Potent antimalarial activity of newly synthesized substituted chalcone analogs in vitro

Medicinal Chemistry Research

Volumn 18, Issue 6, 2009, Pages 407-420

  Awasthi, Satish K ^a   Mishra, Nidhi ^a   Kumar, Brajesh ^a   Sharma, Manish ^a   Bhattacharya, Amit ^a   Mishra, Lokesh C ^a   Bhasin, Virendra K ^a  

^a UNIVERSITY OF DELHI   (India)

Author keywords

Chalcones; In vitro antimalarial activity; Plasmodium falciparum; Synthesis

Indexed keywords

1 (4 IMIDAZOL 1 YL PHENYL) 3 (3,4,5, TRIMETHOXYPHENYL)PROP 2 EN 1 ONE; 1 (4 PIPERAZIN 1 YL PHENYL) 3 (3,4,5 TRIMETHOXYPHENYL)PROP 2 EN 1 ONE; 1 (4 PYRROL 1 YL PHENYL) 3 (3,4,5 TRIMETHOXYPHENYL)PROP 2 EN 1 ONE; 1 (4 PYRROLIDIN 1 YL PHENYL) 3 (3,4,5 TRIMETHOXYPHENYL)PROP 2 EN 1 ONE; 3 (2 CHLOROQUINOLIN 3 YL) 1 (4 MORPHOLIN 4 YL PHENYL)PROP 2 EN 1 ONE; 3 (3,4 DIMETHEOXYPHENYL) 1 (4 PIPERIDIN 1 YL PHENYL)PROP 2 EN ONE; 3 (3,5 DIMETHOXYPHENYL) 1 (4 (PYRROLIDIN 1 YL PHENYL)PROP 2 EN 1 ONE; 3 (4 METHOXYPHENYL) 1 (4 [1,2,4]TRIAZOL 1 YL PHENYL)PROP 2 EN 1 ONE; 3 (4 METHOXYPHENYL) 1 (4 MORPHOLIN 4 YL PHENYL)PROP 2 EN 1 ONE; 3 (4 METHOXYPHENYL) 1 (4 PYRROL 1 YL PHENYL)PROP 2 EN 1 ONE; 3 (4 METHOXYPHENYL) 1 (4 PYRROLIDIN 1 YL PHENYL)PROP 2 EN 1 ONE; ANTIMALARIAL AGENT; ARTEMISININ; CHALCONE DERIVATIVE; LICOCHALCONE A; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROPHOBICITY; IC 50; IN VITRO STUDY; INFRARED SPECTROSCOPY; NONHUMAN; PLASMODIUM FALCIPARUM; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 67650759608     PISSN: 10542523     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00044-008-9137-9     Document Type: Article

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