메뉴 건너뛰기




Volumn 26, Issue 156, 2009, Pages 671-675

New derivatives of phenothiazines with anticancer activities;Nowe 1ochodne fenotiazyn o wlaściwościach przeciwnowotworowych

Author keywords

Anticancer activity; Azaphenothiazines; Gl 50; Phenothiazines; TGI i LC 50

Indexed keywords

ANTINEOPLASTIC AGENT; PHENOTHIAZINE DERIVATIVE;

EID: 67651167090     PISSN: 14269686     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (5)

References (31)
  • 1
    • 0035172946 scopus 로고    scopus 로고
    • Phenothiazines: Potential management of Creutzfeld-Jacob disease and its variants
    • Amaral L., Kristiansen J.E.: Phenothiazines: potential management of Creutzfeld-Jacob disease and its variants. Int. J. Antimicrob. Agents, 2001, 18,411-417.
    • (2001) Int. J. Antimicrob. Agents , vol.18 , pp. 411-417
    • Amaral, L.1    Kristiansen, J.E.2
  • 2
    • 0035657318 scopus 로고    scopus 로고
    • Phenothiazines: Potential alternatives for the management of antibiotics resistant infections of tuberculosis and malaria in developing countries
    • Amaral L., Viveiros M., Kristiannsen E.: Phenothiazines: potential alternatives for the management of antibiotics resistant infections of tuberculosis and malaria in developing countries. Trop. Med. Int. Health, 2001, 12, 1016-1022.
    • (2001) Trop. Med. Int. Health , vol.12 , pp. 1016-1022
    • Amaral, L.1    Viveiros, M.2    Kristiannsen, E.3
  • 3
    • 0344010203 scopus 로고    scopus 로고
    • Cancer chemopreventive effect of phenothiazines and related triheterocyciic analogues in the 12tetradecanoylphorbal-13-acetate promoted Epstein-Barr virus early antigen activation and the mouse skin two-stage carcenogenesis models
    • i wsp.
    • Azuine M.A., Tokuda H., Takayasu J. i wsp.: Cancer chemopreventive effect of phenothiazines and related triheterocyciic analogues in the 12tetradecanoylphorbal-13-acetate promoted Epstein-Barr virus early antigen activation and the mouse skin two-stage carcenogenesis models. Pharm. Res., 2004, 49, 161-169.
    • (2004) Pharm. Res. , vol.49 , pp. 161-169
    • Azuine, M.A.1    Tokuda, H.2    Takayasu, J.3
  • 5
    • 34547522758 scopus 로고    scopus 로고
    • Discovery of antiandrogen activity of nonsteroidal scaffolds of marketed drugs
    • i wsp.
    • Bisson W.H., Cheltsov A.V., Bruey-Sedano N. i wsp.: Discovery of antiandrogen activity of nonsteroidal scaffolds of marketed drugs. PNAS, 2007, 104, 11927-11932.
    • (2007) PNAS , vol.104 , pp. 11927-11932
    • Bisson, W.H.1    Cheltsov, A.V.2    Bruey-Sedano, N.3
  • 6
    • 34547760900 scopus 로고
    • Synthesis, properties and reactions of phenothiazines. W: Phenothiazines and 1,4-Benzothiazines
    • Gupta R.R. (red.). Amsterdam, Elsevier
    • Gupta R.R., Kumar M.: Synthesis, properties and reactions of phenothiazines. W: Phenothiazines and 1,4-Benzothiazines - Chemical and Biomedical Aspects. Gupta R.R. (red.). Amsterdam, Elsevier, 1988, 1-146.
    • (1988) Chemical and Biomedical Aspects , pp. 1-146
    • Gupta, R.R.1    Kumar, M.2
  • 7
    • 45249101333 scopus 로고    scopus 로고
    • Synthesis of 6-aminoalkyldiquino-1,4-thiazines and their acyl and sulfony derivatives
    • Jelen M., Pluta K.: Synthesis of 6-aminoalkyldiquino-1,4-thiazines and their acyl and sulfony derivatives. Heterocycles, 2008, 75, 859-870.
    • (2008) Heterocycles , vol.75 , pp. 859-870
    • Jelen, M.1    Pluta, K.2
  • 8
    • 0037222941 scopus 로고    scopus 로고
    • Zastosowanie farmakoterapii w leczeniu schizofrenii za pomoca klasycznych neuroleptyków z grupy pochodnych fenotiazyny
    • Kleszczewska E., Hejna J.: Zastosowanie farmakoterapii w leczeniu schizofrenii za pomoca klasycznych neuroleptyków z grupy pochodnych fenotiazyny. Pol. Merk. Lek., 2003, 80, 136-138.
    • (2003) Pol. Merk. Lek. , vol.80 , pp. 136-138
    • Kleszczewska, E.1    Hejna, J.2
  • 9
    • 0029958351 scopus 로고    scopus 로고
    • Correlation between topological resonance energy of metyl-substituted benzo[a]jphenothiazines, benzfcjacridines and their carcinogenic or antitumor activities
    • i wsp.
    • Kurihara T., Motohashi N., Pang G.L. i wsp.: Correlation between topological resonance energy of metyl-substituted benzo[a]jphenothiazines, benzfcjacridines and their carcinogenic or antitumor activities. Anticancer Res., 1996, 16, 2757-2766.
    • (1996) Anticancer Res. , vol.16 , pp. 2757-2766
    • Kurihara, T.1    Motohashi, N.2    Pang, G.L.3
  • 10
    • 33845386823 scopus 로고    scopus 로고
    • Targeting calmodulin in reversing multi drug resistance in cancer cells
    • Mayur Y.C., Jagadeesh S., Thimmaiah K.N.: Targeting calmodulin in reversing multi drug resistance in cancer cells. Mini Rev. Med. Chem., 2006, 6, 1383-1389.
    • (2006) Mini Rev. Med. Chem. , vol.6 , pp. 1383-1389
    • Mayur, Y.C.1    Jagadeesh, S.2    Thimmaiah, K.N.3
  • 11
    • 33748497379 scopus 로고    scopus 로고
    • Phenothiazine: The parent molecule
    • Mitchell S.C.: Phenothiazine: The parent molecule. Curr. Drug Targets, 2006, 7, 1181-1189.
    • (2006) Curr. Drug Targets , vol.7 , pp. 1181-1189
    • Mitchell, S.C.1
  • 12
    • 38149058890 scopus 로고    scopus 로고
    • Nowe wlasciwosci biologiczne neuroleptycznych fenotiazyn
    • Morak-Mlodawska B., Jelen M.: Nowe wlasciwosci biologiczne neuroleptycznych fenotiazyn. Pol. Merk. Lek., 2007, 138, 459-462.
    • (2007) Pol. Merk. Lek. , vol.138 , pp. 459-462
    • Morak-Mlodawska, B.1    Jelen, M.2
  • 13
    • 34547780024 scopus 로고    scopus 로고
    • Synthesis of novel dipyrido-1,4-thiazines
    • Morak-Mlodawska B., Pluta K.: Synthesis of novel dipyrido-1,4-thiazines. Heterocycles, 2007, 71, 1347-1361.
    • (2007) Heterocycles , vol.71 , pp. 1347-1361
    • Morak-Mlodawska, B.1    Pluta, K.2
  • 14
    • 33745814747 scopus 로고    scopus 로고
    • Phenothiazine molecule the basic chemical structure for various classes of pharmacotherapeutic agents
    • i wsp.
    • Mosnaim A.D., Ranade V.V., Wolf M.E. i wsp.: Phenothiazine molecule the basic chemical structure for various classes of pharmacotherapeutic agents. Am. J. Therapeutics, 2006, 13, 261-273.
    • (2006) Am. J. Therapeutics , vol.13 , pp. 261-273
    • Mosnaim, A.D.1    Ranade, V.V.2    Wolf, M.E.3
  • 15
    • 1842268447 scopus 로고
    • Antitumor activities of phenothiazines. W: Phenothiazines and 1,4-Benzothiazlnes
    • Gupta R.R. (red.). Amsterdam, Elsevier
    • Motohashi N.: Antitumor activities of phenothiazines. W: Phenothiazines and 1,4-Benzothiazlnes - Chemical and Biomedical Aspects. Gupta R.R. (red.). Amsterdam, Elsevier, 1988, 705-770.
    • (1988) Chemical and Biomedical Aspects , pp. 705-770
    • Motohashi, N.1
  • 16
    • 0034077804 scopus 로고    scopus 로고
    • Synthesis and biological activity of N-acylphenothiazines
    • i wsp.
    • Motohashi N., Kawase M., Saito S. i wsp.: Synthesis and biological activity of N-acylphenothiazines. Int. J. Antlmicrob. Agents, 2000, 14, 203-207.
    • (2000) Int. J. Antlmicrob. Agents , vol.14 , pp. 203-207
    • Motohashi, N.1    Kawase, M.2    Saito, S.3
  • 17
    • 0034329373 scopus 로고    scopus 로고
    • Antitumor potential and possible targets of phenothiazine-related compounds
    • i wsp.
    • Motohashi N., Kawase M., Saito S. i wsp.: Antitumor potential and possible targets of phenothiazine-related compounds. Curr. Drug Targets, 2000, 1,237-245.
    • (2000) Curr. Drug Targets , vol.1 , pp. 237-245
    • Motohashi, N.1    Kawase, M.2    Saito, S.3
  • 18
    • 0029966193 scopus 로고    scopus 로고
    • Synthesis and antitumor activity of 1-[2-(chloroethyl)-3-(-substituted- 10H-phenothiazin-10-yl)]alkyl-1ureas as potent anticancer agents
    • i wsp.
    • Motohashi N., Kawase M., Kurihara T. i wsp.: Synthesis and antitumor activity of 1-[2-(chloroethyl)-3-(-substituted-10H-phenothiazin-10-yl)]alkyl- 1ureas as potent anticancer agents. Anticancer Res., 1996, 16, 2525-2532.
    • (1996) Anticancer Res. , vol.16 , pp. 2525-2532
    • Motohashi, N.1    Kawase, M.2    Kurihara, T.3
  • 19
    • 33748509728 scopus 로고    scopus 로고
    • Cytotoxic potential of phenothiazines
    • i wsp.
    • Motohashi N., Kawase M., Satoh K. i wsp.: Cytotoxic potential of phenothiazines. Curr. Drug Targets, 2006, 7, 1055-1066.
    • (2006) Curr. Drug Targets , vol.7 , pp. 1055-1066
    • Motohashi, N.1    Kawase, M.2    Satoh, K.3
  • 20
    • 0032774025 scopus 로고    scopus 로고
    • Chemical structure and tumor type specificity of "half" phenothiazines
    • I wsp.
    • Motohashi N., Kurihara T., Sakagami H. I wsp.: Chemical structure and tumor type specificity of "half" phenothiazines. Anticancer Res., 1999, 19, 1859-1864.
    • (1999) Anticancer Res. , vol.19 , pp. 1859-1864
    • Motohashi, N.1    Kurihara, T.2    Sakagami, H.3
  • 21
    • 0029766160 scopus 로고    scopus 로고
    • Antitumor activity of phenothiazine-related compounds
    • i wsp.
    • Nagy S., Argyelan G., Moinar J. i wsp.: Antitumor activity of phenothiazine-related compounds. Anticancer Res., 1996, 16, 1915-1918.
    • (1996) Anticancer Res. , vol.16 , pp. 1915-1918
    • Nagy, S.1    Argyelan, G.2    Moinar, J.3
  • 22
    • 0032856051 scopus 로고    scopus 로고
    • Effects of psychotropic drugs on cell proliferation and differation
    • i wsp.
    • Nordenberg J., Fenig E., Landau M. i wsp.: Effects of psychotropic drugs on cell proliferation and differation. Biochem. Pharmacol., 1999, 58, 1229-1236.
    • (1999) Biochem. Pharmacol. , vol.58 , pp. 1229-1236
    • Nordenberg, J.1    Fenig, E.2    Landau, M.3
  • 23
    • 34248138748 scopus 로고    scopus 로고
    • Synthesis of new pentacyclic diquinothiazines
    • i wsp.
    • Nowak M., Pluta K., Suwiňska K. i wsp.: Synthesis of new pentacyclic diquinothiazines. J. Heterocyclic Chem., 2007, 44, 543-550.
    • (2007) J. Heterocyclic Chem. , vol.44 , pp. 543-550
    • Nowak, M.1    Pluta, K.2    Suwiňska, K.3
  • 24
    • 33747755812 scopus 로고    scopus 로고
    • Phenothiazine and carbazole-related compounds Inhibit mitotic kinesin Eg5 and trigger apoptosis in transformed culture cells
    • i wsp.
    • Okumara H., Nakazawa J., Tsuganezawa K. i wsp.: Phenothiazine and carbazole-related compounds Inhibit mitotic kinesin Eg5 and trigger apoptosis in transformed culture cells. Toxycology Lett., 2006, 166, 44-52.
    • (2006) Toxycology Lett. , vol.166 , pp. 44-52
    • Okumara, H.1    Nakazawa, J.2    Tsuganezawa, K.3
  • 25
    • 0035662285 scopus 로고    scopus 로고
    • Nowe leki przeciwnowotworowe - Postep czy stagnacja?
    • Pawlicki M., Wiczynska B.: Nowe leki przeciwnowotworowe - postep czy stagnacja? Nowotwory J. Oncol., 2001, 51, 507-514.
    • (2001) Nowotwory J. Oncol. , vol.51 , pp. 507-514
    • Pawlicki, M.1    Wiczynska, B.2
  • 27
    • 0034495201 scopus 로고    scopus 로고
    • Effects of antipsychotic drugs on cytokine networks
    • Pollmächer T., Hack M.: Effects of antipsychotic drugs on cytokine networks. J. Psych. Res., 2000, 34, 369-382.
    • (2000) J. Psych. Res. , vol.34 , pp. 369-382
    • Pollmächer, T.1    Hack, M.2
  • 28
    • 0030775166 scopus 로고    scopus 로고
    • The primary in vitro antitumor screening of half-mustard type phenothiazines
    • i wsp.
    • Wuonola M., A., Palfreyman M., G., Motohashi N. i wsp.: The primary in vitro antitumor screening of half-mustard type phenothiazines. Anticancer Res., 1997, 17, 3409-3423.
    • (1997) Anticancer Res. , vol.17 , pp. 3409-3423
    • Wuonola, M.A.1    Palfreyman, M.G.2    Motohashi, N.3
  • 29
    • 0030729028 scopus 로고    scopus 로고
    • The in vitro antitumor assay of half-mustard type phenothiazines in screens of AIDS-related leukemia and lymphomas
    • i wsp.
    • Wuonola M., A., Palfreyman M., G., Motohashi N. i wsp.: The in vitro antitumor assay of half-mustard type phenothiazines in screens of AIDS-related leukemia and lymphomas. Anticancer Res., 1997, 17, 3425-3429.
    • (1997) Anticancer Res. , vol.17 , pp. 3425-3429
    • Wuonola, M.A.1    Palfreyman, M.G.2    Motohashi, N.3
  • 31
    • 1442311053 scopus 로고    scopus 로고
    • Phenothiazines suppress proliferation and induce apoptosis in cultured leukemic cells without any influence on the viability of normal lymphocytes. Phenothiazines and leukemia
    • i wsp.
    • Zhelev Z., Ohba H., Bakalova R. i wsp.: Phenothiazines suppress proliferation and induce apoptosis in cultured leukemic cells without any influence on the viability of normal lymphocytes. Phenothiazines and leukemia. Cancer Chemother. Pharmacol., 2004, 53, 267-275.
    • (2004) Cancer Chemother. Pharmacol. , vol.53 , pp. 267-275
    • Zhelev, Z.1    Ohba, H.2    Bakalova, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.