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Volumn 9, Issue , 2009, Pages

Colorectal carcinomas in MUTYH-associated polyposis display histopathological similarities to microsatellite unstable carcinomas

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; BETA CATENIN; CD3 ANTIGEN; CD57 ANTIGEN; CD8 ANTIGEN; DNA GLYCOSYLASE MUTY; GRANZYME B; GUANINE; K RAS PROTEIN; PROTEIN P53; SMAD4 PROTEIN; THYMINE; DNA GLYCOSYLTRANSFERASE;

EID: 67650751794     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-9-184     Document Type: Article
Times cited : (49)

References (44)
  • 1
    • 7944225535 scopus 로고    scopus 로고
    • Association between biallelic and monoallelic germline MYH gene mutations and colorectal cancer risk
    • 15523092
    • Croitoru ME Cleary SP Di Nicola N Manno M Selander T Aronson M et al. Association between biallelic and monoallelic germline MYH gene mutations and colorectal cancer risk J Natl Cancer Inst 2004, 96:1631-1634. 15523092
    • (2004) J Natl Cancer Inst , vol.96 , pp. 1631-1634
    • Croitoru, M.E.1    Cleary, S.P.2    Di Nicola, N.3    Manno, M.4    Selander, T.5    Aronson, M.6
  • 2
    • 3242689475 scopus 로고    scopus 로고
    • MYH mutations in patients with attenuated and classic polyposis and with young-onset colorectal cancer without polyps
    • 10.1053/j.gastro.2004.03.070 15236166
    • Wang L Baudhuin LM Boardman LA Steenblock KJ Petersen GM Halling KC MYH mutations in patients with attenuated and classic polyposis and with young-onset colorectal cancer without polyps Gastroenterology 2004, 127:9-16. 10.1053/j.gastro.2004.03.070 15236166
    • (2004) Gastroenterology , vol.127 , pp. 9-16
    • Wang, L.1    Baudhuin, L.M.2    Boardman, L.A.3    Steenblock, K.J.4    Petersen, G.M.5    Halling, K.C.6
  • 3
    • 33746775351 scopus 로고    scopus 로고
    • Multiplicity in polyp count and extracolonic manifestations in 40 Dutch patients with MYH associated polyposis coli (MAP)
    • 1736132 16140997 10.1136/jmg.2005.033217
    • Nielsen M Franken PF Reinards TH Weiss MM Wagner A van der KH et al. Multiplicity in polyp count and extracolonic manifestations in 40 Dutch patients with MYH associated polyposis coli (MAP) J Med Genet 2005, 42:e54. 1736132 16140997 10.1136/jmg.2005.033217
    • (2005) J Med Genet , vol.42
    • Nielsen, M.1    Franken, P.F.2    Reinards, T.H.3    Weiss, M.M.4    Wagner, A.5    van der, K.H.6
  • 4
    • 33745903402 scopus 로고    scopus 로고
    • MUTYH-associated polyposis: 70 of 71 patients with biallelic mutations present with an attenuated or atypical phenotype
    • 10.1002/ijc.21905 16557584
    • Aretz S Uhlhaas S Goergens H Siberg K Vogel M Pagenstecher C et al. MUTYH-associated polyposis: 70 of 71 patients with biallelic mutations present with an attenuated or atypical phenotype Int J Cancer 2006, 119:807-814. 10.1002/ijc.21905 16557584
    • (2006) Int J Cancer , vol.119 , pp. 807-814
    • Aretz, S.1    Uhlhaas, S.2    Goergens, H.3    Siberg, K.4    Vogel, M.5    Pagenstecher, C.6
  • 5
    • 40749120502 scopus 로고    scopus 로고
    • Identification of Patients with (Atypical) MUTYH-Associated Polyposis by KRAS2 c.34G > T Prescreening Followed by MUTYH Hotspot Analysis in Formalin-Fixed Paraffin-Embedded Tissue
    • 10.1158/1078-0432.CCR-07-1705 18172263
    • Van Puijenbroek M Nielsen M Tops CM Halfwerk H Vasen HF Weiss MM et al. Identification of Patients with (Atypical) MUTYH-Associated Polyposis by KRAS2 c.34G > T Prescreening Followed by MUTYH Hotspot Analysis in Formalin-Fixed Paraffin-Embedded Tissue Clin Cancer Res 2008, 14:139-142. 10.1158/1078-0432.CCR-07-1705 18172263
    • (2008) Clin Cancer Res , vol.14 , pp. 139-142
    • Van Puijenbroek, M.1    Nielsen, M.2    Tops, C.M.3    Halfwerk, H.4    Vasen, H.F.5    Weiss, M.M.6
  • 6
    • 33947280508 scopus 로고    scopus 로고
    • Identification of MYH mutation carriers in colorectal cancer: A multicenter, case-control, population-based study
    • 10.1016/j.cgh.2006.12.025 17368238
    • Balaguer F Castellvi-Bel S Castells A Andreu M Munoz J Gisbert JP et al. Identification of MYH mutation carriers in colorectal cancer: A multicenter, case-control, population-based study Clin Gastroenterol Hepatol 2007, 5:379-387. 10.1016/j.cgh.2006.12.025 17368238
    • (2007) Clin Gastroenterol Hepatol , vol.5 , pp. 379-387
    • Balaguer, F.1    Castellvi-Bel, S.2    Castells, A.3    Andreu, M.4    Munoz, J.5    Gisbert, J.P.6
  • 7
    • 20544452084 scopus 로고    scopus 로고
    • Germline susceptibility to colorectal cancer due to base-excision repair gene defects
    • 1226182 15931596 10.1086/431213
    • Farrington SM Tenesa A Barnetson R Wiltshire A Prendergast J Porteous M et al. Germline susceptibility to colorectal cancer due to base-excision repair gene defects Am J Hum Genet 2005, 77:112-119. 1226182 15931596 10.1086/431213
    • (2005) Am J Hum Genet , vol.77 , pp. 112-119
    • Farrington, S.M.1    Tenesa, A.2    Barnetson, R.3    Wiltshire, A.4    Prendergast, J.5    Porteous, M.6
  • 8
    • 44149127195 scopus 로고    scopus 로고
    • Contribution of common monoallelic MUTYH gene variants in German patients with familial colorectal cancer
    • 18503156
    • Grunhage F Jungck M Lamberti C Schulte-Witte H Plassmann D Becker U et al. Contribution of common monoallelic MUTYH gene variants in German patients with familial colorectal cancer Cancer Biomark 2008, 4:55-61. 18503156
    • (2008) Cancer Biomark , vol.4 , pp. 55-61
    • Grunhage, F.1    Jungck, M.2    Lamberti, C.3    Schulte-Witte, H.4    Plassmann, D.5    Becker, U.6
  • 9
    • 48749090886 scopus 로고    scopus 로고
    • The role of MYH gene in genetic predisposition to colorectal cancer: Another piece of the puzzle
    • 10.1016/j.canlet.2008.04.004 18495334
    • Avezzu A Agostini M Pucciarelli S Lise M Urso ED Mammi I et al. The role of MYH gene in genetic predisposition to colorectal cancer: Another piece of the puzzle Cancer Lett 2008, 268:308-313. 10.1016/ j.canlet.2008.04.004 18495334
    • (2008) Cancer Lett , vol.268 , pp. 308-313
    • Avezzu, A.1    Agostini, M.2    Pucciarelli, S.3    Lise, M.4    Urso, E.D.5    Mammi, I.6
  • 10
    • 0036478899 scopus 로고    scopus 로고
    • Inherited variants of MYH associated with somatic G:C→T:A mutations in colorectal tumours
    • 10.1038/ng828 11818965
    • Al Tassan N Chmiel NH Maynard J Fleming N Livingston AL Williams GT Inherited variants of MYH associated with somatic G:C→T:A mutations in colorectal tumours Nat Genet 2002, 30:227-232. 10.1038/ng828 11818965
    • (2002) Nat Genet , vol.30 , pp. 227-232
    • Al Tassan, N.1    Chmiel, N.H.2    Maynard, J.3    Fleming, N.4    Livingston, A.L.5    Williams, G.T.6
  • 11
    • 10744220394 scopus 로고    scopus 로고
    • Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway
    • 14633673
    • Lipton L Halford SE Johnson V Novelli MR Jones A Cummings C et al. Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway Cancer Res 2003, 63:7595-7599. 14633673
    • (2003) Cancer Res , vol.63 , pp. 7595-7599
    • Lipton, L.1    Halford, S.E.2    Johnson, V.3    Novelli, M.R.4    Jones, A.5    Cummings, C.6
  • 12
    • 0035444798 scopus 로고    scopus 로고
    • Kirsten ras mutations in patients with colorectal cancer: The 'RASCAL II' study
    • 10.1054/bjoc.2001.1964 11531254
    • Andreyev HJ Norman AR Cunningham D Oates J Dix BR Iacopetta BJ et al. Kirsten ras mutations in patients with colorectal cancer: The 'RASCAL II' study Br J Cancer 2001, 85:692-696. 10.1054/bjoc.2001.1964 11531254
    • (2001) Br J Cancer , vol.85 , pp. 692-696
    • Andreyev, H.J.1    Norman, A.R.2    Cunningham, D.3    Oates, J.4    Dix, B.R.5    Iacopetta, B.J.6
  • 13
    • 50249133223 scopus 로고    scopus 로고
    • High frequency of copy-neutral LOH in MUTYH-associated polyposis carcinomas
    • 10.1002/path.2375 18506705
    • Middeldorp A Van Puijenbroek M Nielsen M Corver W Jordanova E Ter Haar N et al. High frequency of copy-neutral LOH in MUTYH-associated polyposis carcinomas J Pathol 2008, 216:25-31. 10.1002/path.2375 18506705
    • (2008) J Pathol , vol.216 , pp. 25-31
    • Middeldorp, A.1    Van Puijenbroek, M.2    Nielsen, M.3    Corver, W.4    Jordanova, E.5    Ter Haar, N.6
  • 14
    • 0033021439 scopus 로고    scopus 로고
    • High prevalence of activated intraepithelial cytotoxic T lymphocytes and increased neoplastic cell apoptosis in colorectal carcinomas with microsatellite instability
    • 1866613 10362805
    • Dolcetti R Viel A Doglioni C Russo A Guidoboni M Capozzi E et al. High prevalence of activated intraepithelial cytotoxic T lymphocytes and increased neoplastic cell apoptosis in colorectal carcinomas with microsatellite instability Am J Pathol 1999, 154:1805-1813. 1866613 10362805
    • (1999) Am J Pathol , vol.154 , pp. 1805-1813
    • Dolcetti, R.1    Viel, A.2    Doglioni, C.3    Russo, A.4    Guidoboni, M.5    Capozzi, E.6
  • 15
    • 0035132202 scopus 로고    scopus 로고
    • Histopathological identification of colon cancer with microsatellite instability
    • 1850324 11159189
    • Alexander J Watanabe T Wu TT Rashid A Li S Hamilton SR Histopathological identification of colon cancer with microsatellite instability Am J Pathol 2001, 158:527-535. 1850324 11159189
    • (2001) Am J Pathol , vol.158 , pp. 527-535
    • Alexander, J.1    Watanabe, T.2    Wu, T.T.3    Rashid, A.4    Li, S.5    Hamilton, S.R.6
  • 16
    • 0038002279 scopus 로고    scopus 로고
    • Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer
    • 10.1056/NEJMoa022289 12867608
    • Ribic CM Sargent DJ Moore MJ Thibodeau SN French AJ Goldberg RM et al. Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer N Engl J Med 2003, 349:247-257. 10.1056/NEJMoa022289 12867608
    • (2003) N Engl J Med , vol.349 , pp. 247-257
    • Ribic, C.M.1    Sargent, D.J.2    Moore, M.J.3    Thibodeau, S.N.4    French, A.J.5    Goldberg, R.M.6
  • 17
    • 33749319703 scopus 로고    scopus 로고
    • Type, density, and location of immune cells within human colorectal tumours predict clinical outcome
    • 10.1126/science.1129139 17008531
    • Galon J Costes A Sanchez-Cabo F Kirilovsky A Mlecnik B Lagorce-Pages C et al. Type, density, and location of immune cells within human colorectal tumours predict clinical outcome Science 2006, 313:1960-1964. 10.1126/science.1129139 17008531
    • (2006) Science , vol.313 , pp. 1960-1964
    • Galon, J.1    Costes, A.2    Sanchez-Cabo, F.3    Kirilovsky, A.4    Mlecnik, B.5    Lagorce-Pages, C.6
  • 19
    • 84924637969 scopus 로고
    • Multiple carcinomas of the large intestine: A review of the literature and a study of 261 cases
    • 13501357
    • Moertel CG Bargen JA Dockerty MB Multiple carcinomas of the large intestine: A review of the literature and a study of 261 cases Gastroenterology 1958, 34:85-98. 13501357
    • (1958) Gastroenterology , vol.34 , pp. 85-98
    • Moertel, C.G.1    Bargen, J.A.2    Dockerty, M.B.3
  • 20
    • 0025424347 scopus 로고
    • Crohn's-like lymphoid reaction and colorectal carcinoma: A potential histologic prognosticator
    • 2362940
    • Graham DM Appelman HD Crohn's-like lymphoid reaction and colorectal carcinoma: A potential histologic prognosticator Mod Pathol 1990, 3:332-335. 2362940
    • (1990) Mod Pathol , vol.3 , pp. 332-335
    • Graham, D.M.1    Appelman, H.D.2
  • 21
    • 10744232899 scopus 로고    scopus 로고
    • Microsatellite instability, immunohistochemistry, and additional PMS2 staining in suspected hereditary nonpolyposis colorectal cancer
    • 10.1158/1078-0432.CCR-0956-3 14871975
    • de Jong AE Van Puijenbroek M Hendriks Y Tops C Wijnen J Ausems MG et al. Microsatellite instability, immunohistochemistry, and additional PMS2 staining in suspected hereditary nonpolyposis colorectal cancer Clin Cancer Res 2004, 10:972-980. 10.1158/1078-0432.CCR-0956-3 14871975
    • (2004) Clin Cancer Res , vol.10 , pp. 972-980
    • de Jong, A.E.1    Van Puijenbroek, M.2    Hendriks, Y.3    Tops, C.4    Wijnen, J.5    Ausems, M.G.6
  • 22
    • 0032534069 scopus 로고    scopus 로고
    • A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
    • 9823339
    • Boland CR Thibodeau SN Hamilton SR Sidransky D Eshleman JR Burt RW A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer Cancer Res 1998, 58:5248-5257. 9823339
    • (1998) Cancer Res , vol.58 , pp. 5248-5257
    • Boland, C.R.1    Thibodeau, S.N.2    Hamilton, S.R.3    Sidransky, D.4    Eshleman, J.R.5    Burt, R.W.6
  • 24
    • 67650750036 scopus 로고    scopus 로고
    • Ref Type: Internet Communication
    • LUMC, DNA-diagnostics 2009 http://www.lumc.nl/4080/DNA/MUTYH.html Ref Type: Internet Communication
    • (2009) LUMC, DNA-diagnostics
  • 25
    • 67650750037 scopus 로고    scopus 로고
    • Ref Type: Internet Communication
    • Leiden Open Variation Database 2009 http://chromium.liacs.nl/LOVD2/ home.php?select_db=MUTYH Ref Type: Internet Communication
    • (2009) Leiden Open Variation Database
  • 26
    • 22844452823 scopus 로고    scopus 로고
    • LOVD: Easy creation of a locus-specific sequence variation database using an "LSDB-in-a-box" approach
    • 10.1002/humu.20201 15977173
    • Fokkema IF den Dunnen JT Taschner PE LOVD: Easy creation of a locus-specific sequence variation database using an "LSDB-in-a-box" approach Hum Mutat 2005, 26:63-68. 10.1002/ humu.20201 15977173
    • (2005) Hum Mutat , vol.26 , pp. 63-68
    • Fokkema, I.F.1    den Dunnen, J.T.2    Taschner, P.E.3
  • 27
    • 0037332143 scopus 로고    scopus 로고
    • Conventional and tissue microarray immunohistochemical expression analysis of mismatch repair in hereditary colorectal tumours
    • 1851154 12547705
    • Hendriks Y Franken P Dierssen JW De Leeuw W Wijnen J Dreef E et al. Conventional and tissue microarray immunohistochemical expression analysis of mismatch repair in hereditary colorectal tumours Am J Pathol 2003, 162:469-477. 1851154 12547705
    • (2003) Am J Pathol , vol.162 , pp. 469-477
    • Hendriks, Y.1    Franken, P.2    Dierssen, J.W.3    De Leeuw, W.4    Wijnen, J.5    Dreef, E.6
  • 28
    • 22544445830 scopus 로고    scopus 로고
    • Four-color staining combining fluorescence and brightfield microscopy for simultaneous immune cell phenotyping and localization in tumor tissue sections
    • 10.1002/jemt.20181 16025486
    • van Vlierberghe RL Sandel MH Prins FA van Iersel LB Velde Van De CJ Tollenaar RA et al. Four-color staining combining fluorescence and brightfield microscopy for simultaneous immune cell phenotyping and localization in tumor tissue sections Microsc Res Tech 2005, 67:15-21. 10.1002/jemt.20181 16025486
    • (2005) Microsc Res Tech , vol.67 , pp. 15-21
    • van Vlierberghe, R.L.1    Sandel, M.H.2    Prins, F.A.3    van Iersel, L.B.4    Velde, C.J.5    Tollenaar, R.A.6
  • 29
    • 67650738031 scopus 로고    scopus 로고
    • Ref Type: Internet Communication
    • The p53 WebB Site 2009 http://p53.free.fr/index.html Ref Type: Internet Communication
    • (2009) The P53 WebB Site
  • 30
    • 0030061148 scopus 로고    scopus 로고
    • Better survival rates in patients with MLH1-associated hereditary colorectal cancer
    • 10.1053/gast.1996.v110.pm8608876 8608876
    • Sankila R Aaltonen LA Jarvinen HJ Mecklin JP Better survival rates in patients with MLH1-associated hereditary colorectal cancer Gastroenterology 1996, 110:682-687. 10.1053/gast.1996.v110.pm8608876 8608876
    • (1996) Gastroenterology , vol.110 , pp. 682-687
    • Sankila, R.1    Aaltonen, L.A.2    Jarvinen, H.J.3    Mecklin, J.P.4
  • 31
    • 47749140060 scopus 로고    scopus 로고
    • Pathological features of colorectal carcinomas in MYH-associated polyposis
    • 10.1111/j.1365-2559.2008.03071.x 18564191
    • O'Shea AM Cleary SP Croitoru MA Kim H Berk T Monga N et al. Pathological features of colorectal carcinomas in MYH-associated polyposis Histopathology 2008, 53:184-194. 10.1111/j.1365-2559.2008.03071.x 18564191
    • (2008) Histopathology , vol.53 , pp. 184-194
    • O'Shea, A.M.1    Cleary, S.P.2    Croitoru, M.A.3    Kim, H.4    Berk, T.5    Monga, N.6
  • 32
    • 0000151696 scopus 로고    scopus 로고
    • Hereditary nonpolyposis colorectal cancer: An approach to the selection of candidates to genetic testing based on clinical and molecular characteristics
    • 10.1159/000016168 15178966
    • Viel A Genuardi M Lucci-Cordisco E Capozzi E Rovella V Fornasarig M et al. Hereditary nonpolyposis colorectal cancer: An approach to the selection of candidates to genetic testing based on clinical and molecular characteristics Community Genet 1998, 1:229-236. 10.1159/ 000016168 15178966
    • (1998) Community Genet , vol.1 , pp. 229-236
    • Viel, A.1    Genuardi, M.2    Lucci-Cordisco, E.3    Capozzi, E.4    Rovella, V.5    Fornasarig, M.6
  • 33
    • 5544242524 scopus 로고    scopus 로고
    • Microsatellite instability and high content of activated cytotoxic lymphocytes identify colon cancer patients with a favorable prognosis
    • 1850401 11438476
    • Guidoboni M Gafa R Viel A Doglioni C Russo A Santini A et al. Microsatellite instability and high content of activated cytotoxic lymphocytes identify colon cancer patients with a favorable prognosis Am J Pathol 2001, 159:297-304. 1850401 11438476
    • (2001) Am J Pathol , vol.159 , pp. 297-304
    • Guidoboni, M.1    Gafa, R.2    Viel, A.3    Doglioni, C.4    Russo, A.5    Santini, A.6
  • 34
    • 2342514891 scopus 로고    scopus 로고
    • Immune system and prognosis in colorectal cancer: A detailed immunohistochemical analysis
    • 10.1038/labinvest.3700055 14968119
    • Menon AG Janssen-van Rhijn CM Morreau H Putter H Tollenaar RA Velde Van De CJ et al. Immune system and prognosis in colorectal cancer: A detailed immunohistochemical analysis Lab Invest 2004, 84:493-501. 10.1038/labinvest.3700055 14968119
    • (2004) Lab Invest , vol.84 , pp. 493-501
    • Menon, A.G.1    Janssen-van Rhijn, C.M.2    Morreau, H.3    Putter, H.4    Tollenaar, R.A.5    Velde, C.J.6
  • 35
    • 33947259556 scopus 로고    scopus 로고
    • APC mutations and other genetic and epigenetic changes in colon cancer
    • 10.1158/1541-7786.MCR-06-0398 17293392
    • Samowitz WS Slattery ML Sweeney C Herrick J Wolff RK Albertsen H APC mutations and other genetic and epigenetic changes in colon cancer Mol Cancer Res 2007, 5:165-170. 10.1158/1541-7786.MCR-06-0398 17293392
    • (2007) Mol Cancer Res , vol.5 , pp. 165-170
    • Samowitz, W.S.1    Slattery, M.L.2    Sweeney, C.3    Herrick, J.4    Wolff, R.K.5    Albertsen, H.6
  • 36
    • 0028291928 scopus 로고
    • Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumours
    • 8187091
    • Miyaki M Konishi M Kikuchi-Yanoshita R Enomoto M Igari T Tanaka K et al. Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumours Cancer Res 1994, 54:3011-3020. 8187091
    • (1994) Cancer Res , vol.54 , pp. 3011-3020
    • Miyaki, M.1    Konishi, M.2    Kikuchi-Yanoshita, R.3    Enomoto, M.4    Igari, T.5    Tanaka, K.6
  • 37
    • 0026894053 scopus 로고
    • Somatic mutations of the APC gene in colorectal tumours: Mutation cluster region in the APC gene
    • 10.1093/hmg/1.4.229 1338904
    • Miyoshi Y Nagase H Ando H Horii A Ichii S Nakatsuru S et al. Somatic mutations of the APC gene in colorectal tumours: Mutation cluster region in the APC gene Hum Mol Genet 1992, 1:229-233. 10.1093/hmg/1.4.229 1338904
    • (1992) Hum Mol Genet , vol.1 , pp. 229-233
    • Miyoshi, Y.1    Nagase, H.2    Ando, H.3    Horii, A.4    Ichii, S.5    Nakatsuru, S.6
  • 38
    • 3242796729 scopus 로고    scopus 로고
    • APC mutations in sporadic colorectal carcinomas from The Netherlands Cohort Study
    • 10.1093/carcin/bgh117 14976131
    • Luchtenborg M Weijenberg MP Roemen GM de Bruine AP Brandt van den PA Lentjes MH et al. APC mutations in sporadic colorectal carcinomas from The Netherlands Cohort Study Carcinogenesis 2004, 25:1219-1226. 10.1093/ carcin/bgh117 14976131
    • (2004) Carcinogenesis , vol.25 , pp. 1219-1226
    • Luchtenborg, M.1    Weijenberg, M.P.2    Roemen, G.M.3    de Bruine, A.P.4    Brandt, P.A.5    Lentjes, M.H.6
  • 39
    • 38949128410 scopus 로고    scopus 로고
    • Progression and tumor heterogeneity analysis in early rectal cancer
    • 10.1158/1078-0432.CCR-07-2052 18245538
    • Lips EH Van ER de Graaf EJ Doornebosch PG de Miranda NF Oosting J et al. Progression and tumor heterogeneity analysis in early rectal cancer Clin Cancer Res 2008, 14:772-781. 10.1158/1078-0432.CCR-07-2052 18245538
    • (2008) Clin Cancer Res , vol.14 , pp. 772-781
    • Lips, E.H.1    Van, E.R.2    de Graaf, E.J.3    Doornebosch, P.G.4    de Miranda, N.F.5    Oosting, J.6
  • 40
    • 2442536038 scopus 로고    scopus 로고
    • Increased frequency of the k-ras G12C mutation in MYH polyposis colorectal adenomas
    • 10.1038/sj.bjc.6601747 15083190
    • Jones S Lambert S Williams GT Best JM Sampson JR Cheadle JP Increased frequency of the k-ras G12C mutation in MYH polyposis colorectal adenomas Br J Cancer 2004, 90:1591-1593. 10.1038/sj.bjc.6601747 15083190
    • (2004) Br J Cancer , vol.90 , pp. 1591-1593
    • Jones, S.1    Lambert, S.2    Williams, G.T.3    Best, J.M.4    Sampson, J.R.5    Cheadle, J.P.6
  • 41
    • 5444224121 scopus 로고    scopus 로고
    • Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status
    • 10.1093/hmg/ddh238 15294875
    • Oliveira C Westra JL Arango D Ollikainen M Domingo E Ferreira A et al. Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status Hum Mol Genet 2004, 13:2303-2311. 10.1093/hmg/ddh238 15294875
    • (2004) Hum Mol Genet , vol.13 , pp. 2303-2311
    • Oliveira, C.1    Westra, J.L.2    Arango, D.3    Ollikainen, M.4    Domingo, E.5    Ferreira, A.6
  • 42
    • 28844506365 scopus 로고    scopus 로고
    • Mutant KRAS in aberrant crypt foci (ACF): Initiation of colorectal cancer?
    • 16219426
    • Pretlow TP Pretlow TG Mutant KRAS in aberrant crypt foci (ACF): initiation of colorectal cancer? Biochim Biophys Acta 2005, 1756:83-96. 16219426
    • (2005) Biochim Biophys Acta , vol.1756 , pp. 83-96
    • Pretlow, T.P.1    Pretlow, T.G.2
  • 43
    • 33750433538 scopus 로고    scopus 로고
    • The role of MYH and microsatellite instability in the development of sporadic colorectal cancer
    • 10.1038/sj.bjc.6603421 17031395
    • Colebatch A Hitchins M Williams R Meagher A Hawkins NJ Ward RL The role of MYH and microsatellite instability in the development of sporadic colorectal cancer Br J Cancer 2006, 95:1239-1243. 10.1038/sj.bjc.6603421 17031395
    • (2006) Br J Cancer , vol.95 , pp. 1239-1243
    • Colebatch, A.1    Hitchins, M.2    Williams, R.3    Meagher, A.4    Hawkins, N.J.5    Ward, R.L.6
  • 44
    • 33751311531 scopus 로고    scopus 로고
    • Implication of MYH in colorectal polyposis
    • 1856630 17122612 10.1097/01.sla.0000246937.54435.50
    • Lefevre JH Rodrigue CM Mourra N Bennis M Flejou JF Parc R et al. Implication of MYH in colorectal polyposis Ann Surg 2006, 244:874-879. 1856630 17122612 10.1097/01.sla.0000246937.54435.50
    • (2006) Ann Surg , vol.244 , pp. 874-879
    • Lefevre, J.H.1    Rodrigue, C.M.2    Mourra, N.3    Bennis, M.4    Flejou, J.F.5    Parc, R.6


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