Initiation of antiretroviral therapy 48 hours after infection with simian immunodeficiency virus potently suppresses acute-phase viremia and blocks the massive loss of memory CD4+ T cells but fails to prevent disease

Journal of Virology

Volumn 83, Issue 14, 2009, Pages 7099-7108

  Kubo, Makoto ^a,b   Nishimura, Yoshiaki ^a   Shingai, Masashi ^a   Lee, Wendy ^a   Brenchley, Jason ^a   Lafont, Bernard ^a   Buckler White, Alicia ^a   Igarashi, Tatsuhiko ^a   Martin, Malcolm A ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b KITASATO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN CLASS 1; TENOFOVIR;

AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; GENE SEQUENCE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PRIORITY JOURNAL; RHESUS MONKEY; SIMIAN IMMUNODEFICIENCY VIRUS; TREATMENT DURATION; TREATMENT FAILURE; TREATMENT OUTCOME; VIREMIA; VIRUS INFECTION; VIRUS INHIBITION; VIRUS LOAD; VIRUS NEUTRALIZATION; VIRUS REPLICATION;

ADENINE; AMINO ACID SEQUENCE; ANIMALS; ANTI-HIV AGENTS; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; HIV ANTIBODIES; HIV INFECTIONS; HUMANS; INJECTIONS; MACACA MULATTA; MOLECULAR SEQUENCE DATA; PHOSPHONIC ACIDS; SEQUENCE ALIGNMENT; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; TIME FACTORS; VIREMIA; VIRUS REPLICATION;

ANIMALIA; MACACA; MACACA MULATTA; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 67650427450     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02522-08     Document Type: Article

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