Signaling pathways implicated in the stimulation of β-cell proliferation by extracellular matrix

Molecular Endocrinology

Volumn 23, Issue 8, 2009, Pages 1264-1271

  Parnaud, Géraldine ^a,b   Hammar, Eva ^a   Ribaux, Pascale ^a   Donath, Marc Y ^c   Berney, Thierry ^b   Halban, Philippe A ^a  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BELFOSDIL; CALCINEURIN; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIN D1; CYCLINE; CYCLOSPORIN A; DIAZOXIDE; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3BETA; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; KALININ; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; SB 20358; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL DIVISION; CELL GROWTH; CELL PROLIFERATION; CELL SPREADING; CELL SURVIVAL; CONTROLLED STUDY; ENZYME INHIBITION; EXTRACELLULAR MATRIX; GENE; GENE EXPRESSION; I KAPPA B ALPHA GENE; INSULIN RELEASE; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CALCIUM; CELL ADHESION MOLECULES; CELL PROLIFERATION; EXTRACELLULAR MATRIX; GLYCOGEN SYNTHASE KINASE 3; INSULIN-SECRETING CELLS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MAP KINASE SIGNALING SYSTEM; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

RATTUS;

EID: 67749101884     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2009-0008     Document Type: Article

References (52)

1. Roskelley CD, Srebrow A, Bissell MJ 1995 A hierarchy of ECM-mediated signalling regulates tissue-specific gene expression. Curr Opin Cell Biol 7:736-747
2. Lelièvre S, Weaver VM, Bissell MJ 1996 Extracellular matrix signaling from the cellular membrane skeleton to the nuclear skeleton: a model of gene regulation. Recent Prog Horm Res 51:417-432
3. Li S, Edgar D, Fässler R, Wadsworth W, Yurchenco PD 2003 The role of laminin in embryonic cell polarization and tissue organization. Dev Cell 4:613-624
4. Hisaoka M, Haratake J, Hashimoto H 1993 Pancreatic morphogenesis and extracellular matrix organization during rat development. Differentiation 53: 163-172
5. Boudreau NJ, Jones PL 1999 Extracellular matrix and integrin signalling: the shape of things to come. Biochem J 339(Pt 3):481-488
6. Hammar E, Parnaud G, Bosco D, Perriraz N, Maedler K, Donath M, Rouiller DG, Halban PA 2004 Extracellular matrix protects pancreatic β-cells against apoptosis: role of short- and long-term signaling pathways. Diabetes 53:2034-2041
7. Parnaud G, Bosco D, Berney T, Pattou F, Kerr-Conte J, Donath MY, Bruun C, Mandrup-Poulsen T, Billestrup N, Halban PA 2008 Proliferation of sorted human and rat β-cells. Diabetologia 51:91-100
8. Hammar EB, Irminger JC, Rickenbach K, Parnaud G, Ribaux P, Bosco D, Rouiller DG, Halban PA 2005 Activation of NF-κB by extracellular matrix is involved in spreading and glucose-stimulated insulin secretion of pancreatic β-cells. J Biol Chem 280:30630-30637
9. Ribaux P, Ehses JA, Lin-Marq N, Carrozzino F, Böni-Schnetzler M, Hammar E, Irminger JC, Donath MY, Halban PA 2007 Induction of CXCL1 by extracellular matrix and autocrine enhancement by interleukin-1 in rat pancreatic β-cells. Endocrinology 148:5582-5590
10. Böni-Schnetzler M, Thorne J, Parnaud G, Marselli L, Ehses JA, Kerr-Conte J, Pattou F, Halban PA, Weir GC, Donath MY 2008 Increased interleukin (IL)-1β messenger ribonucleic acid expression in β-cells of individuals with type 2 diabetes and regulation of IL-1β in human islets by glucose and autostimulation. J Clin Endocrinol Metab 93:4065-4074
11. Bosco D, Gonelle-Gispert C, Wollheim CB, Halban PA, Rouiller DG 2001 Increased intracellular calcium is required for spreading of rat islet β-cells on extracellular matrix. Diabetes 50:1039-1046
12. Whitaker M 2006 Calcium microdomains and cell cycle control. Cell Calcium 40:585-592
13. Heit JJ, Apelqvist AA, Gu X, WinslowMM,Neilson JR, Crabtree GR, Kim SK 2006 Calcineurin/NFAT signalling regulates pancreatic β-cell growth and function. Nature 443:345-349
14. Rao A, Luo C, Hogan PG 1997 Transcription factors of the NFAT family: regulation and function. Annu Rev Immunol 15:707-747
15. Adams JC, Watt FM 1993 Regulation of development and differentiation by the extracellular matrix. Development 117:1183-1198
16. Moldovan GL, Pfander B, Jentsch S 2007 PCNA, the maestro of the replication fork. Cell 129:665-679
17. Vasilijevic A, Buzadzic B, Korac A, Petrovic V, Jankovic A, Korac B 2007 Beneficial effects of L-arginine nitric oxide-producing pathway in rats treated with alloxan. J Physiol 584:921-933
18. Boonstra J 2003 Progression through the G1-phase of the on-going cell cycle. J Cell Biochem 90:244-252
19. Cozar-Castellano I, Fiaschi-Taesch N, Bigatel TA, Takane KK, Garcia-Ocaña A, Vasavada R, Stewart AF 2006 Molecular control of cell cycle progression in the pancreatic β-cell. Endocr Rev 27:356-370
20. Georgia S, Bhushan A 2004 β-Cell replication is the primary mechanism for maintaining postnatal β-cell mass. J Clin Invest 114:963-968
21. Kushner JA, Ciemerych MA, Sicinska E, Wartschow LM, Teta M, Long SY, Sicinski P, White MF 2005 Cyclins D2 and D1 are essential for postnatal pancreatic β-cell growth. Mol Cell Biol 25:3752-3762
22. Martín J, Hunt SL, Dubus P, Sotillo R, Néhmé- Pélluard F, Magnuson MA, Parlow AF, Malumbres M, Ortega S, Barbacid M 2003 Genetic rescue of Cdk4 null mice restores pancreatic β-cell proliferation but not homeostatic cell number. Oncogene 22:5261-5269
23. Friedrichsen BN, Neubauer N, Lee YC, Gram VK, Blume N, Petersen JS, Nielsen JH, Møldrup A 2006 Stimulation of pancreatic β-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways. J Endocrinol 188:481-492
24. Cozar-Castellano I, Takane KK, Bottino R, Balamurugan AN, Stewart AF 2004 Induction of β-cell proliferation and retinoblastoma protein phosphorylation in rat and human islets using adenovirus-mediated transfer of cyclindependent kinase-4 and cyclin D1. Diabetes 53:149-159
25. Chick WL, Lauris V, Flewelling JH, Andrews KA, Woodruff JM 1973 Effects of glucose on β-cells in pancreatic monolayer cultures. Endocrinology 92: 212-218
26. Bernard C, Thibault C, Berthault MF, Magnan C, Saulnier C, Portha B, Pralong WF, Pénicaud L, Ktorza A 1998 Pancreatic β-cell regeneration after 48-h glucose infusion in mildly diabetic rats is not correlated with functional improvement. Diabetes 47:1058-1065
27. Bonner-Weir S, Deery D, Leahy JL, Weir GC 1989 Compensatory growth of pancreatic β-cells in adult rats after short-term glucose infusion. Diabetes 38:49-53
28. Paris M, Bernard-Kargar C, Berthault MF, Bouwens L, Ktorza A 2003 Specific and combined effects of insulin and glucose on functional pancreatic β-cell mass in vivo in adult rats. Endocrinology 144:2717-2727
29. Muller D, Huang GC, Amiel S, Jones PM, Persaud SJ 2006 Identification of insulin signaling elements in human β-cells: autocrine regulation of insulin gene expression. Diabetes 55:2835-2842
30. 2+ influx in MIN6 insulinoma cells. Diabetes 51(Suppl 3):S484-S488
31. Heit JJ 2007 Calcineurin/NFAT signaling in the β-cell: from diabetes to new therapeutics. Bioessays 29:1011-1021
32. Fernandez AM, Fernandez S, Carrero P, Garcia-Garcia M, Torres-Aleman I 2007 Calcineurin in reactive astrocytes plays a key role in the interplay between proinflammatory and anti-inflammatory signals. J Neurosci 27:8745-8756
33. Fisher WG, Yang PC, Medikonduri RK, Jafri MS 2006 NFAT and NFκB activation in T lymphocytes: a model of differential activation of gene expression. Ann Biomed Eng 34:1712-1728
34. Joyce D, Albanese C, Steer J, Fu M, Bouzahzah B, Pestell RG 2001 NF-κB and cell-cycle regulation: the cyclin connection. Cytokine Growth Factor Rev 12:73-90
35. Obata H, Biro S, Arima N, Kaieda H, Kihara T, Eto H, Miyata M, Tanaka H 1996 NF-κB is induced in the nuclei of cultured rat aortic smooth muscle cells by stimulation of various growth factors. Biochem Biophys Res Commun 224:27-32
36. Maedler K, Schumann DM, Sauter N, Ellingsgaard H, Bosco D, Baertschiger R, Iwakura Y, Oberholzer J, Wollheim CB, Gauthier BR, Donath MY 2006 Low concentration of interleukin-1βinduces FLICE-inhibitory protein-mediated β-cell proliferation in human pancreatic islets. Diabetes 55:2713-2722
37. Parnaud G, Hammar E, Rouiller DG, Armanet M, Halban PA, Bosco D 2006 Blockade of β1 integrin-laminin-5 interaction affects spreading and insulin secretion of rat β-cells attached on extracellular matrix. Diabetes 55:1413-1420
38. Liu Z, Tanabe K, Bernal-Mizrachi E, Permutt MA 2008 Mice with β-cell overexpression of glycogen synthase kinase-3β have reduced β-cell mass and proliferation. Diabetologia 51:623-631
39. Mussmann R, Geese M, Harder F, Kegel S, Andag U, Lomow A, Burk U, Onichtchouk D, Dohrmann C, Austen M 2007 Inhibition of GSK3 promotes replication and survival of pancreatic β-cells. J Biol Chem 282:12030-12037
40. Doble BW, Woodgett JR 2003 GSK-3: tricks of the trade for a multi-tasking kinase. J Cell Sci 116:1175-1186
41. Bournat JC, Brown AM, Soler AP 2000 Wnt-1 dependent activation of the survival factor NF-κB in PC12 cells. J Neurosci Res 61:21-32
42. Chambard JC, Lefloch R, Pouysségur J, Lenormand P 2007 ERK implication in cell cycle regulation. Biochim Biophys Acta 1773:1299-1310
43. Katz M, Amit I, Yarden Y 2007 Regulation of MAPKs by growth factors and receptor tyrosine kinases. Biochim Biophys Acta 1773:1161-1176
44. Raman M, Chen W, Cobb MH 2007 Differential regulation and properties of MAPKs. Oncogene 26:3100-3112
45. Hong H, McCullough CM, Stegemann JP 2007 The role of ERK signaling in protein hydrogel remodeling by vascular smooth muscle cells. Biomaterials 28:3824-3833
46. Ambrosino C, Nebreda AR 2001 Cell cycle regulation by p38 MAP kinases. Biol Cell 93:47-51
47. Lavoie JN, L'Allemain G, Brunet A, Müller R, Pouysségur J 1996 Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway. J Biol Chem 271:20608-20616
48. Ellinger-Ziegelbauer H, Kelly K, Siebenlist U 1999 Cell cycle arrest and reversion of Ras-induced transformation by a conditionally activated form of mitogen-activated protein kinase kinase kinase 3. Mol Cell Biol 19:3857-3868
49. Engel FB, Schebesta M, Duong MT, Lu G, Ren S, Madwed JB, Jiang H, Wang Y, Keating MT 2005 p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes. Genes Dev 19:1175-1187
50. Rouiller DG, Cirulli V, Halban PA 1990 Differences in aggregation properties and levels of the neural cell adhesion molecule (NCAM) between islet cell types. Exp Cell Res 191:305-312
51. Bosco D, Meda P, Halban PA, Rouiller DG 2000 Importance of cell-matrix interactions in rat islet β-cell secretion in vitro: role of α6β1 integrin. Diabetes 49:233-243
52. Schaffner W, Weissmann C 1973 A rapid, sensitive, and specific method for the determination of protein in dilute solution. Anal Biochem 56:502-514