Genomic and phenotypic analysis reveals a key role for CCN1 (CYR61) in BAG3 - Modulated adhesion and invasion

Journal of Pathology

Volumn 218, Issue 4, 2009, Pages 495-504

  Kassis, Jareer N ^a,c   Virador, Victoria M ^a   Guancial, Elizabeth A ^a   Kimm, Daniel ^a   Ho, Allen S ^a   Mishra, Mark ^a   Chuang, Eric Y ^a   Cook, John ^a   Gius, David ^a   Kohn, Elise C ^a,b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b MSC 1906 ^*  (United States)

^c Transtech Pharma   (United States)

Author keywords

Adhesion; BAG3; CCN1; Cyr61; Genomic analysis; Integrin engagement

Indexed keywords

BETA1 INTEGRIN; CARRIER PROTEIN; COLLAGEN TYPE 4; CYSTEINE RICH PROTEIN 61; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MATRIGEL; PROLINE; PROTEIN BAG3; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL; CELL ADHESION; CELL INVASION; CONTROLLED STUDY; DNA BINDING; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; GENOME ANALYSIS; HELA CELL; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN TARGETING; UPREGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANTIGENS, CD29; CELL ADHESION; CELL LINE, TUMOR; COLLAGEN; CYSTEINE-RICH PROTEIN 61; DRUG COMBINATIONS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION PROFILING; GENE SILENCING; GENOMICS; HELA CELLS; HUMANS; LAMININ; NEOPLASM INVASIVENESS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHORYLATION; PROTEOGLYCANS; RNA, MESSENGER; UP-REGULATION;

EID: 67650908098     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2557     Document Type: Article

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