Getting mixed messages: The impact of conflicting social signals on the brain's target emotional response

NeuroImage

Volumn 47, Issue 4, 2009, Pages 1950-1959

  Amting, Jayna M ^a   Miller, Jodi E ^a   Chow, Melody ^a   Mitchell, Derek G V ^a  

^a WESTERN UNIVERSITY   (Canada)

Author keywords

Amygdala; Attention; Biased competition model; Emotional conflict; Emotional regulation; Social context

Indexed keywords

ADULT; AMYGDALOID NUCLEUS; ARTICLE; ATTENTION; BEHAVIOR CONTROL; CONFLICT; CONTROLLED STUDY; DECISION MAKING; EMOTION; FACIAL EXPRESSION; FEAR; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; ORBITAL CORTEX; PREFRONTAL CORTEX; PRIORITY JOURNAL; REACTION TIME; SOCIAL ENVIRONMENT; STIMULUS RESPONSE; TASK PERFORMANCE; VISUAL CORTEX; VISUAL STIMULATION;

ADOLESCENT; ADULT; BRAIN; CUES; EMOTIONS; FACIAL EXPRESSION; FEAR; FEMALE; HAPPINESS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; PERCEPTUAL MASKING; SOCIAL BEHAVIOR; YOUNG ADULT;

EID: 67651033280     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2009.05.011     Document Type: Article

References (72)

1. Adolphs R., Tranel D., Damasio H., and Damasio A. Impaired recognition of emotion in facial expressions following bilateral damage to the human amygdala. Nature 372 6507 (1994) 669-672
2. Allport D.A. Attention and Performance (1980), Roputledge and Kegan Paul, London
3. Amaral D.G., Behniea H., and Kelly J.L. Topographic organization of projections from the amygdala to the visual cortex in the macaque monkey. Neuroscience 118 4 (2003) 1099-1120
4. Anderson A.K., Christoff K., Panitz D., De Rosa E., and Gabrieli J.D. Neural correlates of the automatic processing of threat facial signals. J. Neurosci. 23 13 (2003) 5627-5633
5. Aron A.R., and Poldrack R.A. Cortical and subcortical contributions to Stop signal response inhibition: role of the subthalamic nucleus. J. Neurosci. 26 9 (2006) 2424-2433
6. Bishop S., Duncan J., Brett M., and Lawrence A.D. Prefrontal cortical function and anxiety: controlling attention to threat-related stimuli. Nat. Neurosci. 7 2 (2004) 184-188
7. Bishop S.J., Jenkins R., and Lawrence A.D. Neural processing of fearful faces: effects of anxiety are gated by perceptual capacity limitations. Cereb. Cortex 17 7 (2007) 1595-1603
8. Blair R.J.R., and Mitchell D.G.V. Psychopathy, attention and emotion. Psychol. Med. 39 4 (2009) 543-555
9. Blair R.J., Morris J.S., Frith C.D., Perrett D.I., and Dolan R.J. Dissociable neural responses to facial expressions of sadness and anger. Brain 122 Pt 5 (1999) 883-893
10. Breiter H.C., Etcoff N.L., Whalen P.J., Kennedy W.A., Rauch S.L., Buckner R.L., et al. Response and habituation of the human amygdala during visual processing of facial expression. Neuron 17 5 (1996) 875-887
11. Casey B.J., Forman S.D., Franzen P., Berkowitz A., Braver T.S., Nystrom L.E., et al. Sensitivity of prefrontal cortex to changes in target probability: a functional MRI study. Hum. Brain Mapp. 13 1 (2001) 26-33
12. Chen, G. (2008). Context-Dependent Correlation Analysis [Electronic Version]. AFNI/NIfTI Server. Retrieved September, 2008 from http://afni.nimh.nih.gov/sscc/gangc/CD-CorrAna_old.html.
13. Corbetta M., and Shulman G.L. Control of goal-directed and stimulus-driven attention in the brain. Nat. Rev. Neurosci. 3 3 (2002) 201-215
14. Cox R. AFNI: Software for analysis and visualization of functional magnetic resonance neuroimages. Comput. Biomed. Res. 29 3 (1996) 162-173
15. Cunningham W.A., Johnson M.K., Raye C.L., Chris Gatenby J., Gore J.C., and Banaji M.R. Separable neural components in the processing of black and white faces. Psychol. Sci. 15 12 (2004) 806-813
16. de Gelder B., Morris J.S., and Dolan R.J. Unconscious fear influences emotional awareness of faces and voices. Proc. Natl. Acad. Sci. U. S. A. 102 51 (2005) 18682-18687
17. Desimone R., and Duncan J. Neural mechanisms of selective visual attention. Annu. Rev. Neurosci. 18 (1995) 193-222
18. Dias R., Robbins T.W., and Roberts A.C. Dissociation in prefrontal cortex of affective and attentional shifts. Nature 380 6569 (1996) 69-72
19. Dolan R.J., Morris J.S., and de Gelder B. Crossmodal binding of fear in voice and face. Proc. Natl. Acad. Sci. U. S. A. 98 17 (2001) 10006-10010
20. Duncan J., Humphreys G., and Ward R. Competitive brain activity in visual attention. Curr. Opin. Neurobiol. 7 2 (1997) 255-261
21. Duncan J., Martens S., and Ward R. Restricted attentional capacity within but not between sensory modalities. Nature 387 6635 (1997) 808-810
22. Elliott R., Dolan R.J., and Frith C.D. Dissociable functions in the medial and lateral orbitofrontal cortex: evidence from human neuroimaging studies. Cereb. Cortex 10 3 (2000) 308-317
23. Elliott R., Newman J.L., Longe O.A., and Deakin J.F. Differential response patterns in the striatum and orbitofrontal cortex to financial reward in humans: a parametric functional magnetic resonance imaging study. J. Neurosci. 23 1 (2003) 303-307
24. Erthal F.S., de Oliveira L., Mocaiber I., Pereira M.G., Machado-Pinheiro W., Volchan E., et al. Load-dependent modulation of affective picture processing. Cogn. Affect Behav. Neurosci. 5 4 (2005) 388-395
25. Etkin A., Egner T., Peraza D.M., Kandel E.R., and Hirsch J. Resolving emotional conflict: a role for the rostral anterior cingulate cortex in modulating activity in the amygdala. Neuron 51 6 (2006) 871-882
26. Finger E.C., Mitchell D.G., Jones M., and Blair R.J. Dissociable roles of medial orbitofrontal cortex in human operant extinction learning. Neuroimage 43 4 (2008) 748-755
27. Garavan H., Pendergrass J.C., Ross T.J., Stein E.A., and Risinger R.C. Amygdala response to both positively and negatively valenced stimuli. Neuroreport 12 12 (2001) 2779-2783
28. Gorno-Tempini M.L., Pradelli S., Serafini M., Pagnoni G., Baraldi P., Porro C., et al. Explicit and incidental facial expression processing: an fMRI study. Neuroimage 14 2 (2001) 465-473
29. Haas B.W., Omura K., Constable R.T., and Canli T. Interference produced by emotional conflict associated with anterior cingulate activation. Cogn. Affect Behav. Neurosci. 6 2 (2006) 152-156
30. Hopfinger J.B., Buonocore M.H., and Mangun G.R. The neural mechanisms of top-down attentional control. Nat. Neurosci. 3 3 (2000) 284-291
31. Johnson M.H. Subcortical face processing. Nat. Rev. Neurosci. 6 10 (2005) 766-774
32. Kastner S., and Ungerleider L.G. The neural basis of biased competition in human visual cortex. Neuropsychologia 39 12 (2001) 1263-1276
33. Kastner S., De Weerd P., Desimone R., and Ungerleider L.G. Mechanisms of directed attention in the human extrastriate cortex as revealed by functional MRI. Science 282 5386 (1998) 108-111
34. Krolak-Salmon P., Henaff M.A., Vighetto A., Bertrand O., and Mauguiere F. Early amygdala reaction to fear spreading in occipital, temporal, and frontal cortex: a depth electrode ERP study in human. Neuron 42 4 (2004) 665-676
35. Lavie N. Perceptual load as a necessary condition for selective attention. J. Exp. Psychol. Hum. Percept. Perform 21 3 (1995) 451-468
36. Lavie N. The role of perceptual load in visual awareness. Brain Res. 1080 1 (2006) 91-100
37. LeDoux J. The Emotional Brain (1996), Simon and Schuster, New York
38. LeDoux J. The emotional brain, fear, and the amygdala. Cell Mol. Neurobiol. 23 4-5 (2003) 727-738
39. Luo Q., Holroyd T., Jones M., Hendler T., and Blair J. Neural dynamics for facial threat processing as revealed by gamma band synchronization using MEG. Neuroimage 34 2 (2007) 839-847
40. MacDonald III A.W., Cohen J.D., Stenger V.A., and Carter C.S. Dissociating the role of the dorsolateral prefrontal and anterior cingulate cortex in cognitive control. Science 288 5472 (2000) 1835-1838
41. Mitchell D.G.V., Richell R.A., Leonard A., and Blair R.J. Emotion at the expense of cognition: psychopathic individuals outperform controls on an operant response task. J. Abnorm. Psychol. 115 3 (2006) 559-566
42. Mitchell D.G.V., Nakic M., Fridberg D., Kamel N., Pine D.S., and Blair R.J.R. The impact of processing load on emotion. NeuroImage 34 (2007) 1299-1309
43. Mitchell D.G., Luo Q., Mondillo K., Vythilingam M., Finger E.C., and Blair R.J. The interference of operant task performance by emotional distracters: an antagonistic relationship between the amygdala and frontoparietal cortices. Neuroimage 40 2 (2008) 859-868
44. Morris J.S., Frith C.D., Perrett D.I., Rowland D., Young A.W., Calder A.J., et al. A differential neural response in the human amygdala to fearful and happy facial expressions. Nature 383 6603 (1996) 812-815
45. Morris J.S., Friston K.J., Buchel C., Frith C.D., Young A.W., Calder A.J., et al. A neuromodulatory role for the human amygdala in processing emotional facial expressions. Brain 121 Pt 1 (1998) 47-57
46. Morris J.S., Ohman A., and Dolan R.J. A subcortical pathway to the right amygdala mediating "unseen" fear. Proc. Natl. Acad. Sci. U. S. A. 96 4 (1999) 1680-1685
47. Morris J.S., Buchel C., and Dolan R.J. Parallel neural responses in amygdala subregions and sensory cortex during implicit fear conditioning. Neuroimage 13 6 Pt 1 (2001) 1044-1052
48. Morris J.S., de Gelder B., Weiskrantz L., and Dolan R.J. Differential extrageniculostriate and amygdala responses to presentation of emotional faces in a cortically blind field. Brain 124 Pt 6 (2001) 1241-1252
49. Nagahama Y., Okada T., Katsumi Y., Hayashi T., Yamauchi H., Oyanagi C., et al. Dissociable mechanisms of attentional control within the human prefrontal cortex. Cereb Cortex 11 1 (2001) 85-92
50. Nitschke J.B., Nelson E.E., Rusch B.D., Fox A.S., Oakes T.R., and Davidson R.J. Orbitofrontal cortex tracks positive mood in mothers viewing pictures of their newborn infants. Neuroimage 21 2 (2004) 583-592
51. O'Doherty J., Kringelbach M.L., Rolls E.T., Hornak J., and Andrews C. Abstract reward and punishment representations in the human orbitofrontal cortex. Nat. Neurosci. 4 1 (2001) 95-102
52. Ohman A. The role of the amygdala in human fear: automatic detection of threat. Psychoneuroendocrinology 30 10 (2005) 953-958
53. Ongur D., and Price J.L. The organization of networks within the orbital and medial prefrontal cortex of rats, monkeys and humans. Cereb. Cortex 10 3 (2000) 206-219
54. Pegna A.J., Khateb A., Lazeyras F., and Seghier M.L. Discriminating emotional faces without primary visual cortices involves the right amygdala. Nat. Neurosci. 8 1 (2005) 24-25
55. Pessoa L. On the relationship between emotion and cognition. Nat. Rev. Neurosci. 9 2 (2008) 148-158
56. Pessoa L., and Ungerleider L.G. Neuroimaging studies of attention and the processing of emotion-laden stimuli. Prog. Brain Res. 144 (2004) 171-182
57. Pessoa L., Kastner S., and Ungerleider L.G. Attentional control of the processing of neural and emotional stimuli. Brain Res. Cogn. Brain Res. 15 1 (2002) 31-45
58. Pessoa L., McKenna M., Gutierrez E., and Ungerleider L.G. Neural processing of emotional faces requires attention. Proc. Natl. Acad. Sci. U. S. A. 99 17 (2002) 11458-11463
59. Pessoa L., Padmala S., and Morland T. Fate of unattended fearful faces in the amygdala is determined by both attentional resources and cognitive modulation. Neuroimage 28 1 (2005) 249-255
60. Pezawas L., Meyer-Lindenberg A., Drabant E.M., Verchinski B.A., Munoz K.E., Kolachana B.S., et al. 5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression. Nat. Neurosci. 8 6 (2005) 828-834
61. Pourtois G., Schwartz S., Seghier M.L., Lazeyras F., and Vuilleumier P. Neural systems for orienting attention to the location of threat signals: an event-related fMRI study. Neuroimage 31 2 (2006) 920-933
62. Reynolds J.H., Chelazzi L., and Desimone R. Competitive mechanisms subserve attention in macaque areas V2 and V4. J. Neurosci. 19 5 (1999) 1736-1753
63. Rogers R.D., Owen A.M., Middleton H.C., Williams E.J., Pickard J.D., Sahakian B.J., et al. Choosing between small, likely rewards and large, unlikely rewards activates inferior and orbital prefrontal cortex. J. Neurosci. 19 20 (1999) 9029-9038
64. Rosenkranz J.A., and Grace A.A. Dopamine attenuates prefrontal cortical suppression of sensory inputs to the basolateral amygdala of rats. J. Neurosci. 21 11 (2001) 4090-4103
65. Rowe G., Hirsh J.B., and Anderson A.K. Positive affect increases the breadth of attentional selection. Proc. Natl. Acad. Sci. U. S. A. 104 1 (2007) 383-388
66. Schneider W., Eschman A., and Zuccolotto A. E-Prime User's Guide Version 1 (2002), Psychology Software Tools Inc, Pittsburgh
67. Vuilleumier P. How brains beware: neural mechanisms of emotional attention. Trends Cogn. Sci. 9 12 (2005) 585-594
68. Vuilleumier P., and Driver J. Modulation of visual processing by attention and emotion: windows on causal interactions between human brain regions. Philos. Trans. R Soc. Lond. B Biol. Sci. 362 1481 (2007) 837-855
69. Vuilleumier P., and Pourtois G. Distributed and interactive brain mechanisms during emotion face perception: evidence from functional neuroimaging. Neuropsychologia 45 1 (2007) 174-194
70. Vuilleumier P., Armony J.L., Driver J., and Dolan R.J. Effects of attention and emotion on face processing in the human brain: an event-related fMRI study. Neuron 30 3 (2001) 829-841
71. Wegener D., Galashan F.O., Markowski D.N., and Kreiter A.K. Selective visual attention ensures constancy of sensory representations: testing the influence of perceptual load and spatial competition. Vision Res. 46 21 (2006) 3563-3574
72. Yang T.T., Menon V., Eliez S., Blasey C., White C.D., Reid A.J., et al. Amygdalar activation associated with positive and negative facial expressions. Neuroreport 13 14 (2002) 1737-1741