LAYER; ELECTRICAL CURRENT; ELECTRICAL DETECTION; FLUORESCENCE SIGNALS; IONIC CURRENT; MEMBRANE CHANNELS; MEMBRANE PROTEINS; PROTEIN PORES; SIMULTANEOUS MEASUREMENT; SINGLE-CHANNEL; STRUCTURAL CHANGE; TOTAL CURRENT; WATER-IN-OIL;

FLUORESCENCE;

ALPHA HEMOLYSIN; CALCIUM CHANNEL; CYCLODEXTRIN; PROTEIN; 1,2-DIPHYTANOYLPHOSPHATIDYLCHOLINE; BACTERIAL TOXIN; BETA CYCLODEXTRIN DERIVATIVE; HEMOLYSIN; HYDROGEL; ION CHANNEL; LIPID BILAYER; PHOSPHATIDYLCHOLINE; STAPHYLOCOCCAL ALPHA-TOXIN; TRI-O-METHYL-BETA-CYCLODEXTRIN;

ARTICLE; FLUORESCENCE IMAGING; ION CURRENT; LIPID BILAYER; MEASUREMENT; MEMBRANE CHANNEL; MOLECULAR IMAGING; CHEMISTRY; ELECTRODE; FLUORESCENCE MICROSCOPY; HYDROGEL; METABOLISM; STATISTICS;

BACTERIAL TOXINS; BETA-CYCLODEXTRINS; ELECTRODES; HEMOLYSIN PROTEINS; HYDROGELS; ION CHANNELS; LIPID BILAYERS; MICROSCOPY, FLUORESCENCE; PHOSPHATIDYLCHOLINES; STOCHASTIC PROCESSES;

EID: 67849083467     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja808128s     Document Type: Article

References (22)

1. Bavlev, H.; Cronin, B.; Heron, A.; Holden, M.; Hwang, W.; Sveda, R.; Thompson, J.; Wallace, M, Mol. Biosyst. 2008, 4, 1191-1208.
2. Holden, M. A.; Needham, D,; Bavlev, H, J Am. Chem. Soc. 2007, 129, 8650-8655.
3. Heron. A. J.; Thompson, J. R.; Mason, A. E.; Wallace. M. I J Am. Chem. Soc. 2007, 129, 16042-16047.
4. Thompson. J. R.; Heron. A. J.: Santoso. Y.; Wallace. M. I. Nano Lett. 2007, 7, 3875-3878.
5. Sachs. J. N.; Engelman. D. M. Annu. Rev. Biochem. 2006, 75, 707-712.
6. Zheng, J.; Zagotta. W. Science's STKE 2003, 2003.
7. Macdonald. A. G.; Wraight. P. C, Prog. Biophys. Mol. Biol. 1995, 63, 1-29.
8. Bezanilla, F. Nat. Rev. Mol. Cell. Biol 2008, 9, 323-332.
9. http://www.nature.com/nature/focus/ionchannel/.
10. Biskup, C; Kusch. J.; Schulz, E.: Nache, V.; Sehwede, F.; Lehmann, F.; Hagen, V.; Benndorf, K. Nature 2007, 446, 440-443.
11. Loots, E.; Isacoff, E. Y. J Gen. Physiol. 1998, 112, 377-389.
12. Joo. C; Balci, H.; Ishitsuka, Y.; Buranachai, C; Ha, T. Annu. Rev. Biochem. 2008, 77, 51-76.
13. Demuro, A.; Parker, I. J Gen. Physiol. 2005, 126, 179-192.
14. Harms, G. S.; Cognet, L.; Lommerse, P. H. M.; Blab, G. A.; Kahr, H.; Gamsjager, R.; Spaink. H. P.; Soldatov, N. M.; Romanin, C; Schmidt, T. Biophys. J. 2001, 81, 2639-2646.
15. Zou. H.; Lifshitz, L, M.; Tuft, R. A.; Fogarty, K, E.; Singer, J. J. Proc. Natl. Acad. Sci. U.S.A. 2002, 99, 6404-6409.
16. Wang. S, Q.; Song. L. S,; Lakatta. E. G.; Cheng, H. P, Nature 2001, 410, 592-596,
17. Ide. T.; Yanaeida. T. Biochem. Biophys. Res. Commun. 1999, 265, 595- 599.
18. Harms, G. S.; Orr. G.; Montal, M.; Thrall. B. D.; Colson. S. D.; Lu, H. P. Biophys. J. 2003, 85, 1826-1838.
19. Borisenko. V.; Lougheed. T.; Hesse, J.; Fureder-Kitzmuller. E.: Fertig. N.; Behrends, J. C; Woollev, G. A.; Schutz, G. J. Biophys. J. 2003, 84, 612- 622.
20. Song, L. Z.; Hobaugh. M. R.: Shustak, C; Chelev, S.; Bavley, H.; Gouaux, J. E. Science 1996, 274, 1859-1866.
21. Gu. L, Q ; Braha. O.; Conlan, S,; Cheley, S,; Bavley. H. Nature 1999, 398, 686-690.
22. Karginov, V. A.; Nestorovich, E. M.; Schmidtmann, F.; Robinson, T. M.; Yohannes, A.; Fahmi, N. E.; Bezrukov. S. M.; Hecht, S. M. Bioorgan. Med. Chem. 2007, 15, 5424-5431.