Critically associating

Critical Care Medicine

Volumn 37, Issue 4, 2009, Pages 1492-1493

  Stalets, Erika ^a   Wong, Hector R ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Cytokines; Gene association; Immunity; In flammation; Polymorphisms; Sepsis

Indexed keywords

TUMOR NECROSIS FACTOR;

CRITICALLY ILL PATIENT; EDITORIAL; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; INTENSIVE CARE UNIT; MEDICAL SPECIALIST; MENINGOCOCCOSIS; NEISSERIA MENINGITIDIS; NONHUMAN; PRIORITY JOURNAL; SEPSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

CRITICAL ILLNESS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MENINGOCOCCAL INFECTIONS; POLYMORPHISM, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 67650498501     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31819d2be0     Document Type: Editorial

References (13)

1. Vincent JL, Abraham E: The last 100 years of sepsis. Am J Respir Crit Care Med 2006; 173:256-263
2. Arcaroli J, Fessler MB, Abraham E: Genetic polymorphisms and sepsis. Shock 2005; 24:300-312
3. Sorensen TI, Nielsen GG, Andersen PK, et al: Genetic and environmental influences on premature death in adult adoptees. N Engl J Med 1988; 318:727-732
4. Lorenz E, Mira JP, Cornish KL, et al: A novel polymorphism in the toll-like receptor 2 gene and its potential association with staphylococcal infection. Infect Immun 2000; 68:6398-6401
5. Agnese DM, Calvano JE, Hahm SJ, et al: Human toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of gram-negative infections. J Infect Dis 2002; 186:1522-1525
6. Lorenz E, Mira JP, Frees KL, et al: Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock. Arch Intern Med 2002; 162:1028-1032
7. O'Keefe GE, Hybki DL, Munford RS: The G->A single nucleotide polymorphism at the-308 position in the tumor necrosis factor-alpha promoter increases the risk for severe sepsis after trauma. J Trauma 2002; 52:817-825; discussion 825-826
8. Barber RC, Chang LY, Arnoldo BD, et al: Innate immunity SNPs are associated with risk for severe sepsis after burn injury. Clin Med Res 2006; 4:250-255
9. Read RC, Teare DM, Primidore AC, et al: The tumor necrosis factor polymorphism TNF (- 308) is associated with susceptibility to meningococcal sepsis, but not with lethality. Crit Care Med 2009; 37:1237-1243
10. Freely associating. Nat Genet 1999; 22:1-2
11. Clark MF, Baudouin SV: A systematic review of the quality of genetic association studies in human sepsis. Intensive Care Med 2006; 32:1706-1712
12. Sutherland AM, Russell JA: Issues with polymorphism analysis in sepsis. Clin Infect Dis 2005; 41 (Suppl 7):S396-S402
13. Mira JP, Cariou A, Grall F, et al: Association of TNF2, a TNF-alpha promoter polymorphism, with septic shock susceptibility and mortality: A multicenter study. JAMA 1999; 282:561-568