Inhibition of cell death results in hyperganglionosis: Implications for enteric nervous system development

Neurogastroenterology and Motility

Volumn 21, Issue 7, 2009, Pages

  Wallace, A S ^a   Barlow, A J ^a,c   Navaratne, L ^a   Delalande, J M ^a,d   Tauszig Delamasure, S ^b   Corset, V ^b   Thapar, N ^a   Burns, A J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b CNRS   (France)

^c STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

^d EMORY UNIVERSITY   (United States)

Author keywords

Cell death; Chick embryo; Development; Enteric nervous system; Neural crest cells

Indexed keywords

BIOTIN; CASPASE 3; CASPASE 9; DIHYDROLIPOAMIDE DEHYDROGENASE; DNA NUCLEOTIDYLEXOTRANSFERASE; GREEN FLUORESCENT PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL LABELING; CELL MIGRATION; CELL POPULATION; CHICK EMBRYO; CONTROLLED STUDY; ELECTROPORATION; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; IMMUNOREACTIVITY; INTESTINE; INTESTINE INNERVATION; NATURAL KILLER CELL; NERVE CELL CULTURE; NERVOUS SYSTEM DEVELOPMENT; NEURAL CREST CELL; NEURAL TUBE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; STAINING; VAGUS NERVE;

ANIMALS; APOPTOSIS; BODY PATTERNING; CHICK EMBRYO; ELECTROPORATION; ENTERIC NERVOUS SYSTEM; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; NADPH DEHYDROGENASE; NEURONS; STEM CELLS;

EID: 67650501260     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/j.1365-2982.2009.01309.x     Document Type: Article

References (51)

1. Furness JB. The Enteric Nervous System. Oxford : Blackwell Publishing, 2006.
2. Yntema CL, Hammond WS. The origin of intrinsic ganglia of trunk viscera from vagal neural crest in the chick embryo. J Comp Neurol 1954 101 : 515 41.
3. Le Douarin NM, Teillet MA. The migration of neural crest cells to the wall of the digestive tract in avian embryo. J Embryol Exp Morphol 1973 30 : 31 48.
4. Burns AJ. Migration of neural crest-derived enteric nervous system precursor cells to and within the gastrointestinal tract. Int J Dev Biol 2005 49 : 143 50.
5. Kalcheim C, Le Douarin NM. The Neural Crest, 2nd edn. Cambridge : Cambridge University Press, 1999.
6. Young HM, Newgreen D, Burns AJ. The Development of the enteric nervous system in relation to Hirschsprung's disease. In : Ferretti P, Copp AJ, Tickle C, Moore G, eds. Embryos, Genes and Birth Defects, 2nd edn. Chichester : John Wiley and Sons, 2006 : 263 300.
7. Heanue TA, Pachnis V. Enteric nervous system development and Hirschsprung's disease: advances in genetic and stem cell studies. Nat Rev 2007 8 : 466 79.
8. Furness JB, Costa M. Types of nerves in the enteric nervous system. Neuroscience 1980 5 : 1 20. (Pubitemid 10203397)
9. Raff MC, Barres BA, Burne JF, Coles HS, Ishizaki Y, Jacobson MD. Programmed cell death and the control of cell survival: lessons from the nervous system. Science 1993 262 : 695 700.
10. Burek MJ, Oppenheim RW. Programmed cell death in the developing nervous system. Brain Pathol 1996 6 : 427 46.
11. Yuan J, Yankner BA. Apoptosis in the nervous system. Nature 2000 407 : 802 9.
12. Oppenheim RW. Cell death during development of the nervous system. Annu Rev Neurosci 1991 14 : 453 501.
13. Wade PR, Hornby PJ. Age-related neurodegenerative changes and how they affect the gut. Sci Aging Knowledge Environ 2005 2005 : pe8.
14. Cowen T, Johnson RJ, Soubeyre V, Santer RM. Restricted diet rescues rat enteric motor neurones from age related cell death. Gut 2000 47 : 653 60.
15. Wiley JW. Aging and neural control of the GI tract: III. Senescent enteric nervous system: lessons from extraintestinal sites and nonmammalian species. Am J Physiol Gastrointest Liver Physiol 2002 283 : G1020 6.
16. Gabella G. Fall in the number of myenteric neurons in aging guinea pigs. Gastroenterology 1989 96 : 1487 93.
17. Stanchina L, Baral V, Robert F et al. Interactions between Sox10, Edn3 and Ednrb during enteric nervous system and melanocyte development. Dev Biol 2006 295 : 232 49.
18. Aoki T, Jusuf AA, Iitsuka Y, Isono K, Tokuhisa T, Hatano M. Ncx (Enx, Hox11L.1) is required for neuronal cell death in enteric ganglia of mice. J Pediatr Surg 2007 42 : 1081 8.
19. Taraviras S, Marcos-Gutierrez CV, Durbec P et al. Signalling by the RET receptor tyrosine kinase and its role in the development of the mammalian enteric nervous system. Development 1999 126 : 2785 97.
20. Uesaka T, Jain S, Yonemura S, Uchiyama Y, Milbrandt J, Enomoto H. Conditional ablation of GFRalpha1 in postmigratory enteric neurons triggers unconventional neuronal death in the colon and causes a Hirschsprung's disease phenotype. Development 2007 134 : 2171 81.
21. Salvesen GS, Riedl SJ. Caspase mechanisms. Adv Exp Med Biol 2008 615 : 13 23.
22. Riedl SJ, Shi Y. Molecular mechanisms of caspase regulation during apoptosis. Nat Rev Mol Cell Biol 2004 5 : 897 907. (Pubitemid 39486541)
23. Boatright KM, Salvesen GS. Mechanisms of caspase activation. Curr Opin Cell Biol 2003 15 : 725 31.
24. Hamburger V, Hamilton HL. A series of normal stages in the development of chick embryo. J Morphol 1951 88 : 49 92.
25. Barlow AJ, Wallace AS, Thapar N, Burns AJ. Critical numbers of neural crest cells are required in the pathways from the neural tube to the foregut to ensure complete enteric nervous system formation. Development 2008 135 : 1681 91.
26. Smith VV, Eng C, Milla PJ. Intestinal ganglioneuromatosis and multiple endocrine neoplasia type 2B: implications for treatment. Gut 1999 45 : 143 6.
27. Lee NC, Norton JA. Multiple endocrine neoplasia type 2B - genetic basis and clinical expression. Surg Oncol 2000 9 : 111 8.
28. Raue F, Frank-Raue K. Multiple endocrine neoplasia type 2: 2007 update. Horm Res 2007 68 (Suppl 5 101 4.
29. Koletzko S, Jesch I, Faus-Kebetaler T et al. Rectal biopsy for diagnosis of intestinal neuronal dysplasia in children: a prospective multicentre study on interobserver variation and clinical outcome. Gut 1999 44 : 853 61.
30. Krammer HJ, Meier-Ruge W, Sigge W, Eggers R, Kuhnel W. Histopathological features of neuronal intestinal dysplasia of the plexus submucosus in whole mounts revealed by immunohistochemistry for PGP 9.5. Eur J Pediatr Surg 1994 4 : 358 61.
31. Meier-Ruge WA, Bruder E, Kapur RP. Intestinal neuronal dysplasia type B: one giant ganglion is not good enough. Pediatr Dev Pathol 2006 9 : 444 52.
32. Meier-Ruge WA, Ammann K, Bruder E et al. Updated results on intestinal neuronal dysplasia (IND B). Eur J Pediatr Surg 2004 14 : 384 91.
33. Shirasawa S, Yunker AM, Roth KA, Brown GA, Horning S, Korsmeyer SJ. Enx (Hox11L1)-deficient mice develop myenteric neuronal hyperplasia and megacolon. Nat Med 1997 3 : 646 50.
34. Hatano M, Aoki T, Dezawa M et al. A novel pathogenesis of megacolon in Ncx/Hox11L.1 deficient mice. J Clin Invest 1997 100 : 795 801. (Pubitemid 27371696)
35. Parisi MA, Baldessari AE, Iida MH et al. Genetic background modifies intestinal pseudo-obstruction and the expression of a reporter gene in Hox11L1-/- mice. Gastroenterology 2003 125 : 1428 40.
36. Gianino S, Grider JR, Cresswell J, Enomoto H, Heuckeroth RO. GDNF availability determines enteric neuron number by controlling precursor proliferation. Development 2003 130 : 2187 98.
37. White FA, Keller-Peck CR, Knudson CM, Korsmeyer SJ, Snider WD. Widespread elimination of naturally occurring neuronal death in Bax-deficient mice. J Neurosci 1998 18 : 1428 39.
38. Kirchgessner AL, Adlersberg MA, Gershon MD. Colonization of the developing pancreas by neural precursors from the bowel. Dev Dyn 1992 194 : 142 54.
39. Jiang Y, Liu MT, Gershon MD. Netrins and DCC in the guidance of migrating neural crest-derived cells in the developing bowel and pancreas. Dev Biol 2003 258 : 364 84.
40. Lahteenmaki M, Kupari J, Airaksinen MS. Increased apoptosis of parasympathetic but not enteric neurons in mice lacking GFRalpha2. Dev Biol 2007 305 : 325 32.
41. Airaksinen MS, Saarma M. The GDNF family: signalling, biological functions and therapeutic value. Nat Rev 2002 3 : 383 94.
42. Manie S, Santoro M, Fusco A, Billaud M. The RET receptor: function in development and dysfunction in congenital malformation. Trends Genet 2001 17 : 580 9.
43. Cacalano G, Farinas I, Wang LC et al. GFRalpha1 is an essential receptor component for GDNF in the developing nervous system and kidney. Neuron 1998 21 : 53 62. (Pubitemid 28355691)
44. de Giorgio R, Volta U, Stanghellini V et al. Neurogenic chronic intestinal pseudo-obstruction: antineuronal antibody-mediated activation of autophagy via Fas. Gastroenterology 2008 135 : 601 9.
45. Ventura-Martinez R, Santiago-Mejia J, Gomez C, Rodriguez R, Fortoul TI. Acute morphological changes in guinea-pig ileum myenteric neurons after ischemia in situ with superfusion in vitro. Pathol Res Pract 2008 204 : 121 7.
46. Mehlen P, Bredesen DE. The dependence receptor hypothesis. Apoptosis 2004 9 : 37 49. (Pubitemid 38270427)
47. Mehlen P. The dependence receptor notion: another way to see death. Cell Death Differ 2005 12 : 1003. (Pubitemid 41065416)
48. Bredesen DE, Mehlen P, Rabizadeh S. Receptors that mediate cellular dependence. Cell Death Differ 2005 12 : 1031 43.
49. Bordeaux MC, Forcet C, Granger L et al. The RET proto-oncogene induces apoptosis: a novel mechanism for Hirschsprung disease. EMBO J 2000 19 : 4056 63.
50. Schuchardt A, D'Agati V, Larsson-Blomberg L, Costantini F, Pachnis V. Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret. Nature 1994 367 : 380 3.
51. Plaza-Menacho I, Burzynski GM, de Groot JW, Eggen BJ, Hofstra RM. Current concepts in RET-related genetics, signaling and therapeutics. Trends Genet 2006 22 : 627 36.