메뉴 건너뛰기




Volumn 10, Issue , 2009, Pages

Expression of HNF4alpha in the human and rat choroid plexus - Implications for drug transport across the blood-cerebrospinal-fluid (CSF) barrier

Author keywords

[No Author keywords available]

Indexed keywords

HEPATOCYTE NUCLEAR FACTOR 4ALPHA; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; MULTIDRUG RESISTANCE PROTEIN 5; MULTIDRUG RESISTANCE PROTEIN 6; PREALBUMIN; SMALL INTERFERING RNA; SOMATOMEDIN B; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXJ 1; UNCLASSIFIED DRUG; HEPATOCYTE NUCLEAR FACTOR 4; HNF4A PROTEIN, HUMAN; HNF4A PROTEIN, RAT;

EID: 67651225490     PISSN: None     EISSN: 14712199     Source Type: Journal    
DOI: 10.1186/1471-2199-10-68     Document Type: Article
Times cited : (25)

References (52)
  • 1
    • 0035157642 scopus 로고    scopus 로고
    • Brain drug delivery, drug metabolism, and multidrug resistance at the choroid plexus
    • 11135451
    • Ghersi-Egea JF Strazielle N Brain drug delivery, drug metabolism, and multidrug resistance at the choroid plexus Microsc Res Tech 2001, 52:83-88. 11135451
    • (2001) Microsc Res Tech , vol.52 , pp. 83-88
    • Ghersi-Egea, J.F.1    Strazielle, N.2
  • 2
    • 1442351170 scopus 로고    scopus 로고
    • Drug transport at the blood-brain barrier and the choroid plexus
    • 14965253
    • Graff CL Pollack GM Drug transport at the blood-brain barrier and the choroid plexus Curr Drug Metab 2004, 5:95-108. 14965253
    • (2004) Curr Drug Metab , vol.5 , pp. 95-108
    • Graff, C.L.1    Pollack, G.M.2
  • 3
    • 0037457802 scopus 로고    scopus 로고
    • Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: An overview
    • 12535572
    • Schinkel AH Jonker JW Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: An overview Adv Drug Deliv Rev 2003, 55:3-29. 12535572
    • (2003) Adv Drug Deliv Rev , vol.55 , pp. 3-29
    • Schinkel, A.H.1    Jonker, J.W.2
  • 4
    • 2542491777 scopus 로고    scopus 로고
    • The role of ABC transporters in drug resistance, metabolism and toxicity
    • 16305368
    • Glavinas H Krajcsi P Cserepes J Sarkadi B The role of ABC transporters in drug resistance, metabolism and toxicity Curr Drug Deliv 2004, 1:27-42. 16305368
    • (2004) Curr Drug Deliv , vol.1 , pp. 27-42
    • Glavinas, H.1    Krajcsi, P.2    Cserepes, J.3    Sarkadi, B.4
  • 5
    • 48749108121 scopus 로고    scopus 로고
    • MRP class of human ATP binding cassette (ABC) transporters: Historical background and new research directions
    • 18668432
    • Toyoda Y Hagiya Y Adachi T Hoshijima K Kuo MT Ishikawa T MRP class of human ATP binding cassette (ABC) transporters: Historical background and new research directions Xenobiotica 2008, 38:833-862. 18668432
    • (2008) Xenobiotica , vol.38 , pp. 833-862
    • Toyoda, Y.1    Hagiya, Y.2    Adachi, T.3    Hoshijima, K.4    Kuo, M.T.5    Ishikawa, T.6
  • 6
    • 0002772438 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4alpha
    • Academic Press, London Burris T, McCabe ERB
    • Sladek FM Seidel SD Hepatocyte nuclear factor 4alpha Nuclear Receptors and Disease Academic Press, London Burris T, McCabe ERB 2001:309-361.
    • (2001) Nuclear Receptors and Disease , pp. 309-361
    • Sladek, F.M.1    Seidel, S.D.2
  • 7
    • 0036200587 scopus 로고    scopus 로고
    • Liver-enriched transcription factors in liver function and development. Part I: The hepatocyte nuclear factor network and liver-specific gene expression
    • 11870262
    • Schrem H Klempnauer J Borlak J Liver-enriched transcription factors in liver function and development. Part I: The hepatocyte nuclear factor network and liver-specific gene expression Pharmacol Rev 2002, 54:129-158. 11870262
    • (2002) Pharmacol Rev , vol.54 , pp. 129-158
    • Schrem, H.1    Klempnauer, J.2    Borlak, J.3
  • 8
    • 0038757830 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis
    • 12808453
    • Parviz F Matullo C Garrison WD Savatski L Adamson JW Ning G et al Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis Nat Genet 2003, 34:292-296. 12808453
    • (2003) Nat Genet , vol.34 , pp. 292-296
    • Parviz, F.1    Matullo, C.2    Garrison, W.D.3    Savatski, L.4    Adamson, J.W.5    Ning, G.6
  • 9
    • 0035124052 scopus 로고    scopus 로고
    • Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: A study using adenovirus-mediated antisense targeting
    • 11230748
    • Jover R Bort R Gomez-Lechon MJ Castell JV Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: A study using adenovirus-mediated antisense targeting Hepatology 2001, 33:668-675. 11230748
    • (2001) Hepatology , vol.33 , pp. 668-675
    • Jover, R.1    Bort, R.2    Gomez-Lechon, M.J.3    Castell, J.V.4
  • 10
    • 42249106086 scopus 로고    scopus 로고
    • Regulation of hepatocyte nuclear factor 4 alpha-mediated transcription
    • 18305369
    • Gonzalez FJ Regulation of hepatocyte nuclear factor 4 alpha-mediated transcription Drug Metab Pharmacokinet 2008, 23:2-7. 18305369
    • (2008) Drug Metab Pharmacokinet , vol.23 , pp. 2-7
    • Gonzalez, F.J.1
  • 11
    • 19944428982 scopus 로고    scopus 로고
    • Hepatic expression of the UGT1A9 gene is governed by hepatocyte nuclear factor 4alpha
    • 15470081
    • Barbier O Girard H Inoue Y Duez H Villeneuve L Kamiya A et al Hepatic expression of the UGT1A9 gene is governed by hepatocyte nuclear factor 4alpha Mol Pharmacol 2005, 67:241-249. 15470081
    • (2005) Mol Pharmacol , vol.67 , pp. 241-249
    • Barbier, O.1    Girard, H.2    Inoue, Y.3    Duez, H.4    Villeneuve, L.5    Kamiya, A.6
  • 12
    • 34548301080 scopus 로고    scopus 로고
    • The xenobiotic-sensing nuclear receptors pregnane X receptor, constitutive androstane receptor, and orphan nuclear receptor hepatocyte nuclear factor 4alpha in the regulation of human steroid-/bile acid-sulfotransferase
    • 17595319
    • Echchgadda I Song CS Oh T Ahmed M De LCI Chatterjee B The xenobiotic-sensing nuclear receptors pregnane X receptor, constitutive androstane receptor, and orphan nuclear receptor hepatocyte nuclear factor 4alpha in the regulation of human steroid-/bile acid-sulfotransferase Mol Endocrinol 2007, 21:2099-2111. 17595319
    • (2007) Mol Endocrinol , vol.21 , pp. 2099-2111
    • Echchgadda, I.1    Song, C.S.2    Oh, T.3    Ahmed, M.4    De, L.C.I.5    Chatterjee, B.6
  • 13
    • 17844385785 scopus 로고    scopus 로고
    • The human organic anion transporter 2 gene is transactivated by hepatocyte nuclear factor-4{alpha} and suppressed by bile acids
    • 15692145
    • Popowski K Eloranta JJ Saborowski M Fried M Meier PJ Kullak-Ublick GA The human organic anion transporter 2 gene is transactivated by hepatocyte nuclear factor-4{alpha} and suppressed by bile acids Mol Pharmacol 2005, 67:1629-1638. 15692145
    • (2005) Mol Pharmacol , vol.67 , pp. 1629-1638
    • Popowski, K.1    Eloranta, J.J.2    Saborowski, M.3    Fried, M.4    Meier, P.J.5    Kullak-Ublick, G.A.6
  • 14
    • 33645870991 scopus 로고    scopus 로고
    • The Human Organic Cation Transporter 1 Gene is Transactivated by Hepatocyte Nuclear Factor-4{alpha}
    • 16436500
    • Saborowski M Kullak-Ublick GA Eloranta JJ The Human Organic Cation Transporter 1 Gene is Transactivated by Hepatocyte Nuclear Factor-4{alpha} J Pharmacol Exp Ther 2006, 317:778-785. 16436500
    • (2006) J Pharmacol Exp Ther , vol.317 , pp. 778-785
    • Saborowski, M.1    Kullak-Ublick, G.A.2    Eloranta, J.J.3
  • 15
    • 58649088927 scopus 로고    scopus 로고
    • Interaction of hepatocyte nuclear factors in transcriptional regulation of tissue specific hormonal expression of human multidrug resistance-associated protein 2 (abcc2)
    • 19010343
    • Qadri I Hu LJ Iwahashi M Al Zuabi S Quattrochi LC Simon FR Interaction of hepatocyte nuclear factors in transcriptional regulation of tissue specific hormonal expression of human multidrug resistance-associated protein 2 (abcc2) Toxicol Appl Pharmacol 2009, 234:281-292. 19010343
    • (2009) Toxicol Appl Pharmacol , vol.234 , pp. 281-292
    • Qadri, I.1    Hu, L.J.2    Iwahashi, M.3    Al Zuabi, S.4    Quattrochi, L.C.5    Simon, F.R.6
  • 16
    • 33749079860 scopus 로고    scopus 로고
    • HNF4alpha and NF-E2 are key transcriptional regulators of the murine Abcc6 gene expression
    • 1876778 16997394
    • Douet V VanWart CM Heller MB Reinhard S Le Saux O HNF4alpha and NF-E2 are key transcriptional regulators of the murine Abcc6 gene expression Biochim Biophys Acta 2006, 1759:426-436. 1876778 16997394
    • (2006) Biochim Biophys Acta , vol.1759 , pp. 426-436
    • Douet, V.1    VanWart, C.M.2    Heller, M.B.3    Reinhard, S.4    Le Saux, O.5
  • 17
    • 34250173805 scopus 로고    scopus 로고
    • Cooperative interaction between hepatocyte nuclear factor 4 alpha and GATA transcription factors regulates ATP-binding cassette sterol transporters ABCG5 and ABCG8
    • 1900057 17403900
    • Sumi K Tanaka T Uchida A Magoori K Urashima Y Ohashi R et al Cooperative interaction between hepatocyte nuclear factor 4 alpha and GATA transcription factors regulates ATP-binding cassette sterol transporters ABCG5 and ABCG8 Mol Cell Biol 2007, 27:4248-4260. 1900057 17403900
    • (2007) Mol Cell Biol , vol.27 , pp. 4248-4260
    • Sumi, K.1    Tanaka, T.2    Uchida, A.3    Magoori, K.4    Urashima, Y.5    Ohashi, R.6
  • 18
    • 0030967651 scopus 로고    scopus 로고
    • The winged helix transcription factor HFH-4 is expressed during choroid plexus epithelial development in the mouse embryo
    • 20327 9096351
    • Lim L Zhou H Costa RH The winged helix transcription factor HFH-4 is expressed during choroid plexus epithelial development in the mouse embryo Proc Natl Acad Sci USA 1997, 94:3094-3099. 20327 9096351
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3094-3099
    • Lim, L.1    Zhou, H.2    Costa, R.H.3
  • 19
    • 0033948974 scopus 로고    scopus 로고
    • Choroid plexus in the central nervous system: Biology and physiopathology
    • 10901227
    • Strazielle N Ghersi-Egea JF Choroid plexus in the central nervous system: Biology and physiopathology J Neuropathol Exp Neurol 2000, 59:561-574. 10901227
    • (2000) J Neuropathol Exp Neurol , vol.59 , pp. 561-574
    • Strazielle, N.1    Ghersi-Egea, J.F.2
  • 20
    • 0141884785 scopus 로고    scopus 로고
    • Expression of drug-metabolizing enzymes, nuclear transcription factors and ABC transporters in Caco-2 cells
    • 14514442
    • Borlak J Zwadlo C Expression of drug-metabolizing enzymes, nuclear transcription factors and ABC transporters in Caco-2 cells Xenobiotica 2003, 33:927-943. 14514442
    • (2003) Xenobiotica , vol.33 , pp. 927-943
    • Borlak, J.1    Zwadlo, C.2
  • 21
    • 14944361815 scopus 로고    scopus 로고
    • RSK4 and PAK5 Are Novel Candidate Genes in Diabetic Rat Kidney and Brain
    • 15615695
    • Niehof M Borlak J RSK4 and PAK5 Are Novel Candidate Genes in Diabetic Rat Kidney and Brain Mol Pharmacol 2005, 67:604-611. 15615695
    • (2005) Mol Pharmacol , vol.67 , pp. 604-611
    • Niehof, M.1    Borlak, J.2
  • 22
    • 42449109471 scopus 로고    scopus 로고
    • HNF4{alpha} and the Ca-Channel TRPC1 Are Novel Disease Candidate Genes in Diabetic Nephropathy
    • 18184923
    • Niehof M Borlak J HNF4{alpha} and the Ca-Channel TRPC1 Are Novel Disease Candidate Genes in Diabetic Nephropathy Diabetes 2008, 57:1069-1077. 18184923
    • (2008) Diabetes , vol.57 , pp. 1069-1077
    • Niehof, M.1    Borlak, J.2
  • 23
    • 0035141324 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis
    • 99591 11158324
    • Hayhurst GP Lee YH Lambert G Ward JM Gonzalez FJ Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis Mol Cell Biol 2001, 21:1393-1403. 99591 11158324
    • (2001) Mol Cell Biol , vol.21 , pp. 1393-1403
    • Hayhurst, G.P.1    Lee, Y.H.2    Lambert, G.3    Ward, J.M.4    Gonzalez, F.J.5
  • 24
  • 25
    • 0037621983 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor (HNF)-4alpha triggers formation of functional tight junctions and establishment of polarized epithelial morphology in F9 embryonal carcinoma cells
    • 12749857
    • Chiba H Gotoh T Kojima T Satohisa S Kikuchi K Osanai M et al Hepatocyte nuclear factor (HNF)-4alpha triggers formation of functional tight junctions and establishment of polarized epithelial morphology in F9 embryonal carcinoma cells Exp Cell Res 2003, 286:288-297. 12749857
    • (2003) Exp Cell Res , vol.286 , pp. 288-297
    • Chiba, H.1    Gotoh, T.2    Kojima, T.3    Satohisa, S.4    Kikuchi, K.5    Osanai, M.6
  • 26
    • 8344221886 scopus 로고    scopus 로고
    • Activation of p21(CIP1/WAF1) gene expression and inhibition of cell proliferation by overexpression of hepatocyte nuclear factor-4alpha
    • 15541721
    • Chiba H Itoh T Satohisa S Sakai N Noguchi H Osanai M et al Activation of p21(CIP1/WAF1) gene expression and inhibition of cell proliferation by overexpression of hepatocyte nuclear factor-4alpha Exp Cell Res 2005, 302:11-21. 15541721
    • (2005) Exp Cell Res , vol.302 , pp. 11-21
    • Chiba, H.1    Itoh, T.2    Satohisa, S.3    Sakai, N.4    Noguchi, H.5    Osanai, M.6
  • 27
    • 33744795211 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver
    • 1482507 16714383
    • Battle MA Konopka G Parviz F Gaggl AL Yang C Sladek FM et al Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver Proc Natl Acad Sci USA 2006, 103:8419-8424. 1482507 16714383
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 8419-8424
    • Battle, M.A.1    Konopka, G.2    Parviz, F.3    Gaggl, A.L.4    Yang, C.5    Sladek, F.M.6
  • 28
    • 0034747205 scopus 로고    scopus 로고
    • Expression of HNF4alpha isoforms in mouse liver development is regulated by sequential promoter usage and constitutive 3' end splicing
    • 11731232
    • Torres-Padilla ME Fougere-Deschatrette C Weiss MC Expression of HNF4alpha isoforms in mouse liver development is regulated by sequential promoter usage and constitutive 3' end splicing Mech Dev 2001, 109:183-193. 11731232
    • (2001) Mech Dev , vol.109 , pp. 183-193
    • Torres-Padilla, M.E.1    Fougere-Deschatrette, C.2    Weiss, M.C.3
  • 29
    • 41349084350 scopus 로고    scopus 로고
    • EPS15R, TASP1, and PRPF3 are novel disease candidate genes targeted by HNF4alpha splice variants in hepatocellular carcinomas
    • 18395097
    • Niehof M Borlak J EPS15R, TASP1, and PRPF3 are novel disease candidate genes targeted by HNF4alpha splice variants in hepatocellular carcinomas Gastroenterology 2008, 134:1191-1202. 18395097
    • (2008) Gastroenterology , vol.134 , pp. 1191-1202
    • Niehof, M.1    Borlak, J.2
  • 30
    • 33645215441 scopus 로고    scopus 로고
    • Dysregulated expression of P1 and P2 promoter-driven hepatocyte nuclear factor-4alpha in the pathogenesis of human cancer
    • 16400631
    • Tanaka T Jiang S Hotta H Takano K Iwanari H Sumi K et al Dysregulated expression of P1 and P2 promoter-driven hepatocyte nuclear factor-4alpha in the pathogenesis of human cancer J Pathol 2006, 208:662-672. 16400631
    • (2006) J Pathol , vol.208 , pp. 662-672
    • Tanaka, T.1    Jiang, S.2    Hotta, H.3    Takano, K.4    Iwanari, H.5    Sumi, K.6
  • 31
    • 0036736817 scopus 로고    scopus 로고
    • Genetic evidence that HNF-1{alpha}-dependent transcriptional control of HNF-4{alpha} is essential for human pancreatic {beta} cell function
    • 151122 12235114
    • Hansen SK Parrizas M Jensen ML Pruhova S Ek J et al Genetic evidence that HNF-1{alpha}-dependent transcriptional control of HNF-4{alpha} is essential for human pancreatic {beta} cell function J Clin Invest 2002, 110:827-833. 151122 12235114
    • (2002) J Clin Invest , vol.110 , pp. 827-833
    • Hansen, S.K.1    Parrizas, M.2    Jensen, M.L.3    Pruhova, S.4    Ek, J.5
  • 32
    • 0025054242 scopus 로고
    • Similarities in transthyretin gene expression and differences in transcription factors: Liver and yolk sac compared to choroid plexus
    • 54582 2395861
    • Costa RH Van Dyke TA Yan C Kuo F Darnell JE Jr Similarities in transthyretin gene expression and differences in transcription factors: liver and yolk sac compared to choroid plexus Proc Natl Acad Sci USA 1990, 87:6589-6593. 54582 2395861
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6589-6593
    • Costa, R.H.1    Van Dyke, T.A.2    Yan, C.3    Kuo, F.4    Darnell Jr., J.E.5
  • 33
    • 27144512719 scopus 로고    scopus 로고
    • HNF4alpha reduces proliferation of kidney cells and affects genes deregulated in renal cell carcinoma
    • 16007190
    • Lucas B Grigo K Erdmann S Lausen J Klein-Hitpass L Ryffel GU HNF4alpha reduces proliferation of kidney cells and affects genes deregulated in renal cell carcinoma Oncogene 2005, 24:6418-6431. 16007190
    • (2005) Oncogene , vol.24 , pp. 6418-6431
    • Lucas, B.1    Grigo, K.2    Erdmann, S.3    Lausen, J.4    Klein-Hitpass, L.5    Ryffel, G.U.6
  • 34
  • 35
    • 0036128985 scopus 로고    scopus 로고
    • Role of multidrug transporters in pharmacoresistance to antiepileptic drugs
    • 11907151
    • Loscher W Potschka H Role of multidrug transporters in pharmacoresistance to antiepileptic drugs J Pharmacol Exp Ther 2002, 301:7-14. 11907151
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 7-14
    • Loscher, W.1    Potschka, H.2
  • 36
    • 0037665280 scopus 로고    scopus 로고
    • Multidrug resistance protein MRP2 contributes to blood-brain barrier function and restricts antiepileptic drug activity
    • 12663688
    • Potschka H Fedrowitz M Loscher W Multidrug resistance protein MRP2 contributes to blood-brain barrier function and restricts antiepileptic drug activity J Pharmacol Exp Ther 2003, 306:124-131. 12663688
    • (2003) J Pharmacol Exp Ther , vol.306 , pp. 124-131
    • Potschka, H.1    Fedrowitz, M.2    Loscher, W.3
  • 37
    • 1642579542 scopus 로고    scopus 로고
    • Variable modulation of opioid brain uptake by P-glycoprotein in mice
    • 14698039
    • Dagenais C Graff CL Pollack GM Variable modulation of opioid brain uptake by P-glycoprotein in mice Biochem Pharmacol 2004, 67:269-276. 14698039
    • (2004) Biochem Pharmacol , vol.67 , pp. 269-276
    • Dagenais, C.1    Graff, C.L.2    Pollack, G.M.3
  • 38
    • 4344701123 scopus 로고    scopus 로고
    • Identification of P-glycoprotein substrates and inhibitors among psychoactive compounds-implications for pharmacokinetics of selected substrates
    • 15285840
    • El Ela AA Hartter S Schmitt U Hiemke C Spahn-Langguth H Langguth P Identification of P-glycoprotein substrates and inhibitors among psychoactive compounds-implications for pharmacokinetics of selected substrates J Pharm Pharmacol 2004, 56:967-975. 15285840
    • (2004) J Pharm Pharmacol , vol.56 , pp. 967-975
    • El Ela, A.A.1    Hartter, S.2    Schmitt, U.3    Hiemke, C.4    Spahn-Langguth, H.5    Langguth, P.6
  • 39
    • 19944425121 scopus 로고    scopus 로고
    • The impact of P-glycoprotein on the disposition of drugs targeted for indications of the central nervous system: Evaluation using the MDR1A/1B knockout mouse model
    • 15502009
    • Doran A Obach RS Smith BJ Hosea NA Becker S Callegari E et al The impact of P-glycoprotein on the disposition of drugs targeted for indications of the central nervous system: Evaluation using the MDR1A/1B knockout mouse model Drug Metab Dispos 2005, 33:165-174. 15502009
    • (2005) Drug Metab Dispos , vol.33 , pp. 165-174
    • Doran, A.1    Obach, R.S.2    Smith, B.J.3    Hosea, N.A.4    Becker, S.5    Callegari, E.6
  • 40
    • 43149118341 scopus 로고    scopus 로고
    • The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox)
    • 18468555
    • Szakacs G Varadi A Ozvegy-Laczka C Sarkadi B The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox) Drug Discov Today 2008, 13:379-393. 18468555
    • (2008) Drug Discov Today , vol.13 , pp. 379-393
    • Szakacs, G.1    Varadi, A.2    Ozvegy-Laczka, C.3    Sarkadi, B.4
  • 42
    • 0142212154 scopus 로고    scopus 로고
    • Constitutive expression of various xenobiotic and endobiotic transporter mRNAs in the choroid plexus of rats
    • 14570765
    • Choudhuri S Cherrington NJ Li N Klaassen CD Constitutive expression of various xenobiotic and endobiotic transporter mRNAs in the choroid plexus of rats Drug Metab Dispos 2003, 31:1337-1345. 14570765
    • (2003) Drug Metab Dispos , vol.31 , pp. 1337-1345
    • Choudhuri, S.1    Cherrington, N.J.2    Li, N.3    Klaassen, C.D.4
  • 43
    • 0033616684 scopus 로고    scopus 로고
    • Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier
    • 22392 10097135
    • Rao VV Dahlheimer JL Bardgett ME Snyder AZ Finch RA Sartorelli AC et al Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier Proc Natl Acad Sci USA 1999, 96:3900-3905. 22392 10097135
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 3900-3905
    • Rao, V.V.1    Dahlheimer, J.L.2    Bardgett, M.E.3    Snyder, A.Z.4    Finch, R.A.5    Sartorelli, A.C.6
  • 44
    • 0034604707 scopus 로고    scopus 로고
    • MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping
    • 10918072
    • Smith AJ van Helvoort A van Meer G Szabo K Welker E Szakacs G et al MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping J Biol Chem 2000, 275:23530-23539. 10918072
    • (2000) J Biol Chem , vol.275 , pp. 23530-23539
    • Smith, A.J.1    van Helvoort, A.2    van Meer, G.3    Szabo, K.4    Welker, E.5    Szakacs, G.6
  • 45
    • 0033975098 scopus 로고    scopus 로고
    • Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier
    • 377447 10675353
    • Wijnholds J deLange EC Scheffer GL Berg van den DJ Mol CA van d V et al Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier J Clin Invest 2000, 105:279-285. 377447 10675353
    • (2000) J Clin Invest , vol.105 , pp. 279-285
    • Wijnholds, J.1    deLange, E.C.2    Scheffer, G.L.3    Berg, D.J.4    Mol, C.A.5    van d, V.6
  • 46
    • 53149117869 scopus 로고    scopus 로고
    • Differential expression of the multidrug resistance-related proteins ABCb1 and ABCc1 between blood-brain interfaces
    • 18680196
    • Gazzin S Strazielle N Schmitt C Fevre-Montange M Ostrow JD Tiribelli C et al Differential expression of the multidrug resistance-related proteins ABCb1 and ABCc1 between blood-brain interfaces J Comp Neurol 2008, 510:497-507. 18680196
    • (2008) J Comp Neurol , vol.510 , pp. 497-507
    • Gazzin, S.1    Strazielle, N.2    Schmitt, C.3    Fevre-Montange, M.4    Ostrow, J.D.5    Tiribelli, C.6
  • 47
    • 0345688182 scopus 로고    scopus 로고
    • Transcriptional regulation of ABC drug transporters
    • 14576854
    • Scotto KW Transcriptional regulation of ABC drug transporters Oncogene 2003, 22:7496-7511. 14576854
    • (2003) Oncogene , vol.22 , pp. 7496-7511
    • Scotto, K.W.1
  • 48
    • 9944247695 scopus 로고    scopus 로고
    • Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism
    • 15581596
    • Eloranta JJ Kullak-Ublick GA Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism Arch Biochem Biophys 2005, 433:397-412. 15581596
    • (2005) Arch Biochem Biophys , vol.433 , pp. 397-412
    • Eloranta, J.J.1    Kullak-Ublick, G.A.2
  • 49
    • 34848824067 scopus 로고    scopus 로고
    • Role of human hepatocyte nuclear factor 4alpha in the expression of drug-metabolizing enzymes and transporters in human hepatocytes assessed by use of small interfering RNA
    • 17827783
    • Kamiyama Y Matsubara T Yoshinari K Nagata K Kamimura H Yamazoe Y Role of human hepatocyte nuclear factor 4alpha in the expression of drug-metabolizing enzymes and transporters in human hepatocytes assessed by use of small interfering RNA Drug Metab Pharmacokinet 2007, 22:287-298. 17827783
    • (2007) Drug Metab Pharmacokinet , vol.22 , pp. 287-298
    • Kamiyama, Y.1    Matsubara, T.2    Yoshinari, K.3    Nagata, K.4    Kamimura, H.5    Yamazoe, Y.6
  • 50
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • 325809 6828386
    • Dignam JD Lebovitz RM Roeder RG Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei Nucleic Acids Res 1983, 11:1475-1489. 325809 6828386
    • (1983) Nucleic Acids Res , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 52
    • 9444295988 scopus 로고    scopus 로고
    • A novel computational approach for the prediction of networked transcription factors of aryl hydrocarbon-receptor-regulated genes
    • 15342792
    • Kel A Reymann S Matys V Nettesheim P Wingender E Borlak J A novel computational approach for the prediction of networked transcription factors of aryl hydrocarbon-receptor-regulated genes Mol Pharmacol 2004, 66:1557-1572. 15342792
    • (2004) Mol Pharmacol , vol.66 , pp. 1557-1572
    • Kel, A.1    Reymann, S.2    Matys, V.3    Nettesheim, P.4    Wingender, E.5    Borlak, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.