Synthesis, antioxidant and radical scavenging activities of novel benzimidazoles

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 20, Issue 5, 2005, Pages 503-514

  Ayhan Kilcigil, Gülgün ^a   Kuş, Canan ^a   Çoban, Tülay ^a   Can Eke, Benay ^a   Özbey, Süheyla ^b   Iscan, Mümtaz ^a  

^a ANKARA UNIVERSITY   (Turkey)

^b HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Antioxidant activity; Radical scavenging; Thiadiazolylmethylbenzimidazoles; Thiosemicarbazides; Triazolylmethylbenzimidazoles; X ray structure analysis

Indexed keywords

1 [(3,4 DICHLOROPHENYLTHIOCARBAMOYLHYDRAZINECARBONYL)METHYL] 2 (4 PYRIDINYL) 1H BENZIMIDAZOLE; 1 [(4 METHOXYPHENYLTHIOCARBAMOYLHYDRAZINECARBONYL)METHYL] 2 (4 CHLOROPHENYL) 1H BENZIMIDAZOLE; 1 [(4 METHOXYPHENYLTHIOCARBAMOYLHYDRAZINECARBONYL)METHYL] 2 (4 METHOXYPHENYL) 1H BENZIMIDAZOLE; 1 [(4 METHOXYPHENYLTHIOCARBAMOYLHYDRAZINECARBONYL)METHYL] 2 (4 PYRIDINYL) 1H BENZIMIDAZOLE; 1 [(PHENYLTHIOCARBAMOYLHYDRAZINECARBONYL)METHYL] 2 (4 PYRIDINYL) 1H BENZIMIDAZOLE; 1,1 DIPHENYL 2 PICRYLHYDRAZYL; 5 [2 (4 CHLOROPHENYL)BENZIMIDAZOL 1 YLMETHYL] 4 METHOXYPHENYL 2,4 DIHYDRO[1,2,4]TRIAZOLE 3 THIONE; 5 [2 (4 METHOXYPHENYL)BENZIMIDAZOL 1 YLMETHYL] 4 METHOXYPHENYL 2,4 DIHYDRO[1,2,4]TRIAZOLE 3 THIONE; 5 [2 (4 PYRIDINYL)BENZIMIDAZOL 1 YLMETHYL] 3,4 DICHLOROPHENYL 2,4 DIHYDRO[1,2,4]TRIAZOLE 3 THIONE; 5 [2 (4 PYRIDINYL)BENZIMIDAZOL 1 YLMETHYL] 4 METHOXYPHENYL 2,4 DIHYDRO[1,2,4]TRIAZOLE 3 THIONE; 5 [2 (4 PYRIDINYL)BENZIMIDAZOL 1 YLMETHYL] 4 PHENYL 2,4 DIHYDRO[1,2,4]TRIAZOLE 3 THIONE; [5 [2 (4 CHLOROPHENYL)BENZIMIDAZOL 1 YLMETHYL][1,3,4]THIADIAZOLE 2 YL] 4 METHOXYPHENYLAMINE; [5 [2 (4 METHOXYPHENYL)BENZIMIDAZOL 1 YLMETHYL][1,3,4]THIADIAZOLE 2 YL] 4 METHOXYPHENYLAMINE; [5 [2 (4 PYRIDINYL)BENZIMIDAZOL 1 YLMETHYL][1,3,4]THIADIAZOLE 2 YL] 3,4 DICHLOROPHENYLAMINE; [5 [2 (4 PYRIDINYL)BENZIMIDAZOL 1 YLMETHYL][1,3,4]THIADIAZOLE 2 YL] 4 METHOXYPHENYLAMINE; [5 [2 (4 PYRIDINYL)BENZIMIDAZOL 1 YLMETHYL][1,3,4]THIADIAZOLE 2 YL]PHENYLAMINE; ANTIOXIDANT; BENZIMIDAZOLE DERIVATIVE; BUTYLCRESOL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SCAVENGER; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; IN VITRO STUDY; LIPID PEROXIDATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIOXIDANTS; BENZIMIDAZOLES; CRYSTALLOGRAPHY, X-RAY; FREE RADICAL SCAVENGERS; LIVER; MALE; MOLECULAR STRUCTURE; RATS; RATS, WISTAR; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA;

EID: 28244448473     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.1080/14756360500287086     Document Type: Article

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