Discovery of iminosugar derivatives with strong IFN-γ inducing activity

ChemMedChem

Volumn 4, Issue 5, 2009, Pages 756-760

  Zhang, Lei ^a   Sun, Fang ^a   Wang, Qilong ^b   Zhou, Jing ^b   Zhang, Li He ^a   Zhang, Xiao Lian ^b   Ye, Xin Shan ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b WUHAN UNIVERSITY   (China)

Author keywords

Antibacterial agents; Iminosugars; Interferon ; Library screening; Synthesis

Indexed keywords

CARBOXYLIC ACID; GAMMA INTERFERON; IMINOSUGAR; ANTIINFECTIVE AGENT; BENZAMIDE DERIVATIVE; CARBOHYDRATE; QUINOLINOL DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL INFECTION; CARBON NUCLEAR MAGNETIC RESONANCE; CELL SCREENING; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL INFECTION; IMMUNOPHARMACOLOGY; IMMUNOSTIMULATION; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CHEMISTRY; DRUG DEVELOPMENT; DRUG EFFECT; METABOLISM; SALMONELLA TYPHIMURIUM; SYNTHESIS;

ANIMALS; ANTI-BACTERIAL AGENTS; BENZAMIDES; CARBOHYDRATES; DRUG DISCOVERY; HYDROXYQUINOLINES; IMINO SUGARS; INTERFERON-GAMMA; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; SALMONELLA TYPHIMURIUM;

EID: 67651112099     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.200900027     Document Type: Article

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