Ultrastructural and immunocytochemical characterization of the rat non-preganglionic Edinger-Westphal nucleus

General and Comparative Endocrinology

Volumn 164, Issue 1, 2009, Pages 32-39

  Van Wijk, Diane C W A ^a   Xu, Lu ^a   Spiegelberg, Linda ^a   Struik, Roeland F ^a   Meijer, Kari H ^a   Gaszner, Balázs ^a,b   Kozicz, Tamás ^a   Roubos, Eric W ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^b UNIVERSITY OF PÉCS   (Hungary)

Author keywords

Cocaine and amphetamine regulated transcript peptide; Colocalization; Postembedding immunogold electron microscopy; Stress; Synaptology; Urocortin 1

Indexed keywords

COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; UROCORTIN I;

ADAPTATION; ANIMAL TISSUE; BRAIN NERVE CELL; CELL ORGANELLE; CELL SECRETION; CONTROLLED STUDY; EMBEDDING; FEEDING; GOLGI COMPLEX; IMMUNOCYTOCHEMISTRY; IMMUNOGOLD LABELING; MALE; MESENCEPHALON; MORPHOLOGY; NON PREGANGLIONIC EDINGER WESTPHAL NUCLEUS; NONHUMAN; PRIORITY JOURNAL; RAT; REVIEW; RODENT; ROUGH ENDOPLASMIC RETICULUM; SECRETORY GRANULE; STRESS; SYNAPSE; TISSUE FIXATION; ULTRASTRUCTURE;

EID: 67650608191     PISSN: 00166480     EISSN: 10956840     Source Type: Journal    
DOI: 10.1016/j.ygcen.2009.04.002     Document Type: Review

References (47)

1. Bachtell R.K., Tsivkovskaia N.O., and Ryabinin A.E. Strain differences in urocortin expression in the Edinger-Westphal nucleus and its relation to alcohol-induced hypothermia. Neuroscience 113 (2002) 421-434
2. van de Bovenkamp-Janssen M.C., Akhmadeev A., Kalimullina L., van Luijtelaar E.L.J.M., and Roubos E.W. Synaptology of the rostral reticular thalamic nucleus of absence epileptic WAG/Rij rats. Neurosci. Rev. 48 (2004) 21-31
3. Bittencourt J.C., Vaughan J., Arias C., Rissman R.A., Vale W.W., and Sawchenko P.E. Urocortin expression in rat brain: evidence against a pervasive relationship of urocortin-containing projections with targets bearing type 2 CRF receptors. J. Comp. Neurol. 415 (1999) 285-312
4. Burde R.M., and Williams F. Parasympathetic nuclei. Brain Res. 498 (1989) 371-375
5. Cavani J.A., Reiner A., Cuthbertson S.L., Bittencourt J.C., and Toledo C.A. Evidence that urocortin is absent from neurons of the Edinger-Westphal nucleus in pigeons. Braz. J. Med. Biol. Res. 36 (2003) 1695-1700
6. DeFelipe J., and Fariñas I. The pyramidal neuron of the cerebral cortex: morphological and chemical characteristics of the synaptic inputs. Prog. Neurobiol. 39 (1992) 563-607
7. Dannies P.S. Protein hormone storage in secretory granules: mechanisms for concentration and sorting. Endocr. Rev. 20 (1999) 3-21
8. Edinger L. Zehn Vorlesungen über den Bau der nervösen Centralorgane für Ärzte und Studierende (1885), F.C.W. Vogel Verlag, Leipzig
9. Garzón M., Vaughan R.A., Uhl G.R., Kuhar M.J., and Pickel V.M. Cholinergic axon terminals in the ventral tegmental area target a subpopulation of neurons expressing low levels of the dopamine transporter. J. Comp. Neurol. 410 (1999) 197-210
10. Gaszner B., Csernus V., and Kozicz T. Urocortinergic neurons respond in a differentiated manner to various acute stressors in the Edinger-Westphal nucleus. J. Comp. Neurol. 480 (2004) 170-179
11. Germano C.M., de Castro M., Rorato R., Laguna M.T., Antunes-Rodrigues J., Elias C.F., and Elias L.L. Time course effects of adrenalectomy and food intake on cocaine- and amphetamine-regulated transcript expression in the hypothalamus. Brain Res. 1166 (2007) 55-64
12. Holt O.J., Gallo F., and Griffiths G.M. Regulating secretory lysosomes. J. Biochem. 140 (2006) 7-12
13. Holstege G. Some anatomical observations on the projections from the hypothalamus to brainstem and spinal cord: an HRP and autoradiographic tracing study in the cat. J. Comp. Neurol. 260 (1987) 98-126
14. Hubert G.W., and Kuhar M.J. Colocalization of CART with substance P but not enkephalin in the rat nucleus accumbens. Brain Res. 1050 (2005) 8-14
15. Kitamura Y., Tanaka H., Motoike T., Ishii M., Williams S.C., Yanagisawa M., and Sakurai T. Distribution of neuropeptide W immunoreactivity and mRNA in adult rat brain. Brain Res. 1093 (2006) 123-134
16. de Kloet E.R., Joëls M., and Holsboer F. Stress and the brain: from adaptation to disease. Nat. Rev. Neurosci. 6 (2005) 463-475
17. Koylu E.O., Balkan B., Kuhar M.J., and Pogun S. Cocaine and amphetamine regulated transcript (CART) and the stress response. Peptides 27 (2006) 1956-6199
18. Kozicz T. Neurons colocalizing urocortin and cocaine and amphetamine-regulated transcript immunoreactivities are induced by acute lipopolysaccharide stress in the Edinger-Westphal nucleus in the rat. Neuroscience 116 (2003) 315-320
19. Kozicz T. On the role of urocortin 1 in the non-preganglionic Edinger-Westphal nucleus in stress adaptation. Gen. Comp. Endocrinol. 153 (2007) 235-240
20. Kozicz T., Yanaihara H., and Arimura A. Distribution of urocortin-like immunoreactivity in the central nervous system of the rat. J. Comp. Neurol. 391 (1998) 1-10
21. Kozicz T., Min L., and Arimura A. The activation of urocortin immunoreactive neurons in the Edinger-Westphal nucleus following acute pain stress in rats. Stress 4 (2001) 85-90
22. Loewy A.D., and Saper C.B. Edinger-Westphal nucleus: projections to the brain stem and spinal cord in the cat. Brain Res. 150 (1978) 1-27
23. Lui X.B. Subcellular distribution of AMPA and NMDA receptor subunit immunoreactivity in ventral posterior and reticular nuclei of rat and cat thalamus. J. Comp. Neurol. 388 (1997) 587-602
24. Lui X.B., and Jones E.G. Predominance of corticothalamic synaptic inputs to thalamic reticular nucleus neurons in the rat. J. Comp. Neurol. 414 (1999) 67-79
25. May P.J., Reiner A.J., and Ryabinin A.E. Comparison of the distributions of urocortin-containing and cholinergic neurons in the perioculomotor midbrain of the cat and macaque. J. Comp. Neurol. 507 (2008) 1300-1316
26. Ohara P.T., and Lieberman A.R. The thalamic reticular nucleus of the adult rat: experimental anatomical studies. J. Neurocytol. 14 (1985) 365-411
27. Ohara P.T. Synaptic organization of the thalamic reticular nucleus. J. Electron Microsc. Tech. 10 (1988) 283-293
28. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates (1997), New York Academic Press
29. Philpot K., and Smith Y. CART peptide and the mesolimbic dopamine system. Peptides 27 (2006) 1987-1992
30. Pickard G.E., Smeraski C.A., Tomlinson C.C., Banfield B.W., Kaufman J., Wilcox C.L., Enquist L.W., and Sollars P.J. Intravitral injection of the attenuated pseudorabies virus PRV Bartha results in infection of the hamster suprachiasmatic nucleus only by retrograde transsynaptic transport via autonomic circuits. J. Neurosci. 22 (2002) 2701-2710
31. Rogge G., Jones D., Hubert G.W., Lin Y., and Kuhar M.J. CART peptides: regulators of body weight, reward and other functions. Nat. Rev. Neurosci. 9 (2008) 747-758
32. Roubos E.W., and Moorer-van Delft C.M. Morphometric in vitro analysis of the control of the activity of the neurosecretory Dark Green Cells in the freshwater snail Lymnaea stagnalis (L.). Cell Tissue Res. 174 (1976) 221-231
33. Ryabinin A.E., Tsivkovskaia N.O., and Ryabinin S.A. Urocortin 1-containing neurons in the human Edinger-Westphal nucleus. Neuroscience 134 (2005) 1317-1323
34. Saper C.B., Loewy A.D., Swanson L.W., and Cowan W.M. Direct hypothalamo-autonomic connections. Brain Res. 117 (1976) 305-312
35. Skelton K.H., Owens M.J., and Nemeroff C.B. The neurobiology of urocortin. Regul. Pept. 93 (2000) 85-92
36. Smith Y., Kieval J., Couceyro P.R., and Kuhar M.J. CART peptide-immunoreactive neurons in the nucleus accumbens in monkeys: ultrastructural analysis, colocalization studies, and synaptic interactions with dopaminergic afferents. J. Comp. Neurol. 407 (1999) 491-511
37. Stanley S.A., Small C.J., Murphy K.G., Rayes E., Abbott C.R., Seal L.J., Morgan D.G.A., Sunter D., Dakin C.L., Kim M.S., Hunter R., Kuhar M., Ghatei M.A., and Bloom S.R. Actions of cocaine- and amphetamine-regulated transcript (CART) peptide on regulation of appetite and hypothalamo-pituitary axes in vitro and in vivo in male rats. Brain Res. 893 (2001) 186-194
38. Takase L.F., Barone J.R., and Nogueira M.I. Involvement of the caudal raphe nuclei in the feeding behavior of rats. Braz. J. Med. Biol. Res. 33 (2000) 223-228
39. Tsigos C., and Chrousos G.P. Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress. J. Psychosom. Res. 53 (2002) 865-871
40. Wang L.C., Meijer H.K., Humbel B.M., Jenks B.G., and Roubos E.W. Activity-dependent dynamics of coexisting brain-derived neurotrophic factor, pro-opiomelanocortin and alpha-melanophore-stimulating hormone in melanotrope cells of Xenopus laevis. J. Neuroendocrinol. 16 (2004) 19-25
41. Wang C., and Kotz C.M. Urocortin in the lateral septal area modulates feeding induced by orexin A in the lateral hypothalamus. Am. J. Physiol. Regul. Integr. Comp. Physiol. 283 (2002) 358-367
42. Weninger S.C., Dunn A.J., Muglia L.J., Dikkes P., Miczek K.A., Swiergiel A.H., Berridge C.W., and Majzoub J.A. Stress-induced behaviors require the corticotropin-releasing hormone (CRH) receptor, but not CRH. Proc. Natl. Acad. Sci. USA 96 (1999) 8283-8288
43. Weninger S.C., Peters L.L., and Majzoub J.A. Urocortin expression in the Edinger-Westphal nucleus is up-regulated by stress and corticotropin-releasing hormone deficiency. Endocrinology 141 (2000) 256-263
44. Weitemier A.Z., Tsivkovskaia N.O., and Ryabinin A.E. Urocortin 1 distribution in mouse brain is strain-dependent. Neuroscience 132 (2005) 729-740
45. Weitemier A.Z., and Ryabinin A.E. Urocortin 1 in the dorsal raphe regulates food and fluid consumption, but not ethanol preference in C57BL/6J mice. Neuroscience 137 (2006) 1439-1445
46. Westphal C.F.O. Über einen Fall von chronischer progressiver Lähmung der Augenmuskeln (Ophthalmoplegia externa) nebst Beschreibung von Ganglienzellengruppen im Bereiche des Oculomotoriuskerns. Arch. Psychiat. Nervenkrankh. 18 (1887) 846-871
47. Zalutskaya A.A., Arai M., Bounoutas G.S., and Abou-Samra A.B. Impaired adaptation to repeated restraint and decreased response to cold in urocortin 1 knockout mice. Am. J. Physiol. Endocrinol. Metab. 293 (2007) 259-263