The antifungal agent itraconazole induces the accumulation of high mannose glycoproteins in macrophages

Journal of Biological Chemistry

Volumn 284, Issue 25, 2009, Pages 16882-16890

  Frey, Tiffany ^a   de Maio, Antonio ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION PROCESS; ANTI-FUNGAL; ANTIFUNGAL AGENTS; ANTIFUNGALS; BIOSYNTHETIC PATHWAY; CELL SURFACES; CELLULAR FUNCTION; CONCANAVALIN A; GLYCOSYLPHOSPHATIDYLINOSITOL; ITRACONAZOLE; LIPOPOLYSACCHARIDE; MYELOID CELLS; RECEPTOR SYSTEM; SEPTIC SHOCKS; SURFACE GLYCOPROTEINS; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTORS;

CELL MEMBRANES; ESTERIFICATION; GLYCOSYLATION; MACROPHAGES; MEDICAL PROBLEMS; POLYSACCHARIDES; PROTEINS;

GLYCOPROTEINS;

ALPHA METHYL MANNOSIDE; CD14 ANTIGEN; CHOLESTEROL; CONCANAVALIN A; ECONAZOLE; GLYCAN; GLYCOPROTEIN; ITRACONAZOLE; KETOCONAZOLE; LECTIN; LIPOPOLYSACCHARIDE; MANNOSE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; BIOACCUMULATION; CARBOHYDRATE SYNTHESIS; CELL FUNCTION; CELL SURFACE; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; GLYCOSYLATION; HOMEOSTASIS; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT;

ANIMALS; ANTIFUNGAL AGENTS; ANTIGENS, CD14; CELL LINE; CELL MEMBRANE; CHOLESTEROL; CONCANAVALIN A; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; ITRACONAZOLE; LIPOPOLYSACCHARIDES; MACROPHAGES; MACROPHAGES, PERITONEAL; MANNOSE; MICE; MICE, INBRED C57BL; PROTEIN PROCESSING, POST-TRANSLATIONAL; SOLUBILITY; TUMOR NECROSIS FACTOR-ALPHA;

BACTERIA (MICROORGANISMS); NEGIBACTERIA;

EID: 67650556449     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.007609     Document Type: Article

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