Proteomics analysis of two mice hepatocarcinoma ascites syngeneic cell lines with high and low lymph node metastasis rates provide potential protein markers for tumor malignancy attributes to lymphatic metastasis

Proteomics

Volumn 9, Issue 12, 2009, Pages 3285-3302

  Sun, Ming Zhong ^a   Liu, Shuqing ^a   Tang, Jianwu ^a   Wang, Zhiqiang ^a   Gong, Xiaolin ^a   Sun, Chengrong ^a   Greenaway, Frederic ^b  

^a DALIAN MEDICAL UNIVERSITY   (China)

^b CLARK UNIVERSITY   (United States)

Author keywords

2 D DIGE; Lymphatic metastasis; Protein profiling; Proteomics; Tumor malignancy

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; PROTEIN; SHORT HAIRPIN RNA; SYNEXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; ASCITES CELL; BIOINFORMATICS; CANCER CELL CULTURE; CELL CYCLE; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; FLOW CYTOMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CELL CARCINOMA; LYMPH NODE; LYMPH NODE METASTASIS; LYMPHATIC SYSTEM; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIMARY TUMOR; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; STOMACH CANCER; TUMOR GROWTH; TWO DIMENSIONAL GEL ELECTROPHORESIS; WESTERN BLOTTING;

ANIMALS; ANNEXIN A7; ASCITES; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL MOVEMENT; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GENE EXPRESSION PROFILING; HUMANS; LIVER NEOPLASMS, EXPERIMENTAL; LYMPH NODES; LYMPHATIC METASTASIS; MICE; NEOPLASM PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEOMICS; RNA INTERFERENCE; RNA, MESSENGER; STOMACH NEOPLASMS; TANDEM MASS SPECTROMETRY; TUMOR MARKERS, BIOLOGICAL;

MUS;

EID: 67650756555     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.200701002     Document Type: Article

References (75)

1. Jackson, D. G., Biology of the lymphatic marker LYVE-1 and applications in research into lymphatic trafficking and lymphangiogenesis. APMIS 2004, 112, 526-538.
2. Pepper, M. S., Skobe, M., Lymphatic endothelium: morphological, molecular and functional properties. J. Cell Biol. 2003, 163, 209-213.
3. Nisato, R. E., Tille, J.-C., Pepper, M. S., Lymphangiogenesis and tumor metastasis. Thromb. Haemost. 2003, 90, 591-597.
4. Harrell, M. I., Iritani, B. M., Ruddell, A., Tumor-induced sentinel lymph node lymphangiogenesis and increased lymph flow precede melanoma metastasis. Am. J. Pathol. 2007, 170, 774-786.
5. Marchiole, P., Buénerd, A., Benchaib, M., Nezhat, K. et al., Clinical significance of lympho vascular space involvement and lymph node micrometastases in early-stage cervical cancer: a retrospective case-control surgico-pathological study. Gynecol. Oncol. 2005, 97, 727-732.
6. Yonemura, Y., Endou, Y., Tabachi, K., Kawamura, T. et al., Evaluation of lymphatic invasion in primary gastric cancer by a new monoclonal antibody, D2-40. Hum. Pathol. 2006, 37, 1193-1199.
7. Saharinen, P., Tammela, T., Karkkainen, M. J., Alitalo, K., Lymphatic vasculature: development, molecular regulation and role in tumor metastasis and inflammation. Trends Immunol. 2004, 25, 387-395.
8. Björndahl, M. A., Cao, R., Burton, J. B., Brakenhielm, E. et al., Vascular endothelial growth factor-a promotes peritumoral lymphangiogenesis and lymphatic metastasis. Cancer Res. 2005, 65, 9261-9268.
9. Audet, N., Beasley, N. J., MacMillan, C., Jackson, D. G. et al., Lymphatic vessel density, nodal metastases, and prognosis in patients with head and neck cancer. Arch. Otolaryngol. Head Neck Surg. 2005, 131, 1065-1070.
10. Kopfstein, L., Veikkola, T., Djonov, V. G., Baeriswyl, V. et al., Distinct roles of vascular endothelial growth factor-D in lymphangiogenesis and metastasis. Am. J. Pathol. 2007, 170, 1348-1361.
11. He, Y., Rajantie, I., Pajusola, K., Jeltsch, M. et al., Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels. Cancer Res. 2005, 65, 4739-4746.
12. Shayan, R., Achen, M. G., Stacker, S. A., Lymphatic vessels in cancer metastasis: bridging the gaps. Carcinogenesis 2006, 27, 1729-1738.
13. He, Y., Karpanen, T., Alitalo, K., Role of lymphangiogenic factors in tumor metastasis. Biochim. Biophys. Acta 2004, 1654, 3-12.
14. Achen, M. G., Mann, G. B., Stacker, S. A., Targeting lymphangiogenesis to prevent tumour metastasis. Br. J. Cancer 2006, 94, 1355-1360
15. Sahni, D., Robson, A., Orchard, G., Szydlo, R. et al., The use of LYVE-1 antibody for detecting lymphatic involvement in patients with malignant melanoma of known sentinel node status. J. Clin. Pathol. 2005, 58, 715-721.
16. Franchi, A., Gallo, O., Massi, D., Baroni, G., Santucci, M., Tumor lymphangiogenesis in head and neck squamous cell carcinoma: a morphometric study with clinical correlations. Cancer 2004, 101, 973-978.
17. Song, B., Wang, B., Cui, X., Li, X. et al., Comparative analysis of lymphatic metastasis-associated genes in mouse hepatocellular carcinoma cell lines with different metastatic potential. Chin. J. Cancer Res. 2006, 18, 26-31.
18. Cui, X., Tang, J., Hou, L., Song, B., Ban, L., Identification of differentially expressed genes in mouse hepatocarcinoma ascites cell line with low potential of lymphogenous metastasis. World J. Gastroenterol. 2006, 12, 6893-6897.
19. Song, B., Tang, J., Wang, B., Cui, X. et al., Identify lymphatic metastasis-associated genes in mouse hepatocarcinoma cell lines using gene chip. World J. Gastroenterol. 2005, 11, 1463-1472.
20. Hou, L., Li, Y., Jia, Y., Wang, B. et al., Molecular mechanism about lymphogenous metastasis of hepatocarcinoma cells in mice. World J. Gastroenterol. 2001, 7, 532-536.
21. Li, H., Ling, M., Xie, Y., Xie, H., Establishment of a lymph node metastatic model of mouse hepatocellular carcinoma Hca-F cells in C3H/Hej mice. Oncol. Res. 1998, 10, 569-573.
22. Zhou, H., Li, J., Wang, S., Wang, H. et al., Divergent expression and roles for caveolin-1 in mouse hepatocarcinoma cell lines with varying invasive ability. Biochem. Biophys. Res. Commun. 2006, 345, 486-494.
23. Jia, L., Wang, S., Zhou, H., Cao, J. et al., Caveolin-1 up-regulates CD147 glycosylation and the invasive capability of murine hepatocarcinoma cell lines. Int. J. Biochem. Cell Biol. 2006, 38, 1584-1593.
24. Alban, A., David, S. O., Bjorkesten, L., Andersson, C. et al., A novel experimental design for comparative two-dimensional gel analysis: two-dimensional difference gel electrophoresis incorporating a pooled internal standard. Proteomics 2003, 3, 36-44.
25. Richard, E., Monteoliva, L., Juarez, S., Pérez, B. et al., Quantitative analysis of mitochondrial protein expression in methylmalonic acidemia by two-dimensional difference gel electrophoresis. J. Proteome Res. 2006, 5, 1602-1610.
26. Liu, S., Sun, M. -Z., Greenaway, F. T., A novel plasminogen activator from Agkistrodon blomhoffii ussurensis venom (ABUSV-PA): purification and characterization. Biochem. Biophys. Res. Commun. 2006, 348, 1279-1287.
27. 2+ on function and structure. Biochim. Biophys. Acta 2006, 1764, 1340-1348.
28. Liu, S., Sun, M. - Z., Sun, C., Zhao, B., Greenaway, F. T. et al., A novel serine protease from the snake venom of Agkistrodon blomhoffii ussurensis. Toxicon 2008, 52, 760-768.
29. America, A. H. P., Cordewener, J. H. G., van Geffen, M. H. A., Lommen, A. et al., Alignment and statistical difference analysis of complex peptide data sets generated by multidimensional LC-MS. Proteomics 2006, 6, 641-653.
30. Zheng, L., Liu, S., Sun, M. -Z., Chang, J. et al., Proteomic analysis of retinal injury due to ischemia and reperfusion: alterations in the glycolytic pathway. Proteomics 2009, 9, 1869-1882.
31. Johansson, C., Samskog, J., Sundstrom, L., Wadensten, H. et al., Differential expression analysis of Escherichia coli proteins using a novel software for relative quantitation of LC-MS/MS data. Proteomics 2006, 6, 4475-4485.
32. Crockett, D. K., Fillmore, G. C., Elenitoba-Johnson, K. S., Lim, M. S., Analysis of phosphatase and tensin homolog tumor suppressor interacting proteins by in vitro and in silico proteomics. Proteomics 2005, 5, 1650-1662.
33. Eng, J., McCormack, A. L., Yates, J. R., An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. J. Am. Soc. Mass Spectrom. 1994, 5, 976-989.
34. Mi, H., Guo, N., Kejariwal, A., Thomas, P. D., PANTHER version 6: protein sequence and function evolution data with expanded representation of biological pathways. Nucleic Acids Res. 2007, 35, D247-D252.
35. Thomas, P. D., Campbell, M. J., Kejariwal, A., Mi, H. et al., PANTHER: a library of protein families and subfamilies indexed by function. Genome Res. 2003, 13, 2129-2141.
36. Dennis, G., Jr., Sherman, B. T., Hosack, D. A., Yang, J. et al., DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol. 2003, 4, 3.
37. Huang da, W., Sherman, B. T., Stephens, R., Baseler, M. W. et al., DAVID gene ID conversion tool. Bioinformation 2008, 2, 428-430.
38. Dai, J., Min, J., Xiao, Y., Lei, X. et al., The absence of mitochondrial DNA diversity among common laboratory inbred mouse strains. J. Exp. Biol. 2005, 208, 4445-4450.
39. Pucciarelli, S., Codello1, L., Rosato, A., Del Bianco, P. et al., Effect of antiadhesive agents on peritoneal carcinomatosis in an experimental model. Br. J. Surg. 2003, 90, 66-71.
40. Cox, B., Kislinger, T., Emili, A., Integrating gene and protein expression data: pattern analysis and profile mining. Methods 2005, 35, 303-314.
41. Tian, Q., Stepaniants, S. B., Mao, M., Wang, L. et al., Integrated genomic and proteomic analyses of gene expression in mammalian cells. Mol. Cell Proteomics 2004, 3, 960-969.
42. Cui, X., Song, B., Hou, L., Wei, Z. et al., High expression of osteoglycin decreases the metastatic capability of mouse hepatocarcinoma Hca-F cells to lymph nodes. Acta Biochim. Biophys. Sin. (Shanghai) 2008, 44, 349-355.
43. Dai, J. G., Lei, X., Min, J. X., Zhang, G. Q. et al., Mitochondrial DNA sequence analysis of two mouse hepatocarcinoma cell lines. World J. Gastroenterol. 2005, 11, 264-267.
44. Jia, L., Wang, S., Cao, J., Zhou, H. et al., siRNA targeted against matrix metalloproteinase 11 inhibits the metastatic capability of murine hepatocarcinoma cell Hca-F to lymph nodes. Int. J. Biochem. Cell Biol. 2007, 39, 2049-2062.
45. Fahling, M., Steege, A., Perlewitz, A., Nafz, B. et al., Role of nucleolin in posttranscriptional control of MMP-9 expression. Biochim. Biophys. Acta 2005, 1731, 32-40.
46. Tate, A., Isotani, S., Bradley, M. J., Sikes, R. A. et al., Metindependent hepatocyte growth factor-mediated regulation of cell adhesion in human prostate cancer cells. BMC Cancer 2006, 6, 197.
47. Tzao, C., Hsu, H. S., Sun, G. H., Lai, H. L. et al., Promoter methylation of the hMLH1 gene and protein expression of human mutL homolog 1 and human mutS homolog 2 in resected esophageal squamous cell carcinoma. J. Thorac. Cardiovasc. Surg. 2005, 130, 1371-1378.
48. Yamamoto, M., Taguchi, K., Baba, H., Endo, K. et al., Loss of protein expression of hMLH1 and hMSH2 with double primary carcinomas of the stomach and colorectum. Oncol. Rep. 2006, 16, 41-47.
49. Amiri, A., Noei, F., Jeganathan, S., Kulkarni, G. et al., eEF1A2 activates Akt and stimulates Akt-dependent actin remodeling, invasion and migration. Oncogene 2007, 26, 3027-3040.
50. Jeganathan, S., Lee, J. M., Binding of elongation factor eEF1A2 to phosphatidylinositol 4-kinase beta stimulates lipid kinase activity and phosphatidylinositol 4-phosphate generation. J. Biol. Chem. 2007, 282, 372-380.
51. Jin, W., Bruno, I. G., Xie, T. X., Sanger, L. J., Cote, G. J., Polypyrimidine tract-binding protein down-regulates fibroblast growth factor receptor 1 alpha-exon inclusion. Cancer Res. 2003, 63, 6154-6157.
52. Wagner, E. J., Carstens, R. P., Garcia-Blanco, M. A., A novel isoform ratio switch of the polypyrimidine tract binding protein. Electrophoresis 1999, 20, 1082-1086.
53. Eberle, J., Krasagakis, K., Orfanos, C. E., Translation initiation factor eIF-4A1 mRNA is consistently overexpressed in human melanoma cells in vitro. Int. J. Cancer 1997, 71, 397-401.
54. Scala, G., Ruocco, M. R., Ambrosino, C., Mallardo, M. et al., The expression of the interleukin 6 gene is induced by the human immunodeficiency virus 1 TAT protein. J. Exp. Med. 1994, 179, 961-971.
55. Massambu, C., Pyakurel, P., Kaaya, E., Enbom, M. et al., Cross-talk between human herpesvirus 8 and the transactivator protein in the pathogenesis of Kaposi's sarcoma in HIV-infected patients. Anticancer Res. 2003, 23, 2389-2395.
56. Saramaki, O., Willi, N., Bratt, O., Gasser, T. C. et al., Amplification of EIF3S3 gene is associated with advanced stage in prostate cancer. Am. J. Pathol. 2001, 159, 2089-2094.
57. Ahlemann, M., Zeidler, R., Lang, S., Mack, B. et al., Carcinoma-associated eIF3i overexpression facilitates mTOR-dependent growth transformation. Mol. Carcinog. 2006, 45, 957-967.
58. Byrjalsen, I., Mose Larsen, P., Fey, S. J., Nilas, L., Larsen, M. R., Christiansen, C., Two-dimensional gel analysis of human endometrial proteins: characterization of proteins with increased expression in hyperplasia and adenocarcinoma. Mol. Hum. Reprod. 1999, 5, 748-756.
59. Antoniou, M., Harland, L., Mustoe, T., Williams, S. et al., Transgenes encompassing dual-promoter CpG islands from the human TBP and HNRPA2B1 loci are resistant to heterochromatin-mediated silencing. Genomics 2003, 82, 269-279.
60. Fahling, M., Mrowka, R., Steege, A., Martinka, P. et al., Heterogeneous nuclear ribonucleoprotein-A2/B1 modulate collagen prolyl 4-hydroxylase, alpha (I) mRNA stability. J. Biol. Chem. 2006, 281, 9279-9286.
61. Mikheev, A. M., Inoue, A., Jing, L., Mikheeva, S. A. et al., Frequent activation of CArG binding factor-A expression and binding in N-methyl-N-nitrosourea- induced rat mammary carcinomas. Breast Cancer Res. Treat. 2004, 88, 95-102.
62. Eley, H. L., Russell, S. T., Tisdale, M. J., Effect of branched-chain amino acids on muscle atrophy in cancer cachexia. Biochem. J. 2007, 407, 113-120.
63. Sacchi, A., Chinali, G., Ferrini, U., Association of elongation factor 2 with ribosomes during growth of a murine ascitic tumor. Cancer Biochem. Biophys. 1983, 6, 179-187.
64. Radomski, N., Jost, E., Molecular cloning of a murine cDNA encoding a novel protein, p38-2G4, which varies with the cell cycle. Exp. Cell. Res. 1995, 220, 434-445.
65. Zhang, W. K., Shen, Y. G., He, X. J., Du, B. X. et al., Characterization of a novel cell cycle-related gene from Arabidopsis. J. Exp. Bot. 2005, 56, 807-816.
66. Kwon, J., Wang, Y. L., Setsuie, R., Sekiguchi, S. et al., Two closely related ubiquitin C-terminal hydrolase isozymes function as reciprocal modulators of germ cell apoptosis in cryptorchid testis. Am. J. Pathol. 2004, 165, 1367-1374.
67. Kwon, J., The new function of two ubiquitin C-terminal hydrolase isozymes as reciprocal modulators of germ cell apoptosis. Exp. Anim. 2007, 56, 71-77.
68. Sano, Y., Furuta, A., Setsuie, R., Kikuchi, H. et al., Photo-receptor cell apoptosis in the retinal degeneration of Uchl3-deficient mice. Am. J. Pathol. 2006, 169, 132-141.
69. Miyoshi, Y., Nakayama, S., Torikoshi, Y., Tanaka, S. et al., High expression of ubiquitin carboxy-terminal hydrolase-L1 and -L3 mRNA predicts early recurrence in patients with invasive breast cancer. Cancer Sci. 2006, 97, 523-529.
70. Myung, J., Afjehi-Sadat, L., Felizardo-Cabatic, M., Slavc, I., Lubec, G., Expressional patterns of chaperones in ten human tumor cell lines. Proteome Sci. 2004, 2, 8.
71. Hubbard, M. J., McHugh, N. J., Human ERp29: isolation, primary structural characterisation and two-dimensional gel mapping. Electrophoresis 2000, 21, 3785-3796.
72. Sargsyan, E., Baryshev, M., Szekely, L., Sharipo, A., Mkrtchian, S., Identification of ERp29, an endoplasmic reticulum lumenal protein, as a new member of the thyroglobulin folding complex. J. Biol. Chem. 2002, 277, 17009-17015.
73. Shnyder, S. D., Hubbard, M. J., ERp29 is a ubiquitous resident of the endoplasmic reticulum with a distinct role in secretory protein production. J. Histochem. Cytochem. 2002, 50, 557-566.
74. Srivastava, M., Montagna, C., Leighton, X., Glasman, M. et al., Haploinsufficiency of Anx7 tumor suppressor gene and consequent genomic instability promotes tumorigenesis in the Anx7(+/-) mouse. Proc. Natl. Acad. Sci. USA. 2003, 100, 14287-14292.
75. Srivastava, M., Bubendorf, L., Raffeld, M., Bucher, C. et al., Prognostic impact of ANX7-GTPase inmetastatic and HER2-negative breast cancer patients. Clin. Cancer Res. 2004, 10, 2344-2350.