Ion channel and toxin measurement using a high throughput lipid membrane platform

Biosensors and Bioelectronics

Volumn 24, Issue 6, 2009, Pages 1806-1810

  Poulos, Jason L ^a   Jeon, Tae Joon ^a   Damoiseaux, Robert ^b   Gillespie, Eugene J ^b   Bradley, Kenneth A ^b   Schmidt, Jacob J ^a,b  

^a University of California   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Biosensor; Drug discovery; Drug screening; High throughput; Ion channel; Lipid bilayer

Indexed keywords

DRIVING FORCES; DRUG DISCOVERY; DRUG SCREENING; HIGH THROUGHPUT; HIGH-THROUGHPUT METHOD; ION CHANNEL; LIPID MEMBRANES; LIPID MONOLAYER; LIPID VESICLES; PHARMACEUTICAL APPLICATIONS; PROOF OF CONCEPT; SELF-ASSEMBLED; SINGLE MOLECULE LEVEL; SINGLE MOLECULE MEASUREMENTS;

BIOSENSORS; COMBINES; IONS; PHASE INTERFACES; SELF ASSEMBLED MONOLAYERS; SULFUR COMPOUNDS; THROUGHPUT;

LIPID BILAYERS;

ALAMETHICIN; ALPHA HEMOLYSIN; ANTHRAX TOXIN; GRAMICIDIN; ION CHANNEL;

ACCURACY; ARTICLE; BIOSENSOR; CONTROLLED STUDY; DRUG SCREENING; HIGH THROUGHPUT SCREENING; LIPID BILAYER; LIPID MEMBRANE; MEMBRANE FORMATION; PROTEIN ANALYSIS; ROBOTICS;

BIOSENSING TECHNIQUES; ELECTROCHEMISTRY; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; ION CHANNELS; LIPID BILAYERS; MEMBRANES, ARTIFICIAL; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TOXICITY TESTS; TOXINS, BIOLOGICAL;

EID: 67650434222     PISSN: 09565663     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bios.2008.08.041     Document Type: Article

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