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Volumn 20, Issue 2, 2005, Pages 250-256

Upregulation of osteopontin by osteocytes deprived of mechanical loading or oxygen

Author keywords

Bone resorption; Disuse; Hypoxia; Immobilization; Mechanotransduction; Osteopenia

Indexed keywords

MESSENGER RNA; OSTEOPONTIN; OXYGEN; PROTEIN KINASE C;

EID: 12544255780     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/JBMR.041004     Document Type: Article
Times cited : (70)

References (47)
  • 3
    • 0029360476 scopus 로고
    • Uniformity of resorptive bone loss induced by disuse
    • Gross TS, Rubin CT 1995 Uniformity of resorptive bone loss induced by disuse. J Orthop Res 13:708-714.
    • (1995) J Orthop Res , vol.13 , pp. 708-714
    • Gross, T.S.1    Rubin, C.T.2
  • 4
    • 0037566322 scopus 로고    scopus 로고
    • Molecular mechanisms underlying osteoclast formation and activation
    • Troen BR 2003 Molecular mechanisms underlying osteoclast formation and activation. Exp Gerontol 38:605-614.
    • (2003) Exp Gerontol , vol.38 , pp. 605-614
    • Troen, B.R.1
  • 6
    • 0033529194 scopus 로고    scopus 로고
    • Osteopontin-deficient mice are resistant to ovariectomy-induced bone resorption
    • Yoshitake H, Rittling SR, Denhardt DT, Noda M 1999 Osteopontin-deficient mice are resistant to ovariectomy-induced bone resorption. Proc Natl Acad Sci USA 96:8156-8160.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 8156-8160
    • Yoshitake, H.1    Rittling, S.R.2    Denhardt, D.T.3    Noda, M.4
  • 9
    • 0032432558 scopus 로고    scopus 로고
    • Osteopontin expression and function: Role in bone remodeling
    • Denhardt DT, Noda M 1998 Osteopontin expression and function: Role in bone remodeling. J Cell Biochem Suppl 30-31:92-102.
    • (1998) J Cell Biochem Suppl , vol.30-31 , pp. 92-102
    • Denhardt, D.T.1    Noda, M.2
  • 10
    • 0035992868 scopus 로고    scopus 로고
    • Colocalization of intracellular osteopontin with CD44 is associated with migration, cell fusion, and resorption in osteoclasts
    • Suzuki K, Zhu B, Rittling SR, Denhardt DT, Goldberg HA, McCulloch CA, Sodek J 2002 Colocalization of intracellular osteopontin with CD44 is associated with migration, cell fusion, and resorption in osteoclasts. J Bone Miner Res 17:1486-1497.
    • (2002) J Bone Miner Res , vol.17 , pp. 1486-1497
    • Suzuki, K.1    Zhu, B.2    Rittling, S.R.3    Denhardt, D.T.4    Goldberg, H.A.5    McCulloch, C.A.6    Sodek, J.7
  • 12
    • 0028826051 scopus 로고
    • Mechanically induced periosteal bone formation is paralleled by the upregulation of collagen type one mRNA in osteocytes as measured by in situ reverse transcript-polymerase chain reaction
    • Sun YQ, McLeod KJ, Rubin CT 1995 Mechanically induced periosteal bone formation is paralleled by the upregulation of collagen type one mRNA in osteocytes as measured by in situ reverse transcript-polymerase chain reaction. Calcif Tissue Int 57:456-462.
    • (1995) Calcif Tissue Int , vol.57 , pp. 456-462
    • Sun, Y.Q.1    McLeod, K.J.2    Rubin, C.T.3
  • 13
  • 14
    • 0033022781 scopus 로고    scopus 로고
    • Increased expression of matrix metalloproteinase-1 in osteocytes precedes bone resorption as stimulated by disuse: Evidence for autoregulation of the cell's mechanical environment?
    • Rubin C, Sun YQ, Hadjiargyrou M, McLeod K 1999 Increased expression of matrix metalloproteinase-1 in osteocytes precedes bone resorption as stimulated by disuse: Evidence for autoregulation of the cell's mechanical environment? J Orthop Res 17:354-361.
    • (1999) J Orthop Res , vol.17 , pp. 354-361
    • Rubin, C.1    Sun, Y.Q.2    Hadjiargyrou, M.3    McLeod, K.4
  • 15
    • 0032852497 scopus 로고    scopus 로고
    • Osteocyte hypoxia: A novel mechanotransduction pathway
    • Dodd JS, Raleigh JA, Gross TS 1999 Osteocyte hypoxia: A novel mechanotransduction pathway. Am J Physiol 277:C589-C602.
    • (1999) Am J Physiol , vol.277
    • Dodd, J.S.1    Raleigh, J.A.2    Gross, T.S.3
  • 18
    • 0034981380 scopus 로고    scopus 로고
    • Hypoxia stimulates osteopontin expression and proliferation of cultured vascular smooth muscle cells: Potentiation by high glucose
    • Sodhi CP, Phadke SA, Batlle D, Sahai A 2001 Hypoxia stimulates osteopontin expression and proliferation of cultured vascular smooth muscle cells: Potentiation by high glucose. Diabetes 50:1482-1490.
    • (2001) Diabetes , vol.50 , pp. 1482-1490
    • Sodhi, C.P.1    Phadke, S.A.2    Batlle, D.3    Sahai, A.4
  • 19
    • 0033588077 scopus 로고    scopus 로고
    • Transient upregulation of osteopontin mRNA in hippocampus and striatum following global forebrain ischemia in rats
    • Lee MY, Shin SL, Choi YS, Kim EJ, Cha JH, Chun MH, Lee SB, Kim SY 1999 Transient upregulation of osteopontin mRNA in hippocampus and striatum following global forebrain ischemia in rats. Neurosci Lett 271:81-84.
    • (1999) Neurosci Lett , vol.271 , pp. 81-84
    • Lee, M.Y.1    Shin, S.L.2    Choi, Y.S.3    Kim, E.J.4    Cha, J.H.5    Chun, M.H.6    Lee, S.B.7    Kim, S.Y.8
  • 20
    • 0021322767 scopus 로고
    • Regulation of bone formation by applied dynamic loads
    • Rubin CT, Lanyon LE 1984 Regulation of bone formation by applied dynamic loads. J Bone Joint Surg Am 66:397-402.
    • (1984) J Bone Joint Surg Am , vol.66 , pp. 397-402
    • Rubin, C.T.1    Lanyon, L.E.2
  • 21
    • 0032544465 scopus 로고    scopus 로고
    • Detection of mouse osteopontin by western blotting
    • Rittling SR, Feng F 1998 Detection of mouse osteopontin by western blotting. Biochem Biophys Res Commun 250:287-292.
    • (1998) Biochem Biophys Res Commun , vol.250 , pp. 287-292
    • Rittling, S.R.1    Feng, F.2
  • 23
    • 0036708150 scopus 로고    scopus 로고
    • Low-magnitude mechanical loading becomes osteogenic when rest is inserted between each load cycle
    • Srinivasan S, Weimer DA, Agans SC, Bain SD, Gross TS 2002 Low-magnitude mechanical loading becomes osteogenic when rest is inserted between each load cycle. J Bone Miner Res 17:1613-1620.
    • (2002) J Bone Miner Res , vol.17 , pp. 1613-1620
    • Srinivasan, S.1    Weimer, D.A.2    Agans, S.C.3    Bain, S.D.4    Gross, T.S.5
  • 25
    • 0036688817 scopus 로고    scopus 로고
    • Osteopontin deficiency increases mineral content and mineral crystallinity in mouse bone
    • Boskey AL, Spevak L, Paschalis E, Doty SB, McKee MD 2002 Osteopontin deficiency increases mineral content and mineral crystallinity in mouse bone. Calcif Tissue Int 71:145-154.
    • (2002) Calcif Tissue Int , vol.71 , pp. 145-154
    • Boskey, A.L.1    Spevak, L.2    Paschalis, E.3    Doty, S.B.4    McKee, M.D.5
  • 26
    • 0035059244 scopus 로고    scopus 로고
    • Temporal and spatial gene expression of major bone extracellular matrix molecules during embryonic mandibular osteogenesis in rats
    • Zhu JX, Sasano Y, Takahashi I, Mizoguchi I, Kagayama M 2001 Temporal and spatial gene expression of major bone extracellular matrix molecules during embryonic mandibular osteogenesis in rats. Histochem J 33:25-35.
    • (2001) Histochem J , vol.33 , pp. 25-35
    • Zhu, J.X.1    Sasano, Y.2    Takahashi, I.3    Mizoguchi, I.4    Kagayama, M.5
  • 30
    • 0027471503 scopus 로고
    • Developmental expression of osteopontin (OPN) mRNA in rat tissues: Evidence for a role for OPN in bone formation and resorption
    • Chen J, Singh K, Mukherjee BB, Sodek J 1993 Developmental expression of osteopontin (OPN) mRNA in rat tissues: Evidence for a role for OPN in bone formation and resorption. Matrix 13:113-123.
    • (1993) Matrix , vol.13 , pp. 113-123
    • Chen, J.1    Singh, K.2    Mukherjee, B.B.3    Sodek, J.4
  • 31
    • 0035918140 scopus 로고    scopus 로고
    • Osteopontin gene regulation by oscillatory fluid flow via intracellular calcium mobilization and activation of mitogen-activated protein kinase in MC3T3-E1 osteoblasts
    • You J, Reilly GC, Zhen X, Yellowley CE, Chen Q, Donahue HJ, Jacobs CR 2001 Osteopontin gene regulation by oscillatory fluid flow via intracellular calcium mobilization and activation of mitogen-activated protein kinase in MC3T3-E1 osteoblasts. J Biol Chem 276:13365-13371.
    • (2001) J Biol Chem , vol.276 , pp. 13365-13371
    • You, J.1    Reilly, G.C.2    Zhen, X.3    Yellowley, C.E.4    Chen, Q.5    Donahue, H.J.6    Jacobs, C.R.7
  • 34
    • 0036138631 scopus 로고    scopus 로고
    • Osteopontin posttranslational modifications, possibly phosphorylation, are required for in vitro bone resorption but not osteoclast adhesion
    • Razzouk S, Brunn JC, Qin C, Tye CE, Goldberg HA, Butler WT 2002 Osteopontin posttranslational modifications, possibly phosphorylation, are required for in vitro bone resorption but not osteoclast adhesion. Bone 30:40-47.
    • (2002) Bone , vol.30 , pp. 40-47
    • Razzouk, S.1    Brunn, J.C.2    Qin, C.3    Tye, C.E.4    Goldberg, H.A.5    Butler, W.T.6
  • 35
    • 0345528053 scopus 로고    scopus 로고
    • Probing the tissue to subcellular level structure underlying bone's molecular sieving function
    • Tami AE, Schaffler MB, Knothe Tate ML 2003 Probing the tissue to subcellular level structure underlying bone's molecular sieving function. Biorheology 40:577-590.
    • (2003) Biorheology , vol.40 , pp. 577-590
    • Tami, A.E.1    Schaffler, M.B.2    Knothe Tate, M.L.3
  • 36
    • 0036773777 scopus 로고    scopus 로고
    • Protein kinase C isotypes and their specific functions: Prologue
    • Ohno S, Nishizuka Y 2002 Protein kinase C isotypes and their specific functions: Prologue. J Biochem (Tokyo) 132:509-511.
    • (2002) J Biochem (Tokyo) , vol.132 , pp. 509-511
    • Ohno, S.1    Nishizuka, Y.2
  • 37
    • 0347623212 scopus 로고    scopus 로고
    • The role of PKCdelta and PKCepsilon in the neonatal rat colon in response to hypoxia challenge
    • Conte M, Soper B, Chang Q, Tepperman B 2004 The role of PKCdelta and PKCepsilon in the neonatal rat colon in response to hypoxia challenge. Pediatr Res 55:27-33.
    • (2004) Pediatr Res , vol.55 , pp. 27-33
    • Conte, M.1    Soper, B.2    Chang, Q.3    Tepperman, B.4
  • 38
    • 0030827291 scopus 로고    scopus 로고
    • Signal transduction of mechanical stimuli is dependent on microfilament integrity: Identification of osteopontin as a mechanically induced gene in osteoblasts
    • Toma CD, Ashkar S, Gray ML, Schaffer JL, Gerstenfeld LC 1997 Signal transduction of mechanical stimuli is dependent on microfilament integrity: Identification of osteopontin as a mechanically induced gene in osteoblasts. J Bone Miner Res 12:1626-1636.
    • (1997) J Bone Miner Res , vol.12 , pp. 1626-1636
    • Toma, C.D.1    Ashkar, S.2    Gray, M.L.3    Schaffer, J.L.4    Gerstenfeld, L.C.5
  • 39
    • 0036257365 scopus 로고    scopus 로고
    • Novel protein kinase C isoforms and mitogen-activated kinase kinase mediate phorbol ester-induced osteopontin expression
    • Chang PL, Tucker MA, Hicks PH, Prince CW 2002 Novel protein kinase C isoforms and mitogen-activated kinase kinase mediate phorbol ester-induced osteopontin expression. Int J Biochem Cell Biol 34:1142-1151.
    • (2002) Int J Biochem Cell Biol , vol.34 , pp. 1142-1151
    • Chang, P.L.1    Ma, T.2    Hicks, P.H.3    Prince, C.W.4
  • 40
    • 0346096818 scopus 로고    scopus 로고
    • Bryostatin-1: A novel PKC inhibitor in clinical development
    • Kortmansky J, Schwartz GK 2003 Bryostatin-1: A novel PKC inhibitor in clinical development. Cancer Invest 21:924-936.
    • (2003) Cancer Invest , vol.21 , pp. 924-936
    • Kortmansky, J.1    Schwartz, G.K.2
  • 41
    • 9144226837 scopus 로고    scopus 로고
    • A Phase II trial of aprinocarsen, an antisense oligonucleotide inhibitor of protein kinase C alpha, administered as a 21-day infusion to patients with advanced ovarian carcinoma
    • Advani R, Peethambaram P, Lum BL, Fisher GA, Hartmann L, Long HJ, Halsey J, Holmlund JT, Dorr A, Sikic BI 2004 A Phase II trial of aprinocarsen, an antisense oligonucleotide inhibitor of protein kinase C alpha, administered as a 21-day infusion to patients with advanced ovarian carcinoma. Cancer 100:321-326.
    • (2004) Cancer , vol.100 , pp. 321-326
    • Advani, R.1    Peethambaram, P.2    Lum, B.L.3    Fisher, G.A.4    Hartmann, L.5    Long, H.J.6    Halsey, J.7    Holmlund, J.T.8    Dorr, A.9    Sikic, B.I.10
  • 42
    • 25544461194 scopus 로고
    • Temporal nature of osteoclast resorption in response to disuse
    • Bain SD, Rubin CT 1990 Temporal nature of osteoclast resorption in response to disuse. J Bone Miner Res 5:S2;S217.
    • (1990) J Bone Miner Res , vol.5
    • Bain, S.D.1    Rubin, C.T.2
  • 43
    • 0018824101 scopus 로고
    • Studies of skeletal remodeling in aging men
    • Martin RB, Pickett JC, Zinaich S 1980 Studies of skeletal remodeling in aging men. Clin Orthop 149:268-282.
    • (1980) Clin Orthop , vol.149 , pp. 268-282
    • Martin, R.B.1    Pickett, J.C.2    Zinaich, S.3
  • 44
    • 0020549037 scopus 로고
    • Tibial changes in experimental disuse osteoporosis in the monkey
    • Young DR, Niklowitz WJ, Steele CR 1983 Tibial changes in experimental disuse osteoporosis in the monkey. Calcif Tissue Int 35:304-308.
    • (1983) Calcif Tissue Int , vol.35 , pp. 304-308
    • Young, D.R.1    Niklowitz, W.J.2    Steele, C.R.3
  • 46
    • 0033197546 scopus 로고    scopus 로고
    • Osteoclastogenesis is repressed by mechanical strain in an in vitro model
    • Rubin J, Fan X, Biskobing DM, Taylor WR, Rubin CT 1999 Osteoclastogenesis is repressed by mechanical strain in an in vitro model. J Orthop Res 17:639-645.
    • (1999) J Orthop Res , vol.17 , pp. 639-645
    • Rubin, J.1    Fan, X.2    Biskobing, D.M.3    Taylor, W.R.4    Rubin, C.T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.