Macromolecular organisation of recombinant Yersinia pestis F1 antigen and the effect of structure on immunogenicity

FEMS Immunology and Medical Microbiology

Volumn 21, Issue 3, 1998, Pages 213-221

  Miller, Julie ^a   Williamson, E Diane ^a   Lakey, Jeremy H ^b   Pearce, Martin J ^a   Jones, Steven M ^a   Titball, Richard W ^a  

^a DEFENCE SCIENCE AND TECHNOLOGY LABORATORY   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

F1 antigen; Polypeptide capsule; Yersinia pestis

Indexed keywords

ANTIGEN; PLAGUE VACCINE; POLYPEPTIDE; RECOMBINANT VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; CAPILLARY ELECTROPHORESIS; CIRCULAR DICHROISM; FEMALE; GEL FILTRATION CHROMATOGRAPHY; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGENICITY; INTRAMUSCULAR DRUG ADMINISTRATION; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PLAGUE; PRIORITY JOURNAL; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION; YERSINIA PESTIS;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CIRCULAR DICHROISM; FEMALE; HEAT; IMMUNIZATION; MICE; MICE, INBRED BALB C; MOLECULAR WEIGHT; PLAGUE; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SODIUM DODECYL SULFATE; YERSINIA PESTIS;

EID: 0031849316     PISSN: 09288244     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-8244(98)00063-7     Document Type: Article

References (23)

1. Perry, R.D. and Fetherston, J.D. (1997) Yersinia pestis - etiologic agent of plague. Clin. Microbiol. Rev. 10, 35-66.
2. Centers for Disease Control and Prevention (1996) Prevention of plague: recommendations of the Advisory Committee on Immunisation Practices (ACIP). MMWR 45, 1-15.
3. Titball, R.W., Howells, A.M., Oyston, P.C.F. and Williamson, E.D. (1997) Expression of the Yersinia pestis capsular antigen (F1 antigen) on the surface of an aroA mutant of Salmonella typhimurium induces high level protection against plague. Infect. Immun. 65, 1926-1930.
4. Galyov, E.E., Smirnov, O.Yu., Karlishev, A.V., Volkovoy, K.I., Denesyuk, A.I., Nazimov, L.V., Rubstov, K.S., Abramov, V.M., Dalvadyanz, S.M. and Zav'yalov, V.P. (1990) Nucleotide sequence of the Yersinia pestis gene encoding F1 antigen and the primary structure of the protein. FEBS Lett. 277, 230-232.
5. Galyov, E.E., Karlishev, A.V., Chernovskaya, T.V. Dolgikh, D.A., Smirnov, O.Yu., Volkovoy, K.I., Abramov, V.M. and Zav'yalov, V.P. (1991) Expression of the envelope antigen F1 of Yersinia pestis is mediated by the product of caf1 M gene having homology with the chaperone protein PapD of Escherichia coli. FEBS Lett. 286, 79-82.
6. Karlyshev, A.V., Galyov, E.E., Smirnov, O.Y., Guizayev, A.P., Abramov, V.M. and Zav'yalov, V.P. (1992) A new gene of the f1 operon of Y. pestis involved in the capsule biogenesis. FEBS Lett. 297, 77-80.
7. Karylshev, A.V., Galyov, E.E., Abramov, V.M. and Zav'yalov, V.P. (1992) Caf1 R gene and its role in the regulation of capsule formation of Y. pestis. FEBS Lett. 305, 37-40.
8. Williams, R.C., Gewurz, H. and Quie, P.G. (1972) Effects of fraction 1 from Yersinia pestis on phagocytosis in vitro. J. Infect. Dis. 126, 235-241.
9. Rodrigues, C.G., Carneiro, C.M.M., Barbosa, C.T.F. and Nogueira, R.A. (1992) Antigen F1 from Yersinia pestis forms aqueous channels in lipid bilayer membranes. Braz. J. Med. Biol. Res. 25, 75-79.
10. Simpson, W.J., Thomas, R.E. and Schwan, T.G. (1990) Recombinant capsular antigen (fraction 1) from Yersinia pestis induces a protective antibody response in BALB/C mice. Am. J. Trop. Med. Hyg. 43, 389-396.
11. Andrews, G.P., Heath, D.G., Anderson, G.W. Jr., Welkos, S.L. and Friedlander, A.M. (1996) Fraction 1 capsular antigen (F1) purification from Yersinia pestis CO92 and from an Escherichia coli recombinant strain and efficacy against lethal plague challenge. Infect. Immun. 64, 2180-2187.
12. Williamson, E.D., Eley, S.M., Griffin, K.F., Green, M., Russell, P., Leary, S.E.C., Oyston, P.C.F., Easterbrook, T., Reddin, R.M., Robinson, A. and Titball, R.W. (1995), A new improved sub-unit vaccine for plague : the basis of protection. FEMS Immunol. Microbiol. 12, 223-230.
13. Williamson, E.D., Eley, S.M., Stagg, A.J., Green, M., Russell, P. and Titball, R.W. (1997) A subunit vaccine elicits IgG in serum, spleen cell cultures and bronchial washings and protects immunised animals against pneumonic plague. Vaccine 15, 1079-1084.
14. Voronstov, E.D., Dubichev, A.G., Serdobintsev, L.N. and Naumov, A.V. (1990) Association-dissociation processes and supermolecular organisation of the capsule antigen (protein F1) of Yersinia pestis. Biomed. Sci. 1, 391-396.
15. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual, 2nd edn., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
16. Smith, P.K., Krohn, R.I., Hermanson, G.T., Mallia, A.K., Gartner, F.H., Provenzano, M.D., Fujimoto, E.K., Goeke, N.M., Olson, B.J., Klenk, D.C. (1985). Measurement of protein using bicinchoninic acid. Analyt. Biochem. 150, 76-85.
17. Russell, P., Eley, S.M., Hibbs, S.E., Manchee, R.J., Stagg, A.J. and Titball, R.W. (1995). A comparison of plague vaccine, USP and EV76 vaccine induced protection against Yersinia pestis in a murine model. Vaccine 13, 1551-1556.
18. Fasman, G.D. (1996) Circular Dichroism and the Conformational Analysis of Biomolecules. Plenum, New York.
19. Manning, D.G., Jarvis, F.G. and Milner, K.C. (1988) Biophys. Chem. 31, 77-86.
20. Zav'yalov, V., Denesyuk, A., Zav'yalova, G. and Korpela, T. (1995) Molecular modelling of the steric structure of the envelope F1 antigen of Yersinia pestis. Immunol. Lett. 45, 19-22.
21. Oyston, P.C.F., Williamson, E.D., Leary, S.E.C., Eley, S.M., Griffin, K.F. and Titball, R.W. (1995) Immunisation with live recombinant Salmonella typhimurium aroA producing F1 antigen protects against plague. Infect. Immun. 63, 563-568.
22. Veynblat, V.l., Titenko, M.M., Verenkov, M.S., Men'shov, P.I., Kormilitsyn, A.V., Mozharov, O.T., Shcherbakov, A.A., Vasenin, A.S. and Zadumina, S.Y. (1985) Characterisation of samples of capsular antigen separated from broth cultures of the EV strain of Yersinia pestis. Zh. Mikrobiol. Epidemiol. Immunol. 4, 19-23.
23. Martin, D.G., Jarvis, F.G. and Milner, K.C. (1967) Physiochemical and biological properties of sonically treated Vi antigen. J. Bacteriol. 94, 1411-1416.