-
1
-
-
0033372621
-
Evaluation of fibrosis and hepatitis C
-
Friedman S.L. Evaluation of fibrosis and hepatitis C. Am J Med 107 6B (1999) 27S-30S
-
(1999)
Am J Med
, vol.107
, Issue.6 B
-
-
Friedman, S.L.1
-
2
-
-
0033854016
-
Inhibition of transforming growth factor beta prevents progression of liver fibrosis and enhances hepatocyte regeneration in dimethylnitrosamine-treated rats
-
Nakamura T., Sakata R., Ueno T., et al. Inhibition of transforming growth factor beta prevents progression of liver fibrosis and enhances hepatocyte regeneration in dimethylnitrosamine-treated rats. Hepatology 32 2 (2000) 247-255
-
(2000)
Hepatology
, vol.32
, Issue.2
, pp. 247-255
-
-
Nakamura, T.1
Sakata, R.2
Ueno, T.3
-
3
-
-
0028109801
-
Transforming growth factor beta in tissue fibrosis
-
Border W.A., and Noble N.A. Transforming growth factor beta in tissue fibrosis. N Engl J Med 331 19 (1994) 1286-1292
-
(1994)
N Engl J Med
, vol.331
, Issue.19
, pp. 1286-1292
-
-
Border, W.A.1
Noble, N.A.2
-
4
-
-
0033602101
-
Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway
-
Ulloa L., Doody J., and Massague J. Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway. Nature 397 6721 (1999) 710-713
-
(1999)
Nature
, vol.397
, Issue.6721
, pp. 710-713
-
-
Ulloa, L.1
Doody, J.2
Massague, J.3
-
5
-
-
0034723290
-
Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury
-
Friedman S.L. Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J Biol Chem 275 (2000) 2247-2250
-
(2000)
J Biol Chem
, vol.275
, pp. 2247-2250
-
-
Friedman, S.L.1
-
6
-
-
0033592753
-
A preliminary study of long-term treatment with interferon gamma-1b and low-dose prednisolone in patients with idiopathic pulmonary fibrosis
-
Ziesche R., Hofbauer E., Wittmann K., et al. A preliminary study of long-term treatment with interferon gamma-1b and low-dose prednisolone in patients with idiopathic pulmonary fibrosis. N Engl J Med 341 17 (1999) 1264-1269
-
(1999)
N Engl J Med
, vol.341
, Issue.17
, pp. 1264-1269
-
-
Ziesche, R.1
Hofbauer, E.2
Wittmann, K.3
-
7
-
-
0025963882
-
High doses of recombinant alpha-interferon or gamma-interferon for chronic hepatitis C: a randomized, controlled trial
-
Saez-Royuela F., Porres J.C., Moreno A., et al. High doses of recombinant alpha-interferon or gamma-interferon for chronic hepatitis C: a randomized, controlled trial. Hepatology 13 2 (1991) 327-331
-
(1991)
Hepatology
, vol.13
, Issue.2
, pp. 327-331
-
-
Saez-Royuela, F.1
Porres, J.C.2
Moreno, A.3
-
8
-
-
33947362952
-
Final results of a double-blind, placebo-controlled trial of the anti-fibrotic efficacy of interferon-gamma 1b in chronic hepatitis C with advanced fibrosis or cirrhosis
-
Pockros P.J., Jeffers L., Afdhal N., et al. Final results of a double-blind, placebo-controlled trial of the anti-fibrotic efficacy of interferon-gamma 1b in chronic hepatitis C with advanced fibrosis or cirrhosis. Hepatology 45 3 (2007) 569-578
-
(2007)
Hepatology
, vol.45
, Issue.3
, pp. 569-578
-
-
Pockros, P.J.1
Jeffers, L.2
Afdhal, N.3
-
9
-
-
13544277793
-
Interferon gamma-1 for the treatment of chronic hepatitis C infection
-
[abstract]
-
Muir A.J., Sylvestre P.B., and Rockey D.C. Interferon gamma-1 for the treatment of chronic hepatitis C infection. [abstract]. Gastroenterology 124 Suppl 1 (2003) A 718
-
(2003)
Gastroenterology
, vol.124
, Issue.SUPPL. 1
-
-
Muir, A.J.1
Sylvestre, P.B.2
Rockey, D.C.3
-
10
-
-
20444375441
-
Pilot study of interferon gamma for chronic hepatitis C
-
Soza A., Heller T., Ghany M., et al. Pilot study of interferon gamma for chronic hepatitis C. J Hepatol 43 1 (2005) 67-71
-
(2005)
J Hepatol
, vol.43
, Issue.1
, pp. 67-71
-
-
Soza, A.1
Heller, T.2
Ghany, M.3
-
11
-
-
0025275991
-
Therapy of chronic hepatitis B with recombinant human alpha and gamma interferon
-
Di Bisceglie A.M., Rustgi A.K., Kassianides C., et al. Therapy of chronic hepatitis B with recombinant human alpha and gamma interferon. Hepatology 11 2 (1990) 266-270
-
(1990)
Hepatology
, vol.11
, Issue.2
, pp. 266-270
-
-
Di Bisceglie, A.M.1
Rustgi, A.K.2
Kassianides, C.3
-
12
-
-
0025942053
-
Treatment with human gamma interferon of chronic hepatitis B: comparative study with alpha interferon
-
Kakumu S., Ishikawa T., Mizokami M., et al. Treatment with human gamma interferon of chronic hepatitis B: comparative study with alpha interferon. J Med Virol 35 1 (1991) 32-37
-
(1991)
J Med Virol
, vol.35
, Issue.1
, pp. 32-37
-
-
Kakumu, S.1
Ishikawa, T.2
Mizokami, M.3
-
13
-
-
23644444883
-
Effect of interferon gamma on hepatic fibrosis in chronic hepatitis B virus infection: a randomized controlled study
-
Weng H.L., Wang B.E., Jia J.D., et al. Effect of interferon gamma on hepatic fibrosis in chronic hepatitis B virus infection: a randomized controlled study. Clin Gastroenterol Hepatol 3 8 (2005) 819-828
-
(2005)
Clin Gastroenterol Hepatol
, vol.3
, Issue.8
, pp. 819-828
-
-
Weng, H.L.1
Wang, B.E.2
Jia, J.D.3
-
14
-
-
34247394547
-
Progression of fibrosis in advanced chronic hepatitis C: evaluation by morphometric image analysis
-
Goodman Z.D., Becker R.L., Pockros P.J., et al. Progression of fibrosis in advanced chronic hepatitis C: evaluation by morphometric image analysis. Hepatology 45 4 (2007) 886-894
-
(2007)
Hepatology
, vol.45
, Issue.4
, pp. 886-894
-
-
Goodman, Z.D.1
Becker, R.L.2
Pockros, P.J.3
-
15
-
-
33749434087
-
Fibrosis as an end point for clinical trials in liver disease: a consensus report of the International Fibrosis Group
-
McHutchison J.G., Poynard T., Afdhal N., et al. Fibrosis as an end point for clinical trials in liver disease: a consensus report of the International Fibrosis Group. Clin Gastroenterol Hepatol 4 10 (2006) 1214-1220
-
(2006)
Clin Gastroenterol Hepatol
, vol.4
, Issue.10
, pp. 1214-1220
-
-
McHutchison, J.G.1
Poynard, T.2
Afdhal, N.3
-
16
-
-
57349116772
-
Prolonged therapy of advanced chronic hepatitis C with low-dose peginterferon
-
Di Bisceglie A.M., Shiffman M.L., Everson G.T., et al. Prolonged therapy of advanced chronic hepatitis C with low-dose peginterferon. N Engl J Med 359 23 (2008) 2429-2441
-
(2008)
N Engl J Med
, vol.359
, Issue.23
, pp. 2429-2441
-
-
Di Bisceglie, A.M.1
Shiffman, M.L.2
Everson, G.T.3
-
17
-
-
33749425881
-
High early viral response (EVR) with PEG-Intron/Rebetol (PR) weight based dosing (WBD) in previous interferon/ribavirin HCV treatment failures; early results of the EPIC3 trial
-
[abstract]
-
Poynard T., Schiff E., Terg R., et al. High early viral response (EVR) with PEG-Intron/Rebetol (PR) weight based dosing (WBD) in previous interferon/ribavirin HCV treatment failures; early results of the EPIC3 trial. [abstract]. Hepatology 40 Suppl 1 (2004) 238A
-
(2004)
Hepatology
, vol.40
, Issue.SUPPL. 1
-
-
Poynard, T.1
Schiff, E.2
Terg, R.3
-
18
-
-
67349172961
-
Peginterferon alfa-2b and ribavirin: effective in patients with hepatitis C who failed interferon alfa/ribavirin therapy
-
Poynard T., Colombo M., Bruix J., et al. Peginterferon alfa-2b and ribavirin: effective in patients with hepatitis C who failed interferon alfa/ribavirin therapy. Gastroenterology 136 5 (2009) 1618-1628
-
(2009)
Gastroenterology
, vol.136
, Issue.5
, pp. 1618-1628
-
-
Poynard, T.1
Colombo, M.2
Bruix, J.3
-
19
-
-
53049097017
-
Colchicine versus peg-interferon alfa 2B long term therapy: results of the 4 year copilot trial
-
[abstract]
-
Afdhal N.H., Levine R., Brown Jr. R., et al. Colchicine versus peg-interferon alfa 2B long term therapy: results of the 4 year copilot trial. [abstract]. J Hepatol 48 Suppl 2 (2008) S4
-
(2008)
J Hepatol
, vol.48
, Issue.SUPPL. 2
-
-
Afdhal, N.H.1
Levine, R.2
Brown Jr., R.3
-
20
-
-
14844316890
-
Colchicine versus PEG-Intron long term (COPILOT) trial: interim analysis of clinical outcomes at year 2
-
[abstract]
-
Afdhal N., Frelich B., Levine R., et al. Colchicine versus PEG-Intron long term (COPILOT) trial: interim analysis of clinical outcomes at year 2. [abstract]. Hepatology 40 (2004) 239A
-
(2004)
Hepatology
, vol.40
-
-
Afdhal, N.1
Frelich, B.2
Levine, R.3
-
21
-
-
53049094134
-
Suppression of serum HCV RNA levels during maintenance peginterferon (PEG-IFN) alfa-2a therapy and clinical outcomes in the HALT-C trial
-
[abstract]
-
Shiffman M.L., Morishima C., Lindsay K.L., et al. Suppression of serum HCV RNA levels during maintenance peginterferon (PEG-IFN) alfa-2a therapy and clinical outcomes in the HALT-C trial. [abstract]. J Hepatol 48 Suppl 2 (2008) S62
-
(2008)
J Hepatol
, vol.48
, Issue.SUPPL. 2
-
-
Shiffman, M.L.1
Morishima, C.2
Lindsay, K.L.3
-
22
-
-
21044445452
-
Apoptosis: a mechanism of acute and chronic liver injury
-
Guicciardi M.E., and Gores G.J. Apoptosis: a mechanism of acute and chronic liver injury. Gut 54 7 (2005) 1024-1033
-
(2005)
Gut
, vol.54
, Issue.7
, pp. 1024-1033
-
-
Guicciardi, M.E.1
Gores, G.J.2
-
24
-
-
1242336980
-
Apoptosis: the nexus of liver injury and fibrosis
-
Canbay A., Friedman S., and Gores G.J. Apoptosis: the nexus of liver injury and fibrosis. Hepatology 39 2 (2004) 273-278
-
(2004)
Hepatology
, vol.39
, Issue.2
, pp. 273-278
-
-
Canbay, A.1
Friedman, S.2
Gores, G.J.3
-
25
-
-
0034808023
-
Caspase activation correlates with the degree of inflammatory liver injury in chronic hepatitis C virus infection
-
Bantel H., Lugering A., Poremba C., et al. Caspase activation correlates with the degree of inflammatory liver injury in chronic hepatitis C virus infection. Hepatology 34 4 Pt 1 (2001) 758-767
-
(2001)
Hepatology
, vol.34
, Issue.4 PART 1
, pp. 758-767
-
-
Bantel, H.1
Lugering, A.2
Poremba, C.3
-
26
-
-
0035552883
-
Fas-mediated hepatocyte apoptosis is increased by hepatitis C virus infection and alcohol consumption, and may be associated with hepatic fibrosis: mechanisms of liver cell injury in chronic hepatitis C virus infection
-
Pianko S., Patella S., Ostapowicz G., et al. Fas-mediated hepatocyte apoptosis is increased by hepatitis C virus infection and alcohol consumption, and may be associated with hepatic fibrosis: mechanisms of liver cell injury in chronic hepatitis C virus infection. J Viral Hepat 8 6 (2001) 406-413
-
(2001)
J Viral Hepat
, vol.8
, Issue.6
, pp. 406-413
-
-
Pianko, S.1
Patella, S.2
Ostapowicz, G.3
-
27
-
-
2142810153
-
Characterization of IDN-6556 (3-[2-(2-tert-butyl-phenylaminooxalyl)-amino]-propionylamino]-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic acid): a liver-targeted caspase inhibitor
-
Hoglen N.C., Chen L.S., Fisher C.D., et al. Characterization of IDN-6556 (3-[2-(2-tert-butyl-phenylaminooxalyl)-amino]-propionylamino]-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic acid): a liver-targeted caspase inhibitor. J Pharmacol Exp Ther 309 2 (2004) 634-640
-
(2004)
J Pharmacol Exp Ther
, vol.309
, Issue.2
, pp. 634-640
-
-
Hoglen, N.C.1
Chen, L.S.2
Fisher, C.D.3
-
28
-
-
1342329725
-
The caspase inhibitor IDN-6556 attenuates hepatic injury and fibrosis in the bile duct ligated mouse
-
Canbay A., Feldstein A., Baskin-Bey E., et al. The caspase inhibitor IDN-6556 attenuates hepatic injury and fibrosis in the bile duct ligated mouse. J Pharmacol Exp Ther 308 3 (2004) 1191-1196
-
(2004)
J Pharmacol Exp Ther
, vol.308
, Issue.3
, pp. 1191-1196
-
-
Canbay, A.1
Feldstein, A.2
Baskin-Bey, E.3
-
29
-
-
34548336791
-
Oral IDN-6556, an antiapoptotic caspase inhibitor, lowers aminotransferases in patients with chronic hepatitis C
-
Pockros P.J., Schiff E.R., Shiffman M.L., et al. Oral IDN-6556, an antiapoptotic caspase inhibitor, lowers aminotransferases in patients with chronic hepatitis C. Hepatology 46 2 (2007) 324-329
-
(2007)
Hepatology
, vol.46
, Issue.2
, pp. 324-329
-
-
Pockros, P.J.1
Schiff, E.R.2
Shiffman, M.L.3
-
30
-
-
67650510580
-
-
Available at: Identifier: NCT00725803. Accessed March 6, 2009
-
Available at:. ClinicalTrials.gov Identifier: NCT00725803. Accessed March 6, 2009
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