Search for an association between V249I and T280M CX3CR1 genetic polymorphisms, endothelial injury and preeclampsia: The ECLAXIR study

PLoS ONE

Volumn 4, Issue 7, 2009, Pages

  Stepanian, Alain ^a,f   Benchenni, Soraya ^a   Beillat Lucas, Tiphaine ^b   Omnes, Sophie ^c   Defay, Fannie ^c   Peynaud Debayle, Edith ^a,f   Baron, Gabriel ^c   Le Querrec, Agnès ^d   Dreyfus, Michel ^b   Salomon, Laurence ^a   Tsatsaris, Vassillis ^e   de Prost, Dominique ^a,f,g   Mandelbrot, Laurent ^a,g   Foucher, E ^a   Gavard, L ^a   Lamotte, M ^a   Youmsi, E ^a   Azria, E ^e   Crespin, M ^e   Fontenay Roupie, M ^e   Goffinet, F ^e   Schmitz, F ^e   Cheret Benois, A ^b   Girard, B ^b   Herlicoviez, M ^b   Derlon, A ^d   Ajzenberg, N ^c   Huisse, M G ^c   Madelenat, P ^c   Mahieu Caputo, D ^c   Yazbeck, C ^c   Boudaoud, L ^h   Denninger, M H ^h   Desfeux, P ^h   Deval, B ^h   Levardon, M ^h   Samain, E ^h   Mokdad, A ⁱ   more..

^a HÔPITAL LOUIS MOURIER   (France)

^b CHU Clemenceau   (France)

^c BICHAT HOSPITAL   (France)

^d CHU CÔTE DE NACRE   (France)

^e université Paris Cité   (France)

^f CIB Phénogen du GHU Nord   (France)

^g UNIVERSITÉ PARIS DESCARTES   (France)

^h BEAUJON HOSPITAL   (France)

ⁱ Laboratoire de FIV   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CX3CR1; ISOLEUCINE; METHIONINE; THREONINE; THROMBOMODULIN; VALINE; VASCULAR CELL ADHESION MOLECULE 1; VON WILLEBRAND FACTOR; BIOLOGICAL MARKER; PRIMER DNA;

ADULT; AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; DISEASE MARKER; DISEASE SEVERITY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM INJURY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HOSPITAL BASED CASE CONTROL STUDY; HUMAN; MAJOR CLINICAL STUDY; MATERNAL BLOOD; ONSET AGE; PREECLAMPSIA; PREGNANT WOMAN; PROTEIN BLOOD LEVEL; REAL TIME POLYMERASE CHAIN REACTION; BLOOD; CASE CONTROL STUDY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; GENETICS; MULTICENTER STUDY; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; POLYMERASE CHAIN REACTION; PREGNANCY; VASCULAR ENDOTHELIUM;

ADULT; BASE SEQUENCE; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; DNA PRIMERS; ENDOTHELIUM, VASCULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PRE-ECLAMPSIA; PREGNANCY;

EID: 67650514322     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006192     Document Type: Article

References (39)

1. Sibai B, Dekker G, Kupferminc M (2005) Pre-eclampsia. Lancet 365: 785-799.
2. Granger JP, Alexander BT, Llinas MT, Bennett WA, Khalil RA (2001) Pathophysiology of hypertension during preeclampsia linking placental ischemia with endothelial dysfunction. Hypertension 38: 718-722.
3. Poston L (2006) Endothelial dysfunction in pre-eclampsia. Pharmacol Rep 58: 69-74.
4. Redman CW, Saks GP, Sargent IL (1999) Preeclampsia: an excessive maternal inflammatory response to pregnancy. Am J Obstet Gynecol 180: 499-506.
5. Umehara H, Bloom ET, Okazaki T, Nagano Y, Yoshie O, et al. (2004) Fractalkine in vascular biology: from basic research to clinical disease. Arteriocler Thromb Vasc Biol 24: 34-40.
6. Imai T, Hieshima K, Haskell C, Baba M, Nagira M, et al. (1997) Identification and molecular characterization of fractalkine receptor CX3CR1 which mediates both leukocyte migration and adhesion. Cell 91: 521-530.
7. Hannan NJ, Jones RL, Critchley HO, Kovacs GJ, Rogers PA, et al. (2004) Coexpression of fractalkine and its receptor in normal human endometrium and in endometrium from users of progestin-only contraception supports a role for fractalkine in leukocyte recruitment and endometrial remodeling. J Clin Endocrinol Metab 89: 6119-6129.
8. Hannan NJ, Jones RL, White CA, Salamonsen LA (2006) The chemokines, CX3CL1, CCL14, and CCL4, promote human trophoblast migration at the feto-maternal interface. Biol Reprod 74: 896-904.
9. Faure S, Meyer L, Costagliola D, Vaneensberghe C, Genin E, et al. (2000) Rapid progression to AIDS in HIV+ individuals with a structural variant of the chemokine receptor CX3CR1. Science 287: 2274-2277.
10. Moatti D, Faure S, Fumeron F, Amara MEW, Seknadji P, et al. (2001) Polymorphism in the fractalkine receptor CX3CR1 as a genetic risk factor for coronary artery disease. Blood 97: 1925-1928.
11. McDermott DH, Fong AM, Yang Q, Sechler JM, Cupples LA, et al. (2003) Chemokine receptor mutant CX3CR1-M280 has impaired adhesive function and correlates with protection from cardiovascular disease in humans. J Clin Invest 111: 1241-1250.
12. McDermott DH, Halcox JP, Schenke WH, Waclawiw MA, Merrell MN, et al. (2001) Association between polymorphism in the chemokine receptor CX3CR1 and coronary vascular endothelial dysfunction and atherosclerosis. Circ Res 89: 401-407.
13. 280 variant of the chemokine receptor CX3CR1. J Biol Chem 279: 19649-19657.
14. Irgens HU, Reisaeter L, Irgens LM, Lie RT (2001) Long term mortality of mothers and fathers after pre-eclampsia: population based cohort study. BMJ 323: 1213-1217.
15. Haukkamaa L, Salminen M, Laivuori H, Leinonen H, Hillesmaa V, et al. (2004) Risk of subsequent coronary artery disease after preeclampsia. Am J Cardiol 93: 805-808.
16. Magnussen EB, Vatten LJ, Lund-Nilsen TI, Salvesen KA, Smith GD, et al. (2007) Prepregnancy cardiovascular risk factors as predictors of pre-eclampsia: population based cohort study. BMJ 335: 978-986.
17. Ramsay JE, Stewart F, Greer IA, Sattar N (2003) Microvascular dysfunction: a link between preeclampsia and maternal coronary heart disease. BJOG 110: 1029-1031.
18. Roberts JM, Cooper DW (2001) Pathogenesis and genetics of pre-eclampsia. Lancet 357: 53-56.
19. Labarrere CA (1988) Acute atherosis. A histopathological hallmark of immune aggression? Placenta 9: 95-108.
20. ACOG (2002) Diagnosis and management of preeclampsia and eclampsia. ACOG Practice Bulletin/Int J Gynecol Obstet 77: 67-75.
21. Salomon LJ, Bernard JP, Ville Y (2007) Estimation of fetal weight: reference range at 20-36 weeks' gestation and comparison with actual birth-weight reference range. Ultrasound Obstet Gynecol 29: 550-555.
22. Sabate JM, Ameziane N, Lamoril J, Jouet P, Farmachidi JP, et al. (2008) The V249I polymorphism of the CX3CR1 gene is associated with fibrostenotic disease behavior in patients with Crohn's disease. Eur J Gastroenterol Hepatol 20: 748-755.
23. StephensM, Smith NJ, Donnelly P (2001) A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 68: 978-989.
24. Mutze S, Rudnik-Schoeneborn S, Zerres K, Rath W (2008) Genes and the preeclampsia syndrome. J Perinat Med 36: 38-58.
25. Chappell S, Morgan L (2006) Searching for genetic clues to the causes of preeclampsia. Clinical Science 110: 448.
26. Zintzaras E, Kitsios G, Harrison GA, Laivuori H, Kivinen K, et al. (2006) Heterogeneity-based genome search meta-analysis for preeclampsia. Hum Genet 120: 360-370.
27. DeVries ME, Cao H, Wang J, Xu L, Kelvin AA, et al. (2003) Genomic organization and evolution of the CX3CR1/CCR8 chemokine receptor locus. J Biol Chem 278: 11985-11994.
28. Maho A, Bensimon A, Vassart G, Parmentier M (1999) Mapping of the CCXCR1, CX3CR1, CCBP2 and CCR9 genes to the CCR cluster within the 3p21.3 region of the human genome. Cytogenet Cell Genet 87: 265-268.
29. Roberts JM, Gammill HS (2005) Preeclamspia: Recent insights. Hypertension 46: 1243-1249.
30. Cockwell P, Cjakravorty SJ, Girdlestone J, Savage CO (2002) Fractalkine expression in human renal inflammation. J Pathol 196: 85-90.
31. 3CR1 reveals a role for fractalkine in cardiac allograft rejection. J Clin Invest 108: 679-688.
32. Cybulsky MI, Hegele RA (2003) The fractalkine receptor CX3CR1 is a key mediator of atherogenesis. J Clin Invest 111: 1118-1120.
33. Lesnik P, Haskell CA, Charo IF (2003) Decreased atherosclerosis in CX3CR1 - / - mice reveals a role for fractalkine in atherogenesis. J Clin Invest 111: 333-340.
34. Shimoya K, Zhang Q, Tenna K, Ota Y, Hashimoto K, et al. (2003) Fractalkine (FRK) levels in amniotic fluid and its production during pregnancy. Mol Hum Reprod 9: 97-101.
35. Hannan NJ, Salamonsen LA (2008) CX3CL1 and CCL14 regulate extracellular matrix and adhesion molecules in the trophoblast: potential roles in human embryon implantation. Biol Reprod 79: 58-65.
36. Dominguez F, Yanez-Mo M, Sanchez-Madrid F, Simon C (2005) Embryonic implantation and leukocyte transendothelial migration: different processes with similar players? FASEB J 19: 1056-1060.
37. Landsman L, Bar-On L, Zernecke A, Kim KW, Krauthgamer R, et al. (2009) CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival. Blood 113: 963-972.
38. Lee SJ, Namkoong S, Kim YM, Kim CK, Lee H, et al. (2006) Fractalkine stimulates angiogenesis by activating the Raf-1/MEK/ERK- and PI3K/Akt/ eNOS-dependent signal pathways. Am J Physiol Heart Circ Physiol 291: H2836-H2846.
39. Tjoa ML, Levine RJ, Karumanchi SA (2007) Angiogenic factors and preeclampsia. Front Biosci 12: 2402.