The evolution of carbon monoxide into medicine

Respiratory Care

Volumn 54, Issue 7, 2009, Pages 925-932

  Otterbein, Leo E ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Carbon monoxide; Homeostasis; Inflammation

Indexed keywords

CARBON MONOXIDE; CARBOXYHEMOGLOBIN; CYTOKINE; HEME OXYGENASE 1; HEME OXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; CELL PROLIFERATION; CELL STIMULATION; CONFERENCE PAPER; CYTOKINE PRODUCTION; DRUG EFFICACY; ENZYME ACTIVITY; HEART MUSCLE ISCHEMIA; HOMEOSTASIS; HUMAN; INFLAMMATION; INFLAMMATORY DISEASE; MEDICINE; NONHUMAN; ORGAN TRANSPLANTATION; PULMONARY HYPERTENSION; RESPIRATORY DISTRESS SYNDROME; SEPSIS; SIGNAL TRANSDUCTION;

EID: 67650462907     PISSN: 00201324     EISSN: None     Source Type: Journal    
DOI: 10.4187/002013209793800394     Document Type: Conference Paper

References (60)

1. Tenhunen R, Marver HS, Schmid R. Microsomal heme oxygenase. Characterization of the enzyme. J Biol Chem 1969;244(23):6388-6394.
2. Tenhunen R, Marver HS, Schmid R. The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc Natl Acad Sci USA 1968;61(2):748-755.
3. Van Muylem A, Knoop C, Estenne M. Early detection of chronic pulmonary allograft dysfunction by exhaled biomarkers. Am J Respir Crit Care Med 2007;175(7):731-736. (Pubitemid 46536490)
4. Zayasu K, Sekizawa K, Okinaga S, Yamaya M, Ohrui T, Sasaki H. Increased carbon monoxide in exhaled air of asthmatic patients. Am J Respir Crit Care Med 1997;156(4 Pt 1):1140-1143. (Pubitemid 27446519)
5. Yamaya M, Hosoda M, Ishizuka S, Monma M, Matsui T, Suzuki T, et al. Relation between exhaled carbon monoxide levels and clinical severity of asthma. Clin Exp Allergy 2001;31(3):417-422. (Pubitemid 34204162)
6. 2. I. Amino acids J Mol Evol 1983;19(5):376-382.
7. Maines MD, Trakshel GM, Kutty RK. Characterization of two constitutive forms of rat liver microsomal heme oxygenase. Only one molecular species of the enzyme is inducible. J Biol Chem 1986;261(1):411-419. (Pubitemid 16103962)
8. Braggins PE, Trakshel GM, Kutty RK, Maines MD. Characterization of two heme oxygenase isoforms in rat spleen: comparison with the hematin-induced and constitutive isoforms of the liver. Biochem Biophys Res Commun 1986;141(2):528-533. (Pubitemid 17001894)
9. Otterbein LE, Soares MP, Yamashita K, Bach FH. Heme oxygenase- 1: unleashing the protective properties of heme. Trends Immunol 2003;24(8):449-455. (Pubitemid 36928103)
10. Bach FH. Heme oxygenase-1 as a protective gene. Wiener Klin Wochenschr 2002;114(Suppl 4):1-3.
11. Lee TS, Chang CC, Zhu Y, Shyy JY. Simvastatin induces heme oxygenase-1: a novel mechanism of vessel protection. Circulation 2004;110(10):1296-1302. (Pubitemid 39202348)
12. Chen CY, Jang JH, Li MH, Surh YJ. Resveratrol upregulates heme oxygenase-1 expression via activation of NF-E2-related factor 2 in PC12 cells. Biochem Biophys Res Commun 2005;331(4):993-1000. (Pubitemid 40692459)
13. Jozkowicz A, Huk I, Nigisch A, Weigel G, Weidinger F, Dulak J. Effect of prostaglandin-J(2) on VEGF synthesis depends on the induction of heme oxygenase-1. Antioxid Redox Signal 2002;4(4):577-585.
14. Maines MD, Gibbs PE. 30 some years of heme oxygenase: from a "molecular wrecking ball" to a "mesmerizing" trigger of cellular events. Biochem Biophys Res Commun 2005;338(1):568-577.
15. Bilban M, Haschemi A, Wegiel B, Chin BY, Wagner O, Otterbein LE. Heme oxygenase and carbon monoxide initiate homeostatic signaling. J Mol Med 2008;86(3):267-279.
16. Otterbein LE, Zuckerbraun BS, Haga M, Liu F, Song R, Usheva A, et al. Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury. Nat Med 2003;9(2):183-190. (Pubitemid 36227720)
17. Otterbein LE, Mantell LL, Choi AM. Carbon monoxide provides protection against hyperoxic lung injury. Am J Physiol 1999;276(4 Pt 1):L688-L694. (Pubitemid 29211371)
18. Zuckerbraun BS, Billiar TR, Otterbein SL, Kim PK, Liu F, Choi AM, et al. Carbon monoxide protects against liver failure through nitric oxide-induced heme oxygenase 1. J Exp Med 2003;198(11):1707-1716. (Pubitemid 37494163)
19. Zhang X, Shan P, Otterbein LE, Alam J, Flavell RA, Davis RJ, et al. Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3. J Biol Chem 2003;278(2):1248-1258. (Pubitemid 36790808)
20. Suliman HB, Carraway MS, Ali AS, Reynolds CM, Welty-Wolf KE, Piantadosi CA. The CO/HO system reverses inhibition of mitochondrial biogenesis and prevents murine doxorubicin cardiomyopathy. J Clin Invest 2007;117(12):3730- 3741. (Pubitemid 350224084)
21. Wang HD, Yamaya M, Okinaga S, Jia YX, Kamanaka M, Takahashi H, et al. Bilirubin ameliorates bleomycin-induced pulmonary fibrosis in rats. Am J Respir Crit Care Med 2002;165(3):406-411. (Pubitemid 34118517)
22. Berberat PO, Katori M, Kaczmarek E, Anselmo D, Lassman C, Ke B, et al. Heavy chain ferritin acts as an antiapoptotic gene that protects livers from ischemia reperfusion injury. FASEB J 2003;17(12):1724-1726.
23. Poss KD, Tonegawa S. Heme oxygenase 1 is required for mammalian iron reutilization. Proc Natl Acad Sci USA 1997;94(20):10919-10924. (Pubitemid 27430836)
24. Poss KD, Tonegawa S. Reduced stress defense in heme oxygenase 1-deficient cells. Proc Natl Acad Sci USA 1997;94(20):10925-10930. (Pubitemid 27430837)
25. Otterbein LE, Bach FH, Alam J, Soares M, Tao Lu H, Wysk M, et al. Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med 2000;6(4):422-428. (Pubitemid 30208159)
26. Bilban M, Bach FH, Otterbein SL, Ifedigbo E, d'Avila J, Esterbauer H, et al. Carbon monoxide orchestrates a protective response through PPARgamma. Immunity 2006;24(5):601-610.
27. Mazzola S, Forni M, Albertini M, Bacci ML, Zannoni A, Gentilini F, et al. Carbon monoxide pretreatment prevents respiratory derangement and ameliorates hyperacute endotoxic shock in pigs. FASEB J 2005;19(14):2045-2047. (Pubitemid 41759760)
28. Sarady JK, Zuckerbraun BS, Bilban M, Wagner O, Usheva A, Liu F, et al. Carbon monoxide protection against endotoxic shock involves reciprocal effects on iNOS in the lung and liver. FASEB J 2004;18(7):854-856.
29. Otterbein LE. Carbon monoxide: innovative anti-inflammatory properties of an age-old gas molecule. Antioxid Redox Signal 2002;4(2):309-319. (Pubitemid 34517182)
30. Kim HS, Loughran PA, Kim PK, Billiar TR, Zuckerbraun BS. Carbon monoxide protects hepatocytes from TNF-alpha/Actinomycin D by inhibition of the caspase-8-mediated apoptotic pathway. Biochem Biophys Res Commun 2006;344(4):1172-1178.
31. Zhang X, Shan P, Alam J, Fu XY, Lee PJ. Carbon monoxide differentially modulates STAT1 and STAT3 and inhibits apoptosis via a phosphatidylinositol 3-kinase/Akt and p38 kinase-dependent STAT3 pathway during anoxia-reoxygenation injury. J Biol Chem 2005;280(10):8714-8721. (Pubitemid 40409558)
32. Soares MP, Usheva A, Brouard S, Berberat PO, Gunther L, Tobiasch E, et al. Modulation of endothelial cell apoptosis by heme oxygenase-1-derived carbon monoxide. Antioxid Redox Signal 2002;4(2):321-329. (Pubitemid 34517183)
33. Li Volti G, Sacerdoti D, Sangras B, Vanella A, Mezentsev A, Scapagnini G, et al. Carbon monoxide signaling in promoting angiogenesis in human microvessel endothelial cells. Antioxid Redox Signal 2005;7(5-6):704-710. (Pubitemid 40563210)
34. Chin BY, Jiang G, Wegiel B, Wang HJ, Macdonald T, Zhang XC, et al. Hypoxia-inducible factor 1alpha stabilization by carbon monoxide results in cytoprotective preconditioning. Proc Natl Acad Sci USA 2007;104(12):5109-5114. (Pubitemid 47186184)
35. Song R, Zhou Z, Kim PK, Shapiro RA, Liu F, Ferran C, et al. Carbon monoxide promotes Fas/CD95-induced apoptosis in Jurkat cells. J Biol Chem 2004;279(43):44327-44334. (Pubitemid 39430837)
36. Wegiel B, Chin BY, Otterbein LE. Inhale to survive, cycle or die? Carbon monoxide and cellular proliferation. Cell Cycle 2008;7(10):1379-1384. (Pubitemid 351872576)
37. Zuckerbraun BS, Chin BY, Wegiel B, Billiar TR, Czsimadia E, Rao J, et al. Carbon monoxide reverses established pulmonary hypertension. J Exp Med 2006;203(9):2109-2119. (Pubitemid 44352232)
38. Peyton KJ, Reyna SV, Chapman GB, Ensenat D, Liu XM, Wang H, et al. Heme oxygenase-1-derived carbon monoxide is an autocrine inhibitor of vascular smooth muscle cell growth. Blood 2002;99(12):4443-4448. (Pubitemid 34627213)
39. Song R, Mahidhara RS, Liu F, Ning W, Otterbein LE, Choi AM. Carbon monoxide inhibits human airway smooth muscle cell proliferation via mitogen-activated protein kinase pathway. Am J Respir Cell Mol Biol 2002;27(5):603-610. (Pubitemid 35301815)
40. Pamplona A, Ferreira A, Balla J, Jeney V, Balla G, Epiphanio S, et al. Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria. Nat Med 2007;13(6):703-710. (Pubitemid 46889755)
41. Scott JR, Chin BY, Bilban MH, Otterbein LE. Restoring HOmeostasis: is heme oxygenase-1 ready for the clinic? Trends Pharmacol Sci 2007;28(5):200-205.
42. Sato K, Balla J, Otterbein L, Smith RN, Brouard S, Lin Y, et al. Carbon monoxide generated by heme oxygenase-1 suppresses the rejection of mouse-to-rat cardiac transplants. J Immunol 2001;166(6):4185-4194. (Pubitemid 32224952)
43. Soares MP, Bach FH. Heme oxygenase-1 in organ transplantation. Front Biosci 2007;12:4932-4945.
44. Vreman HJ, Baxter LM, Stone RT, Stevenson DK. Evaluation of a fully automated end-tidal carbon monoxide instrument for breath analysis. Clin Chem 1996;42(1):50-56. (Pubitemid 26030381)
45. Chora AA, Fontoura P, Cunha A, Pais TF, Cardoso S, Ho PP, et al. Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation. J Clin Invest 2007;117(2):438-447. (Pubitemid 46203972)
46. Ryter SW, Otterbein LE. Carbon monoxide in biology and medicine. Bioessays 2004;26(3):270-280.
47. Kohmoto J, Nakao A, Sugimoto R, Wang Y, Zhan J, Ueda H, et al. Carbon monoxide-saturated preservation solution protects lung grafts from ischemia-reperfusion injury. J Thorac Cardiovasc Surg 2008;136(4):1067-1075.
48. Morisaki H, Katayama T, Kotake Y, Ito M, Handa M, Ikeda Y, et al. Carbon monoxide modulates endotoxin-induced microvascular leukocyte adhesion through platelet-dependent mechanisms. Anesthesiology 2002;97(3):701-709. (Pubitemid 34977331)
49. Nakao A, Kimizuka K, Stolz DB, Neto JS, Kaizu T, Choi AM, et al. Carbon monoxide inhalation protects rat intestinal grafts from ischemia/ reperfusion injury. Am J Pathol 2003;163(4):1587-1598. (Pubitemid 37175105)
50. Matsumoto H, Ishikawa K, Itabe H, Maruyama Y. Carbon monoxide and bilirubin from heme oxygenase-1 suppresses reactive oxygen species generation and plasminogen activator inhibitor-1 induction. Mol Cell Biochem 2006;291(1-2):21-28. (Pubitemid 44725298)
51. Lee SS, Gao W, Mazzola S, Thomas MN, Csizmadia E, Otterbein LE, et al. Heme oxygenase-1, carbon monoxide, and bilirubin induce tolerance in recipients toward islet allografts by modulating T regulatory cells. FASEB J 2007;21(13):3450-3457. (Pubitemid 350075135)
52. Chung SW, Hall SR, Perrella MA. Role of haem oxygenase-1 in microbial host defence. Cell Microbiol 2009;11(2):199-207.
53. Desmard M, Davidge KS, Bouvet O, Morin D, Roux D, Foresti R, et al. A carbon monoxide-releasing molecule (CORM-3) exerts bactericidal activity against Pseudomonas aeruginosa and improves survival in an animal model of bacteraemia. FASEB J 2009;23(4):1023-1031.
54. Otterbein LE, May A, Chin BY. Carbon monoxide increases macrophage bacterial clearance through Toll-like receptor (TLR)4 expression. Cell Mol Biol (Noisy-le-grand) 2005;51(5):433-440. (Pubitemid 41596299)
55. Ramlawi B, Scott JR, Feng J, Mieno S, Raman KG, Gallo D, et al. Inhaled carbon monoxide prevents graft-induced intimal hyperplasia in swine. J Surg Res 2007;138(1):121-127. (Pubitemid 46227462)
56. Fujimoto H, Ohno M, Ayabe S, Kobayashi H, Ishizaka N, Kimura H, et al. Carbon monoxide protects against cardiac ischemia-reperfusion injury in vivo via MAPK and Akt-eNOS pathways. Arterioscler Thromb Vasc Biol 2004;24(10):1848- 1853. (Pubitemid 39350302)
57. Nagasaka Y, Fernandez BO, Garcia-Saura MF, Petersen B, Ichinose F, Bloch KD, et al. Brief periods of nitric oxide inhalation protect against myocardial ischemia-reperfusion injury. Anesthesiology 2008;109(4):675-682.
58. Middelveld RJ, Alving K. Endotoxin-induced shock in the pig-limited effects of low and high concentrations of inhaled nitric oxide. Acta Physiol Scand 2003;179(2):203-211. (Pubitemid 37249254)
59. Frostell C, Fratacci MD, Wain JC, Jones R, Zapol WM. Inhaled nitric oxide. A selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction. Circulation 1991;83(6):2038-2047.
60. Bathoorn E, Slebos DJ, Postma DS, Koeter GH, van Oosterhout AJ, van der Toorn M, et al. Anti-inflammatory effects of inhaled carbon monoxide in patients with COPD: a pilot study. Eur Respir J 2007;30(6):1131-1137. (Pubitemid 351194760)