Cloning and functional analysis of a family of nuclear matrix transcription factors (NP/NMP4) that regulate type I collagen expression in osteoblasts

Journal of Bone and Mineral Research

Volumn 16, Issue 1, 2001, Pages 10-23

  Thunyakitpisal, Pasutha ^b   Alvarez, Marta ^a   Tokunaga, Kunihiko ^c   Onyia, Jude E ^a,d   Hock, Janet ^a,c   Ohashi, Naoko ^c   Feister, Hilary ^c,e   Rhodes, Simon J ^f   Bidwell, Joseph P ^a,c  

^a INDIANA UNIVERSITY SCHOOL OF DENTISTRY   (United States)

^b CHULALONGKORN UNIVERSITY   (Thailand)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d ELI LILLY AND COMPANY   (United States)

^e PFIZER INC   (United States)

^f INDIANA UNIVERSITY   (United States)

Author keywords

Architectural transcription factors; Bone; Collagen; NP NMP4 CIZ; Nuclear matrix; Osteoblasts

Indexed keywords

COLLAGEN TYPE 1; COMPLEMENTARY DNA; METALLOPROTEIN; METALLOPROTEINASE; POLYPEPTIDE; TRANSCRIPTION FACTOR; ZINC FINGER PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CARTILAGE CELL; CLONING; DNA SEQUENCE; FIBROBLAST; GENE EXPRESSION; GENE ISOLATION; GENE MUTATION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; NONHUMAN; OSTEOBLAST; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; REPORTER GENE;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, NUCLEAR; BONE AND BONES; BONE DEVELOPMENT; CELL LINE; CLONING, MOLECULAR; COLLAGEN; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GENES, REPORTER; IN SITU HYBRIDIZATION; MALE; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEAR MATRIX; NUCLEAR MATRIX-ASSOCIATED PROTEINS; NUCLEAR PROTEINS; OSTEOBLASTS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN ISOFORMS; RATS; RATS, SPRAGUE-DAWLEY; RESPONSE ELEMENTS; RNA, MESSENGER; SEQUENCE ALIGNMENT; TRANSCRIPTION FACTORS; ZINC FINGERS;

EID: 0035163478     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2001.16.1.10     Document Type: Article

References (53)

1. Nuclear matrix proteins and osteoblast gene expression
2. Coupling of cell structure to cell metabolism and function
3. Extracellular matrix signaling from the cellular membrane skeleton to the nuclear skeleton: A model of gene regulation
4. The new paradigm: Integrating genomic function and nuclear architecture
5. Matrin CYP, an SR-rich cyclophilin that associates with the nuclear matrix and splicing factors
6. A PTH-responsive, osteoblast, nuclear matrix, architectural transcription factor, binds to the rat type I collagen promoter
7. Identification of YY1 sequences necessary for association with the nuclear matrix and for transcriptional repression functions
8. A c-erbB-2 promoter-specific nuclear matrix protein from human breast tumor tissues mediates NF-kappaB DNA binding activity
9. Nature of DNA sequences at the attachment regions of genes to the nuclear matrix
10. Protein motifs that recognize structural features of DNA
11. Assembly and function of a TCRα enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions
12. Multivalent DNA binding complex generated by small Maf and Bachl as a possible biochemical basis for beta-globin locus control region complex
13. Virus induction of human IFNβ gene expression requires the assembly of an enhanceosome
14. Architectural transcription factors
15. Upstream regulatory elements necessary for expression of the rat COL1A1 promoter in transgenic mice
16. Modulation and reexpression of the chondrocyte phenotype; mediation by cell shape and microfilament modification
17. Cell adhesion regulates pro-α1(I) collagen mRNA stability and transcription in mouse fibroblasts
18. Inhibition of collagen secretion from bone and cultured fibroblasts by microtubule disruptive drugs
19. Surface adhesion-mediated regulation of chondrocyte-specific gene expression in the nontransformed RCJ 3.1C5.18 rat chondrocyte cell line
20. CIZ, a zinc finger protein that interacts with pp. 130(cas) and activates the expression of matrix metalloproteinases
21. Molecular cloning of an enhancer binding protein: Isolation by screening of an expression library with a recognition site DNA
22. Parathyroid hormone regulates the expression of rat osteoblast and osteosarcoma nuclear matrix proteins
23. Characterization of the porcine Lhx3/LIM-3/P-Lim LIM homeodomain transcription factor
24. In vivo, human parathyroid hormone fragment (hPTH 1-34) transiently stimulates immediate early response gene expression, but not proliferation, in trabecular bone cells of young rats
25. Human osteosarcoma (OST) induces mouse reactive bone formation in xenograft system
26. The expression of the nuclear matrix proteins NuMA, topoisomerase II-α, and -β in bone and osseous cell culture: Regulation by parathyroid hormone
27. A pitfall of using a second plasmid to determine transfection efficiency
28. Parathyroid hormone regulates the rat collagenase-3 promoter in osteoblastic cells through the cooperative interaction of the activator protein-1 site and the runt domain binding sequence
29. Rat osteoblast and osteosarcoma nuclear matrix proteins bind with sequence specificity to the rat type I collagen promoter
30. DNA sequence preferences of several AT-selective minor groove binding ligands
31. AT-hook motifs identified in a wide variety of DNA-binding proteins
32. The AT-DNA-binding domain of mammalian high mobility group I chromosomal proteins
33. Modulation of nuclear matrix protein phosphorylation by histones: Possible involvement of NM-associated protein kinase CK2 activity
34. cDNAs with long CAG trinucleotide repeats from human brain
35. The NP/NMP4 transcription factors have distinct osteoblast nuclear matrix subdomains
36. A striking similarity in the organization of the E-selectin and beta interferon gene promoters
37. HMGI(Y) and Sp1 in addition to NF-kappa B regulate transcription of the MGSA/GRO alpha gene
38. Cloning and characterization of hcKrox, a transcriptional regulator of extracellular matrix gene expression
39. MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover
40. Coordinate increase in the expression of type I and type III collagen genes in progressive systemic sclerosis fibroblasts
41. Increased collagen synthesis by scleroderma skin fibroblasts in vitro: A possible defect in the regulation or activation of the scleroderma fibroblast
42. Interpreting cDNA sequences: Some insights from studies on translation
43. Identification of downstream-initiated c-Myc proteins which are dominant-negative inhibitors of transactivation by full-length c-Myc proteins
44. The KRAB zinc finger gene ZNF74 encodes an RNA-binding protein tightly associated with the nuclear matrix
45. Multiple mechanisms of transcriptional repression by YY1
46. Structural and functional analyses of DNA bending induced by Sp1 family transcription factors
47. The solution structure of an HMG-I(Y)-DNA complex defines a new architectural minor groove binding motif
48. Platelet-derived growth factor-stimulated expression of the MCP-1 immediate-early gene involves an inhibitory multiprotein complex
49. DNA looping and Sp1 multimer links: A mechanism for transcriptional synergism and enhancement
50. Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking pp130Cas
51. Defective bone formation in Krox-20 mutant mice
52. Regulation of type I collagen genes expression