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Volumn 44, Issue 9, 2009, Pages 3612-3620
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Synthesis and pharmacological evaluation of N-phenyl-acetamide sulfonamides designed as novel non-hepatotoxic analgesic candidates
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Author keywords
Analgesic; Hepatotoxicity; LASSBio 1300; N Phenyl acetamide sulfonamides; Paracetamol
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Indexed keywords
ANALGESIC AGENT;
FUNCTIONAL GROUP;
GAMMA GLUTAMYLTRANSFERASE;
LASSBIO 1295;
LASSBIO 1296;
LASSBIO 1297;
LASSBIO 1298;
LASSBIO 1299;
LASSBIO 1300;
LASSBIO 1301;
MORPHINE;
N [4 (DIETHYLAMINO 4 YLSULFONYL)PHENYL]ACETAMIDE;
N [4 (ETHYLAMINO 4 YLSULFONYL)PHENYL]ACETAMIDE;
N [4 (MORPHOLIN 4 YLSULFONYL)PHENYL]ACETAMIDE;
N [4 (PIPERAZIN 4 YLSULFONYL)PHENYL]ACETAMIDE;
N [4 (PIPERIDIN 4 YLSULFONYL)PHENYL]ACETAMIDE;
N [4 (THIOMORPHOLIN 4 YLSULFONYL)PHENYL]ACETAMIDE;
N [4 [(4 METHYL 1 PIPERAZINYL)SULFONYL]PHENYL]ACETAMIDE;
N PHENYLACETAMIDE SULFONAMIDE DERIVATIVE;
PARACETAMOL;
PARACETAMOL DERIVATIVE;
SULFONYL CHLORIDE DERIVATIVE;
UNCLASSIFIED DRUG;
ANALGESIC ACTIVITY;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANIMAL TISSUE;
ANTINOCICEPTION;
ARTICLE;
CONTROLLED STUDY;
DOSE RESPONSE;
DRUG DESIGN;
DRUG EFFECT;
DRUG STRUCTURE;
DRUG SYNTHESIS;
ENZYME ACTIVITY;
HISTOLOGY;
HOT PLATE TEST;
INFLAMMATION;
LIVER FUNCTION;
LIVER PARENCHYMA;
LIVER TOXICITY;
MOUSE;
NONHUMAN;
PAIN;
STEREOCHEMISTRY;
WRITHING TEST;
ACETANILIDES;
ANALGESICS;
ANIMALS;
BODY TEMPERATURE;
LIVER;
MICE;
MODELS, MOLECULAR;
PAIN MEASUREMENT;
SULFONAMIDES;
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EID: 67650424298
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2009.02.026 Document Type: Article |
Times cited : (19)
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References (37)
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