Mechanism of drug and toxic actions of Gossypol: Focus on reactive oxygen species and electron transfer

Current Medicinal Chemistry

Volumn 10, Issue 24, 2003, Pages 2711-2718

  Kovaci, Peter ^a  

^a SAN DIEGO STATE UNIVERSITY   (United States)

Author keywords

Drug; Electrochemistry; Electron transfer; Gossypol; Mechanism; Metabolites; Oxidative stress; Reactive oxygen species; Toxin

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; ACRIDINE; ALPHA TOCOPHEROL; ANTHRACYCLINE DERIVATIVE; ANTIPARASITIC AGENT; ANTIVIRUS AGENT; ASCORBIC ACID; BLEOMYCIN IRON; CARDIOTOXIN; CISPLATIN; DRUG METABOLITE; ELLIPTICINE DERIVATIVE; ETOPOSIDE; GOSSYPOL; HYDRAZONE DERIVATIVE; MITOMYCIN C; NITROBENZENE DERIVATIVE; PHANQUINONE; PHENOL DERIVATIVE; QUINOLINE DERIVATIVE; REACTIVE OXYGEN METABOLITE; SALICYLALDOXIME; SCHIFF BASE; TIRAPAZAMINE;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIPROTOZOAL ACTIVITY; ANTIVIRAL ACTIVITY; CARDIOTOXICITY; CELL COMMUNICATION; DRUG MECHANISM; DRUG STRUCTURE; ELECTRON TRANSPORT; ENZYME INHIBITION; GENITAL SYSTEM; HUMAN; IN VIVO STUDY; LIVER TOXICITY; MALE INFERTILITY; MEMBRANE DAMAGE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; REPRODUCTIVE TOXICITY; REVIEW; SPERMATOZOON; UTERUS MYOMA;

ANIMALS; ELECTRON TRANSPORT; GOSSYPOL; HUMANS; REACTIVE OXYGEN SPECIES;

EID: 0344824649     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867033456369     Document Type: Review

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