Pancreatic stellate cells can form new β-like cells

Biochemical Journal

Volumn 421, Issue 2, 2009, Pages

  Docherty, Kevin ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Cell therapy; Diabetes mellitus; Islet of Langerhans; Pancreatic stem cell

Indexed keywords

ALTERNATIVE SOURCE; CELL MARKERS; CELL POPULATIONS; CELL THERAPY; DIABETES MELLITUS; EMBRYONIC STEMS; EX-VIVO; EXTRACELLULAR MATRICES; GROWTH FACTOR; IN-SITU; ISLET OF LANGERHANS; PANCREATIC CELLS; PANCREATIC STEM CELL; PHENOTYPIC MARKERS; REGENERATIVE MEDICINE; REPLACEMENT STRATEGY; STELLATE CELLS; STEM CELL; TYPE-2 DIABETES;

AMINES; CELL MEMBRANES; CELL PROLIFERATION; GLUCOSE; INSULIN; MONOLAYERS; SELENIUM; TISSUE;

CELL CULTURE;

EXENDIN 4; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; INSULIN; SELENIUM; TRANSFERRIN;

ADULT STEM CELL; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CELL POPULATION; CELL RENEWAL; CELL THERAPY; CELL TRANSDIFFERENTIATION; DIABETES MELLITUS; EXTRACELLULAR MATRIX; FIBROBLAST; HUMAN; INSULIN RELEASE; NONHUMAN; ORGANOGENESIS; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; STELLATE CELL;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; HUMANS; INSULIN-SECRETING CELLS; MICE; PANCREAS; RATS; STEM CELLS;

RATTUS;

EID: 67650914869     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20090779     Document Type: Article

References (21)

1. Bonner-Weir, S., Inada, A., Yatoh, S., Li, W. C., Aye, T., Toschi, E. and Sharma, A. (2008) Transdifferentiation of pancreatic ductal cells to endocrine beta-cells. Biochem. Soc. Trans. 36, 353-356
2. Wild, S., Roglic, G., Green, A., Sicree, R. and King, H. (2004) Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 27, 1047-1053
3. Bernardo, A. S., Hay, C. W. and Docherty, K. (2008) Pancreatic transcription factors and their role in the birth, life and survival of the pancreatic beta cell. Mol. Cell. Endocrinol. 294, 1-9
4. Zhou, Q., Law, A. C., Rajagopal, J., Anderson, W. J., Gray, P. A. and Melton, D. A. (2007) A multipotent progenitor domain guides pancreatic organogenesis. Dev. Cell 13, 103-114
5. Bhagwandin, V. J. and Shay, J. W. (2009) Pancreatic cancer stem cells: fact or fiction? Biochim. Biophys. Acta 1792, 248-259
6. Baetge, E. E. (2008) Production of beta-cells from human embryonic stem cells. Diabetes Obes. Metab. 10 (Suppl. 4), 186-194
7. Dor, Y. (2006) Beta-cell proliferation is the major source of new pancreatic beta cells. Nat. Clin. Pract. Endocrinol. Metab. 2, 242-243
8. Teta, M., Rankin, M. M., Long, S. Y., Stein, G. M. and Kushner, J. A. (2007) Growth and regeneration of adult beta cells does not involve specialized progenitors. Dev. Cell 12, 817-826
9. Meier, J. J., Butler, A. E., Saisho, Y., Monchamp, T., Galasso, R., Bhushan, A., Rizza, R. A. and Butler, P. C. (2008) Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans. Diabetes 57, 1584-1594
10. Stanger, B. Z., Tanaka, A. J. and Melton, D. A. (2007) Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver. Nature 445, 886-891
11. Inada, A., Nienaber, C., Katsuta, H., Fujitani, Y., Levine, J., Morita, R., Sharma, A. and Bonner-Weir, S. (2008) Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth. Proc. Natl. Acad. Sci. U.S.A. 105, 19915-19919
12. Xu, X., D'Hoker, J., Stange, G., Bonne, S., De Leu, N., Xiao, X., Van de Casteele, M., Mellitzer, G., Ling, Z., Pipeleers, D. et al. (2008) Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas. Cell 132, 197-207
13. Baeyens, L. and Bouwens, L. (2008) Can beta-cells be derived from exocrine pancreas? Diabetes Obes. Metab. 10 (Suppl. 4), 170-178
14. Sahu, S., Tosh, D. and Hardikar, A. (2009) New sources of beta-cells for treating diabetes, J. Endocrinol., doi:10.1677/JOE-09-0097
15. Mato, E., Lucas, M., Petriz, J., Gomis, R. and Novials, A. (2009) Identification of pancreatic stellate cell population with properties of progenitor cells: new role for stellate cells in pancreas. Biochem. J. 421, 181-191
16. Omary, M. B., Lugea, A., Lowe, A. W. and Pandol, S. J. (2007) The pancreatic stellate cell: a star on the rise in pancreatic diseases. J. Clin. Invest. 117, 50-59
17. Guo, T. and Hebrok, M. (2009) Stem cells to pancreatic beta-cells: new sources for diabetes cell therapy. Endocr. Rev. 30, 214-227
18. Lechner, A., Leech, C. A., Abraham, E. J., Nolan, A. L. and Habener, J. F. (2002) Nestin-positive progenitor cells derived from adult human pancreatic islets of Langerhans contain side population (SP) cells defined by expression of the ABCG2 (BCRP1) ATP-binding cassette transporter. Biochem. Biophys. Res. Commun. 293, 670-674
19. Zhao, M., Amiel, S. A., Christie, M. R., Muiesan, P., Srinivasan, P., Littlejohn, W., Rela, M., Arno, M., Heaton, N. and Huang, G. C. (2007) Evidence for the presence of stem cell-like progenitor cells in human adult pancreas. J. Endocrinol. 195, 407-414
20. Suzuki, A., Nakauchi, H. and Taniguchi, H. (2004) Prospective isolation of multipotent pancreatic progenitors using flow-cytometric cell sorting. Diabetes 53, 2143-2152
21. Zaret, K. S. and Grompe, M. (2008) Generation and regeneration of cells of the liver and pancreas. Science 322, 1490-1494