-
2
-
-
33747892889
-
Pharmacological treatment of chronic heart failure
-
Adorisio R, DeLuca L, Rossi J, Gheorghiade M: Pharmacological treatment of chronic heart failure. Heart Fail Rev 2006, 11:109-123.
-
(2006)
Heart Fail Rev
, vol.11
, pp. 109-123
-
-
Adorisio, R.1
DeLuca, L.2
Rossi, J.3
Gheorghiade, M.4
-
3
-
-
0028183015
-
International Union of Pharmacology nomenclature of adrenoceptors
-
Bylund DB, Eikenberg DC, Hieble JP, et al.: International Union of Pharmacology nomenclature of adrenoceptors. Pharmacol Rev 1994, 46:121-136.
-
(1994)
Pharmacol Rev
, vol.46
, pp. 121-136
-
-
Bylund, D.B.1
Eikenberg, D.C.2
Hieble, J.P.3
-
4
-
-
0037050009
-
Seven-transmembrane-spanning receptors and heart function
-
Rockman HA, Koch WJ, Lefkowitz RJ: Seven-transmembrane-spanning receptors and heart function. Nature 2002, 415:206-212.
-
(2002)
Nature
, vol.415
, pp. 206-212
-
-
Rockman, H.A.1
Koch, W.J.2
Lefkowitz, R.J.3
-
5
-
-
0021194420
-
Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure
-
Cohn JN, Levine TB, Olivari MT, et al.: Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure. N Engl J Med 1984, 311:819-823.
-
(1984)
N Engl J Med
, vol.311
, pp. 819-823
-
-
Cohn, J.N.1
Levine, T.B.2
Olivari, M.T.3
-
6
-
-
0025812324
-
Model systems for the study of seven-transmembrane-segment receptors
-
Dohlman HG, Thorner J, Caron MG, Lefkowitz RJ: Model systems for the study of seven-transmembrane-segment receptors. Annu Rev Biochem 1991, 60:653-688.
-
(1991)
Annu Rev Biochem
, vol.60
, pp. 653-688
-
-
Dohlman, H.G.1
Thorner, J.2
Caron, M.G.3
Lefkowitz, R.J.4
-
7
-
-
0034620523
-
b-Adrenergic receptor blockade in chronic HF
-
Bristow MR: B-Adrenergic receptor blockade in chronic HF. Circulation 2000, 101:558-569.
-
(2000)
Circulation
, vol.101
, pp. 558-569
-
-
Bristow, M.R.1
-
8
-
-
0032729995
-
Opposing effects of b1- and b2-adrenergic receptors on cardiac myocyte apoptosis: Role of a pertussis toxin-sensitive G protein
-
Communal C, Singh K, Sawyer DB, Colucci WS: Opposing effects of b1- and b2-adrenergic receptors on cardiac myocyte apoptosis: Role of a pertussis toxin-sensitive G protein. Circulation 1999, 100:2210-2212.
-
(1999)
Circulation
, vol.100
, pp. 2210-2212
-
-
Communal, C.1
Singh, K.2
Sawyer, D.B.3
Colucci, W.S.4
-
9
-
-
0035852634
-
Dual modulation of cell survival and cell death by b2-adrenergic signaling in adult mouse cardiac myocytes
-
Zhu WZ, Zheng M, Koch WJ, et al.: Dual modulation of cell survival and cell death by b2-adrenergic signaling in adult mouse cardiac myocytes. Proc Natl Acad Sci U S A. 2001, 98:1607-1612.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 1607-1612
-
-
Zhu, W.Z.1
Zheng, M.2
Koch, W.J.3
-
10
-
-
0034636061
-
Early and delayed consequences of b2-adrenergic receptor overexpression in mouse hearts: Critical role for expression level
-
Liggett SB, Tepe NM, Lorenz JN, et al.: Early and delayed consequences of b2-adrenergic receptor overexpression in mouse hearts: Critical role for expression level. Circulation 2000, 101:1707-1714.
-
(2000)
Circulation
, vol.101
, pp. 1707-1714
-
-
Liggett, S.B.1
Tepe, N.M.2
Lorenz, J.N.3
-
11
-
-
0033535942
-
Progressive hypertrophy and heart failure in b1-adrenergic receptor transgenic mice
-
Engelhardt S, Hein L, Wiesmann F, Lohse MJ: Progressive hypertrophy and heart failure in b1-adrenergic receptor transgenic mice. Proc Natl Acad Sci U S A 1999, 96:7059-7064.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 7059-7064
-
-
Engelhardt, S.1
Hein, L.2
Wiesmann, F.3
Lohse, M.J.4
-
12
-
-
4844228660
-
Beneficial effects of chronic pharmacological manipulation of b-adrenoreceptor subtype signaling in rodent dilated ischemic cardiomyopathy
-
Ahmet I, Krawczyk M, Heller P, et al.: Beneficial effects of chronic pharmacological manipulation of b-adrenoreceptor subtype signaling in rodent dilated ischemic cardiomyopathy. Circulation 2004, 110:1083-1090.
-
(2004)
Circulation
, vol.110
, pp. 1083-1090
-
-
Ahmet, I.1
Krawczyk, M.2
Heller, P.3
-
13
-
-
0032745831
-
Enhancement of cardiac function after adenoviral-mediated in vivo intra-coronary b2-adrenergic receptor gene delivery
-
Maurice JP, Hata JA, Shah AS, et al.: Enhancement of cardiac function after adenoviral-mediated in vivo intra-coronary b2-adrenergic receptor gene delivery. J Clin Invest 1999, 104:21-29.
-
(1999)
J Clin Invest
, vol.104
, pp. 21-29
-
-
Maurice, J.P.1
Hata, J.A.2
Shah, A.S.3
-
14
-
-
41649114019
-
Targeted inhibition of cardiomyocyte Gi signaling enhances susceptibility to apoptotic cell death in response to ischemic stress
-
DeGeorge BR Jr, Gao E, Boucher M, et al.: Targeted inhibition of cardiomyocyte Gi signaling enhances susceptibility to apoptotic cell death in response to ischemic stress. Circulation 2008, 117:1378-1387.
-
(2008)
Circulation
, vol.117
, pp. 1378-1387
-
-
DeGeorge Jr., B.R.1
Gao, E.2
Boucher, M.3
-
15
-
-
0141457810
-
The b-adrenergic receptor kinase (bARK1) in heart failure
-
Petrofski JA, Koch WJ: The b-adrenergic receptor kinase (bARK1) in heart failure. J Mol Cell Cardiol 2003, 35:1167-1174.
-
(2003)
J Mol Cell Cardiol
, vol.35
, pp. 1167-1174
-
-
Petrofski, J.A.1
Koch, W.J.2
-
16
-
-
17644402459
-
Transduction of receptor signals by b-arrestins
-
Lefkowitz RJ, Shenoy SK: Transduction of receptor signals by b-arrestins. Science 2005, 308:512-517.
-
(2005)
Science
, vol.308
, pp. 512-517
-
-
Lefkowitz, R.J.1
Shenoy, S.K.2
-
18
-
-
0027481032
-
The binding site for the bg subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase
-
Koch WJ, Inglese J, Stone WC, Lefkowitz RJ: The binding site for the bg subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase. J Biol Chem 1993, 268:8256-8260.
-
(1993)
J Biol Chem
, vol.268
, pp. 8256-8260
-
-
Koch, W.J.1
Inglese, J.2
Stone, W.C.3
Lefkowitz, R.J.4
-
19
-
-
0029061324
-
Cardiac function in mice overexpressing the b-adrenergic receptor kinase or a bARK inhibitor
-
Koch WJ, Rockman HA, Samama P, et al.: Cardiac function in mice overexpressing the b-adrenergic receptor kinase or a bARK inhibitor. Science 1995, 268:1350-1353.
-
(1995)
Science
, vol.268
, pp. 1350-1353
-
-
Koch, W.J.1
Rockman, H.A.2
Samama, P.3
-
20
-
-
0035814968
-
In vivo ventricular gene delivery of a b-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction
-
Shah AS, White DC, Emani S, et al.: In vivo ventricular gene delivery of a b-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction. Circulation 2001, 103:1311-1316.
-
(2001)
Circulation
, vol.103
, pp. 1311-1316
-
-
Shah, A.S.1
White, D.C.2
Emani, S.3
-
21
-
-
0034625008
-
Preservation of myocardial b-adrenergic receptor delays the development of heart failure following myocardial infarction
-
White DC, Hata JA, Shah AS, et al.: Preservation of myocardial b-adrenergic receptor delays the development of heart failure following myocardial infarction. Proc Natl Acad Sci U S A 2000, 97:5428-5433.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 5428-5433
-
-
White, D.C.1
Hata, J.A.2
Shah, A.S.3
-
22
-
-
1842526833
-
Targeted b-adrenergic receptor kinase (bARK1) inhibition by gene transfer in failing human hearts
-
Williams ML, Hata JA, Schroder J, et al.: Targeted b-adrenergic receptor kinase (bARK1) inhibition by gene transfer in failing human hearts. Circulation 2004, 109:1590-1593.
-
(2004)
Circulation
, vol.109
, pp. 1590-1593
-
-
Williams, M.L.1
Hata, J.A.2
Schroder, J.3
-
23
-
-
59049097977
-
Myocardial adeno-associated virus serotype 6-bARKct gene therapy improves cardiac function and normalizes the neurohormonal axis in chronic heart failure
-
Rengo G, Lymperopoulos A, Zincarelli C, et al.: Myocardial adeno-associated virus serotype 6-bARKct gene therapy improves cardiac function and normalizes the neurohormonal axis in chronic heart failure. Circulation 2009, 119:89-98.
-
(2009)
Circulation
, vol.119
, pp. 89-98
-
-
Rengo, G.1
Lymperopoulos, A.2
Zincarelli, C.3
-
24
-
-
0032540893
-
Control of myocardial contractile function by the level of beta-adrenergic receptor kinase 1 in gene-targeted mice
-
Rockman HA, Choi DJ, Akhter SA, et al.: Control of myocardial contractile function by the level of beta-adrenergic receptor kinase 1 in gene-targeted mice. J Biol Chem 1998, 273:18180-18184.
-
(1998)
J Biol Chem
, vol.273
, pp. 18180-18184
-
-
Rockman, H.A.1
Choi, D.J.2
Akhter, S.A.3
-
25
-
-
50949099098
-
G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure
-
Raake PW, Vinge LE, Gao E, et al.: G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure. Circ Res 2008, 103:413-422.
-
(2008)
Circ Res
, vol.103
, pp. 413-422
-
-
Raake, P.W.1
Vinge, L.E.2
Gao, E.3
-
26
-
-
1942453389
-
Differential functional expression of human myocardial G protein receptor kinases in left ventricular cardiac diseases
-
Dzimiri N, Muiya P, Andres E, Al-Halees Z: Differential functional expression of human myocardial G protein receptor kinases in left ventricular cardiac diseases. Eur J Pharmacol 2004, 489:167-177.
-
(2004)
Eur J Pharmacol
, vol.489
, pp. 167-177
-
-
Dzimiri, N.1
Muiya, P.2
Andres, E.3
Al-Halees, Z.4
-
27
-
-
0033982570
-
Hybrid transgenic mice reveal in vivo specificity of G protein-coupled receptor kinases in the heart
-
Eckhart AD, Duncan SJ, Penn RB, et al.: Hybrid transgenic mice reveal in vivo specificity of G protein-coupled receptor kinases in the heart. Circ Res 2000, 86:43-50.
-
(2000)
Circ Res
, vol.86
, pp. 43-50
-
-
Eckhart, A.D.1
Duncan, S.J.2
Penn, R.B.3
-
28
-
-
43249124512
-
A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure
-
Liggett SB, Cresci S, Kelly RJ, et al.: A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure. Nat Med 2008, 14:510-517.
-
(2008)
Nat Med
, vol.14
, pp. 510-517
-
-
Liggett, S.B.1
Cresci, S.2
Kelly, R.J.3
-
29
-
-
34848820302
-
Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection
-
Noma T, Lemaire A, Naga Prasad SV, et al.: Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection. J Clin Invest 2007, 117:2396-2398.
-
(2007)
J Clin Invest
, vol.117
, pp. 2396-2398
-
-
Noma, T.1
Lemaire, A.2
Naga Prasad, S.V.3
-
30
-
-
50449087071
-
Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes
-
Martini JS, Raake P, Vinge LE, et al.: Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes. Proc Natl Acad Sci U S A 2008, 105:12457-12462.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 12457-12462
-
-
Martini, J.S.1
Raake, P.2
Vinge, L.E.3
-
31
-
-
33750802401
-
b-Arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes
-
Rajagopal K, Whalen EJ, Violin JD et al.: B-Arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes. Proc Natl Acad Sci U S A 2006, 103:16284-16289.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 16284-16289
-
-
Rajagopal, K.1
Whalen, E.J.2
Violin, J.D.3
-
32
-
-
38549107922
-
Signaling from beta1- and beta2-adrenergic receptors is defined by differential interactions with PDE4
-
Richter W, Day P, Agrawal R, et al.: Signaling from beta1- and beta2-adrenergic receptors is defined by differential interactions with PDE4. EMBO J 2008, 27:384-393.
-
(2008)
EMBO J
, vol.27
, pp. 384-393
-
-
Richter, W.1
Day, P.2
Agrawal, R.3
-
33
-
-
0041765759
-
Differential control of adrenal and sympathetic catecholamine release by alpha 2-adrenoceptor subtypes
-
Brede M, Nagy G, Philipp M, et al.: Differential control of adrenal and sympathetic catecholamine release by alpha 2-adrenoceptor subtypes. Mol Endocrinol 2003, 17:1640-1646.
-
(2003)
Mol Endocrinol
, vol.17
, pp. 1640-1646
-
-
Brede, M.1
Nagy, G.2
Philipp, M.3
-
34
-
-
33847728682
-
Adrenal GRK2 upregulation mediates sympathetic overdrive in heart failure
-
Lymperopoulos A, Rengo G, Funakoshi H, et al.: Adrenal GRK2 upregulation mediates sympathetic overdrive in heart failure. Nat Med 2007, 13:315-323.
-
(2007)
Nat Med
, vol.13
, pp. 315-323
-
-
Lymperopoulos, A.1
Rengo, G.2
Funakoshi, H.3
-
35
-
-
38649085669
-
Modulation of adrenal catecholamine secretion by in vivo gene transfer and manipulation of G protein-coupled receptor kinase-2 activity
-
Lymperopoulos A, Rengo G, Zincarelli C, et al.: Modulation of adrenal catecholamine secretion by in vivo gene transfer and manipulation of G protein-coupled receptor kinase-2 activity. Mol Ther 2008, 16:302-307.
-
(2008)
Mol Ther
, vol.16
, pp. 302-307
-
-
Lymperopoulos, A.1
Rengo, G.2
Zincarelli, C.3
-
36
-
-
0346613907
-
Neurohumoral blockade in CHF management
-
Willenbrock R, Philipp S, Mitrovic V, Dietz R: Neurohumoral blockade in CHF management. J Renin Angiotensin Aldosterone Syst 2000, 1(Suppl 1):24-30.
-
(2000)
J Renin Angiotensin Aldosterone Syst
, vol.1
, Issue.SUPPL. 1
, pp. 24-30
-
-
Willenbrock, R.1
Philipp, S.2
Mitrovic, V.3
Dietz, R.4
-
37
-
-
0038050389
-
Angiotensin type 2 receptor (AT2R): A challenging twin
-
Berk BC: Angiotensin type 2 reAeptor (AT2R): a challenging twin. Sci STKE 2003, 181:PE16.
-
(2003)
Sci STKE
, vol.181
-
-
Berk, B.C.1
-
38
-
-
0037512313
-
Chymase inhibition prevents cardiac fibrosis and improves diastolic dysfunction in the progression of heart failure
-
Matsumoto T, Wada A, Tsutamoto T, et al.: Chymase inhibition prevents cardiac fibrosis and improves diastolic dysfunction in the progression of heart failure. Circulation 2003, 107:2555-2558.
-
(2003)
Circulation
, vol.107
, pp. 2555-2558
-
-
Matsumoto, T.1
Wada, A.2
Tsutamoto, T.3
-
39
-
-
0242490542
-
Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both
-
Pfeffer MA, McMurray JJV, Velazquez EJ, et al.: Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med 2003, 349:1893-1906.
-
(2003)
N Engl J Med
, vol.349
, pp. 1893-1906
-
-
Pfeffer, M.A.1
McMurray, J.J.V.2
Velazquez, E.J.3
-
40
-
-
2942516035
-
Bradykinin contributes to the systemic hemodynamic effects of chronic angiotensin-converting enzyme inhibition in patients with heart failure
-
Cruden NL, Witherow FN, Webb DJ, et al.: Bradykinin contributes to the systemic hemodynamic effects of chronic angiotensin-converting enzyme inhibition in patients with heart failure. Arterioscler Thromb Vasc Biol 2004, 24:1043-1048.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 1043-1048
-
-
Cruden, N.L.1
Witherow, F.N.2
Webb, D.J.3
-
41
-
-
34447649922
-
Beta-arrestin-biased ligands at seven-transmembrane receptors
-
Violin JD, Lefkowitz RJ: Beta-arrestin-biased ligands at seven-transmembrane receptors. Trends Pharmacol Sci 2007, 28:416-422.
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 416-422
-
-
Violin, J.D.1
Lefkowitz, R.J.2
-
43
-
-
0037133628
-
BG9719 (CVT-124), an A1 adenosine receptor antagonist, protects against the decline in renal function observed with diuretic therapy
-
Gottlieb SS, Brater DC, Thomas I, et al.: BG9719 (CVT-124), an A1 adenosine receptor antagonist, protects against the decline in renal function observed with diuretic therapy. Circulation 2002, 105:1348-1353.
-
(2002)
Circulation
, vol.105
, pp. 1348-1353
-
-
Gottlieb, S.S.1
Brater, D.C.2
Thomas, I.3
-
44
-
-
0038380612
-
Ischaemic tolerance in aged mouse myocardium: The role of adenosine and effects of A1 adenosine receptor overexpression
-
Headrick JP, Willems L, Ashton KJ, et al.: Ischaemic tolerance in aged mouse myocardium: The role of adenosine and effects of A1 adenosine receptor overexpression. J Physiol 2003, 549:823-833.
-
(2003)
J Physiol
, vol.549
, pp. 823-833
-
-
Headrick, J.P.1
Willems, L.2
Ashton, K.J.3
-
45
-
-
18144447694
-
Activation of adenosine A1 receptor attenuates cardiac hypertrophy and prevents heart failure in murine left ventricular pressure-overload model
-
Liao Y, Takashima S, Asano Y, et al.: Activation of adenosine A1 receptor attenuates cardiac hypertrophy and prevents heart failure in murine left ventricular pressure-overload model. Circ Res 2003, 93:759-766.
-
(2003)
Circ Res
, vol.93
, pp. 759-766
-
-
Liao, Y.1
Takashima, S.2
Asano, Y.3
-
46
-
-
33751200636
-
Regulated overexpression of the A1-adenosine receptor in mice results in adverse but reversible changes in cardiac morphology and function
-
Funakoshi H, Chan TO, Good JC, et al.: Regulated overexpression of the A1-adenosine receptor in mice results in adverse but reversible changes in cardiac morphology and function. Circulation 2006, 114:2240-2250.
-
(2006)
Circulation
, vol.114
, pp. 2240-2250
-
-
Funakoshi, H.1
Chan, T.O.2
Good, J.C.3
-
47
-
-
67651142624
-
Cardiac-restricted overexpression of the A2A-adenosine receptor in FVB mice transiently increases contractile performance and rescues the heart failure phenotype in mice overexpressing the A1-adenosine receptor
-
Chan TO, Funakosji H, Song K, et al.: Cardiac-restricted overexpression of the A2A-adenosine receptor in FVB mice transiently increases contractile performance and rescues the heart failure phenotype in mice overexpressing the A1-adenosine receptor. Clin Trans Sci 2008, 1:126-133.
-
(2008)
Clin Trans Sci
, vol.1
, pp. 126-133
-
-
Chan, T.O.1
Funakosji, H.2
Song, K.3
-
48
-
-
40949132561
-
The endothelin system as therapeutic target in cardiovascular disease: Great expectations or bleak house?
-
Kirkby NS, Hadoke PWF, Bagnall AJ, Webb DJ: The endothelin system as therapeutic target in cardiovascular disease: Great expectations or bleak house? Br J Pharmacol 2008, 153:1105-1119.
-
(2008)
Br J Pharmacol
, vol.153
, pp. 1105-1119
-
-
Kirkby, N.S.1
Hadoke, P.W.F.2
Bagnall, A.J.3
Webb, D.J.4
-
49
-
-
0036710036
-
Function of the endothelin(B) receptor in cardiovascular physiology and pathophysiology
-
D'Orléans-Juste P, Labonté J, Bkaily G, et al.: Function of the endothelin(B) receptor in cardiovascular physiology and pathophysiology. Pharmacol Ther 2002, 221-238.
-
(2002)
Pharmacol Ther
, pp. 221-238
-
-
D'Orléans-Juste, P.1
Labonté, J.2
Bkaily, G.3
|