Acute liver acetaminophen toxicity in rabbits and the use of antidotes: A metabonomic approach in serum

Journal of Applied Toxicology

Volumn 29, Issue 5, 2009, Pages 395-402

  Zira, Athina ^a,b   Mikros, Emmanuel ^b   Giannioti, Konstantina ^a   Galanopoulou, Panagiota ^a   Papalois, Apostolos ^c   Liapic, Charis ^a   Theocharis, Stamatios ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b UNIVERSITY OF ATHENS   (Greece)

^c Experimental Research Unit   (Greece)

Author keywords

Acetaminophen; Acute liver injury; Cimetidine; Metabonomics; N acetylcysteine; Nuclear magnetic resonance spectroscopy; Principal component analysis; Silybinin

Indexed keywords

ACETYLCYSTEINE; ALANINE AMINOTRANSFERASE; ANTIDOTE; ASPARTATE AMINOTRANSFERASE; CIMETIDINE; LIVER ENZYME; PARACETAMOL; SILIBININ;

ACUTE TOXICITY; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD ANALYSIS; BLOOD SAMPLING; CONTROLLED STUDY; HISTOPATHOLOGY; LIVER TOXICITY; METABOLOMICS; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RABBIT;

ACETAMINOPHEN; ACETYLCYSTEINE; ACUTE DISEASE; ALANINE TRANSAMINASE; ANIMALS; ANTIDOTES; ASPARTATE AMINOTRANSFERASES; BIOLOGICAL MARKERS; CIMETIDINE; DISEASE MODELS, ANIMAL; DRUG-INDUCED LIVER INJURY; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MALE; RABBITS; SILYMARIN;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 67651154372     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1425     Document Type: Article

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