메뉴 건너뛰기




Volumn 4, Issue 7, 2009, Pages

IL-12 can target human lung adenocarcinoma cells and normal bronchial epithelial cells surrounding tumor lesions

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 12 RECEPTOR; INTERLEUKIN 12 RECEPTOR BETA2; INTERLEUKIN 6; KALININ; MONOCYTE CHEMOTACTIC PROTEIN 1; RECOMBINANT INTERLEUKIN 12; VASCULOTROPIN C; VASCULOTROPIN D; INTERLEUKIN 12;

EID: 67749101418     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006119     Document Type: Article
Times cited : (38)

References (45)
  • 1
    • 2942752374 scopus 로고    scopus 로고
    • The IL-12Rbeta2 gene functions as a tumor suppressor in human B cell malignancies
    • Airoldi I, Di Carlo E, Banelli B, Moserle L, Cocco C, et al. (2004) The IL-12Rbeta2 gene functions as a tumor suppressor in human B cell malignancies. J Clin Invest 113: 1651-1659.
    • (2004) J Clin Invest , vol.113 , pp. 1651-1659
    • Airoldi, I.1    Di Carlo, E.2    Banelli, B.3    Moserle, L.4    Cocco, C.5
  • 2
    • 0027239503 scopus 로고
    • Antitumor and antimetastatic activity of interleukin 12 against murine tumors
    • Brunda MJ, Luistro L, Warrier RR, Wright RB, Hubbard BR, et al. (1993) Antitumor and antimetastatic activity of interleukin 12 against murine tumors. J Exp Med 178: 1223-1230.
    • (1993) J Exp Med , vol.178 , pp. 1223-1230
    • Brunda, M.J.1    Luistro, L.2    Warrier, R.R.3    Wright, R.B.4    Hubbard, B.R.5
  • 3
    • 0036005890 scopus 로고    scopus 로고
    • Interleukin-12 in anti-tumor immunity and immunotherapy
    • Colombo MP, Trinchieri G (2002) Interleukin-12 in anti-tumor immunity and immunotherapy. Cytokine Growth Factor Rev 13: 155-168.
    • (2002) Cytokine Growth Factor Rev , vol.13 , pp. 155-168
    • Colombo, M.P.1    Trinchieri, G.2
  • 4
    • 0032578703 scopus 로고    scopus 로고
    • IL-12 regulates VEGF and MMPs in a murine breast cancer model
    • Dias S, Boyd R, Balkwill F (1998) IL-12 regulates VEGF and MMPs in a murine breast cancer model. Int J Cancer 78: 361-365.
    • (1998) Int J Cancer , vol.78 , pp. 361-365
    • Dias, S.1    Boyd, R.2    Balkwill, F.3
  • 5
    • 0029922177 scopus 로고    scopus 로고
    • Inhibition of angiogenesis by interleukin-12 is mediated by the interferon-inducible protein 10
    • Sgadari C, Angiolillo AL, Tosato G (1996) Inhibition of angiogenesis by interleukin-12 is mediated by the interferon-inducible protein 10. Blood 87: 3877-3882.
    • (1996) Blood , vol.87 , pp. 3877-3882
    • Sgadari, C.1    Angiolillo, A.L.2    Tosato, G.3
  • 7
    • 0034652459 scopus 로고    scopus 로고
    • Direct in vitro evidence and in vivo analysis of the antiangiogenesis effects of interleukin 12
    • Duda DG, Sunamura M, Lozonschi L, Kodama T, Egawa S, et al. (2000) Direct in vitro evidence and in vivo analysis of the antiangiogenesis effects of interleukin 12. Cancer Res 60: 1111-1116.
    • (2000) Cancer Res , vol.60 , pp. 1111-1116
    • Duda, D.G.1    Sunamura, M.2    Lozonschi, L.3    Kodama, T.4    Egawa, S.5
  • 8
    • 0030445948 scopus 로고    scopus 로고
    • A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits
    • Presky DH, Yang H, Minetti LJ, Chua AO, Nabavi N, et al. (1996) A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits. Proc Natl Acad Sci U S A 93: 14002-14007.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 14002-14007
    • Presky, D.H.1    Yang, H.2    Minetti, L.J.3    Chua, A.O.4    Nabavi, N.5
  • 9
    • 33646247193 scopus 로고    scopus 로고
    • Methylation of the IL-12Rbeta2 gene as novel tumor escape mechanism for pediatric B-acute lymphoblastic leukemia cells
    • Airoldi I, Cocco C, Di Carlo E, Disaro S, Ognio E, et al. (2006) Methylation of the IL-12Rbeta2 gene as novel tumor escape mechanism for pediatric B-acute lymphoblastic leukemia cells. Cancer Res 66: 3978-3980.
    • (2006) Cancer Res , vol.66 , pp. 3978-3980
    • Airoldi, I.1    Cocco, C.2    Di Carlo, E.3    Disaro, S.4    Ognio, E.5
  • 10
    • 28444443017 scopus 로고    scopus 로고
    • Lack of Il12rb2 signaling predisposes to spontaneous autoimmunity and malignancy
    • Airoldi I, Di Carlo E, Cocco C, Sorrentino C, Fais F, et al. (2005) Lack of Il12rb2 signaling predisposes to spontaneous autoimmunity and malignancy. Blood 106: 3846-3853.
    • (2005) Blood , vol.106 , pp. 3846-3853
    • Airoldi, I.1    Di Carlo, E.2    Cocco, C.3    Sorrentino, C.4    Fais, F.5
  • 11
    • 36849012237 scopus 로고    scopus 로고
    • Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas
    • Gao SP, Mark KG, Leslie K, Pao W, Motoi N, et al. (2007) Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas. J Clin Invest 117: 3846-3856.
    • (2007) J Clin Invest , vol.117 , pp. 3846-3856
    • Gao, S.P.1    Mark, K.G.2    Leslie, K.3    Pao, W.4    Motoi, N.5
  • 12
    • 17644368573 scopus 로고    scopus 로고
    • Interleukin-6: From basic science to medicine - 40 years in immunology
    • Kishimoto T (2005) Interleukin-6: from basic science to medicine - 40 years in immunology. Annu Rev Immunol 23: 1-21.
    • (2005) Annu Rev Immunol , vol.23 , pp. 1-21
    • Kishimoto, T.1
  • 13
    • 33746238953 scopus 로고    scopus 로고
    • Autocrine IL-6-induced Stat3 activation contributes to the pathogenesis of lung adenocarcinoma and malignant pleural effusion
    • Yeh HH, Lai WW, Chen HH, Liu HS, Su WC (2006) Autocrine IL-6-induced Stat3 activation contributes to the pathogenesis of lung adenocarcinoma and malignant pleural effusion. Oncogene 25: 4300-4309.
    • (2006) Oncogene , vol.25 , pp. 4300-4309
    • Yeh, H.H.1    Lai, W.W.2    Chen, H.H.3    Liu, H.S.4    Su, W.C.5
  • 16
    • 0033950286 scopus 로고    scopus 로고
    • Comparison of survival and quality of life in advanced non-small-cell lung cancer patients treated with two dose levels of paclitaxel combined with cisplatin versus etoposide with cisplatin: Results of an Eastern Cooperative Oncology Group trial
    • Bonomi P, Kim K, Fairclough D, Cella D, Kugler J, et al. (2000) Comparison of survival and quality of life in advanced non-small-cell lung cancer patients treated with two dose levels of paclitaxel combined with cisplatin versus etoposide with cisplatin: results of an Eastern Cooperative Oncology Group trial. J Clin Oncol 18: 623-631.
    • (2000) J Clin Oncol , vol.18 , pp. 623-631
    • Bonomi, P.1    Kim, K.2    Fairclough, D.3    Cella, D.4    Kugler, J.5
  • 20
    • 34548556471 scopus 로고    scopus 로고
    • Aberrant methylation of IL-12Rbeta2 gene in lung adenocarcinoma cells is associated with unfavorable prognosis
    • Suzuki M, Iizasa T, Nakajima T, Kubo R, Iyoda A, et al. (2007) Aberrant methylation of IL-12Rbeta2 gene in lung adenocarcinoma cells is associated with unfavorable prognosis. Ann Surg Oncol 14: 2636-2642.
    • (2007) Ann Surg Oncol , vol.14 , pp. 2636-2642
    • Suzuki, M.1    Iizasa, T.2    Nakajima, T.3    Kubo, R.4    Iyoda, A.5
  • 21
    • 2942677282 scopus 로고    scopus 로고
    • Crosstalk between angiogenesis and lymphangiogenesis in tumor progression
    • Scavelli C, Vacca A, Di Pietro G, Dammacco F, Ribatti D (2004) Crosstalk between angiogenesis and lymphangiogenesis in tumor progression. Leukemia 18: 1054-1058.
    • (2004) Leukemia , vol.18 , pp. 1054-1058
    • Scavelli, C.1    Vacca, A.2    Di Pietro, G.3    Dammacco, F.4    Ribatti, D.5
  • 22
    • 65549118866 scopus 로고    scopus 로고
    • Endothelin-1 stimulates lymphatic endothelial cells and lymphatic vessels to grow and invade
    • Spinella F, Garrafa E, Di Castro V, Rosano L, Nicotra MR, et al. (2009) Endothelin-1 stimulates lymphatic endothelial cells and lymphatic vessels to grow and invade. Cancer Res 69: 2669-2676.
    • (2009) Cancer Res , vol.69 , pp. 2669-2676
    • Spinella, F.1    Garrafa, E.2    Di Castro, V.3    Rosano, L.4    Nicotra, M.R.5
  • 23
    • 0032418043 scopus 로고    scopus 로고
    • An improved method to obtain highly differentiated monolayers of human bronchial epithelial cells
    • Galietta LJ, Lantero S, Gazzolo A, Sacco O, Romano L, et al. (1998) An improved method to obtain highly differentiated monolayers of human bronchial epithelial cells. In Vitro Cell Dev Biol Anim 34: 478-481.
    • (1998) In Vitro Cell Dev Biol Anim , vol.34 , pp. 478-481
    • Galietta, L.J.1    Lantero, S.2    Gazzolo, A.3    Sacco, O.4    Romano, L.5
  • 24
    • 4244175718 scopus 로고    scopus 로고
    • An electrogenic amino acid transporter in the apical membrane of cultured human bronchial epithelial cells
    • Galietta LJ, Musante L, Romio L, Caruso U, Fantasia A, et al. (1998) An electrogenic amino acid transporter in the apical membrane of cultured human bronchial epithelial cells. Am J Physiol 275: L917-923.
    • (1998) Am J Physiol , vol.275
    • Galietta, L.J.1    Musante, L.2    Romio, L.3    Caruso, U.4    Fantasia, A.5
  • 25
    • 0033946122 scopus 로고    scopus 로고
    • Modification of transepithelial ion transport in human cultured bronchial epithelial cells by interferon-gamma
    • Galietta LJ, Folli C, Marchetti C, Romano L, Carpani D, et al. (2000) Modification of transepithelial ion transport in human cultured bronchial epithelial cells by interferon-gamma. Am J Physiol Lung Cell Mol Physiol 278: L1186-1194.
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.278
    • Galietta, L.J.1    Folli, C.2    Marchetti, C.3    Romano, L.4    Carpani, D.5
  • 26
    • 0037080350 scopus 로고    scopus 로고
    • IL-4 is a potent modulator of ion transport in the human bronchial epithelium in vitro
    • Galietta LJ, Pagesy P, Folli C, Caci E, Romio L, et al. (2002) IL-4 is a potent modulator of ion transport in the human bronchial epithelium in vitro. J Immunol 168: 839-845.
    • (2002) J Immunol , vol.168 , pp. 839-845
    • Galietta, L.J.1    Pagesy, P.2    Folli, C.3    Caci, E.4    Romio, L.5
  • 27
    • 34848908049 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-C and its receptor VEGFR-3 in nonsmall-cell lung cancer: Concurrent expression in cancer cells from primary tumour and metastatic lymph node
    • Saintigny P, Kambouchner M, Ly M, Gomes N, Sainte-Catherine O, et al. (2007) Vascular endothelial growth factor-C and its receptor VEGFR-3 in nonsmall-cell lung cancer: concurrent expression in cancer cells from primary tumour and metastatic lymph node. Lung Cancer 58: 205-213.
    • (2007) Lung Cancer , vol.58 , pp. 205-213
    • Saintigny, P.1    Kambouchner, M.2    Ly, M.3    Gomes, N.4    Sainte-Catherine, O.5
  • 28
    • 33745550002 scopus 로고    scopus 로고
    • The balance of VEGF-C and VEGFR-3 mRNA is a predictor of lymph node metastasis in non-small cell lung cancer
    • Takizawa H, Kondo K, Fujino H, Kenzaki K, Miyoshi T, et al. (2006) The balance of VEGF-C and VEGFR-3 mRNA is a predictor of lymph node metastasis in non-small cell lung cancer. Br J Cancer 95: 75-79.
    • (2006) Br J Cancer , vol.95 , pp. 75-79
    • Takizawa, H.1    Kondo, K.2    Fujino, H.3    Kenzaki, K.4    Miyoshi, T.5
  • 29
    • 36849017497 scopus 로고    scopus 로고
    • IL-6 involvement in epithelial cancers
    • Schafer ZT, Brugge JS (2007) IL-6 involvement in epithelial cancers. J Clin Invest 117: 3660-3663.
    • (2007) J Clin Invest , vol.117 , pp. 3660-3663
    • Schafer, Z.T.1    Brugge, J.S.2
  • 30
    • 33846479526 scopus 로고    scopus 로고
    • IL-12 rapidly alters the functional profile of tumor-associated and tumor-infiltrating macrophages in vitro and in vivo
    • Watkins SK, Egilmez NK, Suttles J, Stout RD (2007) IL-12 rapidly alters the functional profile of tumor-associated and tumor-infiltrating macrophages in vitro and in vivo. J Immunol 178: 1357-1362.
    • (2007) J Immunol , vol.178 , pp. 1357-1362
    • Watkins, S.K.1    Egilmez, N.K.2    Suttles, J.3    Stout, R.D.4
  • 31
    • 0037314662 scopus 로고    scopus 로고
    • Up-regulation of tumor interleukin-8 expression by infiltrating macrophages: Its correlation with tumor angiogenesis and patient survival in non-small cell lung cancer
    • Chen JJ, Yao PL, Yuan A, Hong TM, Shun CT, et al. (2003) Up-regulation of tumor interleukin-8 expression by infiltrating macrophages: its correlation with tumor angiogenesis and patient survival in non-small cell lung cancer. Clin Cancer Res 9: 729-737.
    • (2003) Clin Cancer Res , vol.9 , pp. 729-737
    • Chen, J.J.1    Yao, P.L.2    Yuan, A.3    Hong, T.M.4    Shun, C.T.5
  • 32
    • 34250315638 scopus 로고    scopus 로고
    • The antibody-mediated targeted delivery of interleukin-15 and GM-CSF to the tumor neovasculature inhibits tumor growth and metastasis
    • Kaspar M, Trachsel E, Neri D (2007) The antibody-mediated targeted delivery of interleukin-15 and GM-CSF to the tumor neovasculature inhibits tumor growth and metastasis. Cancer Res 67: 4940-4948.
    • (2007) Cancer Res , vol.67 , pp. 4940-4948
    • Kaspar, M.1    Trachsel, E.2    Neri, D.3
  • 34
    • 39649103854 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony stimulating factor induces endothelial capillary formation through induction of membrane-type 1 matrix metalloproteinase expression in vitro
    • Krubasik D, Eisenach PA, Kunz-Schughart LA, Murphy G, English WR (2008) Granulocyte-macrophage colony stimulating factor induces endothelial capillary formation through induction of membrane-type 1 matrix metalloproteinase expression in vitro. Int J Cancer 122: 1261-1272.
    • (2008) Int J Cancer , vol.122 , pp. 1261-1272
    • Krubasik, D.1    Eisenach, P.A.2    Kunz-Schughart, L.A.3    Murphy, G.4    English, W.R.5
  • 35
    • 33847622522 scopus 로고    scopus 로고
    • Interleukin-8 stimulates cell proliferation in non-small cell lung cancer through epidermal growth factor receptor transactivation
    • Luppi F, Longo AM, de Boer WI, Rabe KF, Hiemstra PS (2007) Interleukin-8 stimulates cell proliferation in non-small cell lung cancer through epidermal growth factor receptor transactivation. Lung Cancer 56: 25-33.
    • (2007) Lung Cancer , vol.56 , pp. 25-33
    • Luppi, F.1    Longo, A.M.2    de Boer, W.I.3    Rabe, K.F.4    Hiemstra, P.S.5
  • 36
    • 11244328119 scopus 로고    scopus 로고
    • Interleukin-8/CXCL8 is a growth factor for human lung cancer cells
    • Zhu YM, Webster SJ, Flower D, Woll PJ (2004) Interleukin-8/CXCL8 is a growth factor for human lung cancer cells. Br J Cancer 91: 1970-1976.
    • (2004) Br J Cancer , vol.91 , pp. 1970-1976
    • Zhu, Y.M.1    Webster, S.J.2    Flower, D.3    Woll, P.J.4
  • 37
    • 33645991795 scopus 로고    scopus 로고
    • Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy
    • Sica A, Schioppa T, Mantovani A, Allavena P (2006) Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy. Eur J Cancer 42: 717-727.
    • (2006) Eur J Cancer , vol.42 , pp. 717-727
    • Sica, A.1    Schioppa, T.2    Mantovani, A.3    Allavena, P.4
  • 38
    • 34548118760 scopus 로고    scopus 로고
    • Use of a cytokine gene expression signature in lung adenocarcinoma and the surrounding tissue as a prognostic classifier
    • Seike M, Yanaihara N, Bowman ED, Zanetti KA, Budhu A, et al. (2007) Use of a cytokine gene expression signature in lung adenocarcinoma and the surrounding tissue as a prognostic classifier. J Natl Cancer Inst 99: 1257-1269.
    • (2007) J Natl Cancer Inst , vol.99 , pp. 1257-1269
    • Seike, M.1    Yanaihara, N.2    Bowman, E.D.3    Zanetti, K.A.4    Budhu, A.5
  • 39
    • 0036194917 scopus 로고    scopus 로고
    • Enhancement of the antitumor activity of interleukin-12 by targeted delivery to neovasculature
    • Halin C, Rondini S, Nilsson F, Berndt A, Kosmehl H, et al. (2002) Enhancement of the antitumor activity of interleukin-12 by targeted delivery to neovasculature. Nat Biotechnol 20: 264-269.
    • (2002) Nat Biotechnol , vol.20 , pp. 264-269
    • Halin, C.1    Rondini, S.2    Nilsson, F.3    Berndt, A.4    Kosmehl, H.5
  • 40
    • 0034103809 scopus 로고    scopus 로고
    • Phase I trial of twice-weekly intravenous interleukin 12 in patients with metastatic renal cell cancer or malignant melanoma: Ability to maintain IFN-gamma induction is associated with clinical response
    • Gollob JA, Mier JW, Veenstra K, McDermott DF, Clancy D, et al. (2000) Phase I trial of twice-weekly intravenous interleukin 12 in patients with metastatic renal cell cancer or malignant melanoma: ability to maintain IFN-gamma induction is associated with clinical response. Clin Cancer Res 6: 1678-1692.
    • (2000) Clin Cancer Res , vol.6 , pp. 1678-1692
    • Gollob, J.A.1    Mier, J.W.2    Veenstra, K.3    McDermott, D.F.4    Clancy, D.5
  • 41
    • 32044452015 scopus 로고    scopus 로고
    • IL-12 reverses anergy to T cell receptor triggering in human lung tumor-associated memory T cells
    • Broderick L, Brooks SP, Takita H, Baer AN, Bernstein JM, et al. (2006) IL-12 reverses anergy to T cell receptor triggering in human lung tumor-associated memory T cells. Clin Immunol 118: 159-169.
    • (2006) Clin Immunol , vol.118 , pp. 159-169
    • Broderick, L.1    Brooks, S.P.2    Takita, H.3    Baer, A.N.4    Bernstein, J.M.5
  • 43
    • 0017360990 scopus 로고
    • The measurement of observer agreement for categorical data
    • Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33: 159-174.
    • (1977) Biometrics , vol.33 , pp. 159-174
    • Landis, J.R.1    Koch, G.G.2
  • 44
    • 34250640742 scopus 로고    scopus 로고
    • The gelatin sponge-chorioallantoic membrane assay
    • Ribatti D, Nico B, Vacca A, Presta M (2006) The gelatin sponge-chorioallantoic membrane assay. Nat Protoc 1: 85-91.
    • (2006) Nat Protoc , vol.1 , pp. 85-91
    • Ribatti, D.1    Nico, B.2    Vacca, A.3    Presta, M.4
  • 45
    • 0031469270 scopus 로고    scopus 로고
    • New model for the study of angiogenesis and antiangiogenesis in the chick embryo chorioallantoic membrane: The gelatin sponge/ chorioallantoic membrane assay
    • Ribatti D, Gualandris A, Bastaki M, Vacca A, Iurlaro M, et al. (1997) New model for the study of angiogenesis and antiangiogenesis in the chick embryo chorioallantoic membrane: the gelatin sponge/ chorioallantoic membrane assay. J Vasc Res 34: 455-463.
    • (1997) J Vasc Res , vol.34 , pp. 455-463
    • Ribatti, D.1    Gualandris, A.2    Bastaki, M.3    Vacca, A.4    Iurlaro, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.