Revision of the guidelines of the Brazilian Medical Association for the treatment of depression (Complete version);Revisão das diretrizes da Associação Médica Brasileira para o tratamento da depressão (Versão integral)

Revista Brasileira de Psiquiatria

Volumn 31, Issue SUPPL. 1, 2009, Pages

  Fleck, Marcelo P ^a,b   Berlim, Marcelo T ^c,d   Lafer, Beny ^e   Sougey, Everton Botelho ^f   Del Porto, José Alberto ^g   Brasil, Marco Antônio ^h,i   Juruena, Mário Francisco ^e,j   Hetem, Luis Alberto ^e  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^c MCGILL UNIVERSITY   (Canada)

^d DOUGLAS MENTAL HEALTH UNIVERSITY INSTITUTE   (Canada)

^e UNIVERSITY OF SÃO PAULO   (Brazil)

^f FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

^g FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^h FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

ⁱ Associacao Brasileira de Psiquiatria   (Brazil)

^j KING'S COLLEGE LONDON   (United Kingdom)

more..

Author keywords

Depression; Diagnosis; Review; Sociology, medical; Treatment outcome

Indexed keywords

AGOMELATINE; AMFEBUTAMONE; AMITRIPTYLINE; ANTIDEPRESSANT AGENT; CITALOPRAM; CLOMIPRAMINE; DESVENLAFAXINE; DOPAMINE RECEPTOR STIMULATING AGENT; DULOXETINE; ESCITALOPRAM; FLUOXETINE; FLUVOXAMINE; IMIPRAMINE; MAPROTILINE; MIANSERIN; MIRTAZAPINE; MOCLOBEMIDE; MONOAMINE OXIDASE INHIBITOR; NORTRIPTYLINE; PAROXETINE; REBOXETINE; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TIANEPTINE; TRANYLCYPROMINE; TRAZODONE; TRICYCLIC ANTIDEPRESSANT AGENT; UNINDEXED DRUG; VENLAFAXINE;

BLOOD DYSCRASIA; BLURRED VISION; BRAZIL; CLINICAL TRIAL; CONSTIPATION; DEMOGRAPHY; DEPRESSION; DISABILITY; HEALTH CARE COST; HUMAN; HYPERTENSION; HYPERTENSIVE CRISIS; INSOMNIA; MEDICAL SOCIETY; NAUSEA; ORTHOSTATIC HYPOTENSION; PRACTICE GUIDELINE; PREVALENCE; PRIAPISM; PSYCHOTHERAPY; REVIEW; SEDATION; SEIZURE; SEXUAL DYSFUNCTION; SIDE EFFECT; SWEATING; URINE RETENTION; WEIGHT GAIN; XEROSTOMIA;

ANTIDEPRESSIVE AGENTS; BRAZIL; DEPRESSIVE DISORDER; HUMANS; PATIENT COMPLIANCE; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TREATMENT OUTCOME;

EID: 67651055406     PISSN: 15164446     EISSN: None     Source Type: Journal    
DOI: 10.1590/S1516-44462009000500003     Document Type: Review

References (161)

1. Waraich P, Goldner EM, Somers JM, Hsu L. Prevalence and incidence studies of mood disorders: a systematic review of the literature. Can J Psychiatry. 2004;49(2):124-138 (Pubitemid 38387422)
2. Mueller TI, Leon AC, Keller MB, Solomon DA, Endicott J, Coryell W, Warshaw M, Maser JD., Recurrence after recovery from major depressive disorder during 15 years of observational follow-up. Am J Psychiatry. 1999;156(7):1000-1006 (Pubitemid 29302790)
3. Kessler RC, Berglund P, Demler O, Jin R, Koretz D, Merikangas KR, Rush AJ, Walters EE, Wang PS; National Comorbidity Survey Replication. The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA. 2003;289(23):3095-3105 (Pubitemid 37432885)
4. Posternak MA, Solomon DA, Leon AC, Mueller TI, Shea MT, Endicott J, Keller MB. The naturalistic course of unipolar major depression in the absence of somatic therapy. J Nerv Ment Dis. 2006;194(5):324-329 (Pubitemid 43841196)
5. Keller MB, Lavori PW, Mueller TI, Endicott J, Coryell W, Hirschfeld RM, Shea T. Time to recovery, chronicity, and levels of psychopathology in major depression. A 5-year prospective follow-up of 431 subjects. Arch Gen Psychiatry. 1992;49(10):809-816
6. Wells KB, Stewart A, Hays RD, Burnam MA, Rogers W, Daniels M, Berry S, Greenfield S, Ware J. The functioning and well-being of depressed patients. Results from the Medical Outcomes Study. JAMA. 1989;262(7):914-919 (Pubitemid 19208948)
7. Penninx BW, Geerlings SW, Deeg DJ, van Eijk JT, van Tilburg W, Beekman AT. Minor and major depression and the risk of death in older persons. Arch Gen Psychiatry. 1999;56(10):889-895
8. Wulsin LR, Vaillant GE, Wells VE. A systematic review of the mortality of depression. Psychosom Med. 1999;61(1):6-17.
9. Evans DL, Charney DS, Lewis L, Golden RN, Gorman JM, Krishnan KR, Nemeroff CB, Bremner JD, Carney RM, Coyne JC, Delong MR, Frasure-Smith N, Glassman AH, Gold PW, Grant I, Gwyther L, Ironson G, Johnson RL, Kanner AM, Katon WJ, Kaufmann PG, Keefe FJ, Ketter T, Laughren TP, Leserman J, Lyketsos CG, McDonald WM, McEwen BS, Miller AH, Musselman D, O'Connor C, Petitto JM, Pollock BG, Robinson RG, Roose SP, Rowland J, Sheline Y, Sheps DS, Simon G, Spiegel D, Stunkard A, Sunderland T, Tibbits P Jr, Valvo WJ. Mood disorders in the medically ill: scientific review and recommendations. Biol Psychiatry. 2005;58(3):175-189 (Pubitemid 41112265)
10. Ormel J, Von Korff M, Van den Brink W, Katon W, Brilman E, Oldehinkel T. Depression, anxiety, and social disability show synchrony of change in primary care patients. Am J Public Health. 1993;83(3):385-390 (Pubitemid 23074827)
11. Lloyd KR,Jenkins R, Mann A. Long-term outcome of patients with neurotic illness in general practice. BMJ. 1996;313(7048):26-28 (Pubitemid 26229886)
12. Johnson J, Weissman MM, Klerman GL. Service utilization and social morbidity associated with depressive symptoms in the community. JAMA. 1992;267(11):1478-1483
13. Rost K, Zhang M, Fortney J, Smith J, Coyne J, Smith GR Jr. Persistently poor outcomes of undetected major depression in primary care. Gen Hosp Psychiatry. 1998;20(1):12-20. (Pubitemid 28109984)
14. Ronalds C, Creed F, Stone K, Webb S, Tomenson B. Outcome of anxiety and depressive disorders in primary care. Br J Psychiatr. 1997;171:427-433 (Pubitemid 27475839)
15. McQuaid JR, Stein MB, Laffaye C, McCahill ME. Depression in a primary care clinic: the prevalence and impact of an unrecognized disorder. J Affect Disord. 1999;55(1):1-10. (Pubitemid 29412909)
16. Docherty JP. Barriers to the diagnosis of depression in primary care. J Clin Psychiatry. 1997;58 Suppl 1:5-10. (Pubitemid 27098751)
17. Fleck MP, Lafer B, Sougey EB, Del Porto JA, Brasil MA, Juruena MF; Associação Médica Brasileira. Guidelines of the Brazilian Medical Association for the treatment of depression (complete version). Rev Bras Psiquiatr. 2003;25(2):114-122 (Pubitemid 37006440)
18. Anderson IM, Nutt DJ, Deakin JF. Evidence-based guidelines for treating depressive disorders with antidepressants: a revision of the 1993 British Association for Psychopharmacology guidelines. British Association for Psychopharmacology. J Psychopharmacol. 2000;14(1):3-20.
19. American Psychiatric Association. Practice guideline for the treatment of patients with major depressive disorder (revision). American Psychiatric Association. Am J Psychiatry. 2000;1-45.
20. Depression Guideline Panel. Depression in primary care in clinical practice guideline number 5. Vol.1. US Department of Health and Human Services: Rockville; 1993.
21. Depression Guideline Panel. Depression in primary care, in clinical practice guideline number 5. Vol.2. US Department of Health and Human Services: Rockville; 1993.
22. World Psychiatric Association. Educational program on depressive disorders. Overview and fundamental aspects. World Psychiatric Association: New York; 1997.
23. Qaseem A, Snow V, Denberg TD, Forciea MA, Owens DK; Clinical Efficacy Assessment Subcommittee of American College of Physicians. Using second-generation antidepressants to treat depressive disorders: a clinical practice guideline from the American College of Physicians. Ann Intern Med. 2008;149(10):725-733
24. Anderson IM, Ferrier IN, Baldwin RC, Cowen PJ, Howard L, Lewis G, Matthews K, McAllister-Williams RH, Peveler RC, Scott J, Tylee A. Evidence-based guidelines for treating depressive disorders with antidepressants: a revision of the 2000 British Association for Psychopharmacology guidelines. J Psychopharmacol. 2008;22(4):343-396
25. Bauer M, Bschor T, Pfennig A, Whybrow PC, Angst J, Versiani M, Möller HJ; WFSBP Task Force on Unipolar Depressive Disorders. World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders in Primary Care. World J Biol Psychiatry. 2007;8(2):67-104.
26. Ellis P, Royal Australian and New Zealand College of Psychiatrists Clinical Practice Guidelines Team for Depression. Australian and New Zealand clinical practice guidelines for the treatment of depression. Aust N Z J Psychiatry. 2004;38(6):389-407.
27. Bauer M, Whybrow PC, Angst J, Versiani M, Möller HJ; World Federation of Societies of Biological Psychiatry (WFSBF) Task Force on Treatment Guidelines for Unipolar Depressive Disorders. World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders, Part 2: Maintenance treatment of major depressive disorder and treatment of chronic depressive disorders and subthreshold depressions. World J Biol Psychiatry. 2002;3(2):69-86.
28. Regier DA, Narrow WE, Rae DS, Manderscheid RW, Locke BZ, Goodwin FK. The de facto US mental and addictive disorders service system. Epidemiologic catchment area prospective 1-year prevalence rates of disorders and services. Arch Gen Psychiatry.1993;50(2):85-94.
29. Kessler RC, McGonagle KA, Zhao S, Nelson CB, Hughes M, Eshleman S, Wittchen HU, Kendler KS. Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey. Arch Gen Psychiatry.1994;51(1):8-19. (Pubitemid 24028993)
30. Jenkins R, Lewis G, Bebbington P, Brugha T, Farrell M, Gill B, Meltzer H. The National Psychiatric Morbidity surveys of Great Britain - initial findings from the household survey. Psychol Med. 1997;27(4):775-789 (Pubitemid 27332165)
31. Ustun TB, Sartorius N. Mental inllness in primary care: an international study. New York: John Wiley & Sons; 1995.
32. Schleifer SJ, Macari-Hinson MM, Coyle DA, Slater WR, Kahn M, Gorlin R, Zucker HD. The nature and course of depression following myocardial infarction. Arch Intern Med. 1989;149(8):1785-1789 (Pubitemid 19200834)
33. Bukberg J, Penman D, Holland JC. Depression in hospitalized cancer patients. Psychosom Med. 1984;46(3):199-212. (Pubitemid 14111972)
34. Weissman MM, Bland RC, Canino GJ, Faravelli C, Greenwald S, Hwu HG, Joyce PR, Karam EG, Lee CK, Lellouch J, Lépine JP, Newman SC, Rubio-Stipec M, Wells JE, Wickramaratne PJ, Wittchen H, Yeh EK. Cross-national epidemiology of major depression and bipolar disorder. JAMA. 1996;276(4):293-299 (Pubitemid 26249533)
35. Judd LL, The clinical course of unipolar major depressive disorders. Arch Gen Psychiatry. 1997;54(11):989-991
36. Souery D, Oswald P, Massat I, Bailer U, Bollen J, Demyttenaere K, Kasper S, Lecrubier Y, Montgomery S, Serretti A, Zohar J, Mendlewicz J; Group for the Study of Resistant Depression. Clinical factors associated with treatment resistance in major depressive disorder: results from a European multicenter study. J Clin Psychiatry. 2007;68(7):1062-1070
37. Murray CJ, Lopez AD. Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study. Lancet. 1997;349(9063):1436- 1442 (Pubitemid 27212192)
38. Moussavi S, Chatterji S, Verdes E, Tandon A, Patel V, Ustun B. Depression, chronic diseases, and decrements in health: results from the World Health Surveys. Lancet. 2007;370(9590):851-858 (Pubitemid 47362344)
39. Freeling P, Rao BM, Paykel ES, Sireling LI, Burton RH. Unrecognised depression in general practice. Br Med J (Clin Res Ed). 1985;290(6485):1880-1883 (Pubitemid 15062855)
40. Tylee A, Freeling P, Kerry S, Burns T. How does the content of consultations affect the recognition by general practitioners of major depression in women? Br J Gen Pract. 1995;45(400):575-578
41. Davidson JR, Meltzer-Brody SE. The underrecognition and undertreatment of depression: what is the breadth and depth of the problem? J Clin Psychiatry. 1999;60 Suppl 7:4-11;
42. Rutz W, von Knorring L, Walinder J. Long-term effects of an educational program for general practitioners given by the Swedish Committee for the Prevention and Treatment of Depression. Acta Psychiatr Scand. 1992;85(1):83-88
43. Lin EH, Simon GE, Katzelnick DJ, Pearson SD. Does physician education on depression management improve treatment in primary care? J Gen Intern Med. 2001;16(9):614-619 (Pubitemid 32823892)
44. Simon GE, Fleck M, Lucas R, Bushnell DM; LIDO Group. Prevalence and predictors of depression treatment in an international primary care study. Am J Psychiatry. 2004;161(9):1626-1634 (Pubitemid 39201460)
45. World Health Organization. Classificação de transtornos mentais e de comportamento da CID-10: descrições clínicas e doretrizes diagnósticas. World Health Organization: Genebra; 1993.
46. Whooley MA, Avins AL, Miranda J, Browner WS. Case-finding instruments for depression. Two questions are as good as many. J Gen Intern Med. 1997;12(7):439-445 (Pubitemid 27300561)
47. Goldberg D, Bridges K, Duncan-Jones P, Grayson D. Detecting anxiety and depression in general medical settings. BMJ. 1988;297(6653):897-899 (Pubitemid 18234576)
48. Stewart JW, Quitkin FM, McGrath PJ. Social functioning in chronic depression: effect of 6 weeks of antidepressant treatment. Psychiatry Res. 1998;25:213-222
49. Cassano GB, Perugi G, Musetti L, Akiskal HS. The nature of depression presenting concomitantly with panic disorder. Compr Psychiatry. 1989;30(6):473-482 (Pubitemid 19279358)
50. Spitzer RL, Williams JB, Kroenke K, Linzer M, deGruy FV 3rd, Hahn SR, Brody D, Johnson JG. Utility of a new procedure for diagnosing mental disorders in primary care. The PRIME-MD 1000 study. JAMA. 1994;272(22):1749-1756
51. Leader JB, Klein DN. Social adjustment in dysthymia, double depression and episodic major depression. J Affect Disord. 1996;37(2-3):91-101.
52. Barrett JE, Barrett JA, Oxman TE, Gerber PD. The prevalence of psychiatric disorders in a primary care practice. Arch Gen Psychiatry. 1988;45(12):1100-1106 (Pubitemid 19005464)
53. Weisberg RB, Maki KM, Culpepper L, Keller MB. Is anyone really M.A.D.?: the occurrence and course of mixed anxiety-depressive disorder in a sample of primary care patients. J Nerv Ment Dis. 2005;193(4):223-230 (Pubitemid 40504616)
54. Angst J, Felder W, Frey R, Stassen HH. The course of affective disorders. I. Change of diagnosis of monopolar, unipolar, and bipolar illness. Arch Psychiatr Nervenkr. 1978;226(1):57-64. (Pubitemid 9046552)
55. Solomon DA, Keller MB, Leon AC, Mueller TI, Shea MT, Warshaw M, Maser JD, Coryell W, Endicott J. Recovery from major depression. A 10-year prospective follow-up across multiple episodes. Arch Gen Psychiatry. 1997;54(11):1001-1006 (Pubitemid 27476095)
56. Parker G, Parker K. Which antidepressants flick the switch? Aust N Z J Psychiatry. 2003;37(4):464-468 (Pubitemid 37121581)
57. Schulberg HC, Katon W, Simon GE, Rush AJ. Treating major depression in primary care practice: an update of the Agency for Health Care Policy and Research Practice Guidelines. Arch Gen Psychiatry. 1998;55(12):1121-1127 (Pubitemid 28558285)
58. Schulberg HC, Katon WJ, Simon GE, Rush AJ. Best clinical practice: guidelines for managing major depression in primary medical care. J Clin Psychiatry. 1999;60 Suppl 7:19-28. (Pubitemid 29227663)
59. Gill D, Hatcher S. A systematic review of the treatment of depression with antidepressant drugs in patients who also have a physical illness. J Psychosom Res. 1999;47(2):131-143 (Pubitemid 29468890)
60. Paykel ES, Hollyman JA, Freeling P, Sedgwick P. Predictors of therapeutic benefit from amitriptyline in mild depression: a general practice placebo-controlled trial. J Affect Disord. 1988;14(1):83-95. (Pubitemid 18016386)
61. Katon W, Robinson P, Von Korff M, Lin E, Bush T, Ludman E, Simon G, Walker E. A multifaceted intervention to improve treatment of depression in primary care. Arch Gen Psychiatry. 1996;53(10):924-932 (Pubitemid 26358007)
62. Kirsch I, Deacon BJ, Huedo-Medina TB, Scoboria A, Moore TJ, Johnson BT. Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration. PLoS Med. 2008;5(2):e45.
63. Spiker DG, Weiss JC, Dealy RS, Griffin SJ, Hanin I, Neil JF, Perel JM, Rossi AJ, Soloff PH. The pharmacological treatment of delusional depression. Am J Psychiatry. 1985;142(4):430-436
64. Shelton RC, Williamson DJ, Corya SA, Sanger TM, Van Campen LE, Case M, Briggs SD, Tollefson GD. Olanzapine/fluoxetine combination for treatment-resistant depression: a controlled study of SSRI and nortriptyline resistance. J Clin Psychiatry. 2005;66(10):1289-1297 (Pubitemid 41546509)
65. McIntyre RS, O'Donovan C. The human cost of not achieving full remission in depression. Can J Psychiatry. 2004;49(3 Suppl 1):10S-16S. (Pubitemid 38506487)
66. Kennedy SH, Emsley R. Placebo-controlled trial of agomelatine in the treatment of major depressive disorder. Eur Neuropsychopharmacol. 2006;16(2):93-100. (Pubitemid 43145814)
67. De Lima MS, Hotopf M. Benefits and risks of pharmacotherapy for dysthymia: a systematic appraisal of the evidence. Drug Saf. 2003;26(1):55-64. (Pubitemid 36092276)
68. Haby MM, Donnelly M, Corry J, Vos T. Cognitive behavioural therapy for depression, panic disorder and generalized anxiety disorder: a meta-regression of factors that may predict outcome. Aust N Z J Psychiatry. 2006;40(1):9-19. (Pubitemid 43337436)
69. Ekers D, Richards D, Gilbody S, A meta-analysis of randomized trials of behavioural treatment of depression. Psychol Med. 2008;38(5):611-623
70. de Mello MF, de Jesus Mari J, Bacaltchuk J, Verdeli H, Neugebauer R. A systematic review of research findings on the efficacy of interpersonal therapy for depressive disorders. Eur Arch Psychiatry Clin Neurosci. 2005;255(2):75-82. (Pubitemid 40575662)
71. Cuijpers P, van Straten A, Warmerdam L. Problem solving therapies for depression: a meta-analysis. Eur Psychiatry. 2007;22(1):9-15. (Pubitemid 46162183)
72. Leichsenring F, Rabung S, Leibing E. The efficacy of short-term psychodynamic psychotherapy in specific psychiatric disorders: a meta-analysis. Arch Gen Psychiatry. 2004;61(12):1208-1216 (Pubitemid 39602837)
73. Barbato A, D'Avanzo B. Marital therapy for depression. Cochrane Database Syst Rev. 2006(2):CD004188.
74. Bower P, Rowland N, Hardy R. The clinical effectiveness of counselling in primary care: a systematic review and meta-analysis. Psychol Med. 2003;33(2):203-215 (Pubitemid 36221453)
75. Song F, Freemantle N, Sheldon TA, House A, Watson P, Long A, Mason J. Selective serotonin reuptake inhibitors: meta-analysis of efficacy and acceptability. BMJ. 1993;306(6879):683-687 (Pubitemid 23070230)
76. Anderson I. Lessons to be learnt from meta-analyses of newer versus older antidepressants. Adv Psych Treatment. 1997;3:58-63.
77. Geddes JR, Freemantle N, Mason J, Eccles MP, Boynton J. SSRIs versus other antidepressants for depressive disorder. Cochrane Database Syst Rev. 2000(2):CD001851.
78. Montgomery SA. Long-term treatment of depression. Br J Psychiatry Suppl. 1994;(26):31-36 (Pubitemid 24358526)
79. Martin RM, Hilton SR, Kerry SM, Richards NM. General practitioners' perceptions of the tolerability of antidepressant drugs: a comparison of selective serotonin reuptake inhibitors and tricyclic antidepressants. BMJ. 1997;314(7081): 646-651 (Pubitemid 27099882)
80. Rosholm JU, Gram LF, Isacsson G, Hallas J, Bergman U. Changes in the pattern of antidepressant use upon the introduction of the new antidepressants: a prescription database study. Eur J Clin Pharmacol. 1997;52(3):205-209 (Pubitemid 27278375)
81. Donoghue J. Sub-optimal use of tricyclic antidepressants in primary care. Acta Psychiatr Scand. 1998;98(6):429-431 (Pubitemid 28566291)
82. Dunn RL, Donoghue JM, Ozminkowski RJ, Stephenson D, Hylan TR. Longitudinal patterns of antidepressant prescribing in primary care in the UK: comparison with treatment guidelines. J Psychopharmacol. 1999;13(2):136-143 (Pubitemid 29276823)
83. Furukawa TA, Kitamura T, Takahashi K. Treatment received by depressed patients in Japan and its determinants: naturalistic observation from a multi-center collaborative follow-up study. J Affect Disord. 2000;60(3):173-179 (Pubitemid 30829578)
84. Isacsson G, Boëthius G, Henriksson S, Jones JK, Bergman U. Selective serotonin reuptake inhibitors have broadened the utilisation of antidepressant treatment in accordance with recommendations. Findings from a Swedish prescription database. J Affect Disord. 1999;53(1):15-22. (Pubitemid 29227348)
85. Simon GE, Heiligenstein J, Revicki D, VonKorff M, Katon WJ, Ludman E, Grothaus L, Wagner E. Long-term outcomes of initial antidepressant drug choice in a "real world" randomized trial. Arch Fam Med. 1999;8(4):319-325
86. Frank L, Revicki DA, Sorensen SV, Shih YC. The economics of selective serotonin reuptake inhibitors in depression: a critical review. CNS Drugs. 2001;15(1):59-83. (Pubitemid 32128491)
87. Moller HJ. Is there evidence for negative effects of antidepressants on suicidality in depressive patients? A systematic review. Eur Arch Psychiatry Clin Neurosci. 2006;256(8):476-496 (Pubitemid 46020522)
88. Jick H, Kaye JA, Jick SS. Antidepressants and the risk of suicidal behaviors. JAMA. 2004;292(3):338-343 (Pubitemid 38944257)
89. Simon GE, Savarino J, Operskalski B, Wang PS. Suicide risk during antidepressant treatment. Am J Psychiatry. 2006;163(1):41-47
90. Katon W, Von Korff M, Lin E, Walker E, Simon GE, Bush T, Robinson P, Russo J. Collaborative management to achieve treatment guidelines. Impact on depression in primary care. JAMA. 1995;273(13):1026-1031
91. Posternak MA, Zimmerman M. Therapeutic effect of follow-up assessments on antidepressant and placebo response rates in antidepressant efficacy trials: meta-analysis. Br J Psychiatry. 2007;190:287-292 (Pubitemid 46580676)
92. Katz MM, Koslow SH, Maas JW, Frazer A, Bowden CL, Casper R, Croughan J, Kocsis J, Redmond E Jr. The timing, specificity and clinical prediction of tricyclic drug effects in depression. Psychol Med. 1987;17(2):297-309.
93. Koran LM, Hamilton SH, Hertzman M, Meyers BS, Halaris AE, Tollefson GD, Downs JM, Folks DG, Jeste DV, Lazarus LW. Predicting response to fluoxetine in geriatric patients with major depression. J Clin Psychopharmacol. 1995;15(6):421-427 (Pubitemid 26005592)
94. Quitkin FM, Rabkin JG, Ross D, McGrath PJ. Duration of antidepressant drug treatment. What is an adequate trial? Arch Gen Psychiatry. 1984;41(3):238-245 (Pubitemid 14168077)
95. Quitkin FM, McGrath PJ, Stewart JW, Ocepek-Welikson K, Taylor BP, Nunes E, Deliyannides D, Agosti V, Donovan SJ, Petkova E, Klein DF. Chronological milestones to guide drug change. When should clinicians switch antidepressants? Arch Gen Psychiatry. 1996;53(9):785-792 (Pubitemid 26303619)
96. Cramer JA, Rosenheck R. Compliance with medication regimens for mental and physical disorders. Psychiatr Serv. 1998;49(2):196-201. (Pubitemid 28071427)
97. Bielski RJ, Friedel RO. Prediction of tricyclic antidepressant response: a critical review. Arch Gen Psychiatry. 1976;33(12):1479-1489 (Pubitemid 8005007)
98. Conti L, Dell'Osso L. Clinical predictors of response to fluvoxamine, imipramine, and placebo. New Trends Exp Clin Psychiatry. 1989;5:221-229
99. Sotsky SM, Glass DR, Shea MT, Pilkonis PA, Collins JF, Elkin I, Watkins JT, Imber SD, Leber WR, Moyer J. Patient predictors of response to psychotherapy and pharmacotherapy: findings in the NIMH Treatment of Depression Collaborative Research Program. Am J Psychiatry. 1991;148(8):997-1008.
100. Mynors-Wallis L, Gath D. Predictors of treatment outcome for major depression in primary care. Psychol Med. 1997;27(3):731-736 (Pubitemid 27216198)
101. Lloyd C,,Zisook S, Click M Jr, Jaffe KE. Life events and response to antidepressants. J Human Stress. 1981;7(1):2-15.
102. Vallejo J, Gasto C, Catalan R, Bulbena A, Menchon JM. Predictors of antidepressant treatment outcome in melancholia: psychosocial, clinical and biological indicators. J Affect Disord. 1991;21(3):151-162
103. Kocsis JH, Croughan JL, Katz MM, Butler TP, Secunda S, Bowden CL, Davis JM. Response to treatment with antidepressants of patients with severe or moderate nonpsychotic depression and of patients with psychotic depression. Am J Psychiatry. 1990;147(5):621-624 (Pubitemid 20153434)
104. Nelson JC, Mazure CM, Jatlow PI. Does melancholia predict response in major depression? J Affect Disord. 1990;18(3):157-165 (Pubitemid 20069890)
105. Duggan CF, Lee AS, Murray RM. Do different subtypes of hospitalized depressives have different long-term outcomes? Arch Gen Psychiatry. 1991;48(4):308-312
106. Rush AJ, Weissenburger JE. Melancholic symptom features and DSM-IV. Am J Psychiatry. 1994; 151(4):489-498
107. Rothschild AJ. Management of psychotic, treatment-resistant depression. Psychiatr Clin North Am. 1996;19(2):237-252
108. Fava M, Uebelacker LA, Alpert JE, Nierenberg AA, Pava JA, Rosenbaum JF. Major depressive subtypes and treatment response. Biol Psychiatry. 1997;42(7):568-576 (Pubitemid 27425475)
109. Black DW, Bell S, Hulbert J, Nasrallah A. The importance of Axis II in patients with major depression. A controlled study. J Affect Disord. 1988;14(2):115-122 (Pubitemid 18060248)
110. Shea MT, Pilkonis PA, Beckham E, Collins JF, Elkin I, Sotsky SM, Docherty JP. Personality disorders and treatment outcome in the NIMH Treatment of Depression Collaborative Research Program. Am J Psychiatry. 1990;147(6):711-718 (Pubitemid 20188508)
111. Sato T, Sakado K, Sato S. Is there any specific personality disorder or personality disorder cluster that worsens the short-term treatment outcome of major depression? Acta Psychiatr Scand. 1993;88(5):342-349 (Pubitemid 23337559)
112. Surtees PG, Wainwright NW. Fragile states of mind: neuroticism, vulnerability and the long-term outcome of depression. Br J Psychiatry. 1996;169(3):338-347 (Pubitemid 126735387)
113. Ezquiaga E, García A, Bravo F, Pallarés T. Factors associated with outcome in major depression: a 6-month prospective study. Soc Psychiatry Psychiatr Epidemiol. 1998;33(11):552-557 (Pubitemid 28477087)
114. Gormley N, O'Leary D, Costello F. First admissions for depression: is the 'no-treatment interval' a critical predictor of time to remission? J Affect Disord. 1999;54(1-2):49-54.
115. Fleck MP, Horwath E. Pharmacologic management of difficult-to-treat depression in clinical practice. Psychiatr Serv. 2005;56(8):1005-1011 (Pubitemid 41098741)
116. Fava M, Rosenbaum JF, McGrath PJ, Stewart JW, Amsterdam JD, Quitkin FM. Lithium and tricyclic augmentation of fluoxetine treatment for resistant major depression: a double-blind, controlled study. Am J Psychiatry. 1994;151(9):1372-1374 (Pubitemid 24281764)
117. Rush AJ, Trivedi MH, Wisniewski SR, Stewart JW, Nierenberg AA, Thase ME, Ritz L, Biggs MM, Warden D, Luther JF, Shores-Wilson K, Niederehe G, Fava M; STAR*D Study Team. Bupropion-SR, sertraline, or venlafaxine-XR after failure of SSRIs for depression. N Engl J Med. 2006;354(12):1231-1242
118. Austin MP, Souza FG, Goodwin GM. Lithium augmentation in antidepressant-resistant patients. A quantitative analysis. Br J Psychiatry. 1991;159:510-514
119. Aronson R, Offman HJ, Joffe RT, Naylor CD., Triiodothyronine augmentation in the treatment of refractory depression. A meta-analysis. Arch Gen Psychiatry. 1996;53(9):842-848 (Pubitemid 26303624)
120. Nobler MS, Sackeim HA Refractory depression and eletroconvulsive therapy. In: Nolen WA, Zohar J, Roose SP, Amsterdam J, Editors. Refractory depression: current strategies and future directions. Chichester: John Wiley & Sons; 1994. p.69-81.
121. Thase ME, Psychotherapy of refractory depressions. Depress Anxiety. 1997;5(4):190-201.
122. Guthrie E, Moorey J, Margison F, Barker H, Palmer S, McGrath G, Tomenson B, Creed F. Cost-effectiveness of brief psychodynamic-interpersonal therapy in high utilizers of psychiatric services. Arch Gen Psychiatry. 1999;56(6):519-526 (Pubitemid 29304645)
123. Thase ME, Friedman ES, Biggs MM, Wisniewski SR, Trivedi MH, Luther JF, Fava M, Nierenberg AA, McGrath PJ, Warden D, Niederehe G, Hollon SD, Rush AJ. Cognitive therapy versus medication in augmentation and switch strategies as second-step treatments: a STAR*D report. Am J Psychiatry. 2007;164(5):739-752 (Pubitemid 46808529)
124. Rush AJ, Fava M, Wisniewski SR, Lavori PW, Trivedi MH, Sackeim HA, Thase ME, Nierenberg AA, Quitkin FM, Kashner TM, Kupfer DJ, Rosenbaum JF, Alpert J, Stewart JW, McGrath PJ, Biggs MM, Shores-Wilson K, Lebowitz BD, Ritz L, Niederehe G; STAR*D Investigators Group.Sequenced treatment alternatives to relieve depression (STAR*D): rationale and design. Control Clin Trials. 2004;25(1):119-142
125. Rush AJ, Trivedi MH, Wisniewski SR, Nierenberg AA, Stewart JW, Warden D, Niederehe G, Thase ME, Lavori PW, Lebowitz BD, McGrath PJ, Rosenbaum JF, Sackeim HA, Kupfer DJ, Luther J, Fava M. Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report. Am J Psychiatry. 2006;163(11):1905-1917 (Pubitemid 44807782)
126. UER GROUP. Efficacy and safety of electroconvulsive therapy in depressive disorders: a systematic review and meta-analysis. Lancet. 2003;361(9360):799- 808.
127. Pagnin D, de Queiroz V, Pini S, Cassano GB. Efficacy of ECT in depression: a meta-analytic review. J Ect. 2004;20(1):13-20. (Pubitemid 38488810)
128. Kho KH, van Vreeswijk MF, Simpson S, Zwinderman AH. A meta-analysis of electroconvulsive therapy efficacy in depression. J Ect. 2003;19(3):139-147 (Pubitemid 37087760)
129. Birkenhager TK, van den Broek WW, Moleman P, Bruijn JA. Outcome of a 4-step treatment algorithm for depressed inpatients. J Clin Psychiatry. 2006;67(8):1266-1271 (Pubitemid 44439700)
130. Herrmann LL, Ebmeier KP. Factors modifying the efficacy of transcranial magnetic stimulation in the treatment of depression: a review. J Clin Psychiatry. 2006;67(12):1870-1876 (Pubitemid 46048184)
131. Martin JL, Barbanoj MJ, Schlaepfer TE, Thompson E, Pérez V, Kulisevsky J. Repetitive transcranial magnetic stimulation for the treatment of depression. Systematic review and meta-analysis. Br J Psychiatry. 2003;182:480-491 (Pubitemid 36649193)
132. George MS, Rush AJ, Sackeim HA, Marangell LB. Vagus nerve stimulation (VNS): utility in neuropsychiatric disorders. Int J Neuropsychopharmacol. 2003;6(1):73-83. (Pubitemid 36373102)
133. Rush AJ, Marangell LB, Sackeim HA, George MS, Brannan SK, Davis SM, Howland R, Kling MA, Rittberg BR, Burke WJ, Rapaport MH, Zajecka J, Nierenberg AA, Husain MM, Ginsberg D, Cooke RG. Vagus nerve stimulation for treatment-resistant depression: a randomized, controlled acute phase trial. Biol Psychiatry. 2005;58(5):347-354 (Pubitemid 41219702)
134. George MS, Rush AJ, Marangell LB, Sackeim HA, Brannan SK, Davis SM, Howland R, Kling MA, Moreno F, Rittberg B, Dunner D, Schwartz T, Carpenter L, Burke M, Ninan P, Goodnick P. A one-year comparison of vagus nerve stimulation with treatment as usual for treatment-resistant depression. Biol Psychiatry. 2005;58(5):364-373 (Pubitemid 41219704)
135. Sartorius N, Baghai TC, Baldwin DS, Barrett B, Brand U, Fleischhacker W, Goodwin G, Grunze H, Knapp M, Leonard BE, Lieberman J, Nakane Y, Pinder RM, Schatzberg AF, Svestka J, Baumann P, Ghalib K, Markowitz JC, Padberg F, Fink M, Furukawa T, Fountoulakis KN, Jensen P, Kanba S, Riecher-Rössler A. Antidepressant medications and other treatments of depressive disorders: a CINP Task Force report based on a review of evidence. Int J Neuropsychopharmacol. 2007;10 Suppl 1: S1-207. (Pubitemid 351744817)
136. Kupfer DJ. Long-term treatment of depression. J Clin Psychiatry. 1991;52 Suppl:28-34.
137. Belsher G, Costello CG. Relapse after recovery from unipolar depression: a critical review. Psychol Bull. 1988;104(1):84-96.
138. Lin EH, Katon WJ, VonKorff M, Russo JE, Simon GE, Bush TM, Rutter CM, Walker EA, Ludman E. Relapse of depression in primary care. Rate and clinical predictors. Arch Fam Med. 1998;7(5):443-449 (Pubitemid 128435151)
139. Loonen AJ, Peer PG, Zwanikken GJ Continuation and maintenance therapy with antidepressive agents. Meta-analysis of research. Pharm Weekbl Sci. 1991;13(4):167-175
140. Kessing LV, Andersen PK. Predictive effects of previous episodes on the risk of recurrence in depressive and bipolar disorders. Curr Psychiatry Rep. 2005;7(6):413-420
141. Kanai T, Takeuchi H, Furukawa TA, Yoshimura R, Imaizumi T, Kitamura T, Takahashi K. Time to recurrence after recovery from major depressive episodes and its predictors. Psychol Med. 2003;33(5):839-845 (Pubitemid 36874663)
142. Ramana R, Paykel ES, Cooper Z, Hayhurst H, Saxty M, Surtees PG. Remission and relapse in major depression: a two-year prospective follow-up study. Psychol Med. 1995;25(6):1161-1170
143. Dotoli D, Spagnolo C, Bongiorno F, Zanardi R, Serretti A, Smeraldi E, Franchini L. Relapse during a 6-month continuation treatment with fluvoxamine in
144. McGrath PJ, Stewart JW, Quitkin FM, Chen Y, Alpert JE, Nierenberg AA, Fava M, Cheng J, Petkova E. Predictors of relapse in a prospective study of fluoxetine treatment of major depression. Am J Psychiatry. 2006;163(9):1542-1548 (Pubitemid 44465753)
145. Kessing LV. Subtypes of depressive episodes according to ICD-10: prediction of risk of relapse and suicide. Psychopathology. 2003;36(6):285-291
146. Kessing LV. Recurrence in affective disorder. II. Effect of age and gender. Br J Psychiatry. 1998;172:29-34. (Pubitemid 28122523)
147. Reimherr FW, Strong RE, Marchant BK, Hedges DW, Wender PH Factors affecting return of symptoms 1 year after treatment in a 62-week controlled study of fluoxetine in major depression. J Clin Psychiatry. 2001;62 Suppl 22:16-23.
148. Paykel ES, Tanner J. Life events, depressive relapse and maintenance treatment. Psychol Med. 1976;6(3):481-485
149. Dawson R, Lavori PW, Coryell WH, Endicott J, Keller MB. Maintenance strategies for unipolar depression: an observational study of levels of treatment and recurrence. J Affect Disord. 1998;49(1):31-44. (Pubitemid 28139095)
150. Frank E, Kupfer DJ, Perel JM, Cornes C, Mallinger AG, Thase ME, McEachran AB, Grochocinski VJ. Comparison of full-dose versus half-dose pharmacotherapy in the maintenance treatment of recurrent depression. J Affect Disord. 1993;27(3):139-145 (Pubitemid 23080331)
151. Franchini L, Gasperini M, Perez J, Smeraldi E, Zanardi R. Dose-response efficacy of paroxetine in preventing depressive recurrences: a randomized, double-blind study. J Clin Psychiatry. 1998;59(5):229-232 (Pubitemid 28274606)
152. Souza FG, Goodwin GM. Lithium treatment and prophylaxis in unipolar depression: a meta-analysis. Br J Psychiatry. 1991;158:666-675
153. Burgess S, Geddes J, Hawton K, Townsend E, Jamison K, Goodwin G. Lithium for maintenance treatment of mood disorders. Cochrane Database Syst Rev. 2001(3):CD003013.
154. Cipriani A, Smith K, Burgess S, Carney S, Goodwin G, Geddes J. Lithium versus antidepressants in the long-term treatment of unipolar affective disorder. Cochrane Database Syst Rev. 2006(4):CD003492. (Pubitemid 46841257)
155. Guzzetta F, Tondo L, Centorrino F, Baldessarini RJ. Lithium treatment reduces suicide risk in recurrent major depressive disorder. J Clin Psychiatry. 2007;68(3):380-383 (Pubitemid 46506801)
156. Dilsaver SC, Greden JF, Snider RM, Antidepressant withdrawal syndromes: phenomenology and pathophysiology. Int Clin Psychopharmacol. 1987;2(1):1-19.
157. Lejoyeux M, Ades J. Antidepressant discontinuation: a review of the literature. J Clin Psychiatry. 1997;58 Suppl 7:11-16
158. Haddad P. The SSRI discontinuation syndrome. J Psychopharmacol. 1998;12(3):305-313
159. Rosenbaum JF, Fava M, Hoog SL, Ascroft RC, Krebs WB. Selective serotonin reuptake inhibitor discontinuation syndrome: a randomized clinical trial. Biol Psychiatry. 1998;44(2):77-87. (Pubitemid 28305526)
160. Pagliaro LA, Pagliaro AM. Abuse potential of antidepressants: does it exist? CNS Drugs. 1995;4:247-252
161. Anderson IM. Selective serotonin reuptake inhibitors versus tricyclic antidepressants: a meta-analysis of efficacy and tolerability. J Affect Disord. 2000;58(1):19-36. (Pubitemid 30173208)