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Volumn 16, Issue 7, 2009, Pages 827-829

New concepts for siRNA design: The beauty of asymmetry: Asymmetry in siRNA design

(1)  Grimm, D a  

a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARGONAUTE 2 PROTEIN; BETA CATENIN; DOUBLE STRANDED RNA; MESSENGER RNA; MICRORNA; SMALL INTERFERING RNA; SMALL INTERNALLY SEGMENTED INTERFERING RNA; UNCLASSIFIED DRUG; RNA INDUCED SILENCING COMPLEX;

EID: 67749129050     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2009.45     Document Type: Note
Times cited : (11)

References (10)
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    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
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    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 2
    • 33847036990 scopus 로고    scopus 로고
    • Strategies for silencing human disease using RNA interference
    • Kim DH, Rossi JJ. Strategies for silencing human disease using RNA interference. Nat Rev Gen 2007; 8: 173-184.
    • (2007) Nat Rev Gen , vol.8 , pp. 173-184
    • Kim, D.H.1    Rossi, J.J.2
  • 3
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001; 411: 494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 4
    • 57349134691 scopus 로고    scopus 로고
    • Chemical modification of siRNAs for in vivo use
    • Behlke MA. Chemical modification of siRNAs for in vivo use. Oligonucleotides 2008; 18: 305-320.
    • (2008) Oligonucleotides , vol.18 , pp. 305-320
    • Behlke, M.A.1
  • 5
    • 33747761923 scopus 로고    scopus 로고
    • On the art of identifying effective and specific siRNAs
    • Pei Y, Tuschl T. On the art of identifying effective and specific siRNAs. Nat Meth 2006; 3: 670-676.
    • (2006) Nat Meth , vol.3 , pp. 670-676
    • Pei, Y.1    Tuschl, T.2
  • 6
    • 57449107290 scopus 로고    scopus 로고
    • Asymmetric RNA duplexes mediate RNA interference in mammalian cells
    • Sun X, Rogoff HA, Chiang JL. Asymmetric RNA duplexes mediate RNA interference in mammalian cells. Nat Biotechnol 2008; 26: 1379-1382.
    • (2008) Nat Biotechnol , vol.26 , pp. 1379-1382
    • Sun, X.1    Rogoff, H.A.2    Chiang, J.L.3
  • 7
    • 50649103008 scopus 로고    scopus 로고
    • Potent RNAi by short RNA triggers
    • Chu C-Y, Rana TM. Potent RNAi by short RNA triggers. RNA 2008; 14: 1714-1719.
    • (2008) RNA , vol.14 , pp. 1714-1719
    • Chu, C.-Y.1    Rana, T.M.2
  • 9
    • 33747777302 scopus 로고    scopus 로고
    • Gene silencing with siRNA duplexes composed of target-mNA-complementary and partially palindromic or partially complementary single-stranded siRNAs
    • Hossbach M, Gruber J, Osborn M, Weber K, Tuschl T. Gene silencing with siRNA duplexes composed of target-mNA-complementary and partially palindromic or partially complementary single-stranded siRNAs. RNA Biology 2006; 3: 82-89.
    • (2006) RNA Biology , vol.3 , pp. 82-89
    • Hossbach, M.1    Gruber, J.2    Osborn, M.3    Weber, K.4    Tuschl, T.5
  • 10
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    • Activation of the protein kinase PKR by short double-stranded RNAs with single-stranded tails
    • Zheng X, Bevilacqua PC. Activation of the protein kinase PKR by short double-stranded RNAs with single-stranded tails. RNA 2004; 10 1934-1945.
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    • Zheng, X.1    Bevilacqua, P.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.