Depolarization-induced slow current in cerebellar Purkinje cells does not require metabotropic glutamate receptor 1

Neuroscience

Volumn 162, Issue 3, 2009, Pages 688-693

  Shin, J H ^a   Kim, Y S ^a   Worley, P F ^a   Linden, D J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

autocrine; CPCCOEt; DHPG; mGluR5

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; ADENOSINE TRIPHOSPHATASE INHIBITOR; CALCIUM ION; GLUTAMATE RECEPTOR AGONIST; GLUTAMATE RECEPTOR ANTAGONIST; GLUTAMIC ACID; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR 5; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; BRAIN SLICE; CALCIUM TRANSPORT; CELL ACTIVATION; CEREBELLUM; CLIMBING FIBER; CONTROLLED STUDY; DENDRITE; MOUSE; NERVE CELL MEMBRANE STEADY POTENTIAL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; PURKINJE CELL; SLOW INWARD CURRENT;

ANIMALS; ANIMALS, NEWBORN; BIOPHYSICS; CEREBELLUM; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; EXCITATORY AMINO ACID ANTAGONISTS; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; PATCH-CLAMP TECHNIQUES; PURKINJE CELLS; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 67650703838     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2009.01.044     Document Type: Article

References (19)

1. Ango F., Prezeau L., Muller T., Tu J.C., Xiao B., Worley P.F., Pin J.P., Bockaert J., and Fagni L. Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer. Nature 411 (2001) 962-965
2. 2+ ion permeability and single-channel properties of the metabotropic slow EPSC of rat Purkinje neurons. J Neurosci 24 (2004) 3563-3573
3. Canepari M., Papageorgiou G., Corrie J.E., Watkins C., and Ogden D. The conductance underlying the parallel fibre slow EPSP in rat cerebellar Purkinje neurones studied with photolytic release of L-glutamate. J Physiol 533 (2001) 765-772
4. Carroll F.Y., Stolle A., Beart P.M., Voerste A., Brabet I., Mauler F., Joly C., Antonicek H., Bockaert J., Muller T., Pin J.P., and Prezeau L. BAY36-7620: a potent non-competitive mGlu1 receptor antagonist with inverse agonist activity. Mol Pharmacol 59 (2001) 965-973
5. Crepel F. Developmental changes in retrograde messengers involved in depolarization-induced suppression of excitation at parallel fiber-Purkinje cell synapses in rodents. J Neurophysiol 97 (2007) 824-836
6. Duguid I.C., Pankratov Y., Moss G.W., and Smart T.G. Somatodendritic release of glutamate regulates synaptic inhibition in cerebellar Purkinje cells via autocrine mGluR1 activation. J Neurosci 27 (2007) 12464-12474
7. Duguid I.C., and Smart T.G. Retrograde activation of presynaptic NMDA receptors enhances GABA release at cerebellar interneuron-Purkinje cell synapses. Nat Neurosci 7 (2004) 525-533
8. Fukunaga I., Yeo C.H., and Batchelor A.M. The mGlu1 antagonist CPCCOEt enhances the climbing fibre response in Purkinje neurones independently of glutamate receptors. Neuropharmacology 52 (2007) 450-458
9. Grandes P., Mateos J.M., Ruegg D., Kuhn R., and Knopfel T. Differential cellular localization of three splice variants of the mGluR1 metabotropic glutamate receptor in rat cerebellum. Neuroreport 5 (1994) 2249-2252
10. Hartmann J., Dragicevic E., Adelsberger H., Henning H.A., Sumser M., Abramowitz J., Blum R., Dietrich A., Freichel M., Flockerzi V., Birnbaumer L., and Konnerth A. TRPC3 channels are required for synaptic transmission and motor coordination. Neuron 59 (2008) 392-398
11. Joly C., Gomeza J., Brabet I., Curry K., Bockaert J., and Pin J.P. Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1. J Neurosci 15 (1995) 3970-3981
12. Kim S.J., Kim Y.S., Yuan J.P., Petralia R.S., Worley P.F., and Linden D.J. Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1. Nature 426 (2003) 285-291
13. Mabire D., Coupa S., Adelinet C., Poncelet A., Simonnet Y., Venet M., Wouters R., Lesage A.S., Van Beijsterveldt L., and Bischoff F. Synthesis, structure-activity relationship, and receptor pharmacology of a new series of quinoline derivatives acting as selective, noncompetitive mGlu1 antagonists. J Med Chem 48 (2005) 2134-2153
14. Negyessy L., Vidnyanszky Z., Kuhn R., Knopfel T., Gorcs T.J., and Hamori J. Light and electron microscopic demonstration of mGluR5 metabotropic glutamate receptor immunoreactive neuronal elements in the rat cerebellar cortex. J Comp Neurol 385 (1997) 641-650
15. Pagano A., Ruegg D., Litschig S., Stoehr N., Stierlin C., Heinrich M., Floersheim P., Prezeau L., Carroll F., Pin J.P., Cambria A., Vranesic I., Flor P.J., Gasparini F., and Kuhn R. The non-competitive antagonists 2-methyl-6-(phenylethynyl)pyridine and 7-hydroxyiminocyclopropan[b]chromen-1a-carboxylic acid ethyl ester interact with overlapping binding pockets in the transmembrane region of group I metabotropic glutamate receptors. J Biol Chem 275 (2000) 33750-33758
16. Prezeau L., Gomeza J., Ahern S., Mary S., Galvez T., Bockaert J., and Pin J.P. Changes in the carboxyl-terminal domain of metabotropic glutamate receptor 1 by alternative splicing generate receptors with differing agonist-independent activity. Mol Pharmacol 49 (1996) 422-429
17. Shin J.H., Kim Y.S., and Linden D.J. Dendritic glutamate release produces autocrine activation of mGluR1 in cerebellar Purkinje cells. Proc Natl Acad Sci U S A 105 (2008) 746-750
18. Takechi H., Eilers J., and Konnerth A. A new class of synaptic response involving calcium release in dendritic spines. Nature 396 (1998) 757-760
19. Tempia F., Miniaci M.C., Anchisi D., and Strata P. Postsynaptic current mediated by metabotropic glutamate receptors in cerebellar Purkinje cells. J Neurophysiol 80 (1998) 520-528