Acetonitrile-induced unfolding of porcine pepsin A. A proposal for a critical role of hydration structures in conformational stability

International Journal of Biological Macromolecules

Volumn 45, Issue 3, 2009, Pages 213-220

  Cardoso, T ^a   Oliveira, C ^a   Sarmento, A C ^a   Pereira, A ^a   Nutley, M A ^b   Jess, T ^b   Kelly, S M ^b   Cooper, A ^b   Price, N C ^b   Pires, E ^c   Barros, M ^c,d  

^a UNIVERSITY OF AVEIRO   (Portugal)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d Portuguese Catholic University Viseu   (Portugal)

Author keywords

Acetonitrile; Porcine pepsin A; Protein conformational stability; Protein denaturation

Indexed keywords

ACETONITRILE; PEPSIN A; SOLVENT;

ARTICLE; HYDRATION; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN DETERMINATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PROTEIN TERTIARY STRUCTURE; STRUCTURE ANALYSIS;

SUS;

EID: 67651036201     PISSN: 01418130     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijbiomac.2009.05.006     Document Type: Article

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