-
1
-
-
14244250617
-
Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation
-
Ali A.A., Weinstein R.S., Stewart S.A., Parfitt A.M., Manolagas S.C., and Jilka R.L. Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation. Endocrinology 146 (2005) 1226-1235
-
(2005)
Endocrinology
, vol.146
, pp. 1226-1235
-
-
Ali, A.A.1
Weinstein, R.S.2
Stewart, S.A.3
Parfitt, A.M.4
Manolagas, S.C.5
Jilka, R.L.6
-
3
-
-
12444273748
-
Distinct properties and advantages of a novel peroxisome proliferator-activated protein [gamma] selective modulator
-
Berger J.P., Petro A.E., Macnaul K.L., Kelly L.J., Zhang B.B., Richards K., Elbrecht A., Johnson B.A., Zhou G., Doebber T.W., Biswas C., Parikh M., Sharma N., Tanen M.R., Thompson G.M., Ventre J., Adams A.D., Mosley R., Surwit R.S., and Moller D.E. Distinct properties and advantages of a novel peroxisome proliferator-activated protein [gamma] selective modulator. Mol. Endocrinol. 17 (2003) 662-676
-
(2003)
Mol. Endocrinol.
, vol.17
, pp. 662-676
-
-
Berger, J.P.1
Petro, A.E.2
Macnaul, K.L.3
Kelly, L.J.4
Zhang, B.B.5
Richards, K.6
Elbrecht, A.7
Johnson, B.A.8
Zhou, G.9
Doebber, T.W.10
Biswas, C.11
Parikh, M.12
Sharma, N.13
Tanen, M.R.14
Thompson, G.M.15
Ventre, J.16
Adams, A.D.17
Mosley, R.18
Surwit, R.S.19
Moller, D.E.20
more..
-
4
-
-
33645394377
-
A novel partial agonist of peroxisome proliferator-activated receptor-gamma (PPARgamma) recruits PPARgamma- coactivator-1alpha, prevents triglyceride accumulation, and potentiates insulin signaling in vitro
-
Burgermeister E., Schnoebelen A., Flament A., Benz J., Stihle M., Gsell B., Rufer A., Ruf A., Kuhn B., Marki H.P., Mizrahi J., Sebokova E., Niesor E., and Meyer M. A novel partial agonist of peroxisome proliferator-activated receptor-gamma (PPARgamma) recruits PPARgamma- coactivator-1alpha, prevents triglyceride accumulation, and potentiates insulin signaling in vitro. Mol. Endocrinol. 20 (2006) 809-830
-
(2006)
Mol. Endocrinol.
, vol.20
, pp. 809-830
-
-
Burgermeister, E.1
Schnoebelen, A.2
Flament, A.3
Benz, J.4
Stihle, M.5
Gsell, B.6
Rufer, A.7
Ruf, A.8
Kuhn, B.9
Marki, H.P.10
Mizrahi, J.11
Sebokova, E.12
Niesor, E.13
Meyer, M.14
-
5
-
-
58549100843
-
Pioglitazone versus rosiglitazone: effects on lipids, lipoproteins, and apolipoproteins in head-to-head randomized clinical studies
-
Deeg M.A., and Tan M.H. Pioglitazone versus rosiglitazone: effects on lipids, lipoproteins, and apolipoproteins in head-to-head randomized clinical studies. PPAR. Res. (2008) 520465
-
(2008)
PPAR. Res.
, pp. 520465
-
-
Deeg, M.A.1
Tan, M.H.2
-
6
-
-
0037076294
-
Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II- infused rats: role of peroxisome proliferator-activated receptor-gamma
-
Diep Q.N., El M.M., Cohn J.S., Endemann D., Amiri F., Virdis A., Neves M.F., and Schiffrin E.L. Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II- infused rats: role of peroxisome proliferator-activated receptor-gamma. Circulation 105 (2002) 2296-2302
-
(2002)
Circulation
, vol.105
, pp. 2296-2302
-
-
Diep, Q.N.1
El, M.M.2
Cohn, J.S.3
Endemann, D.4
Amiri, F.5
Virdis, A.6
Neves, M.F.7
Schiffrin, E.L.8
-
7
-
-
0036727448
-
The role of PPARs in atherosclerosis
-
Duval C., Chinetti G., Trottein F., Fruchart J.C., and Staels B. The role of PPARs in atherosclerosis. Trends Mol. Med. 8 (2002) 422-430
-
(2002)
Trends Mol. Med.
, vol.8
, pp. 422-430
-
-
Duval, C.1
Chinetti, G.2
Trottein, F.3
Fruchart, J.C.4
Staels, B.5
-
8
-
-
33847041377
-
Comparison of the effects of pioglitazone and metformin on insulin resistance and hormonal markers in patients with impaired glucose tolerance and early diabetes
-
Eguchi K., Tomizawa H., Ishikawa J., Hoshide S., Numao T., Fukuda T., Shimada K., and Kario K. Comparison of the effects of pioglitazone and metformin on insulin resistance and hormonal markers in patients with impaired glucose tolerance and early diabetes. Hypertens. Res. 30 (2007) 23-30
-
(2007)
Hypertens. Res.
, vol.30
, pp. 23-30
-
-
Eguchi, K.1
Tomizawa, H.2
Ishikawa, J.3
Hoshide, S.4
Numao, T.5
Fukuda, T.6
Shimada, K.7
Kario, K.8
-
9
-
-
37349060123
-
The differential interactions of peroxisome proliferator-activated receptor gamma ligands with Tyr473 is a physical basis for their unique biological activities
-
Einstein M., Akiyama T.E., Castriota G.A., Wang C.F., McKeever B., Mosley R.T., Becker J.W., Moller D.E., Meinke P.T., Wood H.B., and Berger J.P. The differential interactions of peroxisome proliferator-activated receptor gamma ligands with Tyr473 is a physical basis for their unique biological activities. Mol. Pharmacol. 73 (2008) 62-74
-
(2008)
Mol. Pharmacol.
, vol.73
, pp. 62-74
-
-
Einstein, M.1
Akiyama, T.E.2
Castriota, G.A.3
Wang, C.F.4
McKeever, B.5
Mosley, R.T.6
Becker, J.W.7
Moller, D.E.8
Meinke, P.T.9
Wood, H.B.10
Berger, J.P.11
-
10
-
-
37649027471
-
Thiazolidinediones and fertility in polycystic ovary syndrome (PCOS)
-
Froment P., and Touraine P. Thiazolidinediones and fertility in polycystic ovary syndrome (PCOS). PPAR. Res. (2006) 73986
-
(2006)
PPAR. Res.
, pp. 73986
-
-
Froment, P.1
Touraine, P.2
-
11
-
-
0031054699
-
Cardiac and glycemic benefits of troglitazone treatment in NIDDM. The Troglitazone Study Group
-
Ghazzi M.N., Perez J.E., Antonucci T.K., Driscoll J.H., Huang S.M., Faja B.W., and Whitcomb R.W. Cardiac and glycemic benefits of troglitazone treatment in NIDDM. The Troglitazone Study Group. Diabetes 46 (1997) 433-439
-
(1997)
Diabetes
, vol.46
, pp. 433-439
-
-
Ghazzi, M.N.1
Perez, J.E.2
Antonucci, T.K.3
Driscoll, J.H.4
Huang, S.M.5
Faja, B.W.6
Whitcomb, R.W.7
-
12
-
-
38949088666
-
Soluble CD36 and risk markers of insulin resistance and atherosclerosis are elevated in polycystic ovary syndrome and significantly reduced during pioglitazone treatment
-
Glintborg D., Hojlund K., Andersen M., Henriksen J.E., Beck-Nielsen H., and Handberg A. Soluble CD36 and risk markers of insulin resistance and atherosclerosis are elevated in polycystic ovary syndrome and significantly reduced during pioglitazone treatment. Diabetes Care 31 (2008) 328-334
-
(2008)
Diabetes Care
, vol.31
, pp. 328-334
-
-
Glintborg, D.1
Hojlund, K.2
Andersen, M.3
Henriksen, J.E.4
Beck-Nielsen, H.5
Handberg, A.6
-
13
-
-
34147154970
-
The peroxisome proliferator-activated receptor-gamma agonist rosiglitazone decreases bone formation and bone mineral density in healthy postmenopausal women: a randomized, controlled trial
-
Grey A., Bolland M., Gamble G., Wattie D., Horne A., Davidson J., and Reid I.R. The peroxisome proliferator-activated receptor-gamma agonist rosiglitazone decreases bone formation and bone mineral density in healthy postmenopausal women: a randomized, controlled trial. J. Clin. Endocrinol. Metab 92 (2007) 1305-1310
-
(2007)
J. Clin. Endocrinol. Metab
, vol.92
, pp. 1305-1310
-
-
Grey, A.1
Bolland, M.2
Gamble, G.3
Wattie, D.4
Horne, A.5
Davidson, J.6
Reid, I.R.7
-
14
-
-
23844472901
-
Thiazolidinediones expand body fluid volume through PPARgamma stimulation of ENaC-mediated renal salt absorption
-
Guan Y., Hao C., Cha D.R., Rao R., Lu W., Kohan D.E., Magnuson M.A., Redha R., Zhang Y., and Breyer M.D. Thiazolidinediones expand body fluid volume through PPARgamma stimulation of ENaC-mediated renal salt absorption. Nat. Med. 11 (2005) 861-866
-
(2005)
Nat. Med.
, vol.11
, pp. 861-866
-
-
Guan, Y.1
Hao, C.2
Cha, D.R.3
Rao, R.4
Lu, W.5
Kohan, D.E.6
Magnuson, M.A.7
Redha, R.8
Zhang, Y.9
Breyer, M.D.10
-
15
-
-
0041766341
-
Activation of peroxisome proliferator-activated receptor-gamma inhibits differentiation of preosteoblasts
-
Khan E., and bu-Amer Y. Activation of peroxisome proliferator-activated receptor-gamma inhibits differentiation of preosteoblasts. J. Lab Clin. Med. 142 (2003) 29-34
-
(2003)
J. Lab Clin. Med.
, vol.142
, pp. 29-34
-
-
Khan, E.1
bu-Amer, Y.2
-
16
-
-
0034637218
-
Peroxisome proliferator-activated receptor and retinoid X receptor ligands inhibit monocyte chemotactic protein-1-directed migration of monocytes
-
Kintscher U., Goetze S., Wakino S., Kim S., Nagpal S., Chandraratna R.A., Graf K., Fleck E., Hsueh W.A., and Law R.E. Peroxisome proliferator-activated receptor and retinoid X receptor ligands inhibit monocyte chemotactic protein-1-directed migration of monocytes. Eur. J. Pharmacol. 401 (2000) 259-270
-
(2000)
Eur. J. Pharmacol.
, vol.401
, pp. 259-270
-
-
Kintscher, U.1
Goetze, S.2
Wakino, S.3
Kim, S.4
Nagpal, S.5
Chandraratna, R.A.6
Graf, K.7
Fleck, E.8
Hsueh, W.A.9
Law, R.E.10
-
17
-
-
10644251916
-
Peroxisome proliferator-activated receptor-gamma calls for activation in moderation: lessons from genetics and pharmacology
-
Knouff C., and Auwerx J. Peroxisome proliferator-activated receptor-gamma calls for activation in moderation: lessons from genetics and pharmacology. Endocr. Rev. 25 (2004) 899-918
-
(2004)
Endocr. Rev.
, vol.25
, pp. 899-918
-
-
Knouff, C.1
Auwerx, J.2
-
18
-
-
0041820128
-
Differential influences of peroxisome proliferator-activated receptors gamma and -alpha on food intake and energy homeostasis
-
Larsen P.J., Jensen P.B., Sorensen R.V., Larsen L.K., Vrang N., Wulff E.M., and Wassermann K. Differential influences of peroxisome proliferator-activated receptors gamma and -alpha on food intake and energy homeostasis. Diabetes 52 (2003) 2249-2259
-
(2003)
Diabetes
, vol.52
, pp. 2249-2259
-
-
Larsen, P.J.1
Jensen, P.B.2
Sorensen, R.V.3
Larsen, L.K.4
Vrang, N.5
Wulff, E.M.6
Wassermann, K.7
-
19
-
-
53049098128
-
Dissociation of antihyperglycaemic and adverse effects of partial perioxisome proliferator-activated receptor (PPAR-gamma) agonist balaglitazone
-
Larsen P.J., Lykkegaard K., Larsen L.K., Fleckner J., Sauerberg P., Wassermann K., and Wulff E.M. Dissociation of antihyperglycaemic and adverse effects of partial perioxisome proliferator-activated receptor (PPAR-gamma) agonist balaglitazone. Eur. J. Pharmacol. 596 (2008) 173-179
-
(2008)
Eur. J. Pharmacol.
, vol.596
, pp. 173-179
-
-
Larsen, P.J.1
Lykkegaard, K.2
Larsen, L.K.3
Fleckner, J.4
Sauerberg, P.5
Wassermann, K.6
Wulff, E.M.7
-
20
-
-
29344470714
-
Netoglitazone is a PPAR-gamma ligand with selective effects on bone and fat
-
Lazarenko O.P., Rzonca S.O., Suva L.J., and Lecka-Czernik B. Netoglitazone is a PPAR-gamma ligand with selective effects on bone and fat. Bone 38 (2006) 74-84
-
(2006)
Bone
, vol.38
, pp. 74-84
-
-
Lazarenko, O.P.1
Rzonca, S.O.2
Suva, L.J.3
Lecka-Czernik, B.4
-
21
-
-
0033197899
-
Inhibition of Osf2/Cbfa1 expression and terminal osteoblast differentiation by PPARgamma2
-
Lecka-Czernik B., Gubrij I., Moerman E.J., Kajkenova O., Lipschitz D.A., Manolagas S.C., and Jilka R.L. Inhibition of Osf2/Cbfa1 expression and terminal osteoblast differentiation by PPARgamma2. J. Cell. Biochem. 74 (1999) 357-371
-
(1999)
J. Cell. Biochem.
, vol.74
, pp. 357-371
-
-
Lecka-Czernik, B.1
Gubrij, I.2
Moerman, E.J.3
Kajkenova, O.4
Lipschitz, D.A.5
Manolagas, S.C.6
Jilka, R.L.7
-
22
-
-
0030774390
-
Selective breeding for diet-induced obesity and resistance in Sprague-Dawley rats
-
Levin B.E., Dunn-Meynell A.A., Balkan B., and Keesey R.E. Selective breeding for diet-induced obesity and resistance in Sprague-Dawley rats. Am. J. Physiol 273 (1997) R725-R730
-
(1997)
Am. J. Physiol
, vol.273
-
-
Levin, B.E.1
Dunn-Meynell, A.A.2
Balkan, B.3
Keesey, R.E.4
-
23
-
-
33748157382
-
Surface- specific effects of a PPARgamma agonist, darglitazone, on bone in mice
-
Li M., Pan L.C., Simmons H.A., Li Y., Healy D.R., Robinson B.S., Ke H.Z., and Brown T.A. Surface- specific effects of a PPARgamma agonist, darglitazone, on bone in mice. Bone 39 (2006) 796-806
-
(2006)
Bone
, vol.39
, pp. 796-806
-
-
Li, M.1
Pan, L.C.2
Simmons, H.A.3
Li, Y.4
Healy, D.R.5
Robinson, B.S.6
Ke, H.Z.7
Brown, T.A.8
-
24
-
-
67651137416
-
Long-term use of thiazolidinediones and fractures in type 2 diabetes: systematic review and meta-analysis
-
Loke Y.K., Singh S., and Furberg C.D. Long-term use of thiazolidinediones and fractures in type 2 diabetes: systematic review and meta-analysis. CMAJ (2008)
-
(2008)
CMAJ
-
-
Loke, Y.K.1
Singh, S.2
Furberg, C.D.3
-
26
-
-
34447334799
-
Effect of rosiglitazone/ramipril on preclinical vasculopathy in newly diagnosed, untreated diabetes and IGT patients: 1-year randomised, double-blind, placebo-controlled study
-
Rahman S., Ismail A.A., Ismail S.B., Naing N.N., and bdul Rahman A.R. Effect of rosiglitazone/ramipril on preclinical vasculopathy in newly diagnosed, untreated diabetes and IGT patients: 1-year randomised, double-blind, placebo-controlled study. Eur. J. Clin. Pharmacol. 63 (2007) 733-741
-
(2007)
Eur. J. Clin. Pharmacol.
, vol.63
, pp. 733-741
-
-
Rahman, S.1
Ismail, A.A.2
Ismail, S.B.3
Naing, N.N.4
bdul Rahman, A.R.5
-
27
-
-
34548303246
-
The rosiglitazone story--lessons from an FDA Advisory Committee meeting
-
Rosen C.J. The rosiglitazone story--lessons from an FDA Advisory Committee meeting. N. Engl. J. Med. 357 (2007) 844-846
-
(2007)
N. Engl. J. Med.
, vol.357
, pp. 844-846
-
-
Rosen, C.J.1
-
28
-
-
56749181186
-
Sugar and bone: a not-so sweet story
-
Rosen C.J. Sugar and bone: a not-so sweet story. J. Bone Miner. Res. 23 (2008) 1881-1883
-
(2008)
J. Bone Miner. Res.
, vol.23
, pp. 1881-1883
-
-
Rosen, C.J.1
-
29
-
-
29244440826
-
In vitro, ex vivo, and in vivo methodological approaches for studying therapeutic targets of osteoporosis and degenerative joint diseases: how biomarkers can assist?
-
Schaller S., Henriksen K., Hoegh-Andersen P., Sondergaard B.C., Sumer E.U., Tanko L.B., Qvist P., and Karsdal M.A. In vitro, ex vivo, and in vivo methodological approaches for studying therapeutic targets of osteoporosis and degenerative joint diseases: how biomarkers can assist?. Assay. Drug Dev. Technol. 3 (2005) 553-580
-
(2005)
Assay. Drug Dev. Technol.
, vol.3
, pp. 553-580
-
-
Schaller, S.1
Henriksen, K.2
Hoegh-Andersen, P.3
Sondergaard, B.C.4
Sumer, E.U.5
Tanko, L.B.6
Qvist, P.7
Karsdal, M.A.8
-
30
-
-
12344279757
-
The chloride channel inhibitor n53736 prevents bone resorption in ovariectomized rats without changing bone formation
-
Schaller S., Henriksen K., Sveigaard C., Heegaard A.M., Helix N., Stahlhut M., Ovejero M.C., Johansen J.V., Solberg H., Andersen T.L., Hougaard D., Berryman M., Shiodt C.B., Sorensen B.H., Lichtenberg J., Christophersen P., Foged N.T., Delaisse J.M., Engsig M.T., and Karsdal M.A. The chloride channel inhibitor n53736 prevents bone resorption in ovariectomized rats without changing bone formation. J. Bone Miner. Res. 19 (2004) 1144-1153
-
(2004)
J. Bone Miner. Res.
, vol.19
, pp. 1144-1153
-
-
Schaller, S.1
Henriksen, K.2
Sveigaard, C.3
Heegaard, A.M.4
Helix, N.5
Stahlhut, M.6
Ovejero, M.C.7
Johansen, J.V.8
Solberg, H.9
Andersen, T.L.10
Hougaard, D.11
Berryman, M.12
Shiodt, C.B.13
Sorensen, B.H.14
Lichtenberg, J.15
Christophersen, P.16
Foged, N.T.17
Delaisse, J.M.18
Engsig, M.T.19
Karsdal, M.A.20
more..
-
31
-
-
53149104764
-
TZDs and Bone: A Review of the Recent Clinical Evidence
-
2008
-
Schwartz A.V. TZDs and Bone: A Review of the Recent Clinical Evidence. PPAR. Res. (2008) 297893 2008
-
(2008)
PPAR. Res.
, pp. 297893
-
-
Schwartz, A.V.1
-
32
-
-
34548580881
-
Long-term risk of cardiovascular events with rosiglitazone: a meta-analysis
-
Singh S., Loke Y.K., and Furberg C.D. Long-term risk of cardiovascular events with rosiglitazone: a meta-analysis. JAMA 298 (2007) 1189-1195
-
(2007)
JAMA
, vol.298
, pp. 1189-1195
-
-
Singh, S.1
Loke, Y.K.2
Furberg, C.D.3
-
33
-
-
1642457244
-
Rosiglitazone activates renal sodium- and water-reabsorptive pathways and lowers blood pressure in normal rats
-
Song J., Knepper M.A., Hu X., Verbalis J.G., and Ecelbarger C.A. Rosiglitazone activates renal sodium- and water-reabsorptive pathways and lowers blood pressure in normal rats. J. Pharmacol. Exp. Ther 308 (2004) 426-433
-
(2004)
J. Pharmacol. Exp. Ther
, vol.308
, pp. 426-433
-
-
Song, J.1
Knepper, M.A.2
Hu, X.3
Verbalis, J.G.4
Ecelbarger, C.A.5
-
35
-
-
12344255130
-
Rosiglitazone impacts negatively on bone by promoting osteoblast/osteocyte apoptosis
-
Soroceanu M.A., Miao D., Bai X.Y., Su H., Goltzman D., and Karaplis A.C. Rosiglitazone impacts negatively on bone by promoting osteoblast/osteocyte apoptosis. J. Endocrinol. 183 (2004) 203-216
-
(2004)
J. Endocrinol.
, vol.183
, pp. 203-216
-
-
Soroceanu, M.A.1
Miao, D.2
Bai, X.Y.3
Su, H.4
Goltzman, D.5
Karaplis, A.C.6
-
36
-
-
37249051759
-
Suppression of PPAR transactivation switches cell fate of bone marrow stem cells from adipocytes into osteoblasts
-
Takada I., Suzawa M., Matsumoto K., and Kato S. Suppression of PPAR transactivation switches cell fate of bone marrow stem cells from adipocytes into osteoblasts. Ann. N.Y. Acad. Sci. 1116 (2007) 182-195
-
(2007)
Ann. N.Y. Acad. Sci.
, vol.1116
, pp. 182-195
-
-
Takada, I.1
Suzawa, M.2
Matsumoto, K.3
Kato, S.4
-
37
-
-
0034923501
-
Peroxisome proliferator-activated receptor gamma and metabolic disease
-
Willson T.M., Lambert M.H., and Kliewer S.A. Peroxisome proliferator-activated receptor gamma and metabolic disease. Annu. Rev. Biochem. 70 (2001) 341-367
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 341-367
-
-
Willson, T.M.1
Lambert, M.H.2
Kliewer, S.A.3
-
38
-
-
34249851341
-
Efficacy and safety of low-dose pioglitazone after primary coronary angioplasty with the use of bare metal stent in patients with acute myocardial infarction and with type 2 diabetes mellitus or impaired glucose tolerance
-
Yokoyama J., Sutoh N., Higuma T., Horiuchi D., Katoh C., Yokota T., Echizen T., Sasaki S., Hanada H., Osanai T., and Okumura K. Efficacy and safety of low-dose pioglitazone after primary coronary angioplasty with the use of bare metal stent in patients with acute myocardial infarction and with type 2 diabetes mellitus or impaired glucose tolerance. Heart Vessels 22 (2007) 146-151
-
(2007)
Heart Vessels
, vol.22
, pp. 146-151
-
-
Yokoyama, J.1
Sutoh, N.2
Higuma, T.3
Horiuchi, D.4
Katoh, C.5
Yokota, T.6
Echizen, T.7
Sasaki, S.8
Hanada, H.9
Osanai, T.10
Okumura, K.11
-
39
-
-
1642302410
-
Effects of the peroxisomal proliferator-activated receptor-gamma agonist pioglitazone on renal and hormonal responses to salt in healthy men
-
Zanchi A., Chiolero A., Maillard M., Nussberger J., Brunner H.R., and Burnier M. Effects of the peroxisomal proliferator-activated receptor-gamma agonist pioglitazone on renal and hormonal responses to salt in healthy men. J. Clin. Endocrinol. Metab 89 (2004) 1140-1145
-
(2004)
J. Clin. Endocrinol. Metab
, vol.89
, pp. 1140-1145
-
-
Zanchi, A.1
Chiolero, A.2
Maillard, M.3
Nussberger, J.4
Brunner, H.R.5
Burnier, M.6
|