Galactosylated alginate as a scaffold for hepatocytes entrapment

Biomaterials

Volumn 23, Issue 2, 2002, Pages 471-479

  Yang, Jun ^a   Goto, Mitsuaki ^b   Ise, Hirohiko ^c   Cho, Chong Su ^d   Akaike, Toshihiro ^a,c  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b Bio Quest Research Co Ltd   (Japan)

^c SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d Seoul National University   (South Korea)

Author keywords

Alginate; Bioartificial liver; Capsules; Galactose; Hepatocytes; Synthetic scaffold

Indexed keywords

CELLS; POLYSTYRENES; SYNTHESIS (CHEMICAL); UREA;

HIGHER CELL VIABILITY;

SUGAR (SUCROSE);

ALBUMIN; ALGINIC ACID; GALACTOSE; POLYSTYRENE;

ANIMAL CELL; ARTICLE; ARTIFICIAL LIVER; CELL ADHESION; CELL FUNCTION; CELL VIABILITY; CONTROLLED STUDY; ENCAPSULATION; LIVER; LIVER CELL; MALE; MICROCAPSULE; MOUSE; NONHUMAN; PHASE CONTRAST MICROSCOPY; PRIORITY JOURNAL; UREA CYCLE;

ALGINATES; ANIMALS; CELL ADHESION; GALACTOSE; GLUCURONIC ACID; HEPATOCYTES; HEXURONIC ACIDS; MALE; MICE; MICE, INBRED ICR;

EID: 0036131696     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0142-9612(01)00129-6     Document Type: Article

References (35)

1. Hepatocyte behavior within three-dimensional porous alginate scaffolds
2. Engineering of a sugar-derivatized porous network for hepatocyte culture
3. Design of hepatocyte-specific extracellular matrices for hybrid artificial liver
4. Alginates; biosynthess and structure-function relationships relevant to biomedical and biotechnological applications
5. Alginate as immobilization matrix for cells
6. Microencapsulation of living cells and tissues
7. A morphological and functional evaluation of transplanted isolated encapsulated hepatocytes following long-term transplantation in Gunn rats
8. Correction of bilirubin conjugation in the Gunn rat using hepatocytes immobilized in alginate gel beads as an extracorporeal bioartificial liver
9. Rapid formation of multicellular spheroids of adult rat hepatocytes by rotation culture and their immobilization within calcium alginate
10. Cell biology of hydrogels
11. Culture matrix configuration and composition in the maintenance of hepatocyte polarity and function
12. Switching from differentiation to growth in hepatocytes; control by extracellular matrix
13. Alginate hydrogels as synthetic extracellular matrix materials
14. Hepatocyte culture on carbohydrate-modified star polyethylene oxide hydrogels
15. Molecular design of three-dimensional artificial extracellular matrix; photosensitive polymers containing cell adhesive peptide
16. Rat hepatocytes bind to synthetic galactoside surfaces via a patch of asialoglycoprotein receptors
17. Carbohydrate-specific receptors of the liver
18. Enhanced division and survival efficiency of liver cells in culture dishes coated with a lactose carrying styrene homopolymer
19. Receptor-mediated formation of multilayer aggregates of primary rat hepatocytes on lactose-substituted polystyrene
20. Effect of supplemented EGF on multiplayer aggregation in rat hepatocyte primary culture
21. Synthesis and functions of polystyrene derivative having pendant oligosaccharides
22. Preparation of isolated rat liver cells
23. Microencapsulated islets as bioartificial endocrine pancreas
24. Regulation of differentiation and proliferation of rat hepatocytes by lactose-carrying polystyrene
25. 125I-labelled lactose-carrying polystyrene
26. Simple and reliable methods to assess hepatocyte viability in bioartificial liver support system matrices
27. In vitro study of multicellular hepatocyte spheroids formed in microcapsules
28. Differences in aggregation properties and levels of the neural cell adhesion molecule (NCAM) between islet types
29. 2+-dependent adhesion molecule, N-Cadherin in myoblast interaction during myogenesis
30. Rapid hepatocyte spheroid formation; optimization and long-term function in perfused microcapsules
31. Dependence of liver-specific transcription on tissue organization
32. Enhance cytochrome P450 IA1 activity of self-assembled rat hepatocyte spheroids