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Volumn 31, Issue 2-3, 1999, Pages 55-64

Raf-1 activation stimulates proliferation and inhibits IGF-stimulated differentiation in L6A1 myoblasts

Author keywords

LY294002; MAP kinase; P70 S6 kinase; PD098059; PI 3 kinase; Signal transduction; Skeletal muscle; Raf 1:ER

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; CREATINE KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MYOGENIN; RAF PROTEIN; RAS PROTEIN; S6 KINASE; SOMATOMEDIN;

EID: 0032922703     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-978699     Document Type: Article
Times cited : (31)

References (59)
  • 1
    • 0019831207 scopus 로고
    • Effect of somatomedins and insulin on myoblast differentiation in vitro
    • 1. Ewton DZ, Florini JR. Effect of somatomedins and insulin on myoblast differentiation in vitro. Develop Biol 1981; 86: 31 -9
    • (1981) Develop Biol , vol.86 , pp. 31-39
    • Ewton, D.Z.1    Florini, J.R.2
  • 2
    • 0015124325 scopus 로고
    • Diffusion-mediated control of myoblast fusion
    • 2. Konigsberg IR. Diffusion-mediated control of myoblast fusion. Develop Biol 1971; 26: 133-52
    • (1971) Develop Biol , vol.26 , pp. 133-152
    • Konigsberg, I.R.1
  • 3
    • 0024580644 scopus 로고
    • Regulation of skeletal muscle satellite cell proliferation and differentiation by transforming growth factor-beta, insulin-like growth factor-I, and fibroblast growth factor
    • 3. Allen RE, Boxhorn LK. Regulation of skeletal muscle satellite cell proliferation and differentiation by transforming growth factor-beta, insulin-like growth factor-I, and fibroblast growth factor. J Cell Physiol 1989; 138: 311 -5
    • (1989) J Cell Physiol , vol.138 , pp. 311-315
    • Allen, R.E.1    Boxhorn, L.K.2
  • 4
    • 0020557702 scopus 로고
    • Preferential enhancement of myoblast differentiation by insulin-like growth factors (IGF-I and IGF-II) in primary cultures of chicken embryonic cells
    • 4. Schmid Ch, Steiner Th, Froesch ER. Preferential enhancement of myoblast differentiation by insulin-like growth factors (IGF-I and IGF-II) in primary cultures of chicken embryonic cells. FEBS Letters 1983; 161: 117-21
    • (1983) FEBS Letters , vol.161 , pp. 117-121
    • Schmid, Ch.1    Steiner, Th.2    Froesch, E.R.3
  • 5
    • 0023769829 scopus 로고
    • Control of myogenesis in the mouse myogenic C2 cell line by medium composition and by insulin: Characterization of permissive and inducible C2 myoblasts
    • 5. Pinset C, Montarras D, Chenevert J, Minty A, Barton P, Lauerent C, Gros F. Control of myogenesis in the mouse myogenic C2 cell line by medium composition and by insulin: characterization of permissive and inducible C2 myoblasts. Differentiation 1988; 38: 28-34
    • (1988) Differentiation , vol.38 , pp. 28-34
    • Pinset, C.1    Montarras, D.2    Chenevert, J.3    Minty, A.4    Barton, P.5    Lauerent, C.6    Gros, F.7
  • 6
    • 0028805138 scopus 로고
    • Opposing early and late effects of insulin-like growth factor I on differentiation and the cell cycle regulatory retinoblastoma protein in skeletal myoblasts
    • 6. Rosenthal SM, Cheng Z-Q. Opposing early and late effects of insulin-like growth factor I on differentiation and the cell cycle regulatory retinoblastoma protein in skeletal myoblasts. Proc Natl Acad Sci 1995; 92: 10307-11
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 10307-10311
    • Rosenthal, S.M.1    Cheng, Z.-Q.2
  • 7
    • 0029958679 scopus 로고    scopus 로고
    • Proliferation precedes differentiation in IGF-I-stimulated myogenesis
    • 7. Engert JC, Berglund EB, Rosenthal N. Proliferation precedes differentiation in IGF-I-stimulated myogenesis. J Cell Biol 1996; 135: 431-40
    • (1996) J Cell Biol , vol.135 , pp. 431-440
    • Engert, J.C.1    Berglund, E.B.2    Rosenthal, N.3
  • 8
    • 0031936895 scopus 로고    scopus 로고
    • Retrovirally mediated overexpression of insulin-like growth factor binding protein 4: Evidence that insulin-like growth factor is required for skeletal muscle differentiation
    • 8. Damon SE, Haugk KL, Birnbaum RS, Quinn LS. Retrovirally mediated overexpression of insulin-like growth factor binding protein 4: evidence that insulin-like growth factor is required for skeletal muscle differentiation. J Cell Physiol 1998; 175: 109-24
    • (1998) J Cell Physiol , vol.175 , pp. 109-124
    • Damon, S.E.1    Haugk, K.L.2    Birnbaum, R.S.3    Quinn, L.S.4
  • 9
    • 0027971736 scopus 로고
    • IGF-II is more active than IGF-I in stimulating L6A1 myogenesis: Greater mitogenic actions of IGF-I delay differentiation
    • 9. Ewton DZ, Roof SL, Magri KA, McWade FJ, Florini JR. IGF-II is more active than IGF-I in stimulating L6A1 myogenesis: greater mitogenic actions of IGF-I delay differentiation. J Cell Physiol 1994; 161: 277-84
    • (1994) J Cell Physiol , vol.161 , pp. 277-284
    • Ewton, D.Z.1    Roof, S.L.2    Magri, K.A.3    McWade, F.J.4    Florini, J.R.5
  • 10
    • 0030068744 scopus 로고    scopus 로고
    • Myogenin expression, cell cycle withdrawal, and phenotypic differentiation are temporally separable events that precede cell fusion upon moygenesis
    • 10. Andres V, Walsh K. Myogenin expression, cell cycle withdrawal, and phenotypic differentiation are temporally separable events that precede cell fusion upon moygenesis. J Cell Biol 1996; 132: 657-66
    • (1996) J Cell Biol , vol.132 , pp. 657-666
    • Andres, V.1    Walsh, K.2
  • 11
    • 0030934472 scopus 로고    scopus 로고
    • The mitogenic and myogenic actions of insulin-like growth factors utilize distinct signaling pathways
    • 11. Coolican SA, Samuel DS, Ewton DZ, McWade FJ, Florini JR. The mitogenic and myogenic actions of insulin-like growth factors utilize distinct signaling pathways. J Biol Chem 1997; 272: 12699-7 02
    • (1997) J Biol Chem , vol.272 , pp. 12699-12702
    • Coolican, S.A.1    Samuel, D.S.2    Ewton, D.Z.3    McWade, F.J.4    Florini, J.R.5
  • 13
    • 0028175091 scopus 로고
    • Raf meets ras: Completing the framework of a signal transduction pathway
    • 13. Avruch J, Zhang XF, Kryiakis JM. Raf meets Ras: completing the framework of a signal transduction pathway. Trends Biochem Sci 1994; 19: 279-83
    • (1994) Trends Biochem Sci , vol.19 , pp. 279-283
    • Avruch, J.1    Zhang, X.F.2    Kryiakis, J.M.3
  • 14
    • 0029935418 scopus 로고    scopus 로고
    • Regulation of transcription by MAP kinase cascades
    • 14. Treisman R. Regulation of transcription by MAP kinase cascades. Curr Opin Cell Biol 1996; 8: 205-15
    • (1996) Curr Opin Cell Biol , vol.8 , pp. 205-215
    • Treisman, R.1
  • 15
    • 0028272507 scopus 로고
    • Requirement for ras in Raf activation is overcome by targeting Raf to the plasma membrane
    • 15. Leevers SJ, Paterson HF, Marshall CJ. Requirement for ras in Raf activation is overcome by targeting Raf to the plasma membrane. Nature 1994; 369: 411 -4
    • (1994) Nature , vol.369 , pp. 411-414
    • Leevers, S.J.1    Paterson, H.F.2    Marshall, C.J.3
  • 17
    • 0029006126 scopus 로고
    • Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation
    • 17. Marais R, Light Y, Paterson HF, Marshall CJ. Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation. EMBO J 1995; 14: 3136-45
    • (1995) EMBO J , vol.14 , pp. 3136-3145
    • Marais, R.1    Light, Y.2    Paterson, H.F.3    Marshall, C.J.4
  • 18
    • 0030029343 scopus 로고    scopus 로고
    • Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylation
    • 18. Jelinek T, Dent P, Sturgill TW, Weber MJ. Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylation. Mol Cell Biol 1996; 16: 1027-34
    • (1996) Mol Cell Biol , vol.16 , pp. 1027-1034
    • Jelinek, T.1    Dent, P.2    Sturgill, T.W.3    Weber, M.J.4
  • 19
    • 0031054797 scopus 로고    scopus 로고
    • Negative modulation of membrane localization of the Raf-1 protein kinase by hyperphosphorylation
    • 19. Wartmann M, Hofer P, Turowski P, Saltiel AR, Haynes NE. Negative modulation of membrane localization of the Raf-1 protein kinase by hyperphosphorylation. J Biol Chem 1997; 272: 3915-23
    • (1997) J Biol Chem , vol.272 , pp. 3915-3923
    • Wartmann, M.1    Hofer, P.2    Turowski, P.3    Saltiel, A.R.4    Haynes, N.E.5
  • 20
    • 0028884033 scopus 로고
    • PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
    • 20. Alessi D, Cuenda A, Cohen P, Dudley D, Saltiel A. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 1995; 270: 27489-94
    • (1995) J Biol Chem , vol.270 , pp. 27489-27494
    • Alessi, D.1    Cuenda, A.2    Cohen, P.3    Dudley, D.4    Saltiel, A.5
  • 22
    • 0029906339 scopus 로고    scopus 로고
    • Oncogenic Raf-1 activates p70 S6 kinase via a mitogen-activated protein kinase-independent pathway
    • 22. Lenormand P, McMahon M, Pouyssegur J. Oncogenic Raf-1 activates p70 S6 kinase via a mitogen-activated protein kinase-independent pathway. J Biol Chem 1996; 271: 15762 -8
    • (1996) J Biol Chem , vol.271 , pp. 15762-15768
    • Lenormand, P.1    McMahon, M.2    Pouyssegur, J.3
  • 23
    • 0030871667 scopus 로고    scopus 로고
    • High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1
    • 23. Sewing A, Wiseman B, Lloyd AC, Land H. High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1. Mol Cell Biol 1997; 17: 5588-97
    • (1997) Mol Cell Biol , vol.17 , pp. 5588-5597
    • Sewing, A.1    Wiseman, B.2    Lloyd, A.C.3    Land, H.4
  • 24
    • 0030835430 scopus 로고    scopus 로고
    • Raf-induced proliferation or cell cycle arrest is determined by the level of Raf-1 activity with arrest mediated by p21Cip1
    • 24. Woods D, Parry D, Cherwinski H, Bosch E, Lees E, McMahon M. Raf-induced proliferation or cell cycle arrest is determined by the level of Raf-1 activity with arrest mediated by p21Cip1. Mol Cell Biol 1997; 17: 5598-6 11
    • (1997) Mol Cell Biol , vol.17 , pp. 5598-5611
    • Woods, D.1    Parry, D.2    Cherwinski, H.3    Bosch, E.4    Lees, E.5    McMahon, M.6
  • 25
    • 0028223704 scopus 로고
    • Dissociation between activation of Raf-1 kinase and the 42-kDa mitogen-activated protein kinase/90-kDa S6 kinase cascade in the insulin/Ras pathway of adipocyte differentiation in 3T3-L
    • 25. Porras A, Muszynski K, Rapp RR, Santos E. Dissociation between activation of Raf-1 kinase and the 42-kDa mitogen-activated protein kinase/90-kDa S6 kinase cascade in the insulin/Ras pathway of adipocyte differentiation in 3T3-L. J Biol Chem 1994; 269: 12741 -8
    • (1994) J Biol Chem , vol.269 , pp. 12741-12748
    • Porras, A.1    Muszynski, K.2    Rapp, R.R.3    Santos, E.4
  • 26
    • 0027385030 scopus 로고
    • Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human Raf-1 protein kinase
    • 26. Samuels ML, Weber MJ, Bishop JM, McMahon M. Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human Raf-1 protein kinase. Mol Cell Biol 1993; 13: 6241-52
    • (1993) Mol Cell Biol , vol.13 , pp. 6241-6252
    • Samuels, M.L.1    Weber, M.J.2    Bishop, J.M.3    McMahon, M.4
  • 27
    • 0024465702 scopus 로고
    • Assay of creatine kinase in microtiter plates using thio-NAD to allow monitoring at 405 nm
    • 27. Florini JR. Assay of creatine kinase in microtiter plates using thio-NAD to allow monitoring at 405 nm. Anal Biochem 1989; 182: 399-4 04
    • (1989) Anal Biochem , vol.182 , pp. 399-404
    • Florini, J.R.1
  • 28
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during assembly of the head
    • 28. Laemmli UK. Cleavage of structural proteins during assembly of the head. Nature 1970; 227: 680 -5
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 29
    • 0030881165 scopus 로고    scopus 로고
    • Mutations of critical amino acids affect the biological and biochemical properties of oncogenic A-Raf and Raf-1
    • 29. Bosch E, Cherwinski H, Peterson D, McMahon M. Mutations of critical amino acids affect the biological and biochemical properties of oncogenic A-Raf and Raf-1. Oncogene 1997; 15: 1021-33
    • (1997) Oncogene , vol.15 , pp. 1021-1033
    • Bosch, E.1    Cherwinski, H.2    Peterson, D.3    McMahon, M.4
  • 30
    • 0028877441 scopus 로고
    • Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells
    • 30. Pritchard CA, Michael SL, Bosch E, McMahon M. Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells. Mol Cell Biol 1995; 15: 6430-42
    • (1995) Mol Cell Biol , vol.15 , pp. 6430-6442
    • Pritchard, C.A.1    Michael, S.L.2    Bosch, E.3    McMahon, M.4
  • 31
    • 0028937039 scopus 로고
    • Insulin-like growth factor binding proteins -4, -5, and -6 may play specialized roles during L6 myoblast proliferation and differentiation
    • 31. Ewton DZ, Florini JR. Insulin-like growth factor binding proteins -4, -5, and -6 may play specialized roles during L6 myoblast proliferation and differentiation. J Endocrinol 1995; 144; 539-53
    • (1995) J Endocrinol , vol.144 , pp. 539-553
    • Ewton, D.Z.1    Florini, J.R.2
  • 32
    • 0025836395 scopus 로고
    • IGF-I stimulates terminal myogenic differentiation by induction of myogenin gene expression
    • 32. Florini JR, Ewton DZ, Roof SL. IGF-I stimulates terminal myogenic differentiation by induction of myogenin gene expression. Molecular Endocrinol 1991a; 5: 718-24
    • (1991) Molecular Endocrinol , vol.5 , pp. 718-724
    • Florini, J.R.1    Ewton, D.Z.2    Roof, S.L.3
  • 33
    • 0031917412 scopus 로고    scopus 로고
    • Insulin-like growth factors require phosphatidylinositol 3-kinase to signal myogenesis: Dominant negative p85 expression blocks differentiation of L6E9 muscle cells
    • 33. Kaliman P, Canico J, Shepherd PR, Beeton CA, Testar X, Palacin M, Zorzano A. Insulin-like growth factors require phosphatidylinositol 3-kinase to signal myogenesis: dominant negative p85 expression blocks differentiation of L6E9 muscle cells. Mol Endocrinol 1997; 12: 66-77
    • (1997) Mol Endocrinol , vol.12 , pp. 66-77
    • Kaliman, P.1    Canico, J.2    Shepherd, P.R.3    Beeton, C.A.4    Testar, X.5    Palacin, M.6    Zorzano, A.7
  • 34
    • 0027496895 scopus 로고
    • Mice carrying null mutations of the genes encoding insulin-like growth factors I (IGF-I) and type 1 IGF receptor (IGF1r)
    • 34. Liu J-L, Baker J, Perkins AS, Robertson EJ, Efstratiadis A. Mice carrying null mutations of the genes encoding insulin-like growth factors I (IGF-I) and type 1 IGF receptor (IGF1r). Cell 1993; 75: 59-72
    • (1993) Cell , vol.75 , pp. 59-72
    • Liu, J.-L.1    Baker, J.2    Perkins, A.S.3    Robertson, E.J.4    Efstratiadis, A.5
  • 37
    • 0027297310 scopus 로고
    • Myogenin gene disruption results in perinatal lethality because of severe muscle defect
    • 37. Nabeshima Y, Hanaoka K, Hayasaka M, Esumi E, Li S, Nonaka I, Nabeshima Y. Myogenin gene disruption results in perinatal lethality because of severe muscle defect. Nature 1993; 364: 532 -5
    • (1993) Nature , vol.364 , pp. 532-535
    • Nabeshima, Y.1    Hanaoka, K.2    Hayasaka, M.3    Esumi, E.4    Li, S.5    Nonaka, I.6    Nabeshima, Y.7
  • 38
    • 0029741689 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase inhibitors block differentiation of skeletal muscle cells
    • 38. Kaliman P, Vinals F, Textar X, Palacin M, Zorzano A. Phosphatidylinositol 3-kinase inhibitors block differentiation of skeletal muscle cells. J Biol Chem 1996; 271: 19146-51
    • (1996) J Biol Chem , vol.271 , pp. 19146-19151
    • Kaliman, P.1    Vinals, F.2    Textar, X.3    Palacin, M.4    Zorzano, A.5
  • 39
    • 0030868467 scopus 로고    scopus 로고
    • Wortmannin inhibits IGF-dependent differentiation in the mouse myogenic cell line C2
    • 39. Pinset C, Garcia A, Rousse S, Dubois C, Montarras D. Wortmannin inhibits IGF-dependent differentiation in the mouse myogenic cell line C2. Compt Rendu Acad Sci Paris 1997; 320: 367-74
    • (1997) Compt Rendu Acad Sci Paris , vol.320 , pp. 367-374
    • Pinset, C.1    Garcia, A.2    Rousse, S.3    Dubois, C.4    Montarras, D.5
  • 40
    • 0025979335 scopus 로고
    • Raf-1 protein kinase is required for growth of induced NIH/3T3 cells
    • 40. Kolch W, Heidecker G, Lloyd P, Rapp UR. Raf-1 protein kinase is required for growth of induced NIH/3T3 cells. Nature 1991; 349: 426 -8
    • (1991) Nature , vol.349 , pp. 426-428
    • Kolch, W.1    Heidecker, G.2    Lloyd, P.3    Rapp, U.R.4
  • 41
    • 0027237273 scopus 로고
    • A dominant negative mutant of Raf blocks mitogen-activated protein kinase activation by growth factors and oncogenic p21 ras
    • 41. Schaap D, van der Wal J, Howe LR, Marshall CJ, van Blitterswijk WJ. A dominant negative mutant of Raf blocks mitogen-activated protein kinase activation by growth factors and oncogenic p21 ras. J Biol Chem 1993; 268: 20232 -6
    • (1993) J Biol Chem , vol.268 , pp. 20232-20236
    • Schaap, D.1    Van Der Wal, J.2    Howe, L.R.3    Marshall, C.J.4    Van Blitterswijk, W.J.5
  • 42
    • 0028109683 scopus 로고
    • Inhibition of PDGF and EGF-mediated mitogenesis and signaling in 3T3 cells expressing DRaf-1:ER, an estradiol-regulated form of Raf-1
    • 42. Samuels ML, McMahon M. Inhibition of PDGF and EGF-mediated mitogenesis and signaling in 3T3 cells expressing DRaf-1:ER, an estradiol-regulated form of Raf-1. Mol Cell Biol 1994; 14: 7855-66
    • (1994) Mol Cell Biol , vol.14 , pp. 7855-7866
    • Samuels, M.L.1    McMahon, M.2
  • 43
    • 0024370528 scopus 로고
    • Transformation by activated RAS or FOS prevents myogenesis by inhibiting expression of MyoD1
    • 43. Lassar AB, Thayer MJ, Overell RW, Weintraub H. Transformation by activated RAS or FOS prevents myogenesis by inhibiting expression of MyoD1. Cell 1989; 58: 659-67
    • (1989) Cell , vol.58 , pp. 659-667
    • Lassar, A.B.1    Thayer, M.J.2    Overell, R.W.3    Weintraub, H.4
  • 44
    • 0023354739 scopus 로고
    • The oncogenic forms of N-ras or H-ras prevent skeletal myoblast differentiation
    • 44. Olson EN, Spizz G, Tainsky MA. The oncogenic forms of N-ras or H-ras prevent skeletal myoblast differentiation. Mol Cell Biol 1987; 7: 2104-11
    • (1987) Mol Cell Biol , vol.7 , pp. 2104-2111
    • Olson, E.N.1    Spizz, G.2    Tainsky, M.A.3
  • 45
    • 0023760131 scopus 로고
    • Dexamethasone-dependent inhibition of differentiation of C2 myoblasts bearing steroid-inducible N-ras oncogenes
    • 45. Gossett LA, Zhang W, Olson EN. Dexamethasone-dependent inhibition of differentiation of C2 myoblasts bearing steroid-inducible N-ras oncogenes. J Cell Biol 1988; 106: 2127-38
    • (1988) J Cell Biol , vol.106 , pp. 2127-2138
    • Gossett, L.A.1    Zhang, W.2    Olson, E.N.3
  • 46
    • 0024570217 scopus 로고
    • A ras-dependent pathway abolishes activity of a muscle-specific enhancer upstream from the muscle creatine kinase gene
    • 46. Sternberg EA, Spizz G, Perry ME, Olson EN. A ras-dependent pathway abolishes activity of a muscle-specific enhancer upstream from the muscle creatine kinase gene. Mol Cell Biol 1989; 9: 594-6 01
    • (1989) Mol Cell Biol , vol.9 , pp. 594-601
    • Sternberg, E.A.1    Spizz, G.2    Perry, M.E.3    Olson, E.N.4
  • 47
    • 0024560727 scopus 로고
    • Inhibition of myogenic differentiation by the H-ras oncogene is associated with the down regulation of the myoD1 gene
    • 47. Konieczny SF, Drobes BL, Menke SL, Taparowsky EJ. Inhibition of myogenic differentiation by the H-ras oncogene is associated with the down regulation of the myoD1 gene. Oncogene 1989; 4: 473-81
    • (1989) Oncogene , vol.4 , pp. 473-481
    • Konieczny, S.F.1    Drobes, B.L.2    Menke, S.L.3    Taparowsky, E.J.4
  • 48
    • 0025993772 scopus 로고
    • Spontaneous" differentiation of skeletal myoblasts is controlled by autocrine secretion of insulin-like growth factor-II
    • 48. Florini J, Magri K, Ewton D, James P, Grindstaff K, Rotwein P. "Spontaneous" differentiation of skeletal myoblasts is controlled by autocrine secretion of insulin-like growth factor-II. J Biol Chem 1991; 266: 15917-23
    • (1991) J Biol Chem , vol.266 , pp. 15917-15923
    • Florini, J.1    Magri, K.2    Ewton, D.3    James, P.4    Grindstaff, K.5    Rotwein, P.6
  • 50
    • 0031058756 scopus 로고    scopus 로고
    • Distinct signaling pathways regulate transformation and inhibition of skeletal muscle differentiation by oncogenic Ras
    • 50. Weyman CM, Ramocki MB, Taparowsky EJ, Wolfman A. Distinct signaling pathways regulate transformation and inhibition of skeletal muscle differentiation by oncogenic Ras. Oncogene 1997; 14: 697-7 04
    • (1997) Oncogene , vol.14 , pp. 697-704
    • Weyman, C.M.1    Ramocki, M.B.2    Taparowsky, E.J.3    Wolfman, A.4
  • 51
    • 0030989152 scopus 로고    scopus 로고
    • Signaling throught mitogen-activated protein kinase and rac/Rho does not duplicate the effects of activated ras on skeletal myogenesis
    • 51. Ramocki MB, Johnson SE, White MA, Ashendel CL, Konieczny SF, Taparowsky EJ. Signaling throught mitogen-activated protein kinase and rac/Rho does not duplicate the effects of activated Ras on skeletal myogenesis. Mol Cell Biol 1997; 17: 3547-55
    • (1997) Mol Cell Biol , vol.17 , pp. 3547-3555
    • Ramocki, M.B.1    Johnson, S.E.2    White, M.A.3    Ashendel, C.L.4    Konieczny, S.F.5    Taparowsky, E.J.6
  • 52
    • 0001632060 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase activation is not necessary for, but antagonizes, 3T3-L1 adipocytic differentiation
    • 52. De Mora JF, Porras A, Ahn N, Santos E. Mitogen-activated protein kinase activation is not necessary for, but antagonizes, 3T3-L1 adipocytic differentiation. Mol Cell Biol 1997; 17: 6068-75
    • (1997) Mol Cell Biol , vol.17 , pp. 6068-6075
    • De Mora, J.F.1    Porras, A.2    Ahn, N.3    Santos, E.4
  • 53
    • 0030722189 scopus 로고    scopus 로고
    • Regulation of distinct stages of skeletal muscle differentiation by mitogen-activated protein kinases
    • 53. Bennett AM, Tonks NK. Regulation of distinct stages of skeletal muscle differentiation by mitogen-activated protein kinases. Science 1997; 278: 1288-91
    • (1997) Science , vol.278 , pp. 1288-1291
    • Bennett, A.M.1    Tonks, N.K.2
  • 54
    • 0030833040 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase-1 and -2 respond differently to mitogenic and differentiative signaling pathways in myoblasts
    • 54. Sarbassov DD, Jones LB, Peterson CA. Extracellular signal-regulated kinase-1 and -2 respond differently to mitogenic and differentiative signaling pathways in myoblasts. Mol Endocrinol 1997; 11: 2038-20 47
    • (1997) Mol Endocrinol , vol.11 , pp. 2038-2047
    • Sarbassov, D.D.1    Jones, L.B.2    Peterson, C.A.3
  • 56
    • 0028270718 scopus 로고
    • Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum and TPA requires raf and is necessary for transformation
    • 56. Troppmair J, Bruder JT, Munoz H, Lloyd PA, Kyriakis J, Banerjee P, Avruch J, Rapp UR. Mitogen-activated protein kinase/Extracellular signal-regulated protein kinase activation by oncogenes, serum and TPA requires Raf and is necessary for transformation. J Biol Chem 1994; 269: 7030 -5
    • (1994) J Biol Chem , vol.269 , pp. 7030-7035
    • Troppmair, J.1    Bruder, J.T.2    Munoz, H.3    Lloyd, P.A.4    Kyriakis, J.5    Banerjee, P.6    Avruch, J.7    Rapp, U.R.8
  • 58
    • 0028863505 scopus 로고
    • Interactions between Ras and Raf: Key regulatory proteins in cellular transformation
    • 58. Marshall M. Interactions between Ras and Raf: Key regulatory proteins in cellular transformation. Mol Reproduct Devel 1995; 42: 493 -9
    • (1995) Mol Reproduct Devel , vol.42 , pp. 493-499
    • Marshall, M.1
  • 59
    • 0032898811 scopus 로고    scopus 로고
    • Variation among cell types in the signaling pathways by which IGF-I stimulates specific cellular responses
    • 59. Petley T, Graff K, Jiang W, Yang H, Florini J. Variation among cell types in the signaling pathways by which IGF-I stimulates specific cellular responses. Horm Metab Res 1999; 31: 70 -6
    • (1999) Horm Metab Res , vol.31 , pp. 70-76
    • Petley, T.1    Graff, K.2    Jiang, W.3    Yang, H.4    Florini, J.5


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