Structure-based targeting of bioactive proteins into cypovirus polyhedra and application to immobilized cytokines for mammalian cell culture

Biomaterials

Volumn 30, Issue 26, 2009, Pages 4297-4308

  Ijiri, Hiroshi ^a   Coulibaly, Fasséli ^b   Nishimura, Gento ^a   Nakai, Daisuke ^a   Chiu, Elaine ^c   Takenaka, Chiemi ^d   Ikeda, Keiko ^e   Nakazawa, Hiroshi ^e   Hamada, Norio ^a   Kotani, Eiji ^a   Metcalf, Peter ^c   Kawamata, Shin ^d   Mori, Hajime ^a,e  

^a KYOTO INSTITUTE OF TECHNOLOGY   (Japan)

^b MONASH UNIVERSITY   (Australia)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

^d FOUNDATION FOR BIOMEDICAL RESEARCH AND INNOVATION   (Japan)

^e Protein Crystal Corporation   (Japan)

Author keywords

Cypovirus; EGF; FGF 2; FGF 7; Keratinocytes; Polyhedra

Indexed keywords

CYPOVIRUS; EGF; FGF-2; FGF-7; KERATINOCYTES; POLYHEDRA;

AMINES; AMINO ACIDS; ANIMAL CELL CULTURE; BIOACTIVITY; CELL MEMBRANES; CONFOCAL MICROSCOPY; CRYSTAL ATOMIC STRUCTURE; FIBROBLASTS; GROWTH KINETICS; MAMMALS; ORGANIC ACIDS; PEPTIDES;

CELL CULTURE;

CYTOKINE; ENHANCED GREEN FLUORESCENT PROTEIN; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; KERATINOCYTE GROWTH FACTOR; POLYHEDRIN; RED FLUORESCENT PROTEIN;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL GROWTH; CONTROLLED STUDY; CYPOVIRUS; ENCAPSULATION; FIBROBLAST; HUMAN; HUMAN CELL; INSECT VIRUS; KERATINOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN IMMOBILIZATION; PROTEIN TARGETING;

ANIMALS; APOPTOSIS; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CYTOKINES; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR 7; GREEN FLUORESCENT PROTEINS; HUMANS; IMMOBILIZED PROTEINS; LUMINESCENT PROTEINS; MICE; MICROSCOPY, CONFOCAL; NIH 3T3 CELLS; PROTEIN STRUCTURE, SECONDARY; REOVIRIDAE; ULTRAVIOLET RAYS; VIRAL PROTEINS;

CYPOVIRUS; DISCOSOMA SP.; HEXAPODA; MAMMALIA;

EID: 67650438384     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.04.046     Document Type: Article

References (51)

1. MacBeath G., and Schreiber S.L. Printing proteins as microarrays for high-throughput function determination. Science 289 5485 (2000) 1760-1763
2. Rusmini F., Zhong Z., and Feijen J. Protein immobilization strategies for protein biochips. Biomacromolecules 8 6 (2007) 1775-1789
3. Zhu H., Bilgin M., Bangham R., Hall D., Casamayor A., Bertone P., et al. Global analysis of protein activities using proteome chips. Science 293 5537 (2001) 2101-2105
4. Belloncik S., and Mori H. Cypoviruses. In: Miller L.K., and Ball L.A. (Eds). The insect viruses (1998), Plenum Press, New York 337-369
5. Ikeda K., Nagaoka S., Winkler S., Kotani K., Yagi H., Nakanishi K., et al. Molecular characterization of Bombyx mori cytoplasmic polyhedrosis virus genome segment 4. J Virol 75 2 (2001) 988-995
6. Ikeda K., Nakazawa H., Shimo-Oka A., Ishio K., Miyata S., Hosokawa Y., et al. Immobilization of diverse foreign proteins in viral polyhedra and potential application for protein microarrays. Proteomics 6 1 (2006) 54-66
7. Mori H., Shukunami C., Furuyama A., Notsu H., Nishizaki Y., and Hiraki Y. Immobilization of bioactive fibroblast growth factor-2 into cubic proteinous microcrystals (Bombyx mori cypovirus polyhedra) that are insoluble in a physiological cellular environment. J Biol Chem 282 23 (2007) 17289-17296
8. Coulibaly F., Chiu E., Ikeda K., Gutmann S., Haebel P.W., Schulze-Briese C., et al. The molecular organization of cypovirus polyhedra. Nature 446 7131 (2007) 97-101
9. Yu X., Jin L., and Zhou Z.H. 3.88 A structure of cytoplasmic polyhedrosis virus by cryo-electron microscopy. Nature 453 7193 (2008) 415-419
10. Mori H., Ito R., Nakazawa H., Sumida M., Matsubara F., and Minobe Y. Expression of Bombyx mori cytoplasmic polyhedrosis virus polyhedrin in insect cells by using a baculovirus expression vector, and its assembly into polyhedra. J Gen Virol 74 1 (1993) 99-102
11. Kovalenko D., Yang X., Nadeau R.J., Harkins L.K., and Friesel R. Sef inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation. J Biol Chem 278 16 (2003) 14087-14091
12. Mackeigan J.P., Murphy L.O., Dimitri C.A., and Blenis J. Graded mitogen-activated protein kinase activity precedes switch-like c-Fos induction in mammalian cells. Mol Cell Biol 25 11 (2005) 4676-4682
13. Pages G., Lenormand P., L'Allemain G., Chambard J.C., Meloche S., and Pouyssegur J. Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation. Proc Natl Acad Sci U S A 90 18 (1993) 8319-8323
14. Zhan X., and Goldfarb M. Growth factor requirements of oncogene-transformed NIH 3T3 and BALB/c 3T3 cells cultured in defined medium. Mol Cell Biol 6 10 (1986) 3541-3544
15. Yamamoto T., Ebisuya M., Ashida F., Okamoto K., Yonehara S., and Nishida E. Continuous ERK activation downregulates antiproliferative genes throughout G1 phase to allow cell-cycle progression. Curr Biol 16 12 (2006) 1171-1182
16. Bailly K., Soulet F., Leroy D., Amalric F., and Bouche G. Uncoupling of cell proliferation and differentiation activities of basic fibroblast growth factor. FASEB J 14 2 (2000) 333-344
17. Metcalfe A.D., and Ferguson M.W. Tissue engineering of replacement skin: the crossroads of biomaterials, wound healing, embryonic development, stem cells and regeneration. J R Soc Interface 4 14 (2007) 413-437
18. Beer H.D., Bittner M., Niklaus G., Munding C., Max N., Goppelt A., et al. The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair. Oncogene 24 34 (2005) 5269-5277
19. Eming S.A., Krieg T., and Davidson J.M. Inflammation in wound repair: molecular and cellular mechanisms. J Invest Dermatol 127 3 (2007) 514-525
20. Haase I., Evans R., Pofahl R., and Watt F.M. Regulation of keratinocyte shape, migration and wound epithelialization by IGF-1- and EGF-dependent signalling pathways. J Cell Sci 116 15 (2003) 3227-3238
21. Pastore S., Mascia F., Mariani V., and Girolomoni G. The epidermal growth factor receptor system in skin repair and inflammation. J Invest Dermatol 128 6 (2008) 1365-1374
22. Werner S., and Grose R. Regulation of wound healing by growth factors and cytokines. Physiol Rev 83 3 (2003) 835-870
23. Dlugosz A.A., Cheng C., Denning M.F., Dempsey P.J., Coffey Jr. R.J., and Yuspa S.H. Keratinocyte growth factor receptor ligands induce transforming growth factor a expression and activate the epidermal growth factor receptor signaling pathway in cultured epidermal keratinocytes. Cell Growth Differ 5 12 (1994) 1283-1292
24. Igarashi M., Finch P.W., and Aaronson S.A. Characterization of recombinant human fibroblast growth factor (FGF)-10 reveals functional similarities with keratinocyte growth factor (FGF-7). J Biol Chem 273 21 (1998) 13230-13235
25. Luo Y., Ye S., Kan M., and McKeehan W.L. Control of fibroblast growth factor (FGF) 7- and FGF1-induced mitogenesis and downstream signaling by distinct heparin octasaccharide motifs. J Biol Chem 281 30 (2006) 21052-21061
26. Ornitz D.M., Xu J., Colvin J.S., McEwen D.G., MacArthur C.A., Coulier F., et al. Receptor specificity of the fibroblast growth factor family. J Biol Chem 271 25 (1996) 15292-15297
27. Schwarz A., Bhardwaj R., Aragane Y., Mahnke K., Riemann H., Metze D., et al. Ultraviolet-B-induced apoptosis of keratinocytes: evidence for partial involvement of tumor necrosis factor-a in the formation of sunburn cells. J Invest Dermatol 104 6 (1995) 922-927
28. Rosette C., and Karin M. Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors. Science 274 5290 (1996) 1194-1197
29. Sheikh M.S., Antinore M.J., Huang Y., and Fornace Jr. A.J. Ultraviolet-irradiation-induced apoptosis is mediated via ligand independent activation of tumor necrosis factor receptor 1. Oncogene 17 20 (1998) 2555-2563
30. Braun S., Krampert M., Bodo E., Kumin A., Born-Berclaz C., Paus R., et al. Keratinocyte growth factor protects epidermis and hair follicles from cell death induced by UV irradiation, chemotherapeutic or cytotoxic agents. J Cell Sci 119 23 (2006) 4841-4849
31. Lotti L.V., Rotolo S., Francescangeli F., Frati L., Torrisi M.R., and Marchese C. AKT and MAPK signaling in KGF-treated and UVB-exposed human epidermal cells. J Cell Physiol 212 3 (2007) 633-642
32. Spielberger R., Stiff P., Bensinger W., Gentile T., Weisdorf D., Kewalramani T., et al. Palifermin for oral mucositis after intensive therapy for hematologic cancers. N Engl J Med 351 25 (2004) 2590-2598
33. Werner S. Keratinocyte growth factor: a unique player in epithelial repair processes. Cytokine Growth Factor Rev 9 2 (1998) 153-165
34. Finch P.W., and Rubin J.S. Keratinocyte growth factor/fibroblast growth factor 7, a homeostatic factor with therapeutic potential for epithelial protection and repair. Adv Cancer Res 91 (2004) 69-136
35. Andreadis S.T., and Geer D.J. Biomimetic approaches to protein and gene delivery for tissue regeneration. Trends Biotechnol 24 7 (2006) 331-337
36. Boontheekul T., and Mooney D.J. Protein-based signaling systems in tissue engineering. Curr Opin Biotechnol 14 5 (2003) 559-565
37. Choi J.S., Leong K.W., and Yoo H.S. In vivo wound healing of diabetic ulcers using electrospun nanofibers immobilized with human epidermal growth factor (EGF). Biomaterials 29 5 (2008) 587-596
38. Kitajima T., Terai H., and Ito Y. A fusion protein of hepatocyte growth factor for immobilization to collagen. Biomaterials 28 11 (2007) 1989-1997
39. Macri L., Silverstein D., and Clark R.A. Growth factor binding to the pericellular matrix and its importance in tissue engineering. Adv Drug Deliv Rev 59 13 (2007) 1366-1381
40. Nur E.K.A., Ahmed I., Kamal J., Babu A.N., Schindler M., and Meiners S. Covalently attached FGF-2 to three-dimensional polyamide nanofibrillar surfaces demonstrates enhanced biological stability and activity. Mol Cell Biochem 309 1-2 (2008) 157-166
41. Rosso F., Marino G., Giordano A., Barbarisi M., Parmeggiani D., and Barbarisi A. Smart materials as scaffolds for tissue engineering. J Cell Physiol 203 3 (2005) 465-470
42. Stefonek T.J., and Masters K.S. Immobilized gradients of epidermal growth factor promote accelerated and directed keratinocyte migration. Wound Repair Regen 15 6 (2007) 847-855
43. Hubbell J. Matrix-bound growth factors in tissue repair. Swiss Med Wkly 136 25-26 (2006) 387-391
44. Hubbell J.A. Materials as morphogenetic guides in tissue engineering. Curr Opin Biotechnol 14 5 (2003) 551-558
45. Taipale J., and Keski-Oja J. Growth factors in the extracellular matrix. FASEB J 11 1 (1997) 51-59
46. Liu W.F., and Chen C.S. Cellular and multicellular form and function. Adv Drug Deliv Rev 59 13 (2007) 1319-1328
47. Davis M.E., Hsieh P.C., Grodzinsky A.J., and Lee R.T. Custom design of the cardiac microenvironment with biomaterials. Circ Res 97 1 (2005) 8-15
48. Page-McCaw A., Ewald A.J., and Werb Z. Matrix metalloproteinases and the regulation of tissue remodelling. Nat Rev Mol Cell Biol 8 3 (2007) 221-233
49. Salmivirta M., Heino J., and Jalkanen M. Basic fibroblast growth factor-syndecan complex at cell surface or immobilized to matrix promotes cell growth. J Biol Chem 267 25 (1992) 17606-17610
50. Sato M., Ishihara M., Kaneshiro N., Mitani G., Nagai T., Kutsuna T., et al. Effects of growth factors on heparin-carrying polystyrene-coated atelocollagen scaffold for articular cartilage tissue engineering. J Biomed Mater Res B Appl Biomater 83 1 (2007) 181-188
51. Schlessinger J., Plotnikov A.N., Ibrahimi O.A., Eliseenkova A.V., Yeh B.K., Yayon A., et al. Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization. Mol Cell 6 3 (2000) 743-750