Osteopontin promotes fibrosis in dystrophic mouse muscle by modulating immune cell subsets and intramuscular TGF-β

Journal of Clinical Investigation

Volumn 119, Issue 6, 2009, Pages 1583-1594

  Vetrone, Sylvia A ^a,b   Montecino Rodriguez, Encarnacion ^a   Kudryashova, Elena ^a   Kramerova, Irina ^a   Hoffman, Eric P ^c   Liu, Scot D ^a   Miceli, M Carrie ^a   Spencer, Melissa J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Molecular Cellular and Integrative Physiology Program   (United States)

^c CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; OSTEOPONTIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CELL SURVIVAL; CONTROLLED STUDY; DUCHENNE MUSCULAR DYSTROPHY; FEMALE; GENE; MALE; MDX GENE; MOUSE; MUSCLE CELL; MYOFIBROSIS; NATURAL KILLER T CELL; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE;

AGING; ANIMALS; DIAPHRAGM; FIBROSIS; GENE EXPRESSION REGULATION; HEART DISEASES; HUMANS; IMMUNE SYSTEM PROCESSES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCULAR DYSTROPHY, ANIMAL; MUTATION; OSTEOPONTIN; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTES; TRANSFORMING GROWTH FACTOR BETA;

EID: 67651005390     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI37662     Document Type: Article

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