Stress-induced dilated cardiomyopathy in a knock-in mouse model mimicking human titin-based disease

Journal of Molecular and Cellular Cardiology

Volumn 47, Issue 3, 2009, Pages 352-358

  Gramlich, Michael ^a,b   Michely, Beate ^c   Krohne, Christian ^d   Heuser, Arnd ^a   Erdmann, Bettina ^a   Klaassen, Sabine ^a   Hudson, Bryan ^e   Magarin, Manuela ^a   Kirchner, Florian ^a   Todiras, Mihail ^a   Granzier, Henk ^e   Labeit, Siegfried ^d   Thierfelder, Ludwig ^a,c   Gerull, Brenda ^a,c  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b VICTOR CHANG CARDIAC RESEARCH INSTITUTE   (Australia)

^c Helios Hospital Berlin Buch   (Germany)

^d UNIVERSITY OF HEIDELBERG   (Germany)

^e University of Arizona   (United States)

Author keywords

Cardiomyopathy; Development; Genetics; Heart failure; Mouse model; Pathogenesis; Sarcomere formation; Titin

Indexed keywords

ANGIOTENSIN II; CONNECTIN; ISOPRENALINE; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; DISEASE MODEL; EMBRYO; GENE EXPRESSION; GENE MUTATION; HEART MUSCLE FIBROSIS; HEART STRESS; HETEROZYGOSITY; HISTOPATHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ALLELES; ANIMALS; CARDIOMYOPATHY, DILATED; CROSSES, GENETIC; DISEASE MODELS, ANIMAL; DNA MUTATIONAL ANALYSIS; HEART FAILURE; HETEROZYGOTE; MICE; MODELS, GENETIC; MUSCLE PROTEINS; MUTATION; PHENOTYPE; PROTEIN KINASES; RNA, MESSENGER; TIME FACTORS;

MUS;

EID: 67650738888     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2009.04.014     Document Type: Article

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