Synthesis, antimicrobial and antioxidant activities of some benzimidazole derivatives

Letters in Drug Design and Discovery

Volumn 6, Issue 5, 2009, Pages 374-379

  Kuş, Canan ^a   Ayhan Kilcigil, Gülgün ^a   Tunçbilek, Meral ^a   Altanlar, Nurten ^a   Çoban, Tülay ^a   Can Eke, Benay ^a   Işcan, Mümtaz ^a  

^a ANKARA UNIVERSITY   (Turkey)

Author keywords

Antimicrobial; Antioxidant; Benzimidazole; Synthesis

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; AMIDE; AMPICILLIN; BENZIMIDAZOLE DERIVATIVE; CAFFEINE; CYTOCHROME P450; ETHOXYRESORUFIN DEETHYLASE; N [3 (1H BENZIMIDAZOL 2 YL)PHENYL] 2 PHENYL 1H BENZIMIDAZOLE 5 CARBOXAMIDE; N [4 (1H BENZIMIDAZOL 2 YL)PHENYL] 2 PHENYL 1H BENZIMIDAZOLE 4 CARBOXAMIDE; N [4 (1H BENZIMIDAZOL 2 YL)PHENYL] 4 (1H BENZIMIDAZOL 2 YL) BENZAMIDE; SCAVENGER; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BACTERIUM ISOLATE; CANDIDA ALBICANS; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; IN VITRO STUDY; LIPID PEROXIDATION; LIVER MICROSOME; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 67650547428     PISSN: 15701808     EISSN: None     Source Type: Journal    
DOI: 10.2174/1570180810906050374     Document Type: Article

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25. 6) δ 7.24 (s, 2H), 7.35 (s, 2H), 7.57 (s, 2H), 7.65 (s, 2H), 8.01 (d, 2H, J= 8.4 Hz), 8.17 (m, 4H), 8.35 (d, 2H, J= 8.4 Hz), 10.59 (s, 1H).
26. 2O. Calc. (%) C: 60.45, H: 4.32, N: 13.05. Found (%) C: 60.06, H: 4.60, N: 13.43.
27. 6) δ 2.4 (s, 3H), 7.17 (d, 1H, J= 8.0 Hz), 7.50 (3H), 7.60 (d, 1H, J= 8.0 Hz), 7.76 (s, 2H), 8.12 (d, 2H, J= 7.8 Hz), 8.21 (d, 2H, J= 7.2 Hz), 8.25 (d, 2H, J= 7.8 Hz), 8.37 (d, 2H, J= 7.2 Hz), 10.81 (s, 1H).
28. 2O. Calc. (%) C: 60.23, H: 4.68, N: 13.01. Found (%) C: 60.00, H: 5.08, N: 13.12.
29. 2O. Calc. (%) C: 60.25, H: 4.96, N: 13.01. Found (%) C: 59.96, H: 5.30, N: 12.66.
30. 2O. Calc. (%) C: 61.10, H: 4.58, N: 12.72. Found (%) C: 61.06, H: 4.59, N: 12.97.
31. 2O. Calc. (%) C: 59.63, H: 4.73, N: 11.99. Found (%) C: 59.25, H: 4.62, N: 11.75.
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