Zinc deficiency increases organ damage and mortality in a murine model of polymicrobial sepsis

Critical Care Medicine

Volumn 37, Issue 4, 2009, Pages 1380-1388

  Knoell, Daren L ^a,b   Julian, Mark W ^a   Bao, Shengying ^a   Besecker, Beth ^a   MacRe, Jennifer E ^a   Leikauf, George D ^c   Disilvestro, Robert A ^b   Crouser, Elliott D ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Cecal ligation and puncture; Cell injury; Inflammation; Multiple organ dysfunction score; Oxidants

Indexed keywords

CYTOKINE; ZINC;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CECUM; CELL DEATH; CONTROLLED STUDY; IMMUNE RESPONSE; INFLAMMATION; LIGATION; LIVER; LUNG INJURY; MALE; MORTALITY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SEPSIS; SHAM PROCEDURE; SPLEEN INJURY; TISSUE INJURY; ZINC DEFICIENCY;

ANIMALS; DISEASE MODELS, ANIMAL; MALE; MICE; MICE, INBRED C57BL; MULTIPLE ORGAN FAILURE; SEPSIS; ZINC;

EID: 67650507043     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31819cefe4     Document Type: Article

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